##gff-version 3
Q86YN6	UniProtKB	Chain	1	1023	.	.	.	ID=PRO_0000240158;Note=Peroxisome proliferator-activated receptor gamma coactivator 1-beta	
Q86YN6	UniProtKB	Domain	902	976	.	.	.	Note=RRM;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00176	
Q86YN6	UniProtKB	Region	1	91	.	.	.	Note=Abolishes DNA transcriptional activity when missing	
Q86YN6	UniProtKB	Region	122	148	.	.	.	Note=Disordered;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
Q86YN6	UniProtKB	Region	165	210	.	.	.	Note=Disordered;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
Q86YN6	UniProtKB	Region	237	278	.	.	.	Note=Disordered;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
Q86YN6	UniProtKB	Region	302	331	.	.	.	Note=Disordered;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
Q86YN6	UniProtKB	Region	369	463	.	.	.	Note=Disordered;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
Q86YN6	UniProtKB	Region	520	567	.	.	.	Note=Disordered;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
Q86YN6	UniProtKB	Region	601	623	.	.	.	Note=Disordered;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
Q86YN6	UniProtKB	Region	636	683	.	.	.	Note=Disordered;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
Q86YN6	UniProtKB	Region	717	758	.	.	.	Note=Disordered;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
Q86YN6	UniProtKB	Region	779	867	.	.	.	Note=Disordered;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
Q86YN6	UniProtKB	Motif	156	160	.	.	.	Note=LXXLL motif 1	
Q86YN6	UniProtKB	Motif	343	347	.	.	.	Note=LXXLL motif 2	
Q86YN6	UniProtKB	Motif	691	694	.	.	.	Note=HCFC1-binding-motif (HBM)	
Q86YN6	UniProtKB	Compositional bias	131	145	.	.	.	Note=Pro residues;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
Q86YN6	UniProtKB	Compositional bias	165	184	.	.	.	Note=Polar residues;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
Q86YN6	UniProtKB	Compositional bias	411	429	.	.	.	Note=Basic and acidic residues;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
Q86YN6	UniProtKB	Compositional bias	430	447	.	.	.	Note=Acidic residues;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
Q86YN6	UniProtKB	Compositional bias	653	667	.	.	.	Note=Basic and acidic residues;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
Q86YN6	UniProtKB	Compositional bias	734	758	.	.	.	Note=Basic and acidic residues;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
Q86YN6	UniProtKB	Compositional bias	789	803	.	.	.	Note=Polar residues;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
Q86YN6	UniProtKB	Compositional bias	804	826	.	.	.	Note=Acidic residues;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
Q86YN6	UniProtKB	Compositional bias	831	867	.	.	.	Note=Polar residues;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
Q86YN6	UniProtKB	Modified residue	384	384	.	.	.	Note=Phosphoserine;Ontology_term=ECO:0007744;evidence=ECO:0007744|PubMed:23186163;Dbxref=PMID:23186163	
Q86YN6	UniProtKB	Modified residue	524	524	.	.	.	Note=Phosphoserine;Ontology_term=ECO:0007744,ECO:0007744;evidence=ECO:0007744|PubMed:18669648,ECO:0007744|PubMed:23186163;Dbxref=PMID:18669648,PMID:23186163	
Q86YN6	UniProtKB	Modified residue	638	638	.	.	.	Note=Phosphoserine;Ontology_term=ECO:0007744;evidence=ECO:0007744|PubMed:23186163;Dbxref=PMID:23186163	
Q86YN6	UniProtKB	Alternative sequence	1	26	.	.	.	ID=VSP_019299;Note=In isoform 2 and isoform 4. MAGNDCGALLDEELSSFFLNYLADTQ->MGVYK;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:12678921;Dbxref=PMID:12678921	
Q86YN6	UniProtKB	Alternative sequence	1	26	.	.	.	ID=VSP_043374;Note=In isoform 6. MAGNDCGALLDEELSSFFLNYLADTQ->M;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:14702039;Dbxref=PMID:14702039	
Q86YN6	UniProtKB	Alternative sequence	156	194	.	.	.	ID=VSP_019300;Note=In isoform 5 and isoform 6. Missing;Ontology_term=ECO:0000303,ECO:0000303;evidence=ECO:0000303|PubMed:11854298,ECO:0000303|PubMed:14702039;Dbxref=PMID:11854298,PMID:14702039	
Q86YN6	UniProtKB	Alternative sequence	991	1023	.	.	.	ID=VSP_019301;Note=In isoform 3 and isoform 4. DSNSEEALPASGKSKYEAMDFDSLLKEAQQSLH->GKPLKPSHSLVRLKAWEAVPSLNKTQS;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:12678921;Dbxref=PMID:12678921	
Q86YN6	UniProtKB	Natural variant	203	203	.	.	.	ID=VAR_026698;Note=A->P;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:15863669;Dbxref=dbSNP:rs7732671,PMID:15863669	
Q86YN6	UniProtKB	Natural variant	265	265	.	.	.	ID=VAR_026699;Note=R->Q;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:12678921;Dbxref=dbSNP:rs45520937,PMID:12678921	
Q86YN6	UniProtKB	Natural variant	279	279	.	.	.	ID=VAR_026700;Note=V->I;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:15863669;Dbxref=dbSNP:rs17572019,PMID:15863669	
Q86YN6	UniProtKB	Natural variant	292	292	.	.	.	ID=VAR_026701;Note=R->S;Ontology_term=ECO:0000269,ECO:0000269;evidence=ECO:0000269|PubMed:15489334,ECO:0000269|PubMed:15863669;Dbxref=dbSNP:rs11959820,PMID:15489334,PMID:15863669	
Q86YN6	UniProtKB	Mutagenesis	92	96	.	.	.	Note=Reduces DNA transcriptional activity. LLAEL->AAAEA;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:11854298;Dbxref=PMID:11854298	
Q86YN6	UniProtKB	Mutagenesis	155	160	.	.	.	Note=Reduces interaction and activation of ESR1. Loss of interaction and activation of ESR1%3B when associated with 343-AREAA-347. LLQKLL->AAQKAA;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:11854298;Dbxref=PMID:11854298	
Q86YN6	UniProtKB	Mutagenesis	343	347	.	.	.	Note=Reduces interaction and activation of ESR1. Loss of interaction and activation of ESR1%3B when associated with 155-AAQKAA-160. LRELL->AREAA;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:11854298;Dbxref=PMID:11854298	
Q86YN6	UniProtKB	Sequence conflict	558	558	.	.	.	Note=E->G;Ontology_term=ECO:0000305;evidence=ECO:0000305	
Q86YN6	UniProtKB	Helix	155	162	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:3SP6	
Q86YN6	UniProtKB	Helix	1011	1021	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:6D0Y