Q86UN7 (Q86UN7_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Calcium sensing receptor EMBL AAP20759.1

Gene names

Name:

CASR EMBL AAP20759.1

Organism

Homo sapiens (Human) EMBL AAP20759.1

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	501 AA.
Sequence status	Fragment.
Protein existence	Predicted

Ontologies

Keywords
Cellular component	Cell membrane SAAS SAAS017979 Membrane
Domain	Transmembrane Transmembrane helix SAAS SAAS017979
Molecular function	G-protein coupled receptor SAAS SAAS017979 Receptor Transducer
Gene Ontology (GO)
Cellular_component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW plasma membrane Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	G-protein coupled receptor activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Experimental info
	Non-terminal residue	1	1	EMBL AAP20759.1

Sequences

	Sequence		Length	Mass (Da)
	Q86UN7 [UniParc]. Last modified June 1, 2003. Version 1. Checksum: 414AF350779182C3	FASTA	501	55,928
	10 20 30 40 50 60 DASACNKCPD DFWSNENHTS CIAKEIEFLS WTEPFGIALT LFAVLGIFLT AFVLGVFIKF 70 80 90 100 110 120 RNTPIVKATN RELSYLLLFS LLCCFSSSLF FIGEPQDWTC RLRQPAFGIS FVLCISCILV 130 140 150 160 170 180 KTNRVLLVFE AKIPTSFHRK WWGLNLQFLL VFLCTFMQIV ICVIWLYTAP PSSYRNQELE 190 200 210 220 230 240 DEIIFITCHK GSLMALGFLI GYTCLLAAIC FFFAFKSRKL PENFNEAKFI TFSMLIFFIV 250 260 270 280 290 300 WISFIPAYAS TYGKFVSAVE VIAILAASFG LLACIFFNKI YIILFKPSRN TIEEVRCSTA 310 320 330 340 350 360 AHAFKVAARA TLRRSNVSRK RSSSLGGSTG STPSSSISSK SNSEDPFPQP ERQKQQQPLA 370 380 390 400 410 420 LTQQEQQQQP LTLPQQQRSQ QQPRCKQKVI FGSGTVTFSL SFDEPQKNAM AHRNSTHQNS 430 440 450 460 470 480 LEAQKSSDTL TRHQPLLPLQ CGETDLDLTV QETGLQGPVG GDQRPEVEDP EELSPALVVS 490 500 SSQSFVISGG GSTVTENVVN S

References

[1]	"A novel mutation (E767K) in the second extracellular loop of the calcium sensing receptor in a family with autosomal dominant hypocalcemia." Uckun-Kitapci A., Underwood L.E., Zhang J., Moats-Staats B. Am. J. Med. Genet. A 132:125-129(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AY259116 Genomic DNA. Translation: AAP20759.1.
IPI	IPI00012817.
UniGene	Hs.435615.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Phylogenomic databases
HOVERGEN	HBG052876.
Family and domain databases
InterPro	IPR000337. GPCR_3. IPR017978. GPCR_3_C. IPR017979. GPCR_3_CS. [Graphical view]
Pfam	PF00003. 7tm_3. 1 hit. [Graphical view]
PRINTS	PR00248. GPCRMGR.
PROSITE	PS00981. G_PROTEIN_RECEP_F3_3. 1 hit. PS50259. G_PROTEIN_RECEP_F3_4. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q86UN7_HUMAN

Accession

Primary (citable) accession number: Q86UN7

Entry history

Integrated into UniProtKB/TrEMBL:	June 1, 2003
Last sequence update:	June 1, 2003
Last modified:	April 3, 2013
This is version 56 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.