Q86V58 (Q86V58_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Fibulin 2 EMBL AAH51690.1

Gene names

Name:

FBLN2 EMBL AAH51690.1

Organism

Homo sapiens (Human) EMBL AAH51690.1

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Protein attributes

Sequence length	1184 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

Ontologies

Keywords
Domain	EGF-like domain SAAS SAAS018097 RuleBase RU000459
Ligand	Calcium SAAS SAAS001881
PTM	Disulfide bond SAAS SAAS018097
Gene Ontology (GO)
Cellular component	extracellular region Inferred from electronic annotation. Source: InterPro
Molecular function	calcium ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q86V58 [UniParc]. Last modified June 1, 2003. Version 1. Checksum: 4240CD6ADBB9EC5D	FASTA	1,184	126,509
	10 20 30 40 50 60 MVLLWEPAGA WLALGLALAL GPSVAAAAPR QDCTGVECPP LENCIEEALE PGACCATCVQ 70 80 90 100 110 120 QGCACEGYQY YDCLQGGFVR GRVPAGQSYF VDFGSTECSC PPGGGKISCQ FMLCPELPPN 130 140 150 160 170 180 CIEAVVVADS CPQCGQVGCV HAGHKYAAGH TVHLPPCRAC HCPDAGGELI CYQLPGCHGN 190 200 210 220 230 240 FSDAEEGDPE RHYEDPYSYD QEVAEVEAAT ALGGEVQAGA VQAGAGGPPA ALGGGSQPLS 250 260 270 280 290 300 TIQAPPWPAV LPRPTAAAAL GPPAPVQAKA RRVTEDSEEE EEEEEEREEM AVTEQLAAGG 310 320 330 340 350 360 HRGLDGLPTT APAGPSLPIQ EERAEAGARA EAGARPEENL ILDAQATSRS TGPEGVTHAP 370 380 390 400 410 420 SLGKAALVPT QAVPGSPRDP VKPSPHNILS TSLPDAAWIP PTREVPRKPQ VLPHSHVEED 430 440 450 460 470 480 TDPNSVHSIP RSSPEGSTKD LIETCCAAGQ QWAIDNDECL EIPESGTEDN VCRTAQRHCC 490 500 510 520 530 540 VSYLQEKSCM AGVLGAKEGE TCGAEDNDSC GISLYKQCCD CCGLGLRVRA EGQSCESNPN 550 560 570 580 590 600 LGYPCNHVML SCCEGEEPLI VPEVRRPPEP AAAPRRVSEA EMAGREALSL GTEAELPNSL 610 620 630 640 650 660 PGDDQDECLL LPGELCQHLC INTVGSYHCA CFPGFSLQDD GRTCRPEGHP PQPEAPQEPA 670 680 690 700 710 720 LKSEFSQVAS NTIPLPLPQP NTCKDNGPCK QVCSTVGGSA ICSCFPGYAI MADGVSCEDI 730 740 750 760 770 780 NECVTDLHTC SRGEHCVNTL GSFHCYKALT CEPGYALKDG ECEDVDECAM GTHTCQPGFL 790 800 810 820 830 840 CQNTKGSFYC QARQRCMDGF LQDPEGNCVD INECTSLSEP CRPGFSCINT VGSYTCQRNP 850 860 870 880 890 900 LICARGYHAS DDGAKCVDVN ECETGVHRCG EGQVCHNLPG SYRCDCKAGF QRDAFGRGCI 910 920 930 940 950 960 DVNECWASPG RLCQHTCENT LGSYRCSCAS GFLLAADGKR CEDVNECEAQ RCSQECANIY 970 980 990 1000 1010 1020 GSYQCYCRQG YQLAEDGHTC TDIDECAQGA GILCTFRCLN VPGSYQCACP EQGYTMTANG 1030 1040 1050 1060 1070 1080 RSCKDVDECA LGTHNCSEAE TCHNIQGSFR CLRLECPPNY VQVSKTKCER TTCHDFLECQ 1090 1100 1110 1120 1130 1140 NSPARITHYQ LNFQTGLLVP AHIFRIGPAP AFTGDTIALN IIKGNEEGYF GTRRLNAYTG 1150 1160 1170 1180 VVYLQRAVLE PRDFALDVEM KLWRQGSVTT FLAKMHIFFT TFAL

References

[1]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed: 15489334] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Testis EMBL AAH51690.1.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BC051690 mRNA. Translation: AAH51690.1.
IPI	IPI00927720.
RefSeq	NP_001004019.1. NM_001004019.1. NP_001158507.1. NM_001165035.1. NP_001989.2. NM_001998.2.
UniGene	Hs.198862.
3D structure databases
HSSP	HSSP built from PDB template 1APQ based on UniProtKB P00736.
ProteinModelPortal	Q86V58.
SMR	Q86V58. Positions 615-647.
ModBase	Search...
Protein-protein interaction databases
IntAct	Q86V58. 1 interaction.
STRING	Q86V58.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	2199.
KEGG	hsa:2199.
Organism-specific databases
CTD	2199.
Phylogenomic databases
GeneTree	ENSGT00600000084166.
HOVERGEN	HBG051559.
Gene expression databases
ArrayExpress	Q86V58.
Family and domain databases
InterPro	IPR000020. Anaphylatoxin/fibulin. IPR006210. EGF-like. IPR001881. EGF-like_Ca-bd. IPR013032. EGF-like_reg_CS. IPR000152. EGF-type_Asp/Asn_hydroxyl_site. IPR000742. EGF_3. IPR018097. EGF_Ca-bd_CS. [Graphical view]
Pfam	PF01821. ANATO. 2 hits. PF07645. EGF_CA. 6 hits. [Graphical view]
SMART	SM00104. ANATO. 3 hits. SM00181. EGF. 1 hit. SM00179. EGF_CA. 9 hits. [Graphical view]
PROSITE	PS01177. ANAPHYLATOXIN_1. 3 hits. PS01178. ANAPHYLATOXIN_2. 3 hits. PS00010. ASX_HYDROXYL. 5 hits. PS01186. EGF_2. 5 hits. PS50026. EGF_3. 4 hits. PS01187. EGF_CA. 9 hits. [Graphical view]
ProtoNet	Search...
Other
NextBio	8885.

Entry information

Entry name

Q86V58_HUMAN

Accession

Primary (citable) accession number: Q86V58

Entry history

Integrated into UniProtKB/TrEMBL:	June 1, 2003
Last sequence update:	June 1, 2003
Last modified:	January 25, 2012
This is version 80 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.