Q86XA9 (HTR5A_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
HEAT repeat-containing protein 5A

Gene names

Name:	HEATR5A
Synonyms:	C14orf125, KIAA1316

Organism

Homo sapiens (Human) [Reference proteome]

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	2040 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Sequence similarities	Belongs to the HEATR5 family. Contains 2 HEAT repeats.
Sequence caution	The sequence BAA91098.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.

Ontologies

Keywords
Coding sequence diversity	Alternative splicing
Domain	Repeat
PTM	Phosphoprotein
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
None. [Check GOA]

Alternative products

This entry describes 3 isoforms produced by alternative splicing. [Align] [Select]

Isoform 1 (identifier: Q86XA9-1)

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

Isoform 2 (identifier: Q86XA9-2)

The sequence of this isoform differs from the canonical sequence as follows:
     1741-1815: Missing.

Note: No experimental confirmation available.

Isoform 3 (identifier: Q86XA9-3)

The sequence of this isoform differs from the canonical sequence as follows:
     114-2040: Missing.

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 2040	2040	HEAT repeat-containing protein 5A		PRO_0000311990
Regions
	Repeat	846 – 883	38	HEAT 1
	Repeat	1079 – 1116	38	HEAT 2
Amino acid modifications
	Modified residue	1110	1	Phosphoserine Ref.7
	Modified residue	1115	1	Phosphothreonine Ref.7
	Modified residue	1647	1	Phosphoserine Ref.7
Natural variations
	Alternative sequence	114 – 2040	1927	Missing in isoform 3.		VSP_029685
	Alternative sequence	1741 – 1815	75	Missing in isoform 2.		VSP_029686
Experimental info
	Sequence conflict	429	1	L → P in CAH18282. Ref.4
	Sequence conflict	880	1	V → M in AAH45764. Ref.3
	Sequence conflict	880	1	V → M in CAH18282. Ref.4
	Sequence conflict	880	1	V → M in BAA92554. Ref.5
	Sequence conflict	1199	1	S → P in BAA91098. Ref.6
	Sequence conflict	1257	1	N → T in AAH63867. Ref.3
	Sequence conflict	1525	1	R → T in CAH18282. Ref.4

