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Q86UF2 (CTGE6_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 71. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
cTAGE family member 6

Short name=Protein cTAGE-6
Gene names
Name:CTAGE6
Synonyms:CTAGE6P
OrganismHomo sapiens (Human) [Reference proteome]
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Protein attributes

Sequence length777 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Subcellular location

Membrane; Single-pass membrane protein Potential.

Sequence similarities

Belongs to the cTAGE family.

Sequence caution

The sequence BC043153 differs from that shown. Reason: Frameshift at position 63.

Ontologies

Keywords
   Cellular componentMembrane
   DomainCoiled coil
Transmembrane
Transmembrane helix
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Cellular_componentintegral component of membrane

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 777777cTAGE family member 6
PRO_0000384149

Regions

Transmembrane39 – 5921Helical; Potential
Coiled coil118 – 269152 Potential
Coiled coil339 – 498160 Potential
Compositional bias691 – 77585Pro-rich

Experimental info

Sequence conflict2371E → Q in AAI01324. Ref.2
Sequence conflict2371E → Q in AAI01325. Ref.2
Sequence conflict2961E → K in AAI01324. Ref.2
Sequence conflict3111L → P in AAI01324. Ref.2
Sequence conflict3481T → S in AAI01325. Ref.2
Sequence conflict3641E → A in AAI01325. Ref.2
Sequence conflict4121E → G in BC043153. Ref.2

Sequences

Sequence LengthMass (Da)Tools
Q86UF2 [UniParc].

Last modified September 22, 2009. Version 2.
Checksum: CD26899AC51E30C0

FASTA77787,900
        10         20         30         40         50         60 
MEEPGATPQP YLGLVLEELR RVVAALPESM RPDENPYGFP SELVVCAAVI GFFVVLLFLW 

        70         80         90        100        110        120 
RSFRSVRSRL YVGREQKLGA TLSGLIEEKC KLLEKFSLIQ KEYEGYEVES SLEDASFEKA 

       130        140        150        160        170        180 
AAEEARSLEA TCEKLNRSNS ELEDEILCLE KDLKEEKSKH SQQDELMADI SKSIQSLEDE 

       190        200        210        220        230        240 
SKSLKSQIAE AKIICKTFKM SEERRAIAIK DALNENSQLQ TSHKQLFQQE AEVWKGEVSE 

       250        260        270        280        290        300 
LNKQKITFED SKVHAEQVLN DKENHIKTLT GHLPMMKDQA AVLEEDTTDD DNLELEVNSQ 

       310        320        330        340        350        360 
WENGANLDDP LKGALKKLIH AAKLNVSLKS LEGERNHIII QLSEVDKTKE ELTEHIKNLQ 

       370        380        390        400        410        420 
TQQESLQSEN IYFESENQKL QQKLKIMTEF YQEDEMKLYR KLTVEENYRI EEEEKLSKVE 

       430        440        450        460        470        480 
EKLSRATEQL ETYRKLAKDL EEELERTVHF YQKQVISYEK RGHDNWLAAR TAERNLSDLR 

       490        500        510        520        530        540 
KENAHNKQKL TETELKFELL EKDPNALDVS NTAFGREHAP NGPAPLGQRS SETRAFLSPQ 

       550        560        570        580        590        600 
TLLEDPLGLS PVLPEGGGRG PRGPGNPLDH QITNERGEPS CDRLTDPHRA PSDTGSLSSP 

       610        620        630        640        650        660 
VEQDCKMMFP PPGQSYPDSA LPPQREDRFY SNSERLSGSA EPRSFKMTSL DKMDGSMPSE 

       670        680        690        700        710        720 
MESSRNDAKD DLGNLNVPDS SLPAENEATG PGFIPPPLAP VRGPLFPVDT RGPFMRRGPP 

