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Q86XI8

- CS068_HUMAN

UniProt

Q86XI8 - CS068_HUMAN

Protein

Uncharacterized protein C19orf68

Gene

C19orf68

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 68 (01 Oct 2014)
      Sequence version 2 (26 Feb 2008)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. protein binding Source: IntAct

    GO - Biological processi

    1. multicellular organismal development Source: InterPro
    2. ubiquitin-dependent protein catabolic process Source: InterPro

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Uncharacterized protein C19orf68
    Gene namesi
    OrganismiHomo sapiens (Human)
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 19

    Organism-specific databases

    HGNCiHGNC:34495. C19orf68.

    Subcellular locationi

    GO - Cellular componenti

    1. nucleus Source: InterPro

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 627627Uncharacterized protein C19orf68PRO_0000322596Add
    BLAST

    Proteomic databases

    MaxQBiQ86XI8.
    PaxDbiQ86XI8.
    PRIDEiQ86XI8.

    PTM databases

    PhosphoSiteiQ86XI8.

    Expressioni

    Gene expression databases

    BgeeiQ86XI8.
    CleanExiHS_C19orf68.
    GenevestigatoriQ86XI8.

    Organism-specific databases

    HPAiHPA061028.

    Interactioni

    Binary interactionsi

    WithEntry#Exp.IntActNotes
    JUNBP172752EBI-2682158,EBI-748062

    Protein-protein interaction databases

    IntActiQ86XI8. 3 interactions.

    Structurei

    3D structure databases

    ProteinModelPortaliQ86XI8.
    SMRiQ86XI8. Positions 442-503, 538-616.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Phylogenomic databases

    eggNOGiNOG86879.
    HOGENOMiHOG000112000.
    HOVERGENiHBG107768.
    InParanoidiQ86XI8.
    OMAiNQISKQF.
    OrthoDBiEOG70GMDX.
    PhylomeDBiQ86XI8.
    TreeFamiTF337793.

    Family and domain databases

    InterProiIPR004162. SINA_like.
    [Graphical view]
    PANTHERiPTHR10315. PTHR10315. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q86XI8-1 [UniParc]FASTAAdd to Basket

    « Hide

    MERPEPPPGT AAGQEEQELR ERAFFSWAEF SRFFDAWCQQ RLALFFVKSS    50
    MHLARCRWAS APPLYTLIDV LKYSYVRLVC KDVRAPSRPA VGPPQPGCPA 100
    FIIVKLSPLR DRLVVTECQL THSHPACPLE FAYYFRPGHL LANACLPVRT 150
    TNKISKQFVA PADVRRLLSY CKGRDHGVLD ALHVLEGLFR TDPEAKVKLV 200
    FVEDQAVVET VFFLTSRTRA LLRRFPRMLL VDRLPGLQGA LDLLAVLCVD 250
    GSGRARQAAC CVARPGTPSL LRFALASLLQ SAPDVKGRVR CLTAGPEVAA 300
    QLPAVRQLLP CARVQICRAQ GLETLFSKAQ ELGGAGREDP GLWSRLCRLA 350
    GASSPAAYDE ALAELHAHGP AAFVDYFERN WEPRRDMWVR FRAFEAARDL 400
    DACALVRGHR RRLLRRLSPS RGVAQCLRDL VAMQWADAAG EAVPEGPDGG 450
    GPWLEDEPGR GAQGENERVR GLETGDWGGA PKEGSIWRGA QMEKEWARAL 500
    ETRDWGGAQF EGEKGRALQI RDWRGGRLEN QKPRGLEGGV LRGSKLEKGH 550
    LRGPEIRDWR GPQLEGEKDW GLEGYVWRGS QLEDQALRGL EGYTWRVAQL 600
    EDRRSTTDLR GTQFDYERGK GESTEDR 627
    Length:627
    Mass (Da):70,073
    Last modified:February 26, 2008 - v2
    Checksum:i84D0F5AFC0478DBD
    GO

    Sequence cautioni

    The sequence AAH43386.1 differs from that shown. Reason: Erroneous initiation.

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC011466 Genomic DNA. No translation available.
    BC043386 mRNA. Translation: AAH43386.1. Different initiation.
    RefSeqiNP_955373.3. NM_199341.3.
    UniGeneiHs.664054.

