Q86ZU6 (GLNA_TUBBO) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Glutamine synthetase
Short name=GS
EC=6.3.1.2

Alternative name(s):
Glutamate--ammonia ligase

Gene names

Name:

GLN1

Organism

Tuber borchii (White truffle)

Taxonomic identifier

42251 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Fungi › Dikarya › Ascomycota › saccharomyceta › Pezizomycotina › Pezizomycetes › Pezizales › Tuberaceae › Tuber

Protein attributes

Sequence length	358 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Catalytic activity	ATP + L-glutamate + NH3 = ADP + phosphate + L-glutamine.
Subunit structure	Homooctamer By similarity.
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the glutamine synthetase family.

Ontologies

Keywords
Cellular component	Cytoplasm
Ligand	ATP-binding Nucleotide-binding
Molecular function	Ligase
Gene Ontology (GO)
Biological_process	glutamine biosynthetic process Inferred from electronic annotation. Source: InterPro
Cellular_component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW glutamate-ammonia ligase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 358	358	Glutamine synthetase		PRO_0000153164

Sequences

	Sequence		Length	Mass (Da)
	Q86ZU6 [UniParc]. Last modified June 1, 2003. Version 1. Checksum: 4BF82095152856E0	FASTA	358	39,664
	10 20 30 40 50 60 MSENSTIVSN TANLVKFLNL DQKGSILAEY IWIDGANGVR SKTKTLFKKP SSVEDLPEWN 70 80 90 100 110 120 FDGSSTGQAP GEDSDIYLRP VAIFPDPFRM GDNILVLAEC WNADGSPNKF NHRHECAKIM 130 140 150 160 170 180 EAHKDQKPWF GLEQEYTLFD LYGNPYGWPK GGFPGPQGPY YCGVGTGKVY CRDIVEAHYK 190 200 210 220 230 240 ACLFAGIKIS GINAEVLPSQ WEFQVGPCVG IEMGDHLWIS RYLLHRVAEE FGVKISFHPK 250 260 270 280 290 300 PIPGDWNGSG LHTNVSTQAM RDEGGMKAIE EAIQKLSTRH AEHIAVYGDD NTLRLTGRHE 310 320 330 340 350 TGNIDAFSYG VADRGSSIRI PRSCAKEGKG YFEDRRPASN ACPYQITGIM METICGGI

References

[1]	"Distinctive properties and expression profiles of glutamine synthetase from a plant symbiotic fungus." Montanini B., Betti M., Marquez A.J., Balestrini R., Bonfante P., Ottonello S. Biochem. J. 373:357-368(2003) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	AF462037 mRNA. Translation: AAP23163.1.
3D structure databases
ProteinModelPortal	Q86ZU6.
SMR	Q86ZU6. Positions 16-355.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Enzyme and pathway databases
BRENDA	6.3.1.2. 7423.
Family and domain databases
Gene3D	3.30.590.10. 1 hit.
InterPro	IPR008147. Gln_synt_beta. IPR014746. Gln_synth/guanido_kin_cat_dom. IPR008146. Gln_synth_cat_dom. IPR027303. Gln_synth_gly_rich_site. IPR027302. Gln_synth_N_conserv_site. [Graphical view]
Pfam	PF00120. Gln-synt_C. 1 hit. PF03951. Gln-synt_N. 1 hit. [Graphical view]
SUPFAM	SSF54368. Gln_synt_beta. 1 hit.
PROSITE	PS00180. GLNA_1. 1 hit. PS00181. GLNA_ATP. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GLNA_TUBBO

Accession

Primary (citable) accession number: Q86ZU6

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 13, 2004
Last sequence update:	June 1, 2003
Last modified:	May 1, 2013
This is version 37 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Fungal Protein Annotation Program