Sequences

	Sequence		Length	Mass (Da)
	Isoform 1 [UniParc]. Last modified December 4, 2007. Version 2. Checksum: E6598AA06A7D51DB	FASTA	2,040	222,004
	10 20 30 40 50 60 MELAHSLLLN EEAYNQLGEV QKAEFIFEWL RYLEKLLLAT SRNDVREKQK TLVEQLLSLL 70 80 90 100 110 120 NSSPGPPTRK LLAKNLAILY SIGDTFSVHE AIDKCNDLIR SKDDSPSYLP TKLAAVVCLG 130 140 150 160 170 180 SLYKKLGRIL GNTFTDTVGN ILKAMKSAES QGRYEIMLSL QNILNGLGAA AAPCHRDVYK 190 200 210 220 230 240 AARSCLTDRS MAVRCAAAKN EAIFMWSTDL DSVATLCFKS FEGSNYDVRI SVSKLLGIIL 250 260 270 280 290 300 AKAVISKHPG TAASRQSIRR VSLEEVLELL GTGFLRGSSG FLRASGDMLK GTSSVSRDVR 310 320 330 340 350 360 VGVTQAYVVF VSTLGGAWLE KNFAAFFSHI LSLASPSHPK ATQTQIDAVC CRRCVSFILR 370 380 390 400 410 420 TTIGGLLGEK AQLAAVKDIC QAIWKLKKVM DAVMSDGNLE TRLGSTDVAA SQHMLVCALQ 430 440 450 460 470 480 ELGNLIHNLG TTAAPLLQDS STGLLDSILS VILHPSISVR LAAAWCLHCI AVALPSYLTP 490 500 510 520 530 540 LLDRCLERLT GHKSSPEAVT GFSFAVAALL GAVKHCPLGI PHGKGKIIMT LAEDLLCSAA 550 560 570 580 590 600 QNSRLSAQRT QAGWLLISAL MTLGPAVVSH HLARVLLLWK CVFPASPKDL ETEKSRGDSF 610 620 630 640 650 660 TWQVTLEGRA GALCAIKSFV SHCGDLLTEE VTQRLLPPLP CAVDLLTQLS SILKMYGSPL 670 680 690 700 710 720 KTPSVVYRQR LYELLILLPP ETYEGNLCAI LRELAADLTA PDIQVAASTF LLPPLCHQDD 730 740 750 760 770 780 LLILSPFLQE TDHRFIEEQL LLGNGVACGS LEYDPYSIYE KDVEGDSVPK PLPPALSVIS 790 800 810 820 830 840 SASKLFGVVC AHVGETQRLL ILEQLLDSIK HTKGARQQVV QLHVVSSVSS FLKYVAGSKG 850 860 870 880 890 900 CLGPEEMKRF ALTLVMGALE SPNPLLRCAA AESWARLAQV VDDGAFTAGL AQVSFDKLKS 910 920 930 940 950 960 ARDVVTRTGH SLALGSLHRY LGGISSSQHL NSCIGILYTL AQDSTSPDVQ TWALHSLSLI 970 980 990 1000 1010 1020 IDSAGPLYYV HVEPTLSLII MLLLNVPPTH AEVHQSLGRC LNALITTLGP ELQGNSTSIS 1030 1040 1050 1060 1070 1080 TLRTSCLLGC AVMQDNPDCL VQAQAISCLQ QLHMFAPRHV NLSSLVSCLC VNLCSPYLLL 1090 1100 1110 1120 1130 1140 RRAVLACLRQ LVQREAAEVS EHAVMLAKDS REELTPDANI REVGLEGALL ILLDKETDER 1150 1160 1170 1180 1190 1200 LCHDIKETLN YMLTSMAVEK LSLWLKLCKD VLAASADFTA VTCVDTMQEE EGDKGDDASV 1210 1220 1230 1240 1250 1260 LTTRRDEKSH PFTNPRWATR VFAAECVCRI INQCENANSA HFDIALAQEM KKRDSRNDFL 1270 1280 1290 1300 1310 1320 VLHLADLIRM AFMAATDHSD QLRLSGLEML LVVIRRFATV PEPEFPGHVI LEQYQANVGA 1330 1340 1350 1360 1370 1380 ALRPAFTSET PPDVTAKACQ VCSAWIASGV VSDLNDLRRV HQLLVSSLTK IQAGKEALSH 1390 1400 1410 1420 1430 1440 LYNESASTME ILAVLKAWAE VYIIAVQRHK NHRQPLKTTT CLEDGIRNGS CSSDGLLDLV 1450 1460 1470 1480 1490 1500 YADLGTLSRL WLAALQDFAL LTLPSEFASQ LPAEGGAFYT AETSENAKLH YYNSWALILH 1510 1520 1530 1540 1550 1560 ATALWLTSTG FVVADPDEGA SNLSRPVTPT SMCQGSSSGA TIKSPEDVYT DRFHLILGIS 1570 1580 1590 1600 1610 1620 VEFLCSLRSD ATMESITACL HALQALLDVP WPRSKIGSDQ DLGIELLNVL HRVILTRESP 1630 1640 1650 1660 1670 1680 SIQLASLEVV RQIICAAQEH VKEKRRSAEV DDGAAEKETL PEFGEGKDTG GLVPGKSLVF 1690 1700 1710 1720 1730 1740 ATLELCVCIL VRQLPELNPK LTGSPGVKAT KPQILLEDGS RLVSAALVIL SELPAVCSPE 1750 1760 1770 1780 1790 1800 GSISILPTIL YLTIGVLRET AVKLPGGQLS STVAASLQAL KGILSSPMAR AEKSRTAWTD 1810 1820 1830 1840 1850 1860 LLRSALTTIL DCWDPVDETH QELDEVSLLT AITVFILSTS PEVTTIPCLQ KRCIDKFKAT 1870 1880 1890 1900 1910 1920 LEIKDPVVQI KTYQLLHSIF QYPNPAVSYP YIYSLASCIM EKLQEIDKRK PENTAELEIF 1930 1940 1950 1960 1970 1980 QEGIKVLETL VTVAEEHHRA QLVACLLPIL ISFLLDENSL GSATSIMRNL HDFALQNLMQ 1990 2000 2010 2020 2030 2040 IGPQYSSVFK SLVASSPALK ARLEAAIKGN QESVKVKIPT SKYTKSPGKN SSIQLKTSFL