    Genome annotation databases

    EnsembliENST00000328759; ENSP00000331363; ENSG00000185453.
    GeneIDi374920.
    KEGGihsa:374920.
    UCSCiuc002pic.3. human.

    Polymorphism databases

    DMDMi189046910.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC011466 Genomic DNA. No translation available.
    BC043386 mRNA. Translation: AAH43386.1 . Different initiation.
    RefSeqi NP_955373.3. NM_199341.3.
    UniGenei Hs.664054.

    3D structure databases

    ProteinModelPortali Q86XI8.
    SMRi Q86XI8. Positions 442-503, 538-616.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    IntActi Q86XI8. 3 interactions.

    PTM databases

    PhosphoSitei Q86XI8.

    Polymorphism databases

    DMDMi 189046910.

    Proteomic databases

    MaxQBi Q86XI8.
    PaxDbi Q86XI8.
    PRIDEi Q86XI8.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000328759 ; ENSP00000331363 ; ENSG00000185453 .
    GeneIDi 374920.
    KEGGi hsa:374920.
    UCSCi uc002pic.3. human.

    Organism-specific databases

    CTDi 374920.
    GeneCardsi GC19P048673.
    HGNCi HGNC:34495. C19orf68.
    HPAi HPA061028.
    neXtProti NX_Q86XI8.
    GenAtlasi Search...

    Phylogenomic databases

    eggNOGi NOG86879.
    HOGENOMi HOG000112000.
    HOVERGENi HBG107768.
    InParanoidi Q86XI8.
    OMAi NQISKQF.
    OrthoDBi EOG70GMDX.
    PhylomeDBi Q86XI8.
    TreeFami TF337793.

    Miscellaneous databases

    ChiTaRSi C19orf68. human.
    GenomeRNAii 374920.

    Gene expression databases

    Bgeei Q86XI8.
    CleanExi HS_C19orf68.
    Genevestigatori Q86XI8.

    Family and domain databases

    InterProi IPR004162. SINA_like.
    [Graphical view ]
    PANTHERi PTHR10315. PTHR10315. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "The DNA sequence and biology of human chromosome 19."
      Grimwood J., Gordon L.A., Olsen A.S., Terry A., Schmutz J., Lamerdin J.E., Hellsten U., Goodstein D., Couronne O., Tran-Gyamfi M., Aerts A., Altherr M., Ashworth L., Bajorek E., Black S., Branscomb E., Caenepeel S., Carrano A.V.
      , Caoile C., Chan Y.M., Christensen M., Cleland C.A., Copeland A., Dalin E., Dehal P., Denys M., Detter J.C., Escobar J., Flowers D., Fotopulos D., Garcia C., Georgescu A.M., Glavina T., Gomez M., Gonzales E., Groza M., Hammon N., Hawkins T., Haydu L., Ho I., Huang W., Israni S., Jett J., Kadner K., Kimball H., Kobayashi A., Larionov V., Leem S.-H., Lopez F., Lou Y., Lowry S., Malfatti S., Martinez D., McCready P.M., Medina C., Morgan J., Nelson K., Nolan M., Ovcharenko I., Pitluck S., Pollard M., Popkie A.P., Predki P., Quan G., Ramirez L., Rash S., Retterer J., Rodriguez A., Rogers S., Salamov A., Salazar A., She X., Smith D., Slezak T., Solovyev V., Thayer N., Tice H., Tsai M., Ustaszewska A., Vo N., Wagner M., Wheeler J., Wu K., Xie G., Yang J., Dubchak I., Furey T.S., DeJong P., Dickson M., Gordon D., Eichler E.E., Pennacchio L.A., Richardson P., Stubbs L., Rokhsar D.S., Myers R.M., Rubin E.M., Lucas S.M.
      Nature 428:529-535(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Tissue: Eye.

    Entry informationi

    Entry nameiCS068_HUMAN
    AccessioniPrimary (citable) accession number: Q86XI8
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: February 26, 2008
    Last sequence update: February 26, 2008
    Last modified: October 1, 2014
    This is version 68 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Human chromosome 19
      Human chromosome 19: entries, gene names and cross-references to MIM

    External Data

    Dasty 3