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Protein

Probable RNA-binding protein 23

Gene

RBM23

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at protein leveli

Functioni

Probable RNA-binding protein. May be involved in pre-mRNA splicing process.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Ligandi

RNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Probable RNA-binding protein 23
Alternative name(s):
RNA-binding motif protein 23
RNA-binding region-containing protein 4
Splicing factor SF2
Gene namesi
Name:RBM23
Synonyms:RNPC4
ORF Names:PP239
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 14

Organism-specific databases

HGNCiHGNC:20155. RBM23.

Subcellular locationi

GO - Cellular componenti

  • membrane Source: UniProtKB
  • nucleus Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Nucleus

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA134974852.

Polymorphism and mutation databases

BioMutaiRBM23.
DMDMi34925229.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 439439Probable RNA-binding protein 23PRO_0000081783Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei128 – 1281PhosphoserineCombined sources
Modified residuei149 – 1491PhosphoserineCombined sources

Keywords - PTMi

Phosphoprotein

Proteomic databases

EPDiQ86U06.
MaxQBiQ86U06.
PaxDbiQ86U06.
PeptideAtlasiQ86U06.
PRIDEiQ86U06.

PTM databases

iPTMnetiQ86U06.
PhosphoSiteiQ86U06.
SwissPalmiQ86U06.

Expressioni

Gene expression databases

BgeeiQ86U06.
CleanExiHS_RBM23.
ExpressionAtlasiQ86U06. baseline and differential.
GenevisibleiQ86U06. HS.

Organism-specific databases

HPAiHPA004144.

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
BHLHE40O145033EBI-10258579,EBI-711810
FAM9BQ8IZU03EBI-780319,EBI-10175124
MAGEA11P43364-23EBI-10258579,EBI-10178634
MAGED1Q9Y5V33EBI-780319,EBI-716006
PRMT5O147443EBI-780319,EBI-351098
SRPK2P783622EBI-780319,EBI-593303
TRIM27P143733EBI-780319,EBI-719493

Protein-protein interaction databases

BioGridi120450. 47 interactions.
IntActiQ86U06. 17 interactions.
MINTiMINT-1382566.
STRINGi9606.ENSP00000352956.

Structurei

Secondary structure

1
439
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Helixi162 – 1654Combined sources
Beta strandi167 – 1726Combined sources
Helixi179 – 1868Combined sources
Turni187 – 1893Combined sources
Beta strandi192 – 1976Combined sources
Beta strandi203 – 2053Combined sources
Beta strandi210 – 2156Combined sources
Helixi217 – 2193Combined sources
Helixi220 – 2267Combined sources
Beta strandi229 – 2313Combined sources
Beta strandi234 – 2407Combined sources
Helixi241 – 2488Combined sources
Beta strandi265 – 2695Combined sources
Helixi276 – 2838Combined sources
Turni284 – 2863Combined sources
Beta strandi289 – 2957Combined sources
Beta strandi298 – 3003Combined sources
Beta strandi305 – 3128Combined sources
Helixi314 – 32411Combined sources
Beta strandi329 – 3324Combined sources
Beta strandi335 – 3406Combined sources

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
2CQ4NMR-A148-248[»]
2DNZNMR-A265-346[»]
ProteinModelPortaliQ86U06.
SMRiQ86U06. Positions 150-347.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ86U06.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini166 – 24378RRM 1PROSITE-ProRule annotationAdd
BLAST
Domaini263 – 34179RRM 2PROSITE-ProRule annotationAdd
BLAST

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi63 – 12765Arg-richAdd
BLAST
Compositional biasi371 – 42454Ala-richAdd
BLAST

Sequence similaritiesi

Belongs to the splicing factor SR family.Curated
Contains 2 RRM (RNA recognition motif) domains.PROSITE-ProRule annotation

Keywords - Domaini

Repeat

Phylogenomic databases

eggNOGiKOG0147. Eukaryota.
ENOG410XP20. LUCA.
GeneTreeiENSGT00840000129750.
HOVERGENiHBG057646.
InParanoidiQ86U06.
OMAiKGTGGPM.
PhylomeDBiQ86U06.
TreeFamiTF320448.

Family and domain databases

Gene3Di3.30.70.330. 2 hits.
InterProiIPR012677. Nucleotide-bd_a/b_plait.
IPR029123. RBM39_linker.
IPR006509. RBM39_SF.
IPR000504. RRM_dom.
[Graphical view]
PfamiPF15519. RBM39linker. 1 hit.
PF00076. RRM_1. 2 hits.
[Graphical view]
SMARTiSM00360. RRM. 2 hits.
[Graphical view]
SUPFAMiSSF54928. SSF54928. 2 hits.
TIGRFAMsiTIGR01622. SF-CC1. 1 hit.
PROSITEiPS50102. RRM. 2 hits.
[Graphical view]

Sequences (5)i

Sequence statusi: Complete.

