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Q86TZ7

- Q86TZ7_HUMAN

UniProt

Q86TZ7 - Q86TZ7_HUMAN

Protein
Submitted name:

Full-length cDNA clone CS0DI063YK23 of Placenta of Homo sapiens (human)

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 73 (01 Oct 2014)
      Sequence version 1 (01 Jun 2003)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. adenylate cyclase activity Source: InterPro
    2. nucleotide binding Source: UniProtKB-KW

    GO - Biological processi

    1. adenylate cyclase-modulating G-protein coupled receptor signaling pathway Source: Ensembl
    2. intracellular signal transduction Source: