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Q86W92

- LIPB1_HUMAN

UniProt

Q86W92 - LIPB1_HUMAN

Protein

Liprin-beta-1

Gene

PPFIBP1

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 5 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 112 (01 Oct 2014)
      Sequence version 2 (07 Mar 2006)
      Previous versions | rss
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    Functioni

    May regulate the disassembly of focal adhesions. Did not bind receptor-like tyrosine phosphatases type 2A.1 Publication

    GO - Biological processi

    1. cell adhesion Source: ProtInc

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Liprin-beta-1
    Alternative name(s):
    Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 1
    Short name:
    PTPRF-interacting protein-binding protein 1
    hSGT2
    Gene namesi
    Name:PPFIBP1
    Synonyms:KIAA1230
    OrganismiHomo sapiens (Human)
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 12

    Organism-specific databases

    HGNCiHGNC:9249. PPFIBP1.

    Subcellular locationi

    GO - Cellular componenti

    1. plasma membrane Source: ProtInc

    Pathology & Biotechi

    Organism-specific databases

    PharmGKBiPA33570.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 10111011Liprin-beta-1PRO_0000191034Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei37 – 371Phosphoserine2 Publications
    Modified residuei39 – 391Phosphothreonine1 Publication
    Modified residuei40 – 401Phosphoserine2 Publications
    Modified residuei309 – 3091N6-acetyllysine1 Publication
    Modified residuei322 – 3221N6-acetyllysine1 Publication
    Modified residuei466 – 4661Phosphoserine1 Publication
    Modified residuei579 – 5791Phosphoserine1 Publication
    Modified residuei601 – 6011Phosphoserine2 Publications
    Modified residuei636 – 6361PhosphoserineBy similarity
    Modified residuei999 – 9991Phosphoserine3 Publications
    Modified residuei1001 – 10011Phosphoserine2 Publications
    Modified residuei1003 – 10031Phosphoserine1 Publication
    Modified residuei1005 – 10051Phosphothreonine1 Publication

    Keywords - PTMi

    Acetylation, Phosphoprotein

    Proteomic databases

    MaxQBiQ86W92.
    PaxDbiQ86W92.
    PRIDEiQ86W92.

    PTM databases

    PhosphoSiteiQ86W92.

    Expressioni

    Tissue specificityi

    Widely expressed. Absent in liver.1 Publication

    Gene expression databases

    ArrayExpressiQ86W92.
    BgeeiQ86W92.
    CleanExiHS_PPFIBP1.
    GenevestigatoriQ86W92.

    Organism-specific databases

    HPAiHPA001924.

    Interactioni

    Subunit structurei

    Forms homodimers and heterodimers. Interacts with S100A4 in a calcium-dependent mode.1 Publication

    Protein-protein interaction databases

    BioGridi114068. 13 interactions.
    DIPiDIP-42195N.
    IntActiQ86W92. 5 interactions.
    MINTiMINT-1683640.
    STRINGi9606.ENSP00000228425.

    Structurei

    3D structure databases

    ProteinModelPortaliQ86W92.
    SMRiQ86W92. Positions 642-894.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini647 – 71165SAM 1PROSITE-ProRule annotationAdd
    BLAST
    Domaini719 – 78264SAM 2PROSITE-ProRule annotationAdd
    BLAST
    Domaini804 – 87673SAM 3PROSITE-ProRule annotationAdd
    BLAST

    Coiled coil

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Coiled coili156 – 405250Sequence AnalysisAdd
    BLAST

    Domaini

    The N-terminal coiled coil regions mediate homodimerization preferentially and heterodimerization type beta/beta. The C-terminal, non-coiled coil regions mediate heterodimerization type beta/alpha and interaction with S100A4.

    Sequence similaritiesi

    Belongs to the liprin family. Liprin-beta subfamily.Curated
    Contains 3 SAM (sterile alpha motif) domains.PROSITE-ProRule annotation

    Keywords - Domaini

    Coiled coil, Repeat

    Phylogenomic databases

    eggNOGiNOG308732.
    HOGENOMiHOG000082535.
    HOVERGENiHBG052331.
    InParanoidiQ86W92.
    OMAiVPEEFHT.
    PhylomeDBiQ86W92.
    TreeFamiTF314207.

