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Protein
Submitted name:

Splicing factor proline/glutamine-rich (Polypyrimidine tract binding protein associated)

Gene

SFPQ

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionRNA-bindingPROSITE-ProRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Splicing factor proline/glutamine-rich (Polypyrimidine tract binding protein associated)Imported
Gene namesi
Name:SFPQImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA35690.

PTM / Processingi

Proteomic databases

PaxDbiQ86VG2.
PeptideAtlasiQ86VG2.
PRIDEiQ86VG2.

Expressioni

Gene expression databases

GenevisibleiQ86VG2. HS.

Interactioni

Protein-protein interaction databases

IntActiQ86VG2. 2 interactors.
MINTiMINT-5001818.

Structurei

3D structure databases

ProteinModelPortaliQ86VG2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini297 – 369RRMInterPro annotationAdd BLAST73
Domaini371 – 452RRMInterPro annotationAdd BLAST82

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili498 – 529Sequence analysisAdd BLAST32
Coiled coili532 – 595Sequence analysisAdd BLAST64

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG0115. Eukaryota.
ENOG410XQA0. LUCA.
HOVERGENiHBG009801.
KOiK13219.

Family and domain databases

CDDicd12948. NOPS_PSF. 1 hit.
cd12587. RRM1_PSF. 1 hit.
InterProiView protein in InterPro
IPR012975. NOPS.
IPR034526. PSF_NOPS.
IPR034525. PSF_RRM1.
IPR000504. RRM_dom.
PfamiView protein in Pfam
PF08075. NOPS. 1 hit.
PF00076. RRM_1. 2 hits.
SMARTiView protein in SMART
SM00360. RRM. 2 hits.
SUPFAMiSSF54928. SSF54928. 1 hit.
PROSITEiView protein in PROSITE
PS50102. RRM. 2 hits.

Sequencei

Sequence statusi: Complete.

Q86VG2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSRDRFRSRG GGGGGFHRRG GGGGRGGLHD FRSPPPGMGL NQNRGPMGPG
60 70 80 90 100
PGQSGPKPPI PPPPPHQQQQ QPPPQQPPPQ QPPPHQPPPH PQPHQQQQPP
110 120 130 140 150
PPPQDSSKPV VAQGPGPAPG VGSTPPASSS APPATPPTSG APPGSGPGPT
160 170 180 190 200
PTPPPAVTSA PPGAPPPTPP SSGVPTTPPQ AGGPPPPPAA VPGPGPGPKQ
210 220 230 240 250
GPGPGGPKGG KMPGGPKPGG GPGLSTPGGH PKPPRRGGGE PRGGRQHHPP
260 270 280 290 300
YHQQHHQGPP PGGPGGRSEE KISDSEGFKA NLSLLRRPGE KTYTQRCRLF
310 320 330 340 350
VGNLPADITE DEFKRLFAKY GEPGEVFINK GKGFGFIKLE SRALAEIAKA
360 370 380 390 400
ELDDTPMRGR QLRVRFATHA AALSVRNLSP YVSNELLEEA FSQFGPIERA
410 420 430 440 450
VVIVDDRGRS TGKGIVEFAS KPAARKAFER CSEGVFLLTT TPRPVIVEPL
460 470 480 490 500
EQLDDEDGLP EKLAQKNPMY QKERETPTRF AQHGTFEYEY SQRWKSLDEM
510 520 530 540 550
EKQQREQVEK NMKDAKDKLE SEMEDAYHEH QANLLRQDLM RRQEELRRME
560 570 580 590 600
ELHNQEMQKR KEMQLRQEEE RRRREEEMMI RQREMEDQMR RQREESYSRM
610 620 630 640 650
GYMDPRERDM RMGGGGAMNM GDPYGSGGQK FPPLGGGGGI GYEANPGVPP
660 670 680 690 700
ATMSGSMMGS DMRTERFGQG GAGPVGGQGP RGMGPGTPAG YGRGREEYEG

PNKKPRF
Length:707
Mass (Da):76,188
Last modified:June 1, 2003 - v1
Checksum:iB5C287EF61FD1811
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC051192 mRNA. Translation: AAH51192.1.
RefSeqiNP_005057.1. NM_005066.2.
UniGeneiHs.355934.
Hs.611911.

Genome annotation databases

GeneIDi6421.
KEGGihsa:6421.

Similar proteinsi

Entry informationi

Entry nameiQ86VG2_HUMAN
AccessioniPrimary (citable) accession number: Q86VG2
Entry historyiIntegrated into UniProtKB/TrEMBL: June 1, 2003
Last sequence update: June 1, 2003
Last modified: September 27, 2017
This is version 91 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.