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Q86XI8

- CS068_HUMAN

UniProt

Q86XI8 - CS068_HUMAN

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Protein

Uncharacterized protein C19orf68

Gene
C19orf68
Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 2 out of 5 - Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  1. protein binding Source: IntAct

GO - Biological processi

  1. multicellular organismal development Source: InterPro
  2. ubiquitin-dependent protein catabolic process Source: InterPro
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized protein C19orf68
Gene namesi
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 19

Organism-specific databases

HGNCiHGNC:34495. C19orf68.

Subcellular locationi

GO - Cellular componenti

  1. nucleus Source: InterPro
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 627627Uncharacterized protein C19orf68PRO_0000322596Add
BLAST

Proteomic databases

MaxQBiQ86XI8.
PaxDbiQ86XI8.
PRIDEiQ86XI8.

PTM databases

PhosphoSiteiQ86XI8.

Expressioni

Gene expression databases

BgeeiQ86XI8.
CleanExiHS_C19orf68.
GenevestigatoriQ86XI8.

Organism-specific databases

HPAiHPA061028.

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
JUNBP172752EBI-2682158,EBI-748062

Protein-protein interaction databases

IntActiQ86XI8. 3 interactions.

Structurei

3D structure databases

ProteinModelPortaliQ86XI8.
SMRiQ86XI8. Positions 442-503, 538-616.

Family & Domainsi

Phylogenomic databases

eggNOGiNOG86879.
HOGENOMiHOG000112000.
HOVERGENiHBG107768.
InParanoidiQ86XI8.
OMAiNQISKQF.
OrthoDBiEOG70GMDX.
PhylomeDBiQ86XI8.
TreeFamiTF337793.

Family and domain databases

InterProiIPR004162. SINA_like.
[Graphical view]
PANTHERiPTHR10315. PTHR10315. 1 hit.

Sequencei

Sequence statusi: Complete.

Q86XI8-1 [UniParc]FASTAAdd to Basket

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MERPEPPPGT AAGQEEQELR ERAFFSWAEF SRFFDAWCQQ RLALFFVKSS    50
MHLARCRWAS APPLYTLIDV LKYSYVRLVC KDVRAPSRPA VGPPQPGCPA 100
FIIVKLSPLR DRLVVTECQL THSHPACPLE FAYYFRPGHL LANACLPVRT 150
TNKISKQFVA PADVRRLLSY CKGRDHGVLD ALHVLEGLFR TDPEAKVKLV 200
FVEDQAVVET VFFLTSRTRA LLRRFPRMLL VDRLPGLQGA LDLLAVLCVD 250
GSGRARQAAC CVARPGTPSL LRFALASLLQ SAPDVKGRVR CLTAGPEVAA 300
QLPAVRQLLP CARVQICRAQ GLETLFSKAQ ELGGAGREDP GLWSRLCRLA 350
GASSPAAYDE ALAELHAHGP AAFVDYFERN WEPRRDMWVR FRAFEAARDL 400
DACALVRGHR RRLLRRLSPS RGVAQCLRDL VAMQWADAAG EAVPEGPDGG 450
GPWLEDEPGR GAQGENERVR GLETGDWGGA PKEGSIWRGA QMEKEWARAL 500
ETRDWGGAQF EGEKGRALQI RDWRGGRLEN QKPRGLEGGV LRGSKLEKGH 550
LRGPEIRDWR GPQLEGEKDW GLEGYVWRGS QLEDQALRGL EGYTWRVAQL 600
EDRRSTTDLR GTQFDYERGK GESTEDR 627
Length:627
Mass (Da):70,073
Last modified:February 26, 2008 - v2
Checksum:i84D0F5AFC0478DBD
GO

Sequence cautioni

The sequence AAH43386.1 differs from that shown. Reason: Erroneous initiation.

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC011466 Genomic DNA. No translation available.
BC043386 mRNA. Translation: AAH43386.1. Different initiation.
RefSeqiNP_955373.3. NM_199341.3.
UniGeneiHs.664054.