    Family and domain databases

    Gene3Di1.10.150.50. 3 hits.
    InterProiIPR029515. Liprin.
    IPR001660. SAM.
    IPR013761. SAM/pointed.
    IPR011510. SAM_2.
    IPR021129. SAM_type1.
    [Graphical view]
    PANTHERiPTHR12587. PTHR12587. 1 hit.
    PfamiPF00536. SAM_1. 2 hits.
    PF07647. SAM_2. 1 hit.
    [Graphical view]
    SMARTiSM00454. SAM. 3 hits.
    [Graphical view]
    SUPFAMiSSF47769. SSF47769. 3 hits.
    PROSITEiPS50105. SAM_DOMAIN. 2 hits.
    [Graphical view]

    Sequences (5)i

    Sequence statusi: Complete.

    This entry describes 5 isoformsi produced by alternative splicing. Align

    Isoform 1 (identifier: Q86W92-1) [UniParc]FASTAAdd to Basket

    This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

    « Hide

    MMSDASDMLA AALEQMDGII AGSKALEYSN GIFDCQSPTS PFMGSLRALH     50
    LVEDLRGLLE MMETDEKEGL RCQIPDSTAE TLVEWLQSQM TNGHLPGNGD 100
    VYQERLARLE NDKESLVLQV SVLTDQVEAQ GEKIRDLEFC LEEHREKVNA 150
    TEEMLQQELL SRTSLETQKL DLMAEISNLK LKLTAVEKDR LDYEDKFRDT 200
    EGLIQEINDL RLKVSEMDSE RLQYEKKLKS TKSLMAKLSS MKIKVGQMQY 250
    EKQRMEQKWE SLKDELASLK EQLEEKESEV KRLQEKLVCK MKGEGVEIVD 300
    RDIEVQKMKK AVESLMAANE EKDRKIEDLR QCLNRYKKMQ DTVVLAQGKD 350
    GEYEELLNSS SISSLLDAQG FSDLEKSPSP TPVMGSPSCD PFNTSVPEEF 400
    HTTILQVSIP SLLPATVSME TSEKSKLTPK PETSFEENDG NIILGATVDT 450
    QLCDKLLTSS LQKSSSLGNL KKETSDGEKE TIQKTSEDRA PAESRPFGTL 500
    PPRPPGQDTS MDDNPFGTRK VRSSFGRGFF KIKSNKRTAS APNLAETEKE 550
    TAEHLDLAGA SSRPKDSQRN SPFQIPPPSP DSKKKSRGIM KLFGKLRRSQ 600
    STTFNPDDMS EPEFKRGGTR ATAGPRLGWS RDLGQSNSDL DMPFAKWTKE 650
    QVCNWLMEQG LGSYLNSGKH WIASGQTLLQ ASQQDLEKEL GIKHSLHRKK 700
    LQLALQALGS EEETNHGKLD FNWVTRWLDD IGLPQYKTQF DEGRVDGRML 750
    HYMTVDDLLS LKVVSVLHHL SIKRAIQVLR INNFEPNCLR RRPSDENTIA 800
    PSEVQKWTNH RVMEWLRSVD LAEYAPNLRG SGVHGGLMVL EPRFNVETMA 850
    QLLNIPPNKT LLRRHLATHF NLLIGAEAQH QKRDAMELPD YVLLTATAKV 900
    KPKKLAFSNF GNLRKKKQED GEEYVCPMEL GQASGSASKK GFKPGLDMRL 950
    YEEDDLDRLE QMEDSEGTVR QIGAFSEGIN NLTHMLKEDD MFKDFAARSP 1000
    SASITDEDSN V 1011

    Note: No experimental confirmation available.

    Length:1,011
    Mass (Da):114,024
    Last modified:March 7, 2006 - v2
    Checksum:i20E30DD99ACD5A92
    GO
    Isoform 2 (identifier: Q86W92-2) [UniParc]FASTAAdd to Basket

    The sequence of this isoform differs from the canonical sequence as follows:
         233-263: Missing.
         302-302: D → DENFKKKLKEKN
         349-349: K → KKGK
         544-544: L → LDRKRSASAPTL

    Note: No experimental confirmation available. Contains a phosphoserine at position 523.

    Show »
    Length:1,005
    Mass (Da):113,181
    Checksum:iE399A3BB86F46BAE
    GO
    Isoform 3 (identifier: Q86W92-3) [UniParc]FASTAAdd to Basket

    The sequence of this isoform differs from the canonical sequence as follows:
         1-153: Missing.

    Note: No experimental confirmation available.

    Show »
    Length:858
    Mass (Da):96,965
    Checksum:iD5BE6B7D1D47C76A
    GO
    Isoform 4 (identifier: Q86W92-4) [UniParc]FASTAAdd to Basket

    The sequence of this isoform differs from the canonical sequence as follows:
         233-263: Missing.

    Note: No experimental confirmation available.

    Show »
    Length:980
    Mass (Da):110,297
    Checksum:iA521EFCC0589E24B
    GO
    Isoform 5 (identifier: Q86W92-5) [UniParc]FASTAAdd to Basket

    Also known as: L2

    The sequence of this isoform differs from the canonical sequence as follows:
         158-170: ELLSRTSLETQKL → VCAEARTKMGFPC
         171-1011: Missing.

    Note: Due to intron retention.

    Show »
    Length:170
    Mass (Da):18,972
    Checksum:iC281D0F4E7896A7B
    GO

    Sequence cautioni

    The sequence AAH46159.1 differs from that shown. Reason: Erroneous initiation.
    The sequence BAA86544.2 differs from that shown. Reason: Erroneous initiation.

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti308 – 3081M → K in AAH46159. (PubMed:15489334)Curated
    Sequence conflicti453 – 4531C → R in AAC26103. (PubMed:9624153)Curated
    Sequence conflicti553 – 5531E → A in AAC26103. (PubMed:9624153)Curated

    Natural variant

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Natural varianti148 – 1481V → L.5 Publications
    Corresponds to variant rs2194816 [ dbSNP | Ensembl ].
    VAR_017758

    Alternative sequence

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Alternative sequencei1 – 153153Missing in isoform 3. 1 PublicationVSP_009394Add
    BLAST
    Alternative sequencei158 – 17013ELLSR…ETQKL → VCAEARTKMGFPC in isoform 5. 2 PublicationsVSP_009395Add
    BLAST
    Alternative sequencei171 – 1011841Missing in isoform 5. 2 PublicationsVSP_009396Add
    BLAST
    Alternative sequencei233 – 26331Missing in isoform 2 and isoform 4. 2 PublicationsVSP_009397Add
    BLAST
    Alternative sequencei302 – 3021D → DENFKKKLKEKN in isoform 2. 1 PublicationVSP_009398
    Alternative sequencei349 – 3491K → KKGK in isoform 2. 1 PublicationVSP_009399
    Alternative sequencei544 – 5441L → LDRKRSASAPTL in isoform 2. 1 PublicationVSP_009400

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF034802 mRNA. Translation: AAC26103.1.
    AB033056 mRNA. Translation: BAA86544.2. Different initiation.
    AJ276680 mRNA. Translation: CAB77544.1.
    AB049149 mRNA. Translation: BAB39690.1.
    BC046159 mRNA. Translation: AAH46159.1. Different initiation.
    BC050281 mRNA. Translation: AAH50281.1.
    CCDSiCCDS55812.1. [Q86W92-1]
    CCDS55813.1. [Q86W92-4]
    CCDS55814.1. [Q86W92-3]
    CCDS8713.1. [Q86W92-2]
    RefSeqiNP_001185844.1. NM_001198915.1. [Q86W92-3]
    NP_001185845.1. NM_001198916.1.
    NP_003613.3. NM_003622.3.
    NP_803193.2. NM_177444.2.
    UniGeneiHs.172445.

    Genome annotation databases

    EnsembliENST00000228425; ENSP00000228425; ENSG00000110841. [Q86W92-2]
    ENST00000318304; ENSP00000314724; ENSG00000110841. [Q86W92-1]
    ENST00000535047; ENSP00000444046; ENSG00000110841. [Q86W92-5]
    ENST00000537927; ENSP00000445425; ENSG00000110841. [Q86W92-3]
    ENST00000542629; ENSP00000443442; ENSG00000110841. [Q86W92-4]
    GeneIDi8496.
    KEGGihsa:8496.
    UCSCiuc001rhz.2. human. [Q86W92-5]
    uc001ria.3. human. [Q86W92-4]
    uc001rib.2. human. [Q86W92-2]
    uc001ric.2. human. [Q86W92-1]
    uc001rif.2. human. [Q86W92-3]

    Polymorphism databases

    DMDMi90185247.