This entry describes 5 isoformsi produced by alternative splicing. AlignAdd to basket

Isoform 1 (identifier: Q86U06-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MASDDFDIVI EAMLEAPYKK EEDEQQRKEV KKDYPSNTTS STSNSGNETS
60 70 80 90 100
GSSTIGETSK KKRSRSHNKS RDRKRSRSRD RDRYRRRNSR SRSPGRQCRH
110 120 130 140 150
RSRSWDRRHG SESRSRDHRR EDRVHYRSPP LATGYRYGHS KSPHFREKSP
160 170 180 190 200
VREPVDNLSP EERDARTVFC MQLAARIRPR DLEDFFSAVG KVRDVRIISD
210 220 230 240 250
RNSRRSKGIA YVEFCEIQSV PLAIGLTGQR LLGVPIIVQA SQAEKNRLAA
260 270 280 290 300
MANNLQKGNG GPMRLYVGSL HFNITEDMLR GIFEPFGKID NIVLMKDSDT
310 320 330 340 350
GRSKGYGFIT FSDSECARRA LEQLNGFELA GRPMRVGHVT ERLDGGTDIT
360 370 380 390 400
FPDGDQELDL GSAGGRFQLM AKLAEGAGIQ LPSTAAAAAA AAAQAAALQL
410 420 430
NGAVPLGALN PAALTALSPA LNLASQCFQL SSLFTPQTM
Length:439
Mass (Da):48,731
Last modified:June 1, 2003 - v1
Checksum:iCFF3E56F7EA12D0B
GO
Isoform 2 (identifier: Q86U06-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     60-76: KKKRSRSHNKSRDRKRS → N

Show »
Length:423
Mass (Da):46,708
Checksum:i0DD858657398EC9C
GO
Isoform 3 (identifier: Q86U06-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     311-319: FSDSECARR → LHPPPLGTV
     320-439: Missing.

Show »
Length:319
Mass (Da):36,535
Checksum:i3983D6B0494B7EC8
GO
Isoform 4 (identifier: Q86U06-4) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     60-76: KKKRSRSHNKSRDRKRS → N
     135-152: Missing.

Show »
Length:405
Mass (Da):44,495
Checksum:i1344E0827F28B86D
GO
Isoform 5 (identifier: Q86U06-5) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-100: MASDDFDIVI...SRSPGRQCRH → MSNKGKKLKR...AEVQVGSVVT

Show »
Length:417
Mass (Da):44,930
Checksum:i88EB17EF60E117CB
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti132 – 1321A → T in AAG24388 (PubMed:14702039).Curated
Sequence conflicti321 – 33010LEQLNGFELA → CGTVEWGLSLL in AAP97203 (Ref. 1) Curated

Natural variant

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Natural varianti184 – 1841D → N.
Corresponds to variant rs34246954 [ dbSNP | Ensembl ].
VAR_052221
Natural varianti393 – 3931A → AA.4 Publications
VAR_016841
Natural varianti428 – 4281F → L.
Corresponds to variant rs1127066 [ dbSNP | Ensembl ].
VAR_052222

Alternative sequence

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Alternative sequencei1 – 100100MASDD…RQCRH → MSNKGKKLKRIILAIPPAAP ATVAMRPVEAAPSGRQARRR GVGAIIKAGIESAVVVEIGI GIDGEIVGAEVQVGSVVT in isoform 5. 1 PublicationVSP_008311Add
BLAST
Alternative sequencei60 – 7617KKKRS…DRKRS → N in isoform 2 and isoform 4. 3 PublicationsVSP_008312Add
BLAST
Alternative sequencei135 – 15218Missing in isoform 4. 1 PublicationVSP_008313Add
BLAST
Alternative sequencei311 – 3199FSDSECARR → LHPPPLGTV in isoform 3. 1 PublicationVSP_008314
Alternative sequencei320 – 439120Missing in isoform 3. 1 PublicationVSP_008315Add
BLAST

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF087905 mRNA. Translation: AAP97203.1.
AF275678 mRNA. Translation: AAG24388.1.
AK001344 mRNA. Translation: BAA91638.1.
AL834198 mRNA. Translation: CAD38887.1.
BX161440 mRNA. Translation: CAD61910.1.
AL132780 Genomic DNA. No translation available.
AL135998 Genomic DNA. No translation available.
CH471078 Genomic DNA. Translation: EAW66223.1.
CH471078 Genomic DNA. Translation: EAW66229.1.
BC002566 mRNA. Translation: AAH02566.1.
BC024208 mRNA. Translation: AAH24208.1.
CCDSiCCDS41919.1. [Q86U06-4]
CCDS41920.1. [Q86U06-2]
CCDS41921.1. [Q86U06-1]
RefSeqiNP_001070819.1. NM_001077351.1. [Q86U06-1]
NP_001070820.1. NM_001077352.1. [Q86U06-4]
NP_001294973.1. NM_001308044.1.
NP_060577.3. NM_018107.4. [Q86U06-2]
XP_011535200.1. XM_011536898.1. [Q86U06-1]
XP_011535201.1. XM_011536899.1. [Q86U06-2]
UniGeneiHs.4997.

