Reviewed, UniProtKB/Swiss-Prot Q86W92 (LIPB1_HUMAN)

Names and origin

Protein names

Recommended name:
Liprin-beta-1

Alternative name(s):
Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 1
Short name=PTPRF-interacting protein-binding protein 1
hSGT2

Gene names

Name:	PPFIBP1
Synonyms:	KIAA1230

Organism

Homo sapiens (Human) [Complete proteome]

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Protein attributes

Sequence length	1011 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level.

General annotation (Comments)

Function	May regulate the disassembly of focal adhesions. Did not bind receptor-like tyrosine phosphatases type 2A. Ref.1
Subunit structure	Forms homodimers and heterodimers. Interacts with S100A4 in a calcium-dependent mode. Ref.7
Tissue specificity	Widely expressed. Absent in liver. Ref.1
Domain	The N-terminal coiled coil regions mediate homodimerization preferentially and heterodimerization type beta/beta. The C-terminal, non-coiled coil regions mediate heterodimerization type beta/alpha and interaction with S100A4.
Sequence similarities	Belongs to the liprin family. Liprin-beta subfamily. Contains 3 SAM (sterile alpha motif) domains.

Ontologies

Keywords
Coding sequence diversity	Alternative splicing Polymorphism
Domain	Coiled coil Repeat
PTM	Acetylation Phosphoprotein
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	cell adhesion Ref.1 Traceable author statement. Source: ProtInc
Cellular component	plasma membrane Ref.1 Non-traceable author statement. Source: ProtInc
Molecular function	protein binding Ref.1 Inferred from physical interaction. Source: IntAct
Complete GO annotation...

Binary interactions

With	Entry	#Exp.	IntAct	Notes
YWHAG	P61981	1	EBI-1045582,EBI-359832
YWHAQ	P27348	1	EBI-1045582,EBI-359854

Alternative products

This entry describes 5 isoforms produced by alternative splicing. [Align] [Select]

Isoform 1 (identifier: Q86W92-1)

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

Note: No experimental confirmation available.

Isoform 2 (identifier: Q86W92-2)

The sequence of this isoform differs from the canonical sequence as follows:
     233-263: Missing.
     302-302: D → DENFKKKLKEKN
     349-349: K → KKGK
     544-544: L → LDRKRSASAPTL

Note: No experimental confirmation available.

Isoform 3 (identifier: Q86W92-3)

The sequence of this isoform differs from the canonical sequence as follows:
     1-153: Missing.

Note: No experimental confirmation available.

Isoform 4 (identifier: Q86W92-4)

The sequence of this isoform differs from the canonical sequence as follows:
     233-263: Missing.

Note: No experimental confirmation available.

Isoform 5 (identifier: Q86W92-5)

Also known as: L2;

The sequence of this isoform differs from the canonical sequence as follows:
     158-170: ELLSRTSLETQKL → VCAEARTKMGFPC
     171-1011: Missing.

Note: Due to intron retention.

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 1011	1011	Liprin-beta-1		PRO_0000191034
Regions
	Domain	647 – 711	65	SAM 1
	Domain	719 – 782	64	SAM 2
	Domain	804 – 876	73	SAM 3
	Coiled coil	156 – 405	250	Potential
Amino acid modifications
	Modified residue	37	1	Phosphoserine Ref.9
	Modified residue	39	1	Phosphothreonine Ref.9
	Modified residue	40	1	Phosphoserine Ref.9
	Modified residue	322	1	N6-acetyllysine Ref.12
	Modified residue	466	1	Phosphoserine Ref.9
	Modified residue	540	1	Phosphoserine Ref.9
	Modified residue	579	1	Phosphoserine Ref.9
	Modified residue	601	1	Phosphoserine Ref.9 Ref.10 Ref.11
	Modified residue	999	1	Phosphoserine Ref.9 Ref.10 Ref.8
	Modified residue	1001	1	Phosphoserine Ref.9
	Modified residue	1003	1	Phosphoserine Ref.9 Ref.10 Ref.8
	Modified residue	1005	1	Phosphothreonine Ref.9 Ref.10
	Modified residue	1009	1	Phosphoserine Ref.9
Natural variations
	Alternative sequence	1 – 153	153	Missing in isoform 3.		VSP_009394
	Alternative sequence	158 – 170	13	ELLSR…ETQKL → VCAEARTKMGFPC in isoform 5.		VSP_009395
	Alternative sequence	171 – 1011	841	Missing in isoform 5.		VSP_009396
	Alternative sequence	233 – 263	31	Missing in isoform 2 and isoform 4.		VSP_009397
	Alternative sequence	302	1	D → DENFKKKLKEKN in isoform 2.		VSP_009398
	Alternative sequence	349	1	K → KKGK in isoform 2.		VSP_009399
	Alternative sequence	544	1	L → LDRKRSASAPTL in isoform 2.		VSP_009400
	Natural variant	148	1	V → L: dbSNP rs2194816. Ref.1 Ref.2 Ref.4 Ref.5 Ref.6		VAR_017758
Experimental info
	Sequence conflict	308	1	M → K in AAH46159. Ref.6
	Sequence conflict	453	1	C → R in AAC26103. Ref.1
	Sequence conflict	553	1	E → A in AAC26103. Ref.1

