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Q86UZ1

- Q86UZ1_HUMAN

UniProt

Q86UZ1 - Q86UZ1_HUMAN

Protein
Submitted name:

CD44 antigen

Gene

CD44

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at protein leveli
  1. Functioni

    GO - Molecular functioni

    1. hyaluronic acid binding Source: InterPro

    GO - Biological processi

    1. cell adhesion Source: InterPro

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    CD44 antigenImported
    Submitted name:
    CD44 proteinImported
    Gene namesi
    Name:CD44Imported
    OrganismiHomo sapiens (Human)Imported
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 11

    Organism-specific databases

    HGNCiHGNC:1681. CD44.

    Subcellular locationi

    GO - Cellular componenti

    1. membrane Source: InterPro

    Structurei

    3D structure databases

    SMRiQ86UZ1. Positions 20-77.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Family and domain databases

    Gene3Di3.10.100.10. 1 hit.
    InterProiIPR016186. C-type_lectin-like.
    IPR016187. C-type_lectin_fold.
    IPR001231. CD44_antigen.
    IPR000538. Link.
    [Graphical view]
    PfamiPF00193. Xlink. 1 hit.
    [Graphical view]
    PRINTSiPR00658. CD44.
    SUPFAMiSSF56436. SSF56436. 1 hit.
    PROSITEiPS50963. LINK_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q86UZ1-1 [UniParc]FASTAAdd to Basket

    « Hide

    MDKFWWHAAW GLCLVPLSLA QIDLNITCRF AGVFHVEKNG RYSISRTEAA   50
    DLCKAFNSTL PTMAQMEKAL SIGFETCSST 80
    Length:80
    Mass (Da):8,931
    Last modified:June 1, 2003 - v1
    Checksum:iB0AC664418A5EB56
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL133330 Genomic DNA. No translation available.
    AL136989 Genomic DNA. No translation available.
    AL356215 Genomic DNA. No translation available.
    BC052287 mRNA. Translation: AAH52287.1.
    UniGeneiHs.502328.

    Genome annotation databases

    EnsembliENST00000425428; ENSP00000395953; ENSG00000026508.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL133330 Genomic DNA. No translation available.
    AL136989 Genomic DNA. No translation available.
    AL356215 Genomic DNA. No translation available.
    BC052287 mRNA. Translation: AAH52287.1 .
    UniGenei Hs.502328.

    3D structure databases

    SMRi Q86UZ1. Positions 20-77.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000425428 ; ENSP00000395953 ; ENSG00000026508 .

    Organism-specific databases

    HGNCi HGNC:1681. CD44.
    GenAtlasi Search...

    Miscellaneous databases

    ChiTaRSi CD44. human.

    Family and domain databases

    Gene3Di 3.10.100.10. 1 hit.
    InterProi IPR016186. C-type_lectin-like.
    IPR016187. C-type_lectin_fold.
    IPR001231. CD44_antigen.
    IPR000538. Link.
    [Graphical view ]
    Pfami PF00193. Xlink. 1 hit.
    [Graphical view ]
    PRINTSi PR00658. CD44.
    SUPFAMi SSF56436. SSF56436. 1 hit.
    PROSITEi PS50963. LINK_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
      , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Tissue: BrainImported.
    2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    3. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    4. "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."
      Mayya V., Lundgren D.H., Hwang S.I., Rezaul K., Wu L., Eng J.K., Rodionov V., Han D.K.
      Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
      Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    5. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    6. Ensembl
      Submitted (FEB-2012) to UniProtKB
      Cited for: IDENTIFICATION.

    Entry informationi

    Entry nameiQ86UZ1_HUMAN
    AccessioniPrimary (citable) accession number: Q86UZ1
    Entry historyi
    Integrated into UniProtKB/TrEMBL: June 1, 2003
    Last sequence update: June 1, 2003
    Last modified: October 1, 2014
    This is version 79 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3