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Protein

Protein FAM90A1

Gene

FAM90A1

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Protein FAM90A1
Gene namesi
Name:FAM90A1
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 12

Organism-specific databases

EuPathDBiHostDB:ENSG00000171847.10.
HGNCiHGNC:25526. FAM90A1.

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000171847.
PharmGKBiPA142671796.

Polymorphism and mutation databases

BioMutaiFAM90A1.
DMDMi269849691.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002995921 – 464Protein FAM90A1Add BLAST464

Proteomic databases

PaxDbiQ86YD7.
PeptideAtlasiQ86YD7.
PRIDEiQ86YD7.

PTM databases

iPTMnetiQ86YD7.
PhosphoSitePlusiQ86YD7.

Expressioni

Gene expression databases

BgeeiENSG00000171847.
CleanExiHS_FAM90A1.
ExpressionAtlasiQ86YD7. baseline and differential.
GenevisibleiQ86YD7. HS.

Interactioni

Binary interactionsi

Show more details

Protein-protein interaction databases

BioGridi120442. 49 interactors.
IntActiQ86YD7. 123 interactors.
STRINGi9606.ENSP00000307798.

Structurei

3D structure databases

ProteinModelPortaliQ86YD7.
SMRiQ86YD7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the FAM90 family.Curated

Phylogenomic databases

eggNOGiENOG410JA2C. Eukaryota.
ENOG4111A8B. LUCA.
GeneTreeiENSGT00530000063065.
HOGENOMiHOG000015373.
HOVERGENiHBG107893.
InParanoidiQ86YD7.
OMAiCDYLRVA.
OrthoDBiEOG091G0D9U.
PhylomeDBiQ86YD7.
TreeFamiTF338572.

Sequencei

Sequence statusi: Complete.

Q86YD7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MMARRDPKPG AKRLVRAQTL QKQRRAPVGP RAPPPDEEDP RLKCKNCEAF
60 70 80 90 100
GHTARSTRCP MKCWKAALVP PNFGEKEGKE NLKPWKPQVE ANPGPLNKDK
110 120 130 140 150
GEKEERPRPQ DPQRKALLHI FSRKPPEKPL PNQKGSTESS DYLRVASGPM
160 170 180 190 200
PVHTTSKRPR VDPVLSDRSA TEMSDRGSVL ASLSPLRKAS LSSSSSLGPK
210 220 230 240 250
ERQTGAAADI PQTAVRHQGP EPLLVVKPTH SSPAGGCREV PQAASKTHGL
260 270 280 290 300
LQAVSPQAQD KRPAVTSQPC PPAATHSLGL GSNLSFGPGA KRSAPAPIQA
310 320 330 340 350
CLNFPKKPRL GPFQIPESAI QGGELGAPEN LQPPPAATEL GPRTSPQTGT
360 370 380 390 400
RTPAQVLSGD RQPPHSRPCL PTAQACTMSH HPAASHDGAQ PLRVLFRRLE
410 420 430 440 450
NGRWSSSLLT APSFHSPEKP GAFLAQSPHV SEKSEGPCVR VPPSVLYEDL
460
QVPSSSEDSD SDLE
Length:464
Mass (Da):49,793
Last modified:November 24, 2009 - v3
Checksum:iD9E36FCEE5021250
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti254 – 255VS → AR in AAH42608 (PubMed:15489334).Curated2
Sequence conflicti344T → TV in BAA91593 (PubMed:14702039).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Natural variantiVAR_060293123R → G2 PublicationsCorresponds to variant dbSNP:rs9738115Ensembl.1
Natural variantiVAR_057778234A → E1 PublicationCorresponds to variant dbSNP:rs9668582Ensembl.1
Natural variantiVAR_060294334P → L1 PublicationCorresponds to variant dbSNP:rs17855656Ensembl.1
Natural variantiVAR_060154343R → S. Corresponds to variant dbSNP:rs9668475Ensembl.1
Natural variantiVAR_060295348T → I3 PublicationsCorresponds to variant dbSNP:rs9668474Ensembl.1
Natural variantiVAR_060155410T → A. Corresponds to variant dbSNP:rs11044098Ensembl.1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK001270 mRNA. Translation: BAA91593.1.
AC092111 Genomic DNA. No translation available.
CH471116 Genomic DNA. Translation: EAW88629.1.
CH471116 Genomic DNA. Translation: EAW88630.1.
BC042608 mRNA. Translation: AAH42608.1.
CCDSiCCDS31738.1.
RefSeqiNP_001306911.1. NM_001319982.1.
NP_060558.3. NM_018088.3.
XP_011519021.1. XM_011520719.1.
XP_016875036.1. XM_017019547.1.
UniGeneiHs.196086.

Genome annotation databases

EnsembliENST00000307435; ENSP00000307798; ENSG00000171847.
ENST00000538603; ENSP00000445418; ENSG00000171847.
GeneIDi55138.
KEGGihsa:55138.
UCSCiuc001quh.3. human.

Keywords - Coding sequence diversityi

Polymorphism

Similar proteinsi

Entry informationi

Entry nameiF90A1_HUMAN
AccessioniPrimary (citable) accession number: Q86YD7
Secondary accession number(s): D3DUU9, Q9NVZ6
Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 11, 2007
Last sequence update: November 24, 2009
Last modified: September 27, 2017
This is version 104 of the entry and version 3 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 12
    Human chromosome 12: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  5. SIMILARITY comments
    Index of protein domains and families