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Protein

Protein FAM160B2

Gene

FAM160B2

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Protein FAM160B2
Alternative name(s):
Retinoic acid-induced protein 16
Gene namesi
Name:FAM160B2
Synonyms:RAI16
ORF Names:FP13191
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 8

Organism-specific databases

EuPathDBiHostDB:ENSG00000158863.21
HGNCiHGNC:16492 FAM160B2
neXtProtiNX_Q86V87

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000158863
PharmGKBiPA162386837

Polymorphism and mutation databases

BioMutaiFAM160B2
DMDMi145566932

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002846451 – 743Protein FAM160B2Add BLAST743

Proteomic databases

EPDiQ86V87
MaxQBiQ86V87
PaxDbiQ86V87
PeptideAtlasiQ86V87
PRIDEiQ86V87

PTM databases

iPTMnetiQ86V87
PhosphoSitePlusiQ86V87

Expressioni

Gene expression databases

BgeeiENSG00000158863
CleanExiHS_FAM160B2
ExpressionAtlasiQ86V87 baseline and differential
GenevisibleiQ86V87 HS

Organism-specific databases

HPAiHPA025040

Interactioni

Protein-protein interaction databases

BioGridi122273, 7 interactors
IntActiQ86V87, 1 interactor
STRINGi9606.ENSP00000289921

Structurei

3D structure databases

ProteinModelPortaliQ86V87
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the UPF0518 family.Curated

Phylogenomic databases

eggNOGiENOG410IN31 Eukaryota
ENOG410XTDG LUCA
GeneTreeiENSGT00760000119270
HOVERGENiHBG107875
InParanoidiQ86V87
OMAiLCSKIQQ
OrthoDBiEOG091G04PO
PhylomeDBiQ86V87
TreeFamiTF313941

Family and domain databases

InterProiView protein in InterPro
IPR019384 RetinoicA-induced_16-like
PfamiView protein in Pfam
PF10257 RAI16-like, 1 hit

Sequencei

Sequence statusi: Complete.

Q86V87-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLSRLGALLQ EAVGAREPSI DLLQAFVEHW KGITHYYIES TDESTPAKKT
60 70 80 90 100
DIPWRLKQML DILVYEEQQQ AAAGEAGPCL EYLLQHKILE TLCTLGKAEY
110 120 130 140 150
PPGMRQQVFQ FFSKVLAQVQ HPLLHYLSVH RPVQKLLRLG GTASGSVTEK
160 170 180 190 200
EEVQFTTVLC SKIQQDPELL AYILEGKKIV GRKKACGEPT ALPKDTTSHG
210 220 230 240 250
DKDCSHDGAP ARPQLDGESC GAQALNSHMP AETEELDGGT TESNLITSLL
260 270 280 290 300
GLCQSKKSRV ALKAQENLLL LVSMASPAAA TYLVQSSACC PAIVRHLCQL
310 320 330 340 350
YRSMPVFLDP ADIATLEGIS WRLPSAPSDE ASFPGKEALA AFLGWFDYCD
360 370 380 390 400
HLITEAHTVV ADALAKAVAE NFFVETLQPQ LLHVSEQSIL TSTALLTAML
410 420 430 440 450
RQLRSPALLR EAVAFLLGTD RQPEAPGDNP HTLYAHLIGH CDHLSDEISI
460 470 480 490 500
TTLRLFEELL QKPHEGIIHS LVLRNLEGRP YVAWGSPEPE SYEDTLDLEE
510 520 530 540 550
DPYFTDSFLD SGFQTPAKPR LAPATSYDGK TAVTEIVNSF LCLVPEEAKT
560 570 580 590 600
SAFLEETGYD TYVHDAYGLF QECSSRVASW GWPLTPTPLD PHEPERPFFE
610 620 630 640 650
GHFLRVLFDR MSRILDQPYS LNLQVTSVLS RLALFPHPHI HEYLLDPYIS
660 670 680 690 700
LAPGCRSLFS VLVRVIGDLM QRIQRVPQFP GKLLLVRKQL TGQAPGEQLD
710 720 730 740
HQTLLQGVVV LEEFCKELAA IAFVKFPPHD PRQNVSPAPE GQV
Length:743
Mass (Da):82,340
Last modified:April 17, 2007 - v2
Checksum:i3AD149894AB08CF5
GO

Sequence cautioni

The sequence AAH52237 differs from that shown. Reason: Erroneous initiation.Curated
The sequence AAI12148 differs from that shown. Reason: Frameshift at position 291.Curated
The sequence AAI12148 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.Curated
The sequence AAQ06676 differs from that shown. Reason: Frameshift at positions 258 and 727.Curated
The sequence BAB15137 differs from that shown. Reason: Erroneous initiation.Curated
The sequence BAG38002 differs from that shown. Reason: Erroneous initiation.Curated
The sequence BAG51483 differs from that shown. Reason: Erroneous initiation.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti182R → G in AAQ06676 (PubMed:15498874).Curated1
Sequence conflicti684L → F in AAH12865 (PubMed:15489334).Curated1
Sequence conflicti684L → F in AAH13350 (PubMed:15489334).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Natural variantiVAR_054008315T → A2 PublicationsCorresponds to variant dbSNP:rs35497596Ensembl.1
Natural variantiVAR_054009667G → R. Corresponds to variant dbSNP:rs7822461Ensembl.1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC091171 Genomic DNA No translation available.
BC012865 mRNA Translation: AAH12865.3
BC013350 mRNA Translation: AAH13350.2
BC052237 mRNA Translation: AAH52237.1 Different initiation.
BC112147 mRNA Translation: AAI12148.2 Sequence problems.
AF495722 mRNA Translation: AAQ06676.1 Frameshift.
AK025454 mRNA Translation: BAB15137.1 Different initiation.
AK315634 mRNA Translation: BAG38002.1 Different initiation.
AK055191 mRNA Translation: BAG51483.1 Different initiation.
CCDSiCCDS6021.2
RefSeqiNP_073586.5, NM_022749.5
UniGeneiHs.491223

Genome annotation databases

EnsembliENST00000289921; ENSP00000289921; ENSG00000158863
ENST00000450006; ENSP00000403288; ENSG00000158863
GeneIDi64760
KEGGihsa:64760
UCSCiuc011kyx.3 human

Keywords - Coding sequence diversityi

Polymorphism

Similar proteinsi

Entry informationi

Entry nameiF16B2_HUMAN
AccessioniPrimary (citable) accession number: Q86V87
Secondary accession number(s): B2RDQ5
, B3KNX1, Q2M211, Q71JB5, Q7L3J6, Q969T0, Q9H6W4
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 17, 2007
Last sequence update: April 17, 2007
Last modified: February 28, 2018
This is version 94 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 8
    Human chromosome 8: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. SIMILARITY comments
    Index of protein domains and families
  5. Uncharacterized protein families (UPF)
    List of uncharacterized protein family (UPF) entries
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