    Keywords - Coding sequence diversityi

    Alternative splicing, Polymorphism

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF034802 mRNA. Translation: AAC26103.1 .
    AB033056 mRNA. Translation: BAA86544.2 . Different initiation.
    AJ276680 mRNA. Translation: CAB77544.1 .
    AB049149 mRNA. Translation: BAB39690.1 .
    BC046159 mRNA. Translation: AAH46159.1 . Different initiation.
    BC050281 mRNA. Translation: AAH50281.1 .
    CCDSi CCDS55812.1. [Q86W92-1 ]
    CCDS55813.1. [Q86W92-4 ]
    CCDS55814.1. [Q86W92-3 ]
    CCDS8713.1. [Q86W92-2 ]
    RefSeqi NP_001185844.1. NM_001198915.1. [Q86W92-3 ]
    NP_001185845.1. NM_001198916.1.
    NP_003613.3. NM_003622.3.
    NP_803193.2. NM_177444.2.
    UniGenei Hs.172445.

    3D structure databases

    ProteinModelPortali Q86W92.
    SMRi Q86W92. Positions 642-894.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 114068. 13 interactions.
    DIPi DIP-42195N.
    IntActi Q86W92. 5 interactions.
    MINTi MINT-1683640.
    STRINGi 9606.ENSP00000228425.

    PTM databases

    PhosphoSitei Q86W92.

    Polymorphism databases

    DMDMi 90185247.

    Proteomic databases

    MaxQBi Q86W92.
    PaxDbi Q86W92.
    PRIDEi Q86W92.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000228425 ; ENSP00000228425 ; ENSG00000110841 . [Q86W92-2 ]
    ENST00000318304 ; ENSP00000314724 ; ENSG00000110841 . [Q86W92-1 ]
    ENST00000535047 ; ENSP00000444046 ; ENSG00000110841 . [Q86W92-5 ]
    ENST00000537927 ; ENSP00000445425 ; ENSG00000110841 . [Q86W92-3 ]
    ENST00000542629 ; ENSP00000443442 ; ENSG00000110841 . [Q86W92-4 ]
    GeneIDi 8496.
    KEGGi hsa:8496.
    UCSCi uc001rhz.2. human. [Q86W92-5 ]
    uc001ria.3. human. [Q86W92-4 ]
    uc001rib.2. human. [Q86W92-2 ]
    uc001ric.2. human. [Q86W92-1 ]
    uc001rif.2. human. [Q86W92-3 ]

    Organism-specific databases

    CTDi 8496.
    GeneCardsi GC12P027677.
    HGNCi HGNC:9249. PPFIBP1.
    HPAi HPA001924.
    MIMi 603141. gene.
    neXtProti NX_Q86W92.
    PharmGKBi PA33570.
    HUGEi Search...
    GenAtlasi Search...

    Phylogenomic databases

    eggNOGi NOG308732.
    HOGENOMi HOG000082535.
    HOVERGENi HBG052331.
    InParanoidi Q86W92.
    OMAi VPEEFHT.
    PhylomeDBi Q86W92.
    TreeFami TF314207.

    Miscellaneous databases

    ChiTaRSi PPFIBP1. human.
    GeneWikii PPFIBP1.
    GenomeRNAii 8496.
    NextBioi 31783.
    PROi Q86W92.
    SOURCEi Search...

    Gene expression databases

    ArrayExpressi Q86W92.
    Bgeei Q86W92.
    CleanExi HS_PPFIBP1.
    Genevestigatori Q86W92.

