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Protein
Submitted name:

Calcium sensing receptor

Gene

CASR

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionReceptorImported

Names & Taxonomyi

Protein namesi
Submitted name:
Calcium sensing receptorImported
Gene namesi
Name:CASRImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei35 – 60HelicalSequence analysisAdd BLAST26
Transmembranei72 – 93HelicalSequence analysisAdd BLAST22
Transmembranei105 – 127HelicalSequence analysisAdd BLAST23
Transmembranei148 – 167HelicalSequence analysisAdd BLAST20
Transmembranei193 – 215HelicalSequence analysisAdd BLAST23
Transmembranei227 – 249HelicalSequence analysisAdd BLAST23
Transmembranei255 – 277HelicalSequence analysisAdd BLAST23

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PeptideAtlasiQ86UN7

Structurei

3D structure databases

SMRiQ86UN7
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini35 – 299G_PROTEIN_RECEP_F3_4InterPro annotationAdd BLAST265

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiKOG1056 Eukaryota
ENOG410XR6W LUCA
HOVERGENiHBG052876

Family and domain databases

Gene3Di2.10.50.301 hit
InterProiView protein in InterPro
IPR000337 GPCR_3
IPR038550 GPCR_3_9-Cys_sf
IPR017978 GPCR_3_C
IPR017979 GPCR_3_CS
PfamiView protein in Pfam
PF00003 7tm_3, 1 hit
PRINTSiPR00248 GPCRMGR
PROSITEiView protein in PROSITE
PS00981 G_PROTEIN_RECEP_F3_3, 1 hit
PS50259 G_PROTEIN_RECEP_F3_4, 1 hit

Sequencei

Sequence statusi: Fragment.

Q86UN7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
DASACNKCPD DFWSNENHTS CIAKEIEFLS WTEPFGIALT LFAVLGIFLT
60 70 80 90 100
AFVLGVFIKF RNTPIVKATN RELSYLLLFS LLCCFSSSLF FIGEPQDWTC
110 120 130 140 150
RLRQPAFGIS FVLCISCILV KTNRVLLVFE AKIPTSFHRK WWGLNLQFLL
160 170 180 190 200
VFLCTFMQIV ICVIWLYTAP PSSYRNQELE DEIIFITCHK GSLMALGFLI
210 220 230 240 250
GYTCLLAAIC FFFAFKSRKL PENFNEAKFI TFSMLIFFIV WISFIPAYAS
260 270 280 290 300
TYGKFVSAVE VIAILAASFG LLACIFFNKI YIILFKPSRN TIEEVRCSTA
310 320 330 340 350
AHAFKVAARA TLRRSNVSRK RSSSLGGSTG STPSSSISSK SNSEDPFPQP
360 370 380 390 400
ERQKQQQPLA LTQQEQQQQP LTLPQQQRSQ QQPRCKQKVI FGSGTVTFSL
410 420 430 440 450
SFDEPQKNAM AHRNSTHQNS LEAQKSSDTL TRHQPLLPLQ CGETDLDLTV
460 470 480 490 500
QETGLQGPVG GDQRPEVEDP EELSPALVVS SSQSFVISGG GSTVTENVVN

S
Length:501
Mass (Da):55,928
Last modified:June 1, 2003 - v1
Checksum:i414AF350779182C3
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY259116 Genomic DNA Translation: AAP20759.1
UniGeneiHs.435615

Similar proteinsi

Entry informationi

Entry nameiQ86UN7_HUMAN
AccessioniPrimary (citable) accession number: Q86UN7
Entry historyiIntegrated into UniProtKB/TrEMBL: June 1, 2003
Last sequence update: June 1, 2003
Last modified: March 28, 2018
This is version 73 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.