Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

PDXDC1 protein

Gene

PDXDC1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Cofactori

pyridoxal 5'-phosphateUniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotation

Keywords - Ligandi

Pyridoxal phosphateUniRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
PDXDC1 proteinImported
Submitted name:
Pyridoxal-dependent decarboxylase domain-containing protein 1Imported
Gene namesi
Name:PDXDC1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 16

Organism-specific databases

HGNCiHGNC:28995. PDXDC1.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000179889.
ENSG00000276709.

Expressioni

Gene expression databases

BgeeiENSG00000179889.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000379691.

Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili13 – 37Sequence analysisAdd BLAST25

Sequence similaritiesi

Belongs to the group II decarboxylase family.UniRule annotation

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG0630. Eukaryota.
ENOG410XYFU. LUCA.
GeneTreeiENSGT00390000009628.
HOVERGENiHBG062459.
OMAiMHGDESE.
OrthoDBiEOG091G066W.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
3.90.1150.10. 1 hit.
InterProiIPR002129. PyrdxlP-dep_de-COase.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
[Graphical view]
PfamiPF00282. Pyridoxal_deC. 1 hit.
[Graphical view]
SUPFAMiSSF53383. SSF53383. 2 hits.

Sequencei

Sequence statusi: Complete.

Q86XE2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDASLEKIAD PTLAEMGKNL KEAVKMLEDS QRRTEEENGK KLISGDIPGP
60 70 80 90 100
LQGSGQDMVS ILQLVQNLMH GDEDEEPQSP RIQNIGEQGH MALLGHSLGA
110 120 130 140 150
YISTLDKEKL RKLTTRILSD TTLWLCRIFR YENGCAYFHE EEREGLAKIC
160 170 180 190 200
RLAIHSRYED FVVDGFNVLY NKKPVIYLSA AARPGLGQYL CNQLGLPFPC
210 220 230 240 250
LCRVPCNTVF GSQHQMDVAF LEKLIKDDIE RGRLPLLLVA NAGTAAVGHT
260 270 280 290 300
DKIGRLKELC EQYGIWLHVE GVNLATLALG YVSSSVLAAA KCDSMTMTPG
310 320 330 340 350
PWLGLPAVPA VTLYKHDDPA LTLVAGLTSN KPTDKLRALP LWLSLQYLGL
360 370 380 390 400
DGFVERIKHA CQLSQRLQES LKKVNYIKIL VEDELSSPVV VFRFFQELPG
410 420 430 440 450
SDPVFKAVPV PNMTPSGVGR ERHSCDALNR WLGEQLKQLV PASGLTVMDL
460 470 480 490
EAEGTCLRFS PLMTAAGWSH CGTTTRYDCV RSRLTTRLPG STGEQAPP
Length:498
Mass (Da):54,982
Last modified:August 30, 2005 - v2
Checksum:i84A47B0228909E0A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC138932 Genomic DNA. No translation available.
AC139256 Genomic DNA. No translation available.
AC245049 Genomic DNA. No translation available.
BC045554 mRNA. Translation: AAH45554.2.
RefSeqiNP_001272378.1. NM_001285449.1.
XP_016855156.1. XM_016999667.1.
XP_016885698.1. XM_017030209.1.
UniGeneiHs.370781.

Genome annotation databases

EnsembliENST00000535621; ENSP00000437835; ENSG00000179889.
ENST00000614060; ENSP00000483785; ENSG00000276709.
GeneIDi102724985.
23042.
UCSCiuc002ddc.5. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC138932 Genomic DNA. No translation available.
AC139256 Genomic DNA. No translation available.
AC245049 Genomic DNA. No translation available.
BC045554 mRNA. Translation: AAH45554.2.
RefSeqiNP_001272378.1. NM_001285449.1.
XP_016855156.1. XM_016999667.1.
XP_016885698.1. XM_017030209.1.
UniGeneiHs.370781.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000379691.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000535621; ENSP00000437835; ENSG00000179889.
ENST00000614060; ENSP00000483785; ENSG00000276709.
GeneIDi102724985.
23042.
UCSCiuc002ddc.5. human.

Organism-specific databases

CTDi23042.
HGNCiHGNC:28995. PDXDC1.
OpenTargetsiENSG00000179889.
ENSG00000276709.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG0630. Eukaryota.
ENOG410XYFU. LUCA.
GeneTreeiENSGT00390000009628.
HOVERGENiHBG062459.
OMAiMHGDESE.
OrthoDBiEOG091G066W.

Miscellaneous databases

ChiTaRSiPDXDC1. human.
GenomeRNAii23042.

Gene expression databases

BgeeiENSG00000179889.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
3.90.1150.10. 1 hit.
InterProiIPR002129. PyrdxlP-dep_de-COase.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
[Graphical view]
PfamiPF00282. Pyridoxal_deC. 1 hit.
[Graphical view]
SUPFAMiSSF53383. SSF53383. 2 hits.
ProtoNetiSearch...

Entry informationi

Entry nameiQ86XE2_HUMAN
AccessioniPrimary (citable) accession number: Q86XE2
Entry historyi
Integrated into UniProtKB/TrEMBL: June 1, 2003
Last sequence update: August 30, 2005
Last modified: November 30, 2016
This is version 104 of the entry and version 2 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.