       730        740        750        760        770 
FPPPPPGTMF GASRGYFPPR DFPGPPHAPF AMRNIYPPRG LPPYFHPRPG FYPNPAF 

« Hide

References

[1]"The DNA sequence of human chromosome 7."
Hillier L.W., Fulton R.S., Fulton L.A., Graves T.A., Pepin K.H., Wagner-McPherson C., Layman D., Maas J., Jaeger S., Walker R., Wylie K., Sekhon M., Becker M.C., O'Laughlin M.D., Schaller M.E., Fewell G.A., Delehaunty K.D., Miner T.L. expand/collapse author list , Nash W.E., Cordes M., Du H., Sun H., Edwards J., Bradshaw-Cordum H., Ali J., Andrews S., Isak A., Vanbrunt A., Nguyen C., Du F., Lamar B., Courtney L., Kalicki J., Ozersky P., Bielicki L., Scott K., Holmes A., Harkins R., Harris A., Strong C.M., Hou S., Tomlinson C., Dauphin-Kohlberg S., Kozlowicz-Reilly A., Leonard S., Rohlfing T., Rock S.M., Tin-Wollam A.-M., Abbott A., Minx P., Maupin R., Strowmatt C., Latreille P., Miller N., Johnson D., Murray J., Woessner J.P., Wendl M.C., Yang S.-P., Schultz B.R., Wallis J.W., Spieth J., Bieri T.A., Nelson J.O., Berkowicz N., Wohldmann P.E., Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Bedell J.A., Mardis E.R., Clifton S.W., Chissoe S.L., Marra M.A., Raymond C., Haugen E., Gillett W., Zhou Y., James R., Phelps K., Iadanoto S., Bubb K., Simms E., Levy R., Clendenning J., Kaul R., Kent W.J., Furey T.S., Baertsch R.A., Brent M.R., Keibler E., Flicek P., Bork P., Suyama M., Bailey J.A., Portnoy M.E., Torrents D., Chinwalla A.T., Gish W.R., Eddy S.R., McPherson J.D., Olson M.V., Eichler E.E., Green E.D., Waterston R.H., Wilson R.K.
Nature 424:157-164(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[2]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Tissue: Testis.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AC106862 mRNA. No translation available.
BC043153 mRNA. No translation available.
BC101323 mRNA. Translation: AAI01324.1.
BC101324 mRNA. Translation: AAI01325.1.
RefSeqNP_848656.2. NM_178561.4.
UniGeneHs.676333.

3D structure databases

ProteinModelPortalQ86UF2.
ModBaseSearch...
MobiDBSearch...

PTM databases

PhosphoSiteQ86UF2.

Polymorphism databases

DMDM259016213.

Proteomic databases

PaxDbQ86UF2.
PRIDEQ86UF2.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENST00000470691; ENSP00000474388; ENSG00000271321.
GeneID340307.
KEGGhsa:340307.
UCSCuc003wdk.4. human.

Organism-specific databases

CTD340307.
GeneCardsGC07M143459.
HGNCHGNC:28644. CTAGE6.
HPAHPA000387.
HPA000922.
neXtProtNX_Q86UF2.
PharmGKBPA165617921.
GenAtlasSearch...

Phylogenomic databases

eggNOGNOG133684.
HOGENOMHOG000112043.
HOVERGENHBG051216.

Gene expression databases

CleanExHS_CTAGE6.
GenevestigatorQ86UF2.

Family and domain databases

ProtoNetSearch...

Other

GenomeRNAi340307.
NextBio97811.
PROQ86UF2.

Entry information

Entry nameCTGE6_HUMAN
AccessionPrimary (citable) accession number: Q86UF2
Secondary accession number(s): A4FU29, Q3ZCM5
Entry history
Integrated into UniProtKB/Swiss-Prot: January 4, 2005
Last sequence update: September 22, 2009
Last modified: February 19, 2014
This is version 71 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Relevant documents

SIMILARITY comments

Index of protein domains and families

Human chromosome 7

Human chromosome 7: entries, gene names and cross-references to MIM