Q86UD1 (OAF_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Out at first protein homolog

Alternative name(s):
HCV NS5A-transactivated protein 13 target protein 2

Gene names

Name:	OAF
Synonyms:	NS5ATP13TP2

Organism

Homo sapiens (Human)

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Protein attributes

Sequence length	273 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at transcript level

General annotation (Comments)

Sequence similarities

Belongs to the OAF family.

Ontologies

Keywords
Coding sequence diversity	Polymorphism
Domain	Signal
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
None. [Check GOA]

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 27	27	Potential
	Chain	28 – 273	246	Out at first protein homolog		PRO_0000292427
Natural variations
	Natural variant	210	1	H → R. Corresponds to variant rs2508489 [ dbSNP | Ensembl ].		VAR_032993
	Natural variant	217	1	R → H. Corresponds to variant rs2508490 [ dbSNP | Ensembl ].		VAR_032994

Sequences

	Sequence		Length	Mass (Da)
	Q86UD1 [UniParc]. Last modified June 1, 2003. Version 1. Checksum: EC752B522917F496	FASTA	273	30,688
	10 20 30 40 50 60 MRLPGVPLAR PALLLLLPLL APLLGTGAPA ELRVRVRLPD GQVTEESLQA DSDADSISLE 70 80 90 100 110 120 LRKPDGTLVS FTADFKKDVK VFRALILGEL EKGQSQFQAL CFVTQLQHNE IIPSEAMAKL 130 140 150 160 170 180 RQKNPRAVRQ AEEVRGLEHL HMDVAVNFSQ GALLSPHLHN VCAEAVDAIY TRQEDVRFWL 190 200 210 220 230 240 EQGVDSSVFE ALPKASEQAE LPRCRQVGDH GKPCVCRYGL SLAWYPCMLK YCHSRDRPTP 250 260 270 YKCGIRSCQK SYSFDFYVPQ RQLCLWDEDP YPG

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Screening and cloning of the target genes transactivated by human gene 13 transactivated by nonstructural protein 5A of hepatitis C virus using suppression subtractive hybridization technique." Dang X., Cheng J., Deng H. Submitted (NOV-2003) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [MRNA].
[2]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed: 15489334] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Brain.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AY459296 mRNA. Translation: AAR23238.1. BC047726 mRNA. Translation: AAH47726.1.
IPI	IPI00328703.
RefSeq	NP_848602.1. NM_178507.2.
UniGene	Hs.445081.
3D structure databases
ProteinModelPortal	Q86UD1.
ModBase	Search...
Protein-protein interaction databases
STRING	Q86UD1.
Polymorphism databases
DMDM	74727479.
Proteomic databases
PRIDE	Q86UD1.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENST00000328965; ENSP00000332613; ENSG00000184232.
GeneID	220323.
KEGG	hsa:220323.
UCSC	uc001pxb.1. human.
Organism-specific databases
CTD	220323.
GeneCards	GC11P120081.
HGNC	HGNC:28752. OAF.
HPA	HPA047412.
neXtProt	NX_Q86UD1.
PharmGKB	PA142671234.
GenAtlas	Search...
Phylogenomic databases
eggNOG	prNOG07810.
GeneTree	ENSGT00390000012008.
HOGENOM	HBG444293.
HOVERGEN	HBG097590.
InParanoid	Q86UD1.
OMA	FDFYVPQ.
OrthoDB	EOG4QVCCQ.
PhylomeDB	Q86UD1.
Gene expression databases
ArrayExpress	Q86UD1.
Bgee	Q86UD1.
CleanEx	HS_OAF.
Genevestigator	Q86UD1.
Family and domain databases
ProtoNet	Search...
Other
NextBio	91040.

Entry information

Entry name

OAF_HUMAN

Accession

Primary (citable) accession number: Q86UD1

Entry history

Integrated into UniProtKB/Swiss-Prot:	June 26, 2007
Last sequence update:	June 1, 2003
Last modified:	January 25, 2012
This is version 51 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.