Sequences

	Sequence		Length	Mass (Da)
	Isoform 1 [UniParc]. Last modified March 7, 2006. Version 2. Checksum: 20E30DD99ACD5A92	FASTA	1,011	114,024
	10 20 30 40 50 60 MMSDASDMLA AALEQMDGII AGSKALEYSN GIFDCQSPTS PFMGSLRALH LVEDLRGLLE 70 80 90 100 110 120 MMETDEKEGL RCQIPDSTAE TLVEWLQSQM TNGHLPGNGD VYQERLARLE NDKESLVLQV 130 140 150 160 170 180 SVLTDQVEAQ GEKIRDLEFC LEEHREKVNA TEEMLQQELL SRTSLETQKL DLMAEISNLK 190 200 210 220 230 240 LKLTAVEKDR LDYEDKFRDT EGLIQEINDL RLKVSEMDSE RLQYEKKLKS TKSLMAKLSS 250 260 270 280 290 300 MKIKVGQMQY EKQRMEQKWE SLKDELASLK EQLEEKESEV KRLQEKLVCK MKGEGVEIVD 310 320 330 340 350 360 RDIEVQKMKK AVESLMAANE EKDRKIEDLR QCLNRYKKMQ DTVVLAQGKD GEYEELLNSS 370 380 390 400 410 420 SISSLLDAQG FSDLEKSPSP TPVMGSPSCD PFNTSVPEEF HTTILQVSIP SLLPATVSME 430 440 450 460 470 480 TSEKSKLTPK PETSFEENDG NIILGATVDT QLCDKLLTSS LQKSSSLGNL KKETSDGEKE 490 500 510 520 530 540 TIQKTSEDRA PAESRPFGTL PPRPPGQDTS MDDNPFGTRK VRSSFGRGFF KIKSNKRTAS 550 560 570 580 590 600 APNLAETEKE TAEHLDLAGA SSRPKDSQRN SPFQIPPPSP DSKKKSRGIM KLFGKLRRSQ 610 620 630 640 650 660 STTFNPDDMS EPEFKRGGTR ATAGPRLGWS RDLGQSNSDL DMPFAKWTKE QVCNWLMEQG 670 680 690 700 710 720 LGSYLNSGKH WIASGQTLLQ ASQQDLEKEL GIKHSLHRKK LQLALQALGS EEETNHGKLD 730 740 750 760 770 780 FNWVTRWLDD IGLPQYKTQF DEGRVDGRML HYMTVDDLLS LKVVSVLHHL SIKRAIQVLR 790 800 810 820 830 840 INNFEPNCLR RRPSDENTIA PSEVQKWTNH RVMEWLRSVD LAEYAPNLRG SGVHGGLMVL 850 860 870 880 890 900 EPRFNVETMA QLLNIPPNKT LLRRHLATHF NLLIGAEAQH QKRDAMELPD YVLLTATAKV 910 920 930 940 950 960 KPKKLAFSNF GNLRKKKQED GEEYVCPMEL GQASGSASKK GFKPGLDMRL YEEDDLDRLE 970 980 990 1000 1010 QMEDSEGTVR QIGAFSEGIN NLTHMLKEDD MFKDFAARSP SASITDEDSN V
	Isoform 2. Checksum: E399A3BB86F46BAE	FASTA	1,005	113,181
	10 20 30 40 50 60 MMSDASDMLA AALEQMDGII AGSKALEYSN GIFDCQSPTS PFMGSLRALH LVEDLRGLLE 70 80 90 100 110 120 MMETDEKEGL RCQIPDSTAE TLVEWLQSQM TNGHLPGNGD VYQERLARLE NDKESLVLQV 130 140 150 160 170 180 SVLTDQVEAQ GEKIRDLEFC LEEHREKVNA TEEMLQQELL SRTSLETQKL DLMAEISNLK 190 200 210 220 230 240 LKLTAVEKDR LDYEDKFRDT EGLIQEINDL RLKVSEMDSE RLQYEKKLKS TKDELASLKE 250 260 270 280 290 300 QLEEKESEVK RLQEKLVCKM KGEGVEIVDR