CD44

Functionⁱ

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation

GO - Molecular functionⁱ

hyaluronic acid binding Source: InterPro

View the complete GO annotation on QuickGO ...

GO - Biological processⁱ

cell adhesion Source: InterPro

View the complete GO annotation on QuickGO ...

Names & Taxonomyⁱ

Protein namesⁱ	Submitted name: CD44 antigenImported Submitted name: CD44 proteinImported
Gene namesⁱ	Name:CD44Imported
Organismⁱ	Homo sapiens (Human)Imported
Taxonomic identifierⁱ	9606 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo
Proteomesⁱ	UP000005640 Componentⁱ: Chromosome 11

Organism-specific databases

EuPathDBⁱ	HostDB:ENSG00000026508.16
Human Gene Nomenclature Database More...HGNCⁱ	HGNC:1681 CD44

Subcellular locationⁱ

GO - Cellular component

Pathology & Biotechⁱ

Organism-specific databases

Open Targets More...OpenTargetsⁱ	ENSG00000026508

OpenTargetsⁱ

ENSG00000026508

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Signal peptideⁱ	1 – 20	Sequence analysisAdd BLAST		20
ChainⁱPRO_5014311992	21 – 80	Sequence analysisAdd BLAST		60

Proteomic databases

MaxQB - The MaxQuant DataBase More...MaxQBⁱ	Q86UZ1
PRIDEⁱ	Q86UZ1

Expressionⁱ

Gene expression databases

Bgeeⁱ	ENSG00000026508
ExpressionAtlasⁱ	Q86UZ1 baseline and differential

Structureⁱ

3D structure databases

SMRⁱ	Q86UZ1
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Domainⁱ	32 – 80	LinkInterPro annotationAdd BLAST		49

Keywords - Domainⁱ

SignalSequence analysis

Phylogenomic databases

eggNOGⁱ	ENOG410IZCP Eukaryota ENOG4111S6T LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00530000063822

Family and domain databases

Gene3Dⁱ	3.10.100.10, 1 hit
InterProⁱ	View protein in InterPro IPR016186 C-type_lectin-like/link_sf IPR001231 CD44_antigen IPR016187 CTDL_fold IPR000538 Link_dom
PANTHERⁱ	PTHR10225:SF6 PTHR10225:SF6, 1 hit
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00193 Xlink, 1 hit
PRINTSⁱ	PR00658 CD44
SMARTⁱ	View protein in SMART SM00445 LINK, 1 hit
SUPFAMⁱ	SSF56436 SSF56436, 1 hit
PROSITEⁱ	View protein in PROSITE PS50963 LINK_2, 1 hit

Sequenceⁱ

Sequence statusⁱ: Complete.

Q86UZ1-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MDKFWWHAAW GLCLVPLSLA QIDLNITCRF AGVFHVEKNG RYSISRTEAA 
        60         70         80
DLCKAFNSTL PTMAQMEKAL SIGFETCSST

Length:80

Mass (Da):8,931

Last modified:June 1, 2003 - v1

Checksum:ⁱB0AC664418A5EB56

GO

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AL133330 Genomic DNA No translation available. AL136989 Genomic DNA No translation available. AL356215 Genomic DNA No translation available. BC052287 mRNA Translation: AAH52287.1
UniGeneⁱ	Hs.502328

Genome annotation databases

Ensemblⁱ	ENST00000425428; ENSP00000395953; ENSG00000026508
UCSC genome browser More...UCSCⁱ	uc058ain.1 human

Protein	Similar proteins		Species	Score	Length
Q86UZ1	CD44 isoform 4		PONAB		80
CD44 molecule (Indian blood group)		NOMLE		83

Protein	Similar proteins		Species	Score	Length
Q86UZ1	CD44 isoform 4		PONAB		80
CD44 molecule (Indian blood group)		NOMLE		83
CD44 molecule (Indian blood group)		MANLE		83
CD44 molecule (Indian blood group)		CALJA		81
CD44 isoform 4		PANTR		80

Protein	Similar proteins		Species	Score	Length
Q86UZ1	CD44 isoform 4		PONAB		80
CD44 molecule (Indian blood group)		NOMLE		83
CD44 molecule (Indian blood group)		MANLE		83
CD44 molecule (Indian blood group)		CALJA		81
CD44 isoform 4		PANTR		80

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AL133330 Genomic DNA No translation available. AL136989 Genomic DNA No translation available. AL356215 Genomic DNA No translation available. BC052287 mRNA Translation: AAH52287.1
UniGeneⁱ	Hs.502328

3D structure databases

SMRⁱ	Q86UZ1
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Proteomic databases

MaxQB - The MaxQuant DataBase More...MaxQBⁱ	Q86UZ1
PRIDEⁱ	Q86UZ1

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

Ensemblⁱ	ENST00000425428; ENSP00000395953; ENSG00000026508
UCSC genome browser More...UCSCⁱ	uc058ain.1 human

Organism-specific databases

EuPathDBⁱ	HostDB:ENSG00000026508.16
Human Gene Nomenclature Database More...HGNCⁱ	HGNC:1681 CD44
Open Targets More...OpenTargetsⁱ	ENSG00000026508
GenAtlas: human gene database More...GenAtlasⁱ	Search...

Phylogenomic databases

eggNOGⁱ	ENOG410IZCP Eukaryota ENOG4111S6T LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00530000063822

Miscellaneous databases

ChiTaRSⁱ	CD44 human

ChiTaRSⁱ

CD44 human

Gene expression databases

Bgeeⁱ	ENSG00000026508
ExpressionAtlasⁱ	Q86UZ1 baseline and differential

Family and domain databases

Gene3Dⁱ	3.10.100.10, 1 hit
InterProⁱ	View protein in InterPro IPR016186 C-type_lectin-like/link_sf IPR001231 CD44_antigen IPR016187 CTDL_fold IPR000538 Link_dom
PANTHERⁱ	PTHR10225:SF6 PTHR10225:SF6, 1 hit
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00193 Xlink, 1 hit
PRINTSⁱ	PR00658 CD44
SMARTⁱ	View protein in SMART SM00445 LINK, 1 hit
SUPFAMⁱ	SSF56436 SSF56436, 1 hit
PROSITEⁱ	View protein in PROSITE PS50963 LINK_2, 1 hit
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	Q86UZ1_HUMAN
Accessionⁱ	Q86UZ1Primary (citable) accession number: Q86UZ1
Entry historyⁱ	Integrated into UniProtKB/TrEMBL:	June 1, 2003
	Last sequence update:	June 1, 2003
	Last modified:	May 23, 2018
	This is version 118 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Unreviewed (UniProtKB/TrEMBL)
Disclaimer	Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - Q86UZ1 (Q86UZ1_HUMAN)

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CD44 antigen

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Caution

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Other locations

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Proteomic databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Phylogenomic databases

Family and domain databases

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

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Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

Pathology & Biotechⁱ

PTM / Processingⁱ

Expressionⁱ

Structureⁱ

Family & Domainsⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