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Protein
Submitted name:

Hamartin

Gene

TSC1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
HamartinImported
Submitted name:
Tuberous sclerosis 1Imported
Gene namesi
Name:TSC1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 9

Organism-specific databases

HGNCiHGNC:12362. TSC1.

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000165699.
PharmGKBiPA37034.

PTM / Processingi

Proteomic databases

MaxQBiQ86WV8.

Expressioni

Gene expression databases

BgeeiENSG00000165699.
ExpressionAtlasiQ86WV8. baseline and differential.

Interactioni

Binary interactionsi

Show more details

Protein-protein interaction databases

IntActiQ86WV8. 43 interactors.

Family & Domainsi

Phylogenomic databases

eggNOGiENOG410IG36. Eukaryota.
ENOG411020J. LUCA.
GeneTreeiENSGT00390000014148.
HOVERGENiHBG054903.
KOiK07206.

Family and domain databases

Gene3Di1.25.10.10. 1 hit.
InterProiView protein in InterPro
IPR011989. ARM-like.
IPR016024. ARM-type_fold.
IPR007483. Hamartin.
PANTHERiPTHR15154. PTHR15154. 1 hit.
PfamiView protein in Pfam
PF04388. Hamartin. 1 hit.
SUPFAMiSSF48371. SSF48371. 1 hit.

Sequencei

Sequence statusi: Complete.

Q86WV8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAQQANVGEL LAMLDSPMLG VRDDVTAVFK ENLNSDRGPM LVNTLVDYYL
60 70 80 90 100
ETSSQPALHI LTTLQEPHDK HLLDRINEYV GKAATRLSIL SLLGHVIRLQ
110 120 130 140 150
PSWKHKLSQA PLLPSLLKCL KMDTDVVVLT TGVLVLITML PMIPQSGKQH
160 170 180 190 200
LLDFFDIFGR LSSWCLKKPG HVAEVYLVHL HASVYALFHR LYGMYPCNFV
210 220 230 240 250
SFLRSHYSMK ENLETFEEVV KPMMEHVRIH PELVTGSKDH ELDPRRWKRL
260 270 280 290 300
ETHDVVIECA KISLDPTEAS YEDGYSVSHQ ISARFPHRSA DVTTSPYADT
310 320 330 340 350
QNSYGCATST PYSTSRLMLL NMPGQLPQTL SSPSTRLITE PPQVWCQLVC
360
LLSPLLSGEA DPLGQI
Length:366
Mass (Da):41,155
Last modified:June 1, 2003 - v1
Checksum:i9DBE1D9A25B83618
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL445645 Genomic DNA. No translation available.
BC047772 mRNA. Translation: AAH47772.1.
BC070032 mRNA. Translation: AAH70032.1.
RefSeqiNP_000359.1. NM_000368.4.
UniGeneiHs.370854.

Genome annotation databases

EnsembliENST00000403810; ENSP00000386093; ENSG00000165699.
GeneIDi7248.
KEGGihsa:7248.
UCSCiuc004cce.2. human.

Similar proteinsi

Entry informationi

Entry nameiQ86WV8_HUMAN
AccessioniPrimary (citable) accession number: Q86WV8
Entry historyiIntegrated into UniProtKB/TrEMBL: June 1, 2003
Last sequence update: June 1, 2003
Last modified: August 30, 2017
This is version 106 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported