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Q86UF2

- CTGE6_HUMAN

UniProt

Q86UF2 - CTGE6_HUMAN

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Protein
cTAGE family member 6
Gene
CTAGE6, CTAGE6P
Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 2 out of 5 - Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Recommended name:
cTAGE family member 6
Short name:
Protein cTAGE-6
Gene namesi
Name:CTAGE6
Synonyms:CTAGE6P
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 7

Organism-specific databases

HGNCiHGNC:28644. CTAGE6.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei39 – 5921Helical; Reviewed prediction
Add
BLAST

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA165617921.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 777777cTAGE family member 6
PRO_0000384149Add
BLAST

Proteomic databases

MaxQBiQ86UF2.
PaxDbiQ86UF2.
PRIDEiQ86UF2.

PTM databases

PhosphoSiteiQ86UF2.

Expressioni

Gene expression databases

CleanExiHS_CTAGE6.
GenevestigatoriQ86UF2.

Organism-specific databases

HPAiHPA000387.
HPA000922.

Structurei

3D structure databases

ProteinModelPortaliQ86UF2.

Family & Domainsi

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili118 – 269152 Reviewed prediction
Add
BLAST
Coiled coili339 – 498160 Reviewed prediction
Add
BLAST

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi691 – 77585Pro-rich
Add
BLAST

Sequence similaritiesi

Belongs to the cTAGE family.

Keywords - Domaini

Coiled coil, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiNOG133684.
HOGENOMiHOG000112043.
HOVERGENiHBG051216.

Sequencei

Sequence statusi: Complete.

Q86UF2-1 [UniParc]FASTAAdd to Basket

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MEEPGATPQP YLGLVLEELR RVVAALPESM RPDENPYGFP SELVVCAAVI    50
GFFVVLLFLW RSFRSVRSRL YVGREQKLGA TLSGLIEEKC KLLEKFSLIQ 100
KEYEGYEVES SLEDASFEKA AAEEARSLEA TCEKLNRSNS ELEDEILCLE 150
KDLKEEKSKH SQQDELMADI SKSIQSLEDE SKSLKSQIAE AKIICKTFKM 200
SEERRAIAIK DALNENSQLQ TSHKQLFQQE AEVWKGEVSE LNKQKITFED 250
SKVHAEQVLN DKENHIKTLT GHLPMMKDQA AVLEEDTTDD DNLELEVNSQ 300
WENGANLDDP LKGALKKLIH AAKLNVSLKS LEGERNHIII QLSEVDKTKE 350
ELTEHIKNLQ TQQESLQSEN IYFESENQKL QQKLKIMTEF YQEDEMKLYR 400
KLTVEENYRI EEEEKLSKVE EKLSRATEQL ETYRKLAKDL EEELERTVHF 450
YQKQVISYEK RGHDNWLAAR TAERNLSDLR KENAHNKQKL TETELKFELL 500
EKDPNALDVS NTAFGREHAP NGPAPLGQRS SETRAFLSPQ TLLEDPLGLS 550
PVLPEGGGRG PRGPGNPLDH QITNERGEPS CDRLTDPHRA PSDTGSLSSP 600
VEQDCKMMFP PPGQSYPDSA LPPQREDRFY SNSERLSGSA EPRSFKMTSL 650
DKMDGSMPSE MESSRNDAKD DLGNLNVPDS SLPAENEATG PGFIPPPLAP 700
VRGPLFPVDT RGPFMRRGPP FPPPPPGTMF GASRGYFPPR DFPGPPHAPF 750
AMRNIYPPRG LPPYFHPRPG FYPNPAF 777
Length:777
Mass (Da):87,900
Last modified:September 22, 2009 - v2
Checksum:iCD26899AC51E30C0
GO

Sequence cautioni

The sequence BC043153 differs from that shown. Reason: Frameshift at position 63.

Sequence conflict

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti237 – 2371E → Q in AAI01324. 1 Publication
Sequence conflicti237 – 2371E → Q in AAI01325. 1 Publication
Sequence conflicti296 – 2961E → K in AAI01324. 1 Publication
Sequence conflicti311 – 3111L → P in AAI01324. 1 Publication
Sequence conflicti348 – 3481T → S in AAI01325. 1 Publication
Sequence conflicti364 – 3641E → A in AAI01325. 1 Publication
Sequence conflicti412 – 4121E → G in BC043153. 1 Publication

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC106862 mRNA. No translation available.
BC043153 mRNA. No translation available.
BC101323 mRNA. Translation: AAI01324.1.
BC101324 mRNA. Translation: AAI01325.1.
CCDSiCCDS64790.1.
RefSeqiNP_848656.2. NM_178561.4.
UniGeneiHs.676333.

Genome annotation databases

EnsembliENST00000470691; ENSP00000474388; ENSG00000271321.
GeneIDi340307.
KEGGihsa:340307.
UCSCiuc003wdk.4. human.

Polymorphism databases

DMDMi259016213.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC106862 mRNA. No translation available.
BC043153 mRNA. No translation available.
BC101323 mRNA. Translation: AAI01324.1 .
BC101324 mRNA. Translation: AAI01325.1 .
CCDSi CCDS64790.1.
RefSeqi NP_848656.2. NM_178561.4.
UniGenei Hs.676333.

3D structure databases

ProteinModelPortali Q86UF2.
ModBasei Search...
MobiDBi Search...

PTM databases

PhosphoSitei Q86UF2.

Polymorphism databases

DMDMi 259016213.

Proteomic databases

MaxQBi Q86UF2.
PaxDbi Q86UF2.
PRIDEi Q86UF2.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000470691 ; ENSP00000474388 ; ENSG00000271321 .
GeneIDi 340307.
KEGGi hsa:340307.
UCSCi uc003wdk.4. human.

Organism-specific databases

CTDi 340307.
GeneCardsi GC07M143459.
HGNCi HGNC:28644. CTAGE6.
HPAi HPA000387.
HPA000922.
neXtProti NX_Q86UF2.
PharmGKBi PA165617921.
GenAtlasi Search...

Phylogenomic databases

eggNOGi NOG133684.
HOGENOMi HOG000112043.
HOVERGENi HBG051216.

Miscellaneous databases

GenomeRNAii 340307.
NextBioi 97811.
PROi Q86UF2.

Gene expression databases

CleanExi HS_CTAGE6.
Genevestigatori Q86UF2.

Family and domain databases

ProtoNeti Search...

Publicationsi

  1. "The DNA sequence of human chromosome 7."
    Hillier L.W., Fulton R.S., Fulton L.A., Graves T.A., Pepin K.H., Wagner-McPherson C., Layman D., Maas J., Jaeger S., Walker R., Wylie K., Sekhon M., Becker M.C., O'Laughlin M.D., Schaller M.E., Fewell G.A., Delehaunty K.D., Miner T.L.
    , Nash W.E., Cordes M., Du H., Sun H., Edwards J., Bradshaw-Cordum H., Ali J., Andrews S., Isak A., Vanbrunt A., Nguyen C., Du F., Lamar B., Courtney L., Kalicki J., Ozersky P., Bielicki L., Scott K., Holmes A., Harkins R., Harris A., Strong C.M., Hou S., Tomlinson C., Dauphin-Kohlberg S., Kozlowicz-Reilly A., Leonard S., Rohlfing T., Rock S.M., Tin-Wollam A.-M., Abbott A., Minx P., Maupin R., Strowmatt C., Latreille P., Miller N., Johnson D., Murray J., Woessner J.P., Wendl M.C., Yang S.-P., Schultz B.R., Wallis J.W., Spieth J., Bieri T.A., Nelson J.O., Berkowicz N., Wohldmann P.E., Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Bedell J.A., Mardis E.R., Clifton S.W., Chissoe S.L., Marra M.A., Raymond C., Haugen E., Gillett W., Zhou Y., James R., Phelps K., Iadanoto S., Bubb K., Simms E., Levy R., Clendenning J., Kaul R., Kent W.J., Furey T.S., Baertsch R.A., Brent M.R., Keibler E., Flicek P., Bork P., Suyama M., Bailey J.A., Portnoy M.E., Torrents D., Chinwalla A.T., Gish W.R., Eddy S.R., McPherson J.D., Olson M.V., Eichler E.E., Green E.D., Waterston R.H., Wilson R.K.
    Nature 424:157-164(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Testis.

Entry informationi

Entry nameiCTGE6_HUMAN
AccessioniPrimary (citable) accession number: Q86UF2
Secondary accession number(s): A4FU29, Q3ZCM5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 4, 2005
Last sequence update: September 22, 2009
Last modified: July 9, 2014
This is version 73 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 7
    Human chromosome 7: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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