##gff-version 3
Q86VI4	UniProtKB	Chain	1	317	.	.	.	ID=PRO_0000249721;Note=Lysosomal-associated transmembrane protein 4B	
Q86VI4	UniProtKB	Transmembrane	117	137	.	.	.	Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255	
Q86VI4	UniProtKB	Transmembrane	163	183	.	.	.	Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255	
Q86VI4	UniProtKB	Transmembrane	191	211	.	.	.	Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255	
Q86VI4	UniProtKB	Transmembrane	244	264	.	.	.	Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255	
Q86VI4	UniProtKB	Region	25	73	.	.	.	Note=Disordered;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
Q86VI4	UniProtKB	Region	205	221	.	.	.	Note=Required for NEDD4 interaction;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:22096579;Dbxref=PMID:22096579	
Q86VI4	UniProtKB	Compositional bias	36	65	.	.	.	Note=Basic and acidic residues;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
Q86VI4	UniProtKB	Alternative sequence	1	91	.	.	.	ID=VSP_059831;Note=In isoform 2. Missing	
Q86VI4	UniProtKB	Mutagenesis	296	296	.	.	.	Note=Abolishes binding to NEDD4%3B when associated with A-312. Increases localization to cell membrane%3B when associated with A-312. Retains association with HGS and enhances PIP5K1C interaction%3B when associated with A-312. Does not affect EGFR degradation%3B when associated with A-312. P->A;Ontology_term=ECO:0000269,ECO:0000269;evidence=ECO:0000269|PubMed:22096579,ECO:0000269|PubMed:25588945;Dbxref=PMID:22096579,PMID:25588945	
Q86VI4	UniProtKB	Mutagenesis	312	312	.	.	.	Note=Abolishes binding to NEDD4%3B when associated with A-296. Increases localization to cell membrane%3B when associated with A-296. Retains association with HGS and enhances PIP5K1C interaction%3B when associated with A-296. Does not affect EGFR degradation%3B when associated with A-296. P->A;Ontology_term=ECO:0000269,ECO:0000269;evidence=ECO:0000269|PubMed:22096579,ECO:0000269|PubMed:25588945;Dbxref=PMID:22096579,PMID:25588945	
Q86VI4	UniProtKB	Sequence conflict	32	32	.	.	.	Note=D->R;Ontology_term=ECO:0000305;evidence=ECO:0000305	
Q86VI4	UniProtKB	Sequence conflict	85	85	.	.	.	Note=R->S;Ontology_term=ECO:0000305;evidence=ECO:0000305	
Q86VI4	UniProtKB	Sequence conflict	179	179	.	.	.	Note=M->T;Ontology_term=ECO:0000305;evidence=ECO:0000305