	Isoform 2 [UniParc]. Checksum: E4589DBD3C413E33	FASTA	1,965	214,083
	10 20 30 40 50 60 MELAHSLLLN EEAYNQLGEV QKAEFIFEWL RYLEKLLLAT SRNDVREKQK TLVEQLLSLL 70 80 90 100 110 120 NSSPGPPTRK LLAKNLAILY SIGDTFSVHE AIDKCNDLIR SKDDSPSYLP TKLAAVVCLG 130 140 150 160 170 180 SLYKKLGRIL GNTFTDTVGN ILKAMKSAES QGRYEIMLSL QNILNGLGAA AAPCHRDVYK 190 200 210 220 230 240 AARSCLTDRS MAVRCAAAKN EAIFMWSTDL DSVATLCFKS FEGSNYDVRI SVSKLLGIIL 250 260 270 280 290 300 AKAVISKHPG TAASRQSIRR VSLEEVLELL GTGFLRGSSG FLRASGDMLK GTSSVSRDVR 310 320 330 340 350 360 VGVTQAYVVF VSTLGGAWLE KNFAAFFSHI LSLASPSHPK ATQTQIDAVC CRRCVSFILR 370 380 390 400 410 420 TTIGGLLGEK AQLAAVKDIC QAIWKLKKVM DAVMSDGNLE TRLGSTDVAA SQHMLVCALQ 430 440 450 460 470 480 ELGNLIHNLG TTAAPLLQDS STGLLDSILS VILHPSISVR LAAAWCLHCI AVALPSYLTP 490 500 510 520 530 540 LLDRCLERLT GHKSSPEAVT GFSFAVAALL GAVKHCPLGI PHGKGKIIMT LAEDLLCSAA 550 560 570 580 590 600 QNSRLSAQRT QAGWLLISAL MTLGPAVVSH HLARVLLLWK CVFPASPKDL ETEKSRGDSF 610 620 630 640 650 660 TWQVTLEGRA GALCAIKSFV SHCGDLLTEE VTQRLLPPLP CAVDLLTQLS SILKMYGSPL 670 680 690 700 710 720 KTPSVVYRQR LYELLILLPP ETYEGNLCAI LRELAADLTA PDIQVAASTF LLPPLCHQDD 730 740 750 760 770 780 LLILSPFLQE TDHRFIEEQL LLGNGVACGS LEYDPYSIYE KDVEGDSVPK PLPPALSVIS 790 800 810 820 830 840 SASKLFGVVC AHVGETQRLL ILEQLLDSIK HTKGARQQVV QLHVVSSVSS FLKYVAGSKG 850 860 870 880 890 900 CLGPEEMKRF ALTLVMGALE SPNPLLRCAA AESWARLAQV VDDGAFTAGL AQVSFDKLKS 910 920 930 940 950 960 ARDVVTRTGH SLALGSLHRY LGGISSSQHL NSCIGILYTL AQDSTSPDVQ TWALHSLSLI 970 980 990 1000 1010 1020 IDSAGPLYYV HVEPTLSLII MLLLNVPPTH AEVHQSLGRC LNALITTLGP ELQGNSTSIS 1030 1040 1050 1060 1070 1080 TLRTSCLLGC AVMQDNPDCL VQAQAISCLQ QLHMFAPRHV NLSSLVSCLC VNLCSPYLLL 1090 1100 1110 1120 1130 1140 RRAVLACLRQ LVQREAAEVS EHAVMLAKDS REELTPDANI REVGLEGALL ILLDKETDER 1150 1160 1170 1180 1190 1200 LCHDIKETLN YMLTSMAVEK LSLWLKLCKD VLAASADFTA VTCVDTMQEE EGDKGDDASV 1210 1220 1230 1240 1250 1260 LTTRRDEKSH PFTNPRWATR VFAAECVCRI INQCENANSA HFDIALAQEM KKRDSRNDFL 1270 1280 1290 1300 1310 1320 VLHLADLIRM AFMAATDHSD QLRLSGLEML LVVIRRFATV PEPEFPGHVI LEQYQANVGA 1330 1340 1350 1360 1370 1380 ALRPAFTSET PPDVTAKACQ VCSAWIASGV VSDLNDLRRV HQLLVSSLTK IQAGKEALSH 1390 1400 1410 1420 1430 1440 LYNESASTME ILAVLKAWAE VYIIAVQRHK NHRQPLKTTT CLEDGIRNGS CSSDGLLDLV 1450 1460 1470 1480 1490 1500 YADLGTLSRL WLAALQDFAL LTLPSEFASQ LPAEGGAFYT AETSENAKLH YYNSWALILH 1510 1520 1530 1540 1550 1560 ATALWLTSTG FVVADPDEGA SNLSRPVTPT SMCQGSSSGA TIKSPEDVYT DRFHLILGIS 1570 1580 1590 1600 1610 1620 VEFLCSLRSD ATMESITACL HALQALLDVP WPRSKIGSDQ DLGIELLNVL HRVILTRESP 1630 1640 1650 1660 1670 1680 SIQLASLEVV RQIICAAQEH VKEKRRSAEV DDGAAEKETL PEFGEGKDTG GLVPGKSLVF 1690 1700 1710 1720 1730 1740 ATLELCVCIL VRQLPELNPK LTGSPGVKAT KPQILLEDGS RLVSAALVIL SELPAVCSPE 1750 1760 1770 1780 1790 1800 VDETHQELDE VSLLTAITVF ILSTSPEVTT IPCLQKRCID KFKATLEIKD PVVQIKTYQL 1810 1820 1830 1840 1850 1860 LHSIFQYPNP AVSYPYIYSL ASCIMEKLQE IDKRKPENTA ELEIFQEGIK VLETLVTVAE 1870 1880 1890 1900 1910 1920 EHHRAQLVAC LLPILISFLL DENSLGSATS IMRNLHDFAL QNLMQIGPQY SSVFKSLVAS 1930 1940 1950 1960 SPALKARLEA AIKGNQESVK VKIPTSKYTK SPGKNSSIQL KTSFL
	Isoform 3 [UniParc]. Checksum: D2F13A11E214CFD3	FASTA	113	12,903
	10 20 30 40 50 60 MELAHSLLLN EEAYNQLGEV QKAEFIFEWL RYLEKLLLAT SRNDVREKQK TLVEQLLSLL 70 80 90 100 110 NSSPGPPTRK LLAKNLAILY SIGDTFSVHE AIDKCNDLIR SKDDSPSYLP TKL

