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Protein

Protein FAM228A

Gene

FAM228A

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Protein FAM228A
Gene namesi
Name:FAM228A
Synonyms:C2orf84
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 2

Organism-specific databases

HGNCiHGNC:34418. FAM228A.

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA164717160.

Polymorphism and mutation databases

BioMutaiFAM228A.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 206206Protein FAM228APRO_0000348445Add
BLAST

Proteomic databases

EPDiQ86W67.
PaxDbiQ86W67.
PeptideAtlasiQ86W67.
PRIDEiQ86W67.

PTM databases

iPTMnetiQ86W67.
PhosphoSiteiQ86W67.

Expressioni

Gene expression databases

BgeeiENSG00000186453.
ExpressionAtlasiQ86W67. baseline and differential.
GenevisibleiQ86W67. HS.

Organism-specific databases

HPAiHPA042520.

Interactioni

Protein-protein interaction databases

BioGridi575555. 1 interaction.
STRINGi9606.ENSP00000295150.

Structurei

3D structure databases

ProteinModelPortaliQ86W67.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the FAM228 family.Curated

Phylogenomic databases

eggNOGiENOG410IXI0. Eukaryota.
ENOG41116AT. LUCA.
GeneTreeiENSGT00530000064185.
HOGENOMiHOG000111340.
InParanoidiQ86W67.
PhylomeDBiQ86W67.
TreeFamiTF336288.

Sequencei

Sequence statusi: Complete.

Q86W67-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAATKTASYD EHFRPEKLRE WPEPESVSLM EVLAREDIDE AVCAILFKEN
60 70 80 90 100
SIVKVTVPPF VDPLFQRQQE VDEERRTGLQ CETGKRHSIK ELEEIEKARL
110 120 130 140 150
HASSPYFTFT SHCVIPKEWH KASARARSKT YKYSPEKLIY ADKKQKRKEK
160 170 180 190 200
KTADLSQAAF ERQFLSSKLS QKNKVGERKG LVSRGLGRGW HAGLCSTHEQ

HILVPE
Length:206
Mass (Da):23,752
Last modified:June 1, 2003 - v1
Checksum:iDC057FFD707AA688
GO

Natural variant

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Natural varianti140 – 1401Y → C.
Corresponds to variant rs2288073 [ dbSNP | Ensembl ].
VAR_046178

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC008073 Genomic DNA. Translation: AAY14667.1.
CH471053 Genomic DNA. Translation: EAX00756.1.
BC050462 mRNA. Translation: AAH50462.1.
CCDSiCCDS42659.1.
RefSeqiNP_001035800.1. NM_001040710.2.
UniGeneiHs.741736.

Genome annotation databases

EnsembliENST00000295150; ENSP00000295150; ENSG00000186453.
GeneIDi653140.
KEGGihsa:653140.
UCSCiuc002rfc.3. human.

Keywords - Coding sequence diversityi

Polymorphism

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC008073 Genomic DNA. Translation: AAY14667.1.
CH471053 Genomic DNA. Translation: EAX00756.1.
BC050462 mRNA. Translation: AAH50462.1.
CCDSiCCDS42659.1.
RefSeqiNP_001035800.1. NM_001040710.2.
UniGeneiHs.741736.

3D structure databases

ProteinModelPortaliQ86W67.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi575555. 1 interaction.
STRINGi9606.ENSP00000295150.

PTM databases

iPTMnetiQ86W67.
PhosphoSiteiQ86W67.

Polymorphism and mutation databases

BioMutaiFAM228A.

Proteomic databases

EPDiQ86W67.
PaxDbiQ86W67.
PeptideAtlasiQ86W67.
PRIDEiQ86W67.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000295150; ENSP00000295150; ENSG00000186453.
GeneIDi653140.
KEGGihsa:653140.
UCSCiuc002rfc.3. human.

Organism-specific databases

CTDi653140.
GeneCardsiFAM228A.
HGNCiHGNC:34418. FAM228A.
HPAiHPA042520.
neXtProtiNX_Q86W67.
PharmGKBiPA164717160.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410IXI0. Eukaryota.
ENOG41116AT. LUCA.
GeneTreeiENSGT00530000064185.
HOGENOMiHOG000111340.
InParanoidiQ86W67.
PhylomeDBiQ86W67.
TreeFamiTF336288.

Miscellaneous databases

GenomeRNAii653140.
PROiQ86W67.

Gene expression databases

BgeeiENSG00000186453.
ExpressionAtlasiQ86W67. baseline and differential.
GenevisibleiQ86W67. HS.

Family and domain databases

ProtoNetiSearch...

Entry informationi

Entry nameiF228A_HUMAN
AccessioniPrimary (citable) accession number: Q86W67
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 2, 2008
Last sequence update: June 1, 2003
Last modified: September 7, 2016
This is version 83 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 2
    Human chromosome 2: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. SIMILARITY comments
    Index of protein domains and families
  5. Uncharacterized protein families (UPF)
    List of uncharacterized protein family (UPF) entries

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.