    Family and domain databases

    Gene3Di 1.10.150.50. 3 hits.
    InterProi IPR029515. Liprin.
    IPR001660. SAM.
    IPR013761. SAM/pointed.
    IPR011510. SAM_2.
    IPR021129. SAM_type1.
    [Graphical view ]
    PANTHERi PTHR12587. PTHR12587. 1 hit.
    Pfami PF00536. SAM_1. 2 hits.
    PF07647. SAM_2. 1 hit.
    [Graphical view ]
    SMARTi SM00454. SAM. 3 hits.
    [Graphical view ]
    SUPFAMi SSF47769. SSF47769. 3 hits.
    PROSITEi PS50105. SAM_DOMAIN. 2 hits.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Liprins, a family of LAR transmembrane protein-tyrosine phosphatase-interacting proteins."
      Serra-Pages C., Medley Q.G., Tang M., Hart A., Streuli M.
      J. Biol. Chem. 273:15611-15620(1998) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2), VARIANT LEU-148, TISSUE SPECIFICITY, FUNCTION.
    2. "Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro."
      Nagase T., Ishikawa K., Kikuno R., Hirosawa M., Nomura N., Ohara O.
      DNA Res. 6:337-345(1999) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 3), VARIANT LEU-148.
      Tissue: Brain.
    3. "Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones."
      Nakajima D., Okazaki N., Yamakawa H., Kikuno R., Ohara O., Nagase T.
      DNA Res. 9:99-106(2002) [PubMed] [Europe PMC] [Abstract]
      Cited for: SEQUENCE REVISION.
    4. "L2, a different isoform of Liprin beta 1, is expressed in high level in liver tissue."
      Junjian L., Cheng J., Rouli Z., Jie Z.
      Submitted (MAR-2000) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 5), VARIANT LEU-148.
    5. "hSGT2, a liprin related human gene, restores the glycolytic gene expression of the gcr2 mutant of Saccharomyces cerevisiae."
      Sato T., Jigami Y., Uemura H.
      Submitted (SEP-2000) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 5), VARIANT LEU-148.
      Tissue: Brain.
    6. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 4), VARIANT LEU-148.
      Tissue: Brain and Skin.
    7. "Liprin beta 1, a member of the family of LAR transmembrane tyrosine phosphatase-interacting proteins, is a new target for the metastasis-associated protein S100A4 (Mts1)."
      Kriajevska M., Fischer-Larsen M., Moertz E., Vorm O., Tulchinsky E., Grigorian M., Ambartsumian N., Lukanidin E.
      J. Biol. Chem. 277:5229-5235(2002) [PubMed] [Europe PMC] [Abstract]
      Cited for: INTERACTION WITH S100A4.
    8. "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks."
      Olsen J.V., Blagoev B., Gnad F., Macek B., Kumar C., Mortensen P., Mann M.
      Cell 127:635-648(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
      Tissue: Cervix carcinoma.
    9. Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-37; THR-39; SER-40; SER-466; SER-579; SER-601; SER-999; SER-1001; SER-1003 AND THR-1005, PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-523 (ISOFORM 2), IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
      Tissue: Cervix carcinoma.
    10. "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."
      Gauci S., Helbig A.O., Slijper M., Krijgsveld J., Heck A.J., Mohammed S.
      Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
      Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    11. "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."
      Mayya V., Lundgren D.H., Hwang S.-I., Rezaul K., Wu L., Eng J.K., Rodionov V., Han D.K.
      Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
      Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-601, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
      Tissue: Leukemic T-cell.
    12. "Lysine acetylation targets protein complexes and co-regulates major cellular functions."
      Choudhary C., Kumar C., Gnad F., Nielsen M.L., Rehman M., Walther T.C., Olsen J.V., Mann M.
      Science 325:834-840(2009) [PubMed] [Europe PMC] [Abstract]
      Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-309 AND LYS-322, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    13. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
      Olsen J.V., Vermeulen M., Santamaria A., Kumar C., Miller M.L., Jensen L.J., Gnad F., Cox J., Jensen T.S., Nigg E.A., Brunak S., Mann M.
      Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
      Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-37; SER-40; SER-999 AND SER-1001, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
      Tissue: Cervix carcinoma.
    14. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    15. "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."
      Rigbolt K.T., Prokhorova T.A., Akimov V., Henningsen J., Johansen P.T., Kratchmarova I., Kassem M., Mann M., Olsen J.V., Blagoev B.
      Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
      Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-999, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].

    Entry informationi

    Entry nameiLIPB1_HUMAN
    AccessioniPrimary (citable) accession number: Q86W92
    Secondary accession number(s): O75336
    , Q86X70, Q9NY03, Q9ULJ0
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: February 16, 2004
    Last sequence update: March 7, 2006
    Last modified: October 1, 2014
    This is version 112 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Human chromosome 12
      Human chromosome 12: entries, gene names and cross-references to MIM
    2. Human entries with polymorphisms or disease mutations
      List of human entries with polymorphisms or disease mutations
    3. Human polymorphisms and disease mutations
      Index of human polymorphisms and disease mutations
    4. MIM cross-references
      Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
    5. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3