References

[1]	"The DNA sequence and analysis of human chromosome 14." Heilig R., Eckenberg R., Petit J.-L., Fonknechten N., Da Silva C., Cattolico L., Levy M., Barbe V., De Berardinis V., Ureta-Vidal A., Pelletier E., Vico V., Anthouard V., Rowen L., Madan A., Qin S., Sun H., Du H. , Pepin K., Artiguenave F., Robert C., Cruaud C., Bruels T., Jaillon O., Friedlander L., Samson G., Brottier P., Cure S., Segurens B., Aniere F., Samain S., Crespeau H., Abbasi N., Aiach N., Boscus D., Dickhoff R., Dors M., Dubois I., Friedman C., Gouyvenoux M., James R., Madan A., Mairey-Estrada B., Mangenot S., Martins N., Menard M., Oztas S., Ratcliffe A., Shaffer T., Trask B., Vacherie B., Bellemere C., Belser C., Besnard-Gonnet M., Bartol-Mavel D., Boutard M., Briez-Silla S., Combette S., Dufosse-Laurent V., Ferron C., Lechaplais C., Louesse C., Muselet D., Magdelenat G., Pateau E., Petit E., Sirvain-Trukniewicz P., Trybou A., Vega-Czarny N., Bataille E., Bluet E., Bordelais I., Dubois M., Dumont C., Guerin T., Haffray S., Hammadi R., Muanga J., Pellouin V., Robert D., Wunderle E., Gauguet G., Roy A., Sainte-Marthe L., Verdier J., Verdier-Discala C., Hillier L.W., Fulton L., McPherson J., Matsuda F., Wilson R., Scarpelli C., Gyapay G., Wincker P., Saurin W., Quetier F., Waterston R., Hood L., Weissenbach J. Nature 421:601-607(2003) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[2]	Mural R.J., Istrail S., Sutton G.G., Florea L., Halpern A.L., Mobarry C.M., Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J., Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S., Turner R. , Yooseph S., Lu F., Nusskern D.R., Shue B.C., Zheng X.H., Zhong F., Delcher A.L., Huson D.H., Kravitz S.A., Mouchard L., Reinert K., Remington K.A., Clark A.G., Waterman M.S., Eichler E.E., Adams M.D., Hunkapiller M.W., Myers E.W., Venter J.C. Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[3]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 3), NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 263-2040 (ISOFORM 1). Tissue: PNS and Uterus.
[4]	"The full-ORF clone resource of the German cDNA consortium." Bechtel S., Rosenfelder H., Duda A., Schmidt C.P., Ernst U., Wellenreuther R., Mehrle A., Schuster C., Bahr A., Bloecker H., Heubner D., Hoerlein A., Michel G., Wedler H., Koehrer K., Ottenwaelder B., Poustka A., Wiemann S., Schupp I. BMC Genomics 8:399-399(2007) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 368-2040 (ISOFORM 2). Tissue: Amygdala and Testis.
[5]	"Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro." Nagase T., Kikuno R., Ishikawa K., Hirosawa M., Ohara O. DNA Res. 7:65-73(2000) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 451-2040 (ISOFORM 1). Tissue: Brain.
[6]	"Complete sequencing and characterization of 21,243 full-length human cDNAs." Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S. , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S. Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1172-1758 (ISOFORM 1). Tissue: Hepatoma and Placenta.
[7]	"Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle." Daub H., Olsen J.V., Bairlein M., Gnad F., Oppermann F.S., Korner R., Greff Z., Keri G., Stemmann O., Mann M. Mol. Cell 31:438-448(2008) [PubMed] [Europe PMC] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1110; THR-1115 AND SER-1647, MASS SPECTROMETRY. Tissue: Cervix carcinoma.
[8]	"Initial characterization of the human central proteome." Burkard T.R., Planyavsky M., Kaupe I., Breitwieser F.P., Buerckstuemmer T., Bennett K.L., Superti-Furga G., Colinge J. BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract] Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].