Genome annotation databases

EnsembliENST00000328759; ENSP00000331363; ENSG00000185453.
GeneIDi374920.
KEGGihsa:374920.
UCSCiuc002pic.3. human.

Polymorphism databases

DMDMi189046910.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC011466 Genomic DNA. No translation available.
BC043386 mRNA. Translation: AAH43386.1 . Different initiation.
RefSeqi NP_955373.3. NM_199341.3.
UniGenei Hs.664054.

3D structure databases

ProteinModelPortali Q86XI8.
SMRi Q86XI8. Positions 442-503, 538-616.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

IntActi Q86XI8. 3 interactions.

PTM databases

PhosphoSitei Q86XI8.

Polymorphism databases

DMDMi 189046910.

Proteomic databases

MaxQBi Q86XI8.
PaxDbi Q86XI8.
PRIDEi Q86XI8.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000328759 ; ENSP00000331363 ; ENSG00000185453 .
GeneIDi 374920.
KEGGi hsa:374920.
UCSCi uc002pic.3. human.

Organism-specific databases

CTDi 374920.
GeneCardsi GC19P048673.
HGNCi HGNC:34495. C19orf68.
HPAi HPA061028.
neXtProti NX_Q86XI8.
GenAtlasi Search...

Phylogenomic databases

eggNOGi NOG86879.
HOGENOMi HOG000112000.
HOVERGENi HBG107768.
InParanoidi Q86XI8.
OMAi NQISKQF.
OrthoDBi EOG70GMDX.
PhylomeDBi Q86XI8.
TreeFami TF337793.

Miscellaneous databases

ChiTaRSi C19orf68. human.
GenomeRNAii 374920.

Gene expression databases

Bgeei Q86XI8.
CleanExi HS_C19orf68.
Genevestigatori Q86XI8.

Family and domain databases

InterProi IPR004162. SINA_like.
[Graphical view ]
PANTHERi PTHR10315. PTHR10315. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "The DNA sequence and biology of human chromosome 19."
    Grimwood J., Gordon L.A., Olsen A.S., Terry A., Schmutz J., Lamerdin J.E., Hellsten U., Goodstein D., Couronne O., Tran-Gyamfi M., Aerts A., Altherr M., Ashworth L., Bajorek E., Black S., Branscomb E., Caenepeel S., Carrano A.V.
    , Caoile C., Chan Y.M., Christensen M., Cleland C.A., Copeland A., Dalin E., Dehal P., Denys M., Detter J.C., Escobar J., Flowers D., Fotopulos D., Garcia C., Georgescu A.M., Glavina T., Gomez M., Gonzales E., Groza M., Hammon N., Hawkins T., Haydu L., Ho I., Huang W., Israni S., Jett J., Kadner K., Kimball H., Kobayashi A., Larionov V., Leem S.-H., Lopez F., Lou Y., Lowry S., Malfatti S., Martinez D., McCready P.M., Medina C., Morgan J., Nelson K., Nolan M., Ovcharenko I., Pitluck S., Pollard M., Popkie A.P., Predki P., Quan G., Ramirez L., Rash S., Retterer J., Rodriguez A., Rogers S., Salamov A., Salazar A., She X., Smith D., Slezak T., Solovyev V., Thayer N., Tice H., Tsai M., Ustaszewska A., Vo N., Wagner M., Wheeler J., Wu K., Xie G., Yang J., Dubchak I., Furey T.S., DeJong P., Dickson M., Gordon D., Eichler E.E., Pennacchio L.A., Richardson P., Stubbs L., Rokhsar D.S., Myers R.M., Rubin E.M., Lucas S.M.
    Nature 428:529-535(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Eye.

Entry informationi

Entry nameiCS068_HUMAN
AccessioniPrimary (citable) accession number: Q86XI8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 26, 2008
Last sequence update: February 26, 2008
Last modified: June 11, 2014
This is version 67 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 19
    Human chromosome 19: entries, gene names and cross-references to MIM

External Data

Dasty 3

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