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Q86UU1

- PHLB1_HUMAN

UniProt

Q86UU1 - PHLB1_HUMAN

Protein

Pleckstrin homology-like domain family B member 1

Gene

PHLDB1

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 98 (01 Oct 2014)
      Sequence version 1 (01 Jun 2003)
      Previous versions | rss
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    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Pleckstrin homology-like domain family B member 1
    Alternative name(s):
    Protein LL5-alpha
    Gene namesi
    Name:PHLDB1
    Synonyms:KIAA0638, LL5A
    ORF Names:DLNB07
    OrganismiHomo sapiens (Human)
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 11

    Organism-specific databases

    HGNCiHGNC:23697. PHLDB1.

    Pathology & Biotechi

    Organism-specific databases

    PharmGKBiPA134917952.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 13771377Pleckstrin homology-like domain family B member 1PRO_0000053891Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei220 – 2201Phosphoserine1 Publication
    Modified residuei223 – 2231Phosphoserine1 Publication
    Modified residuei324 – 3241Phosphoserine1 Publication
    Modified residuei381 – 3811PhosphoserineBy similarity
    Modified residuei430 – 4301Phosphoserine1 Publication
    Modified residuei443 – 4431Phosphoserine1 Publication
    Modified residuei501 – 5011Phosphoserine3 Publications
    Modified residuei518 – 5181PhosphoserineBy similarity
    Modified residuei520 – 5201Phosphoserine2 Publications
    Modified residuei522 – 5221Phosphothreonine1 Publication
    Modified residuei551 – 5511Phosphoserine1 Publication
    Modified residuei555 – 5551Phosphoserine1 Publication
    Modified residuei583 – 5831Phosphoserine1 Publication

    Keywords - PTMi

    Phosphoprotein

    Proteomic databases

    MaxQBiQ86UU1.
    PaxDbiQ86UU1.
    PRIDEiQ86UU1.

    PTM databases

    PhosphoSiteiQ86UU1.

    Expressioni

    Gene expression databases

    ArrayExpressiQ86UU1.
    BgeeiQ86UU1.
    CleanExiHS_PHLDB1.
    GenevestigatoriQ86UU1.

    Organism-specific databases

    HPAiHPA037959.
    HPA038448.

    Interactioni

    Protein-protein interaction databases

    BioGridi116797. 2 interactions.
    IntActiQ86UU1. 1 interaction.
    STRINGi9606.ENSP00000354498.

    Structurei

    3D structure databases

    ProteinModelPortaliQ86UU1.
    SMRiQ86UU1. Positions 28-139, 1261-1365.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini64 – 12562FHAAdd
    BLAST
    Domaini1256 – 1370115PHPROSITE-ProRule annotationAdd
    BLAST

    Coiled coil

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Coiled coili683 – 809127Sequence AnalysisAdd
    BLAST
    Coiled coili1144 – 120865Sequence AnalysisAdd
    BLAST

    Domaini

    The PH domain mediates the binding to phosphoinositides.

    Sequence similaritiesi

    Contains 1 FHA domain.Curated
    Contains 1 PH domain.PROSITE-ProRule annotation

    Keywords - Domaini

    Coiled coil

    Phylogenomic databases

    eggNOGiNOG86245.
    HOGENOMiHOG000286004.
    HOVERGENiHBG080571.
    InParanoidiQ86UU1.
    OMAiRLWESME.
    OrthoDBiEOG779NX9.
    PhylomeDBiQ86UU1.
    TreeFamiTF329165.

    Family and domain databases

    Gene3Di2.30.29.30. 1 hit.
    2.60.200.20. 1 hit.
    InterProiIPR000253. FHA_dom.
    IPR001849. PH_domain.
    IPR011993. PH_like_dom.
    IPR008984. SMAD_FHA_domain.
    [Graphical view]
    PfamiPF00169. PH. 1 hit.
    [Graphical view]
    SMARTiSM00233. PH. 1 hit.
    [Graphical view]
    SUPFAMiSSF49879. SSF49879. 1 hit.
    PROSITEiPS50003. PH_DOMAIN. 1 hit.
    [Graphical view]

    Sequences (3)i

    Sequence statusi: Complete.

    This entry describes 3 isoformsi produced by alternative splicing. Align

    Isoform 1 (identifier: Q86UU1-1) [UniParc]FASTAAdd to Basket

    This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

    « Hide

    MDALNRNQIG PGCQTQTMVQ KGPLDLIETG KGLKVQTDKP HLVSLGSGRL     50
    STAITLLPLE EGRTVIGSAA RDISLQGPGL APEHCYIENL RGTLTLYPCG 100
    NACTIDGLPV RQPTRLTQGC MLCLGQSTFL RFNHPAEAKW MKSMIPAGGR 150
    APGPPYSPVP AESESLVNGN HTPQTATRGP SACASHSSLV SSIEKDLQEI 200
    MDSLVLEEPG AAGKKPAATS PLSPMANGGR YLLSPPTSPG AMSVGSSYEN 250
    TSPAFSPLSS PASSGSCASH SPSGQEPGPS VPPLVPARSS SYHLALQPPQ 300
    SRPSGARSES PRLSRKGGHE RPPSPGLRGL LTDSPAATVL AEARRATESP 350
    RLGGQLPVVA ISLSEYPASG ALSQPTSIPG SPKFQPPVPA PRNKIGTLQD 400
    RPPSPFREPP GSERVLTTSP SRQLVGRTFS DGLATRTLQP PESPRLGRRG 450
    LDSMRELPPL SPSLSRRALS PLPTRTTPDP KLNREVAESP RPRRWAAHGA 500
    SPEDFSLTLG ARGRRTRSPS PTLGESLAPH KGSFSGRLSP AYSLGSLTGA 550
    SPCQSPCVQR KLSSGDLRVP VTRERKNSIT EISDNEDDLL EYHRRQRQER 600
    LREQEMERLE RQRLETILNL CAEYSRADGG PEAGELPSIG EATAALALAG 650
    RRPSRGLAGA SGRSSEEPGV ATQRLWESME RSDEENLKEE CSSTESTQQE 700
    HEDAPSTKLQ GEVLALEEER AQVLGHVEQL KVRVKELEQQ LQESAREAEM 750
    ERALLQGERE AERALLQKEQ KAVDQLQEKL VALETGIQKE RDKEAEALET 800
    ETKLFEDLEF QQLERESRVE EERELAGQGL LRSKAELLRS IAKRKERLAI 850
    LDSQAGQIRA QAVQESERLA RDKNASLQLL QKEKEKLTVL ERRYHSLTGG 900
    RPFPKTTSTL KEMEKLLLPA VDLEQWYQEL MAGLGTGPAA ASPHSSPPPL 950
    PAKASRQLQV YRSKMDGEAT SPLPRTRSGP LPSSSGSSSS SSQLSVATLG 1000
    RSPSPKSALL TQNGTGSLPR NLAATLQDIE TKRQLALQQK GQQVIEEQRR 1050
    RLAELKQKAA AEAQCQWDAL HGAAPFPAGP SGFPPLMHHS ILHHLPAGRE 1100
    RGEEGEHAYD TLSLESSDSM ETSISTGGNS ACSPDNMSSA SGLDMGKIEE 1150
    MEKMLKEAHA EKNRLMESRE REMELRRQAL EEERRRREQV ERRLQSESAR 1200
    RQQLVEKEVK MREKQFSQAR PLTRYLPIRK EDFDLKTHIE SSGHGVDTCL 1250
    HVVLSSKVCR GYLVKMGGKI KSWKKRWFVF DRLKRTLSYY VDKHETKLKG 1300
    VIYFQAIEEV YYDHLRSAAK KRFFRFTMVT ESPNPALTFC VKTHDRLYYM 1350
    VAPSAEAMRI WMDVIVTGAE GYTQFMN 1377

    Note: Minor.

    Length:1,377
    Mass (Da):151,162
    Last modified:June 1, 2003 - v1
    Checksum:iDA2829CC9C2ECD3D
    GO
    Isoform 2 (identifier: Q86UU1-2) [UniParc]FASTAAdd to Basket

    The sequence of this isoform differs from the canonical sequence as follows:
         913-959: Missing.
         1321-1331: Missing.

    Note: Major.

    Show »
    Length:1,319
    Mass (Da):144,739
    Checksum:iFC6698DAB7F99188
    GO
    Isoform 3 (identifier: Q86UU1-3) [UniParc]FASTAAdd to Basket

    The sequence of this isoform differs from the canonical sequence as follows:
         913-959: Missing.
         1042-1042: Q → E
         1043-1377: Missing.

    Note: No experimental confirmation available.

    Show »
    Length:995
    Mass (Da):107,381
    Checksum:iD11D43C8C73BB999
    GO

    Sequence cautioni

    The sequence BAA31613.2 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.
    The sequence BAB84896.2 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.

    Alternative sequence

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Alternative sequencei913 – 95947Missing in isoform 2 and isoform 3. 2 PublicationsVSP_016737Add
    BLAST
    Alternative sequencei1042 – 10421Q → E in isoform 3. 1 PublicationVSP_016738
    Alternative sequencei1043 – 1377335Missing in isoform 3. 1 PublicationVSP_016739Add
    BLAST
    Alternative sequencei1321 – 133111Missing in isoform 2. 1 PublicationVSP_016740Add
    BLAST

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AB094090 mRNA. Translation: BAC76044.1.
    AB014538 mRNA. Translation: BAA31613.2. Different initiation.
    AK074070 mRNA. Translation: BAB84896.2. Different initiation.
    EF445008 Genomic DNA. Translation: ACA06043.1.
    EF445008 Genomic DNA. Translation: ACA06041.1.
    AP000941 Genomic DNA. No translation available.
    AP002954 Genomic DNA. No translation available.
    CH471065 Genomic DNA. Translation: EAW67401.1.
    BC098586 mRNA. Translation: AAH98586.1.
    CCDSiCCDS44750.1. [Q86UU1-2]
    CCDS8401.1. [Q86UU1-1]
    RefSeqiNP_001138230.1. NM_001144758.2. [Q86UU1-1]
    NP_001138231.1. NM_001144759.2. [Q86UU1-2]
    NP_055972.1. NM_015157.3. [Q86UU1-1]
    UniGeneiHs.504062.

    Genome annotation databases

    EnsembliENST00000356063; ENSP00000348359; ENSG00000019144. [Q86UU1-2]
    ENST00000361417; ENSP00000354498; ENSG00000019144. [Q86UU1-1]
    ENST00000528594; ENSP00000435520; ENSG00000019144. [Q86UU1-3]
    ENST00000530994; ENSP00000431508; ENSG00000019144. [Q86UU1-3]
    ENST00000600882; ENSP00000469820; ENSG00000019144. [Q86UU1-1]
    ENST00000601898; ENSP00000470046; ENSG00000019144. [Q86UU1-1]
    GeneIDi23187.
    KEGGihsa:23187.
    UCSCiuc001ptr.2. human. [Q86UU1-1]
    uc001ptt.3. human. [Q86UU1-2]

    Polymorphism databases

    DMDMi74723506.

    Keywords - Coding sequence diversityi

    Alternative splicing

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AB094090 mRNA. Translation: BAC76044.1 .
    AB014538 mRNA. Translation: BAA31613.2 . Different initiation.
    AK074070 mRNA. Translation: BAB84896.2 . Different initiation.
    EF445008 Genomic DNA. Translation: ACA06043.1 .
    EF445008 Genomic DNA. Translation: ACA06041.1 .
    AP000941 Genomic DNA. No translation available.
    AP002954 Genomic DNA. No translation available.
    CH471065 Genomic DNA. Translation: EAW67401.1 .
    BC098586 mRNA. Translation: AAH98586.1 .
    CCDSi CCDS44750.1. [Q86UU1-2 ]
    CCDS8401.1. [Q86UU1-1 ]
    RefSeqi NP_001138230.1. NM_001144758.2. [Q86UU1-1 ]
    NP_001138231.1. NM_001144759.2. [Q86UU1-2 ]
    NP_055972.1. NM_015157.3. [Q86UU1-1 ]
    UniGenei Hs.504062.

    3D structure databases

    ProteinModelPortali Q86UU1.
    SMRi Q86UU1. Positions 28-139, 1261-1365.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 116797. 2 interactions.
    IntActi Q86UU1. 1 interaction.
    STRINGi 9606.ENSP00000354498.

    PTM databases

    PhosphoSitei Q86UU1.

    Polymorphism databases

    DMDMi 74723506.

    Proteomic databases

    MaxQBi Q86UU1.
    PaxDbi Q86UU1.
    PRIDEi Q86UU1.

    Protocols and materials databases

    DNASUi 23187.
    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000356063 ; ENSP00000348359 ; ENSG00000019144 . [Q86UU1-2 ]
    ENST00000361417 ; ENSP00000354498 ; ENSG00000019144 . [Q86UU1-1 ]
    ENST00000528594 ; ENSP00000435520 ; ENSG00000019144 . [Q86UU1-3 ]
    ENST00000530994 ; ENSP00000431508 ; ENSG00000019144 . [Q86UU1-3 ]
    ENST00000600882 ; ENSP00000469820 ; ENSG00000019144 . [Q86UU1-1 ]
    ENST00000601898 ; ENSP00000470046 ; ENSG00000019144 . [Q86UU1-1 ]
    GeneIDi 23187.
    KEGGi hsa:23187.
    UCSCi uc001ptr.2. human. [Q86UU1-1 ]
    uc001ptt.3. human. [Q86UU1-2 ]

    Organism-specific databases

    CTDi 23187.
    GeneCardsi GC11P118478.
    HGNCi HGNC:23697. PHLDB1.
    HPAi HPA037959.
    HPA038448.
    MIMi 612834. gene.
    neXtProti NX_Q86UU1.
    PharmGKBi PA134917952.
    HUGEi Search...
    GenAtlasi Search...

    Phylogenomic databases

    eggNOGi NOG86245.
    HOGENOMi HOG000286004.
    HOVERGENi HBG080571.
    InParanoidi Q86UU1.
    OMAi RLWESME.
    OrthoDBi EOG779NX9.
    PhylomeDBi Q86UU1.
    TreeFami TF329165.

