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Protein

Oocyte-secreted protein 2

Gene

OOSP2

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Oocyte-secreted protein 2
Alternative name(s):
Placenta-specific 1-like protein
Protein TMEM122
Gene namesi
Name:OOSP2
Synonyms:PLAC1L, TMEM122
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 11

Organism-specific databases

EuPathDBiHostDB:ENSG00000149507.6.
HGNCiHGNC:26699. OOSP2.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Secreted

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000149507.
PharmGKBiPA162399666.

Polymorphism and mutation databases

BioMutaiPLAC1L.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 17Sequence analysisAdd BLAST17
ChainiPRO_000025115018 – 158Oocyte-secreted protein 2Add BLAST141

Proteomic databases

PaxDbiQ86WS3.
PeptideAtlasiQ86WS3.
PRIDEiQ86WS3.
TopDownProteomicsiQ86WS3.

PTM databases

iPTMnetiQ86WS3.
PhosphoSitePlusiQ86WS3.

Expressioni

Gene expression databases

BgeeiENSG00000149507.
CleanExiHS_PLAC1L.
ExpressionAtlasiQ86WS3. baseline and differential.
GenevisibleiQ86WS3. HS.

Organism-specific databases

HPAiHPA050914.

Interactioni

Protein-protein interaction databases

BioGridi128614. 1 interactor.
STRINGi9606.ENSP00000278855.

Structurei

3D structure databases

ProteinModelPortaliQ86WS3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the PLAC1 family.Curated

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiENOG410JAPA. Eukaryota.
ENOG41117A8. LUCA.
GeneTreeiENSGT00530000064049.
HOGENOMiHOG000115573.
HOVERGENiHBG082150.
InParanoidiQ86WS3.
OMAiECSASRK.
OrthoDBiEOG091G0WSR.
PhylomeDBiQ86WS3.
TreeFamiTF338479.

Family and domain databases

InterProiView protein in InterPro
IPR033219. Oosp2.
IPR033222. PLAC1_fam.
PANTHERiPTHR14380. PTHR14380. 1 hit.
PTHR14380:SF7. PTHR14380:SF7. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q86WS3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MALEVLMLLA VLIWTGAENL HVKISCSLDW LMVSVIPVAE SRNLYIFADE
60 70 80 90 100
LHLGMGCPAN RIHTYVYEFI YLVRDCGIRT RVVSEETLLF QTELYFTPRN
110 120 130 140 150
IDHDPQEIHL ECSTSRKSVW LTPVSTENEI KLDPSPFIAD FQTTAEELGL

LSSSPNLL
Length:158
Mass (Da):17,971
Last modified:June 1, 2003 - v1
Checksum:iEEB43D6FB8AB81FF
GO

Sequence cautioni

The sequence AP000790 differs from that shown. Reason: Erroneous gene model prediction.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti33V → A in BAC04191 (PubMed:14702039).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK093517 mRNA. Translation: BAC04191.1.
AP000790 Genomic DNA. No translation available.
BC036256 mRNA. Translation: AAH36256.1.
BC048121 mRNA. Translation: AAH48121.1.
CCDSiCCDS7979.1.
RefSeqiNP_776162.2. NM_173801.4.
UniGeneiHs.132310.

Genome annotation databases

EnsembliENST00000278855; ENSP00000278855; ENSG00000149507.
GeneIDi219990.
KEGGihsa:219990.
UCSCiuc001nol.4. human.

Similar proteinsi

Entry informationi

Entry nameiOOSP2_HUMAN
AccessioniPrimary (citable) accession number: Q86WS3
Secondary accession number(s): E9PJA4, Q8N9U6
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 3, 2006
Last sequence update: June 1, 2003
Last modified: October 25, 2017
This is version 98 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 11
    Human chromosome 11: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families