Cross-references

Sequence databases
EMBL GenBank DDBJ	AL136418 Genomic DNA. No translation available. AL139353 Genomic DNA. No translation available. CH471078 Genomic DNA. Translation: EAW65949.1. BC045764 mRNA. Translation: AAH45764.1. BC062720 mRNA. Translation: AAH62720.1. BC063867 mRNA. Translation: AAH63867.1. AL117511 mRNA. Translation: CAB55971.1. CR749444 mRNA. Translation: CAH18282.1. AB037737 mRNA. Translation: BAA92554.1. AK000343 mRNA. Translation: BAA91098.1. Different initiation.
IPI	IPI00329192. IPI00876909. IPI01013086.
PIR	T17281.
RefSeq	NP_056288.2. NM_015473.3.
UniGene	Hs.370299.
3D structure databases
ProteinModelPortal	Q86XA9.
ModBase	Search...
PTM databases
PhosphoSite	Q86XA9.
Polymorphism databases
DMDM	162416245.
Proteomic databases
PaxDb	Q86XA9.
PRIDE	Q86XA9.
Protocols and materials databases
DNASU	25938.
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENST00000382464; ENSP00000371903; ENSG00000129493. ENST00000389961; ENSP00000374611; ENSG00000129493. ENST00000439348; ENSP00000405407; ENSG00000129493.
GeneID	25938.
KEGG	hsa:25938.
UCSC	uc001wrh.3. human. uc010ami.3. human.
Organism-specific databases
CTD	25938.
GeneCards	GC14M031760.
H-InvDB	HIX0011581.
HGNC	HGNC:20276. HEATR5A.
HPA	HPA049539.
neXtProt	NX_Q86XA9.
PharmGKB	PA162390632.
HUGE	Search...
GenAtlas	Search...
Phylogenomic databases
eggNOG	NOG289817.
HOVERGEN	HBG056837.
InParanoid	Q86XA9.
Gene expression databases
ArrayExpress	Q86XA9.
Bgee	Q86XA9.
CleanEx	HS_HEATR5A.
Genevestigator	Q86XA9.
Family and domain databases
Gene3D	1.25.10.10. 4 hits.
InterPro	IPR011989. ARM-like. IPR016024. ARM-type_fold. [Graphical view]
SUPFAM	SSF48371. ARM-type_fold. 2 hits.
PROSITE	PS50077. HEAT_REPEAT. False negative. [Graphical view]
ProtoNet	Search...
Other
ChiTaRS	HEATR5A. human.
GenomeRNAi	25938.
NextBio	47498.

Entry information

Entry name

HTR5A_HUMAN

Accession

Primary (citable) accession number: Q86XA9
Secondary accession number(s): Q68DD8 , Q6P3S5, Q6P5R9, Q9H8D7, Q9NXB7, Q9P2N0, Q9UFQ3

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 4, 2007
Last sequence update:	December 4, 2007
Last modified:	May 1, 2013
This is version 84 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.