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Protein
Submitted name:

CD44 antigen

Gene

CD44

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
CD44 antigenImported
Submitted name:
CD44 proteinImported
Gene namesi
Name:CD44Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 11

Organism-specific databases

HGNCiHGNC:1681. CD44.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2020Sequence analysisAdd
BLAST
Chaini21 – 8060Sequence analysisPRO_5007712719Add
BLAST

Proteomic databases

PeptideAtlasiQ86UZ1.

Expressioni

Gene expression databases

BgeeiENSG00000026508.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000398632.

Structurei

3D structure databases

SMRiQ86UZ1. Positions 20-77.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini32 – 8049LinkInterPro annotationAdd
BLAST

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiENOG410IZCP. Eukaryota.
ENOG4111S6T. LUCA.
GeneTreeiENSGT00530000063822.

Family and domain databases

Gene3Di3.10.100.10. 1 hit.
InterProiIPR016186. C-type_lectin-like.
IPR016187. C-type_lectin_fold.
IPR001231. CD44_antigen.
IPR000538. Link_dom.
[Graphical view]
PfamiPF00193. Xlink. 1 hit.
[Graphical view]
PRINTSiPR00658. CD44.
SMARTiSM00445. LINK. 1 hit.
[Graphical view]
SUPFAMiSSF56436. SSF56436. 1 hit.
PROSITEiPS50963. LINK_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q86UZ1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDKFWWHAAW GLCLVPLSLA QIDLNITCRF AGVFHVEKNG RYSISRTEAA
60 70 80
DLCKAFNSTL PTMAQMEKAL SIGFETCSST
Length:80
Mass (Da):8,931
Last modified:June 1, 2003 - v1
Checksum:iB0AC664418A5EB56
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL133330 Genomic DNA. No translation available.
AL136989 Genomic DNA. No translation available.
AL356215 Genomic DNA. No translation available.
BC052287 mRNA. Translation: AAH52287.1.
UniGeneiHs.502328.

Genome annotation databases

EnsembliENST00000425428; ENSP00000395953; ENSG00000026508.
UCSCiuc058ain.1. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL133330 Genomic DNA. No translation available.
AL136989 Genomic DNA. No translation available.
AL356215 Genomic DNA. No translation available.
BC052287 mRNA. Translation: AAH52287.1.
UniGeneiHs.502328.

3D structure databases

SMRiQ86UZ1. Positions 20-77.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000398632.

Proteomic databases

PeptideAtlasiQ86UZ1.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000425428; ENSP00000395953; ENSG00000026508.
UCSCiuc058ain.1. human.

Organism-specific databases

HGNCiHGNC:1681. CD44.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410IZCP. Eukaryota.
ENOG4111S6T. LUCA.
GeneTreeiENSGT00530000063822.

Miscellaneous databases

ChiTaRSiCD44. human.

Gene expression databases

BgeeiENSG00000026508.

Family and domain databases

Gene3Di3.10.100.10. 1 hit.
InterProiIPR016186. C-type_lectin-like.
IPR016187. C-type_lectin_fold.
IPR001231. CD44_antigen.
IPR000538. Link_dom.
[Graphical view]
PfamiPF00193. Xlink. 1 hit.
[Graphical view]
PRINTSiPR00658. CD44.
SMARTiSM00445. LINK. 1 hit.
[Graphical view]
SUPFAMiSSF56436. SSF56436. 1 hit.
PROSITEiPS50963. LINK_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ86UZ1_HUMAN
AccessioniPrimary (citable) accession number: Q86UZ1
Entry historyi
Integrated into UniProtKB/TrEMBL: June 1, 2003
Last sequence update: June 1, 2003
Last modified: September 7, 2016
This is version 98 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.