DENFKKKLKE KNIEVQKMKK AVESLMAANE 310 320 330 340 350 360 EKDRKIEDLR QCLNRYKKMQ DTVVLAQGKK GKDGEYEELL NSSSISSLLD AQGFSDLEKS 370 380 390 400 410 420 PSPTPVMGSP SCDPFNTSVP EEFHTTILQV SIPSLLPATV SMETSEKSKL TPKPETSFEE 430 440 450 460 470 480 NDGNIILGAT VDTQLCDKLL TSSLQKSSSL GNLKKETSDG EKETIQKTSE DRAPAESRPF 490 500 510 520 530 540 GTLPPRPPGQ DTSMDDNPFG TRKVRSSFGR GFFKIKSNKR TASAPNLDRK RSASAPTLAE 550 560 570 580 590 600 TEKETAEHLD LAGASSRPKD SQRNSPFQIP PPSPDSKKKS RGIMKLFGKL RRSQSTTFNP 610 620 630 640 650 660 DDMSEPEFKR GGTRATAGPR LGWSRDLGQS NSDLDMPFAK WTKEQVCNWL MEQGLGSYLN 670 680 690 700 710 720 SGKHWIASGQ TLLQASQQDL EKELGIKHSL HRKKLQLALQ ALGSEEETNH GKLDFNWVTR 730 740 750 760 770 780 WLDDIGLPQY KTQFDEGRVD GRMLHYMTVD DLLSLKVVSV LHHLSIKRAI QVLRINNFEP 790 800 810 820 830 840 NCLRRRPSDE NTIAPSEVQK WTNHRVMEWL RSVDLAEYAP NLRGSGVHGG LMVLEPRFNV 850 860 870 880 890 900 ETMAQLLNIP PNKTLLRRHL ATHFNLLIGA EAQHQKRDAM ELPDYVLLTA TAKVKPKKLA 910 920 930 940 950 960 FSNFGNLRKK KQEDGEEYVC PMELGQASGS ASKKGFKPGL DMRLYEEDDL DRLEQMEDSE 970 980 990 1000 GTVRQIGAFS EGINNLTHML KEDDMFKDFA ARSPSASITD EDSNV
	Isoform 3. Checksum: D5BE6B7D1D47C76A	FASTA	858	96,965
	10 20 30 40 50 60 MLQQELLSRT SLETQKLDLM AEISNLKLKL TAVEKDRLDY EDKFRDTEGL IQEINDLRLK 70 80 90 100 110 120 VSEMDSERLQ YEKKLKSTKS LMAKLSSMKI KVGQMQYEKQ RMEQKWESLK DELASLKEQL 130 140 150 160 170 180 EEKESEVKRL QEKLVCKMKG EGVEIVDRDI EVQKMKKAVE SLMAANEEKD RKIEDLRQCL 190 200 210 220 230 240 NRYKKMQDTV VLAQGKDGEY EELLNSSSIS SLLDAQGFSD LEKSPSPTPV MGSPSCDPFN 250 260 270 280 290 300 TSVPEEFHTT ILQVSIPSLL PATVSMETSE KSKLTPKPET SFEENDGNII LGATVDTQLC 310 320 330 340 350 360 DKLLTSSLQK SSSLGNLKKE TSDGEKETIQ KTSEDRAPAE SRPFGTLPPR PPGQDTSMDD 370 380 390 400 410 420 NPFGTRKVRS SFGRGFFKIK SNKRTASAPN LAETEKETAE HLDLAGASSR PKDSQRNSPF 430 440 450 460 470 480 QIPPPSPDSK KKSRGIMKLF GKLRRSQSTT FNPDDMSEPE FKRGGTRATA GPRLGWSRDL 490 500 510 520 530 540 GQSNSDLDMP FAKWTKEQVC NWLMEQGLGS YLNSGKHWIA SGQTLLQASQ QDLEKELGIK 550 560 570 580 590 600 HSLHRKKLQL ALQALGSEEE TNHGKLDFNW VTRWLDDIGL PQYKTQFDEG RVDGRMLHYM 610 620 630 640 650 660 TVDDLLSLKV VSVLHHLSIK RAIQVLRINN FEPNCLRRRP SDENTIAPSE VQKWTNHRVM 670 680 690 700 710 720 EWLRSVDLAE YAPNLRGSGV HGGLMVLEPR FNVETMAQLL NIPPNKTLLR RHLATHFNLL 730 740 750 760 770 780 IGAEAQHQKR DAMELPDYVL LTATAKVKPK KLAFSNFGNL RKKKQEDGEE YVCPMELGQA 790 800 810 820 830 840 SGSASKKGFK PGLDMRLYEE DDLDRLEQME DSEGTVRQIG AFSEGINNLT HMLKEDDMFK 850 DFAARSPSAS ITDEDSNV