Genome annotation databases

EnsembliENST00000346528; ENSP00000339220; ENSG00000100461. [Q86U06-4]
ENST00000359890; ENSP00000352956; ENSG00000100461. [Q86U06-1]
ENST00000399922; ENSP00000382806; ENSG00000100461. [Q86U06-2]
GeneIDi55147.
KEGGihsa:55147.
UCSCiuc001whg.4. human. [Q86U06-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF087905 mRNA. Translation: AAP97203.1.
AF275678 mRNA. Translation: AAG24388.1.
AK001344 mRNA. Translation: BAA91638.1.
AL834198 mRNA. Translation: CAD38887.1.
BX161440 mRNA. Translation: CAD61910.1.
AL132780 Genomic DNA. No translation available.
AL135998 Genomic DNA. No translation available.
CH471078 Genomic DNA. Translation: EAW66223.1.
CH471078 Genomic DNA. Translation: EAW66229.1.
BC002566 mRNA. Translation: AAH02566.1.
BC024208 mRNA. Translation: AAH24208.1.
CCDSiCCDS41919.1. [Q86U06-4]
CCDS41920.1. [Q86U06-2]
CCDS41921.1. [Q86U06-1]
RefSeqiNP_001070819.1. NM_001077351.1. [Q86U06-1]
NP_001070820.1. NM_001077352.1. [Q86U06-4]
NP_001294973.1. NM_001308044.1.
NP_060577.3. NM_018107.4. [Q86U06-2]
XP_011535200.1. XM_011536898.1. [Q86U06-1]
XP_011535201.1. XM_011536899.1. [Q86U06-2]
UniGeneiHs.4997.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
2CQ4NMR-A148-248[»]
2DNZNMR-A265-346[»]
ProteinModelPortaliQ86U06.
SMRiQ86U06. Positions 150-347.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi120450. 47 interactions.
IntActiQ86U06. 17 interactions.
MINTiMINT-1382566.
STRINGi9606.ENSP00000352956.

PTM databases

iPTMnetiQ86U06.
PhosphoSiteiQ86U06.
SwissPalmiQ86U06.

Polymorphism and mutation databases

BioMutaiRBM23.
DMDMi34925229.

Proteomic databases

EPDiQ86U06.
MaxQBiQ86U06.
PaxDbiQ86U06.
PeptideAtlasiQ86U06.
PRIDEiQ86U06.

Protocols and materials databases

DNASUi55147.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000346528; ENSP00000339220; ENSG00000100461. [Q86U06-4]
ENST00000359890; ENSP00000352956; ENSG00000100461. [Q86U06-1]
ENST00000399922; ENSP00000382806; ENSG00000100461. [Q86U06-2]
GeneIDi55147.
KEGGihsa:55147.
UCSCiuc001whg.4. human. [Q86U06-1]

Organism-specific databases

CTDi55147.
GeneCardsiRBM23.
HGNCiHGNC:20155. RBM23.
HPAiHPA004144.
neXtProtiNX_Q86U06.
PharmGKBiPA134974852.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG0147. Eukaryota.
ENOG410XP20. LUCA.
GeneTreeiENSGT00840000129750.
HOVERGENiHBG057646.
InParanoidiQ86U06.
OMAiKGTGGPM.
PhylomeDBiQ86U06.
TreeFamiTF320448.

Miscellaneous databases

ChiTaRSiRBM23. human.
EvolutionaryTraceiQ86U06.
GeneWikiiRBM23.
GenomeRNAii55147.
PROiQ86U06.

Gene expression databases

BgeeiQ86U06.
CleanExiHS_RBM23.
ExpressionAtlasiQ86U06. baseline and differential.
GenevisibleiQ86U06. HS.