    Miscellaneous databases

    ChiTaRSi PHLDB1. human.
    GeneWikii PHLDB1.
    GenomeRNAii 23187.
    NextBioi 44659.
    PROi Q86UU1.
    SOURCEi Search...

    Gene expression databases

    ArrayExpressi Q86UU1.
    Bgeei Q86UU1.
    CleanExi HS_PHLDB1.
    Genevestigatori Q86UU1.

    Family and domain databases

    Gene3Di 2.30.29.30. 1 hit.
    2.60.200.20. 1 hit.
    InterProi IPR000253. FHA_dom.
    IPR001849. PH_domain.
    IPR011993. PH_like_dom.
    IPR008984. SMAD_FHA_domain.
    [Graphical view ]
    Pfami PF00169. PH. 1 hit.
    [Graphical view ]
    SMARTi SM00233. PH. 1 hit.
    [Graphical view ]
    SUPFAMi SSF49879. SSF49879. 1 hit.
    PROSITEi PS50003. PH_DOMAIN. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Identification of a 500-kb region of common allelic loss in chromosome 11q23 in non-MYCN amplified type of neuroblastoma."
      Kubo T., Arai Y., Ohira M., Gamou T., Maeno G., Sakiyama T., Toyoda A., Hattori M., Sakaki Y., Nakagawara A., Ohki M.
      Submitted (OCT-2002) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1).
    2. "Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro."
      Ishikawa K., Nagase T., Suyama M., Miyajima N., Tanaka A., Kotani H., Nomura N., Ohara O.
      DNA Res. 5:169-176(1998) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
      Tissue: Brain.
    3. "Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones."
      Nakajima D., Okazaki N., Yamakawa H., Kikuno R., Ohara O., Nagase T.
      DNA Res. 9:99-106(2002) [PubMed] [Europe PMC] [Abstract]
      Cited for: SEQUENCE REVISION.
    4. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
      , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
      Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
      Tissue: Spleen.
    5. NHLBI resequencing and genotyping service (RS&G)
      Submitted (FEB-2007) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    6. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    7. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    8. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 3).
      Tissue: Placenta.
    9. "Identification of pleckstrin-homology-domain-containing proteins with novel phosphoinositide-binding specificities."
      Dowler S.J., Currie R.A., Campbell D.G., Deak M., Kular G., Downes C.P., Alessi D.R.
      Biochem. J. 351:19-31(2000) [PubMed] [Europe PMC] [Abstract]
      Cited for: BINDING TO PHOSPHOINOSITIDES.
    10. "Identification and characterization of human LL5A gene and mouse Ll5a gene in silico."
      Katoh M., Katoh M.
      Int. J. Oncol. 23:1477-1483(2003) [PubMed] [Europe PMC] [Abstract]
      Cited for: ALTERNATIVE SPLICING (ISOFORMS 1 AND 2).
    11. "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks."
      Olsen J.V., Blagoev B., Gnad F., Macek B., Kumar C., Mortensen P., Mann M.
      Cell 127:635-648(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-324, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
      Tissue: Cervix carcinoma.
    12. "Combining protein-based IMAC, peptide-based IMAC, and MudPIT for efficient phosphoproteomic analysis."
      Cantin G.T., Yi W., Lu B., Park S.K., Xu T., Lee J.-D., Yates J.R. III
      J. Proteome Res. 7:1346-1351(2008) [PubMed] [Europe PMC] [Abstract]
      Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-501, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
      Tissue: Cervix carcinoma.
    13. Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-220; SER-223; SER-430; SER-443; SER-501; SER-520; SER-551; SER-555 AND SER-583, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
      Tissue: Cervix carcinoma.
    14. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
      Olsen J.V., Vermeulen M., Santamaria A., Kumar C., Miller M.L., Jensen L.J., Gnad F., Cox J., Jensen T.S., Nigg E.A., Brunak S., Mann M.
      Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
      Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-501, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
      Tissue: Cervix carcinoma.
    15. "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."
      Rigbolt K.T., Prokhorova T.A., Akimov V., Henningsen J., Johansen P.T., Kratchmarova I., Kassem M., Mann M., Olsen J.V., Blagoev B.
      Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
      Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-520 AND THR-522, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].

    Entry informationi

    Entry nameiPHLB1_HUMAN
    AccessioniPrimary (citable) accession number: Q86UU1
    Secondary accession number(s): B0YJ63
    , B0YJ64, O75133, Q4KMF8, Q8TEQ2
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: December 20, 2005
    Last sequence update: June 1, 2003
    Last modified: October 1, 2014
    This is version 98 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Human chromosome 11
      Human chromosome 11: entries, gene names and cross-references to MIM
    2. MIM cross-references
      Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
    3. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3