	Isoform 4. Checksum: A521EFCC0589E24B	FASTA	980	110,297
	10 20 30 40 50 60 MMSDASDMLA AALEQMDGII AGSKALEYSN GIFDCQSPTS PFMGSLRALH LVEDLRGLLE 70 80 90 100 110 120 MMETDEKEGL RCQIPDSTAE TLVEWLQSQM TNGHLPGNGD VYQERLARLE NDKESLVLQV 130 140 150 160 170 180 SVLTDQVEAQ GEKIRDLEFC LEEHREKVNA TEEMLQQELL SRTSLETQKL DLMAEISNLK 190 200 210 220 230 240 LKLTAVEKDR LDYEDKFRDT EGLIQEINDL RLKVSEMDSE RLQYEKKLKS TKDELASLKE 250 260 270 280 290 300 QLEEKESEVK RLQEKLVCKM KGEGVEIVDR DIEVQKMKKA VESLMAANEE KDRKIEDLRQ 310 320 330 340 350 360 CLNRYKKMQD TVVLAQGKDG EYEELLNSSS ISSLLDAQGF SDLEKSPSPT PVMGSPSCDP 370 380 390 400 410 420 FNTSVPEEFH TTILQVSIPS LLPATVSMET SEKSKLTPKP ETSFEENDGN IILGATVDTQ 430 440 450 460 470 480 LCDKLLTSSL QKSSSLGNLK KETSDGEKET IQKTSEDRAP AESRPFGTLP PRPPGQDTSM 490 500 510 520 530 540 DDNPFGTRKV RSSFGRGFFK IKSNKRTASA PNLAETEKET AEHLDLAGAS SRPKDSQRNS 550 560 570 580 590 600 PFQIPPPSPD SKKKSRGIMK LFGKLRRSQS TTFNPDDMSE PEFKRGGTRA TAGPRLGWSR 610 620 630 640 650 660 DLGQSNSDLD MPFAKWTKEQ VCNWLMEQGL GSYLNSGKHW IASGQTLLQA SQQDLEKELG 670 680 690 700 710 720 IKHSLHRKKL QLALQALGSE EETNHGKLDF NWVTRWLDDI GLPQYKTQFD EGRVDGRMLH 730 740 750 760 770 780 YMTVDDLLSL KVVSVLHHLS IKRAIQVLRI NNFEPNCLRR RPSDENTIAP SEVQKWTNHR 790 800 810 820 830 840 VMEWLRSVDL AEYAPNLRGS GVHGGLMVLE PRFNVETMAQ LLNIPPNKTL LRRHLATHFN 850 860 870 880 890 900 LLIGAEAQHQ KRDAMELPDY VLLTATAKVK PKKLAFSNFG NLRKKKQEDG EEYVCPMELG 910 920 930 940 950 960 QASGSASKKG FKPGLDMRLY EEDDLDRLEQ MEDSEGTVRQ IGAFSEGINN LTHMLKEDDM 970 980 FKDFAARSPS ASITDEDSNV
	Isoform 5 (L2). Checksum: C281D0F4E7896A7B	FASTA	170	18,972
	10 20 30 40 50 60 MMSDASDMLA AALEQMDGII AGSKALEYSN GIFDCQSPTS PFMGSLRALH LVEDLRGLLE 70 80 90 100 110 120 MMETDEKEGL RCQIPDSTAE TLVEWLQSQM TNGHLPGNGD VYQERLARLE NDKESLVLQV 130 140 150 160 170 SVLTDQVEAQ GEKIRDLEFC LEEHREKVNA TEEMLQQVCA EARTKMGFPC

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Liprins, a family of LAR transmembrane protein-tyrosine phosphatase-interacting proteins." Serra-Pages C., Medley Q.G., Tang M., Hart A., Streuli M. J. Biol. Chem. 273:15611-15620(1998) [PubMed: 9624153] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2), VARIANT LEU-148, TISSUE SPECIFICITY, FUNCTION.
[2]	"Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro." Nagase T., Ishikawa K., Kikuno R., Hirosawa M., Nomura N., Ohara O. DNA Res. 6:337-345(1999) [PubMed: 10574462] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 3), VARIANT LEU-148. Tissue: Brain.
[3]	"Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones." Nakajima D., Okazaki N., Yamakawa H., Kikuno R., Ohara O., Nagase T. DNA Res. 9:99-106(2002) [PubMed: 12168954] [Abstract] Cited for: SEQUENCE REVISION.
[4]	"L2, a different isoform of Liprin beta 1, is expressed in high level in liver tissue." Junjian L., Cheng J., Rouli Z., Jie Z. Submitted (MAR-2000) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 5), VARIANT LEU-148.
[5]	"hSGT2, a liprin related human gene, restores the glycolytic gene expression of the gcr2 mutant of Saccharomyces cerevisiae." Sato T., Jigami Y., Uemura H. Submitted (SEP-2000) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 5), VARIANT LEU-148. Tissue: Brain.
[6]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed: 15489334] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 4), VARIANT LEU-148. Tissue: Brain and Skin.
[7]	"Liprin beta 1, a member of the family of LAR transmembrane tyrosine phosphatase-interacting proteins, is a new target for the metastasis-associated protein S100A4 (Mts1)." Kriajevska M., Fischer-Larsen M., Moertz E., Vorm O., Tulchinsky E., Grigorian M., Ambartsumian N., Lukanidin E. J. Biol. Chem. 277:5229-5235(2002) [PubMed: 11836260] [Abstract] Cited for: INTERACTION WITH S100A4.
[8]	"Global, in vivo, and site-specific phosphorylation dynamics in signaling networks." Olsen J.V., Blagoev B., Gnad F., Macek B., Kumar C., Mortensen P., Mann M. Cell 127:635-648(2006) [PubMed: 17081983] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-999 AND SER-1003, MASS SPECTROMETRY. Tissue: Epithelium.
[9]	"A quantitative atlas of mitotic phosphorylation." Dephoure N., Zhou C., Villen J., Beausoleil S.A., Bakalarski C.E., Elledge S.J., Gygi S.P. Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed: 18669648] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-37; THR-39; SER-40; SER-466; SER-540; SER-579; SER-601; SER-999; SER-1001; SER-1003; THR-1005 AND SER-1009, MASS SPECTROMETRY.
[10]	"Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach." Gauci S., Helbig A.O., Slijper M., Krijgsveld J., Heck A.J., Mohammed S. Anal. Chem. 81:4493-4501(2009) [PubMed: 19413330] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-601; SER-999; SER-1003 AND THR-1005, MASS SPECTROMETRY.
[11]	"Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions." Mayya V., Lundgren D.H., Hwang S.-I., Rezaul K., Wu L., Eng J.K., Rodionov V., Han D.K. Sci. Signal. 2:RA46-RA46(2009) [PubMed: 19690332] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-601, MASS SPECTROMETRY. Tissue: T-cell.
[12]	"Lysine acetylation targets protein complexes and co-regulates major cellular functions." Choudhary C., Kumar C., Gnad F., Nielsen M.L., Rehman M., Walther T., Olsen J.V., Mann M. Science 325:834-840(2009) [PubMed: 19608861] [Abstract] Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-322, MASS SPECTROMETRY.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AF034802 mRNA. Translation: AAC26103.1. AB033056 mRNA. Translation: BAA86544.2. Different initiation. AJ276680 mRNA. Translation: CAB77544.1. AB049149 mRNA. Translation: BAB39690.1. BC046159 mRNA. Translation: AAH46159.1. Different initiation. BC050281 mRNA. Translation: AAH50281.1.
IPI	IPI00179172. IPI00302158. IPI00397366. IPI00397367. IPI00397368.
RefSeq	NP_003613.2. NP_803193.1.
UniGene	Hs.172445
3D structure databases
SMR	Q86W92. Positions 634-713, 719-786.
ModBase	Search...
Protein-protein interaction databases
IntAct	Q86W92. 3 interactions.
STRING	Q86W92.
PTM databases
PhosphoSite	Q86W92.
Proteomic databases
PRIDE	Q86W92.
Genome annotation databases
Ensembl	ENST00000318304; ENSP00000314724; ENSG00000110841; Homo sapiens. [Genome view]
GeneID	8496.
KEGG	hsa:8496.
NMPDR	fig|9606.3.peg.7335.
UCSC	uc001rhz.1. human. uc001ria.2. human. uc001rib.1. human. uc001ric.1. human. uc001rid.1. human.
Organism-specific databases
CTD	8496.
GeneCards	GC12P027568.
HGNC	HGNC:9249. PPFIBP1.
HPA	HPA001924.
MIM	603141. gene.
PharmGKB	PA33570.
HUGE	Search...
GenAtlas	Search...
Phylogenomic databases
eggNOG	prNOG08134.
HOGENOM	HBG715683.
HOVERGEN	HBG052331.
InParanoid	Q86W92.
OMA	KPETSFE.
OrthoDB	EOG99GP1S.
PhylomeDB	Q86W92.
Gene expression databases
ArrayExpress	Q86W92.
Bgee	Q86W92.
CleanEx	HS_PPFIBP1.
Genevestigator	Q86W92.
GermOnline	ENSG00000110841. Homo sapiens.
Family and domain databases
InterPro	IPR001660. SAM. IPR011510. SAM_2. IPR010993. SAM_homology. IPR013761. SAM_type. IPR021129. SAM_type1. [Graphical view]
Gene3D	G3DSA:1.10.150.50. SAM_type. 1 hit.
Pfam	PF00536. SAM_1. 2 hits. PF07647. SAM_2. 1 hit. [Graphical view]
SMART	SM00454. SAM. 3 hits. [Graphical view]
SUPFAM	SSF47769. SAM_homology. 3 hits.
PROSITE	PS50105. SAM_DOMAIN. 2 hits. [Graphical view]
ProtoNet	Search...
Other Resources
NextBio	31783.
SOURCE	Search...

Entry information

Entry name

LIPB1_HUMAN

Accession

Primary (citable) accession number: Q86W92
Secondary accession number(s): O75336 , Q86X70, Q9NY03, Q9ULJ0

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 16, 2004
Last sequence update:	March 7, 2006
Last modified:	March 2, 2010
This is version 75 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HPI (Human Proteome Initiative)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.