Family and domain databases

Gene3Di3.30.70.330. 2 hits.
InterProiIPR012677. Nucleotide-bd_a/b_plait.
IPR029123. RBM39_linker.
IPR006509. RBM39_SF.
IPR000504. RRM_dom.
[Graphical view]
PfamiPF15519. RBM39linker. 1 hit.
PF00076. RRM_1. 2 hits.
[Graphical view]
SMARTiSM00360. RRM. 2 hits.
[Graphical view]
SUPFAMiSSF54928. SSF54928. 2 hits.
TIGRFAMsiTIGR01622. SF-CC1. 1 hit.
PROSITEiPS50102. RRM. 2 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Cloning and characterization of a new human cDNA homology to human splicing factor (CC1.3) mRNA."
    Yang J., Yu L., Zhou Y., Dai F.Y., Xin Y.R., Zhao S.Y.
    Submitted (AUG-1998) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2), VARIANT ALA-393 INS.
  2. "Large-scale cDNA transfection screening for genes related to cancer development and progression."
    Wan D., Gong Y., Qin W., Zhang P., Li J., Wei L., Zhou X., Li H., Qiu X., Zhong F., He L., Yu J., Yao G., Jiang H., Qian L., Yu Y., Shu H., Chen X.
    , Xu H., Guo M., Pan Z., Chen Y., Ge C., Yang S., Gu J.
    Proc. Natl. Acad. Sci. U.S.A. 101:15724-15729(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 5), VARIANT ALA-393 INS.
  3. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
    Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
    , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
    Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 4), VARIANT ALA-393 INS.
    Tissue: Neuron.
  4. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 3).
    Tissue: Brain.
  5. "Full-length cDNA libraries and normalization."
    Li W.B., Gruber C., Jessee J., Polayes D.
    Submitted (JAN-2003) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
    Tissue: Placenta.
  6. "The DNA sequence and analysis of human chromosome 14."
    Heilig R., Eckenberg R., Petit J.-L., Fonknechten N., Da Silva C., Cattolico L., Levy M., Barbe V., De Berardinis V., Ureta-Vidal A., Pelletier E., Vico V., Anthouard V., Rowen L., Madan A., Qin S., Sun H., Du H.
    , Pepin K., Artiguenave F., Robert C., Cruaud C., Bruels T., Jaillon O., Friedlander L., Samson G., Brottier P., Cure S., Segurens B., Aniere F., Samain S., Crespeau H., Abbasi N., Aiach N., Boscus D., Dickhoff R., Dors M., Dubois I., Friedman C., Gouyvenoux M., James R., Madan A., Mairey-Estrada B., Mangenot S., Martins N., Menard M., Oztas S., Ratcliffe A., Shaffer T., Trask B., Vacherie B., Bellemere C., Belser C., Besnard-Gonnet M., Bartol-Mavel D., Boutard M., Briez-Silla S., Combette S., Dufosse-Laurent V., Ferron C., Lechaplais C., Louesse C., Muselet D., Magdelenat G., Pateau E., Petit E., Sirvain-Trukniewicz P., Trybou A., Vega-Czarny N., Bataille E., Bluet E., Bordelais I., Dubois M., Dumont C., Guerin T., Haffray S., Hammadi R., Muanga J., Pellouin V., Robert D., Wunderle E., Gauguet G., Roy A., Sainte-Marthe L., Verdier J., Verdier-Discala C., Hillier L.W., Fulton L., McPherson J., Matsuda F., Wilson R., Scarpelli C., Gyapay G., Wincker P., Saurin W., Quetier F., Waterston R., Hood L., Weissenbach J.
    Nature 421:601-607(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  7. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  8. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2), VARIANT ALA-393 INS.
    Tissue: Muscle and Placenta.
  9. "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks."
    Olsen J.V., Blagoev B., Gnad F., Macek B., Kumar C., Mortensen P., Mann M.
    Cell 127:635-648(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-149, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Cervix carcinoma.
  10. "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."
    Mayya V., Lundgren D.H., Hwang S.-I., Rezaul K., Wu L., Eng J.K., Rodionov V., Han D.K.
    Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Leukemic T-cell.
  11. "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."
    Rigbolt K.T., Prokhorova T.A., Akimov V., Henningsen J., Johansen P.T., Kratchmarova I., Kassem M., Mann M., Olsen J.V., Blagoev B.
    Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-149, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  12. "Toward a comprehensive characterization of a human cancer cell phosphoproteome."
    Zhou H., Di Palma S., Preisinger C., Peng M., Polat A.N., Heck A.J., Mohammed S.
    J. Proteome Res. 12:260-271(2013) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-128 AND SER-149, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Cervix carcinoma and Erythroleukemia.
  13. "Solution structure of RNA binding domains in RNA binding motif protein 23."
    RIKEN structural genomics initiative (RSGI)
    Submitted (APR-2007) to the PDB data bank
    Cited for: STRUCTURE BY NMR OF 148-347.

Entry informationi

Entry nameiRBM23_HUMAN
AccessioniPrimary (citable) accession number: Q86U06
Secondary accession number(s): D3DS32
, Q8ND16, Q8TB88, Q8WY40, Q9BUJ1, Q9NVV7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 19, 2003
Last sequence update: June 1, 2003
Last modified: July 6, 2016
This is version 135 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. Human chromosome 14
    Human chromosome 14: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  5. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.