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Protein
Submitted name:

RARB protein

Gene

RARB

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi1 – 51Nuclear receptorPROSITE-ProRule annotationAdd BLAST51

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-bindingPROSITE-ProRule annotationSAAS annotation
Biological processTranscription, Transcription regulationPROSITE-ProRule annotationSAAS annotation
LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
RARB proteinImported
Gene namesi
Name:RARBImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

  • Nucleus PROSITE-ProRule annotationSAAS annotation

GO - Cellular componenti

Keywords - Cellular componenti

NucleusPROSITE-ProRule annotationSAAS annotation

PTM / Processingi

Proteomic databases

PaxDbiQ86UC5.
PeptideAtlasiQ86UC5.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000332296.

Structurei

3D structure databases

ProteinModelPortaliQ86UC5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 51Nuclear receptor DNA-bindingInterPro annotationAdd BLAST51

Sequence similaritiesi

Belongs to the nuclear hormone receptor family.SAAS annotation

Keywords - Domaini

Zinc-fingerPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG3575. Eukaryota.
ENOG410XRZC. LUCA.
HOVERGENiHBG005606.

Family and domain databases

Gene3Di1.10.565.10. 1 hit.
3.30.50.10. 1 hit.
InterProiView protein in InterPro
IPR000536. Nucl_hrmn_rcpt_lig-bd.
IPR001723. Nuclear_hrmn_rcpt.
IPR003078. Retinoic_acid_rcpt.
IPR001628. Znf_hrmn_rcpt.
IPR013088. Znf_NHR/GATA.
PfamiView protein in Pfam
PF00104. Hormone_recep. 1 hit.
PF00105. zf-C4. 1 hit.
PRINTSiPR01292. RETNOICACIDR.
PR00398. STRDHORMONER.
SMARTiView protein in SMART
SM00430. HOLI. 1 hit.
SM00399. ZnF_C4. 1 hit.
SUPFAMiSSF48508. SSF48508. 1 hit.
PROSITEiView protein in PROSITE
PS51030. NUCLEAR_REC_DBD_2. 1 hit.

Sequencei

Sequence statusi: Fragment.

Q86UC5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
GFFRRSIQKN MIYTCHRDKN CVINKVTRNR CQYCRLQKCF EVGMSKESVR
60 70 80 90 100
NDRNKKKKET SKQECTESYE MTAELDDLTE KIRKAHQETF PSLCQLGKYT
110 120 130 140 150
TNSSADHRVR LDLGLWDKFS ELATKCIIKI VEFAKRLPGF TGLTIADQIT
160 170 180 190 200
LLKAACLDIL ILRICTRYTP EQDTMTFSDG LTLNRTQMHN AGFGPLTDLV
210 220 230 240 250
FTFANQLLPL EMDDTETGLL SAICLICGDR QDLEEPTKVD KLQEPLLEAL
260 270 280 290 300
KIYIRKRRPS KPHMFPKILM KITDLRSISA KGTERVITLK MEIPGSMPPL
310 320 330 340
IQEMLENSEG HEPLTPSSSG NTAEHSPSIS PSSVENSGVS QSPLVQ
Length:346
Mass (Da):39,196
Last modified:March 1, 2004 - v2
Checksum:i70C1ED2DFF2E6E17
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC050415 mRNA. Translation: AAH50415.2.
RefSeqiNP_000956.2. NM_000965.4.
NP_001277205.1. NM_001290276.1.
UniGeneiHs.543218.
Hs.581530.
Hs.654490.
Hs.733004.

Genome annotation databases

GeneIDi5915.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC050415 mRNA. Translation: AAH50415.2.
RefSeqiNP_000956.2. NM_000965.4.
NP_001277205.1. NM_001290276.1.
UniGeneiHs.543218.
Hs.581530.
Hs.654490.
Hs.733004.

3D structure databases

ProteinModelPortaliQ86UC5.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000332296.

Proteomic databases

PaxDbiQ86UC5.
PeptideAtlasiQ86UC5.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi5915.

Organism-specific databases

CTDi5915.

Phylogenomic databases

eggNOGiKOG3575. Eukaryota.
ENOG410XRZC. LUCA.
HOVERGENiHBG005606.

Miscellaneous databases

GenomeRNAii5915.

Family and domain databases

Gene3Di1.10.565.10. 1 hit.
3.30.50.10. 1 hit.
InterProiView protein in InterPro
IPR000536. Nucl_hrmn_rcpt_lig-bd.
IPR001723. Nuclear_hrmn_rcpt.
IPR003078. Retinoic_acid_rcpt.
IPR001628. Znf_hrmn_rcpt.
IPR013088. Znf_NHR/GATA.
PfamiView protein in Pfam
PF00104. Hormone_recep. 1 hit.
PF00105. zf-C4. 1 hit.
PRINTSiPR01292. RETNOICACIDR.
PR00398. STRDHORMONER.
SMARTiView protein in SMART
SM00430. HOLI. 1 hit.
SM00399. ZnF_C4. 1 hit.
SUPFAMiSSF48508. SSF48508. 1 hit.
PROSITEiView protein in PROSITE
PS51030. NUCLEAR_REC_DBD_2. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiQ86UC5_HUMAN
AccessioniPrimary (citable) accession number: Q86UC5
Entry historyiIntegrated into UniProtKB/TrEMBL: June 1, 2003
Last sequence update: March 1, 2004
Last modified: February 15, 2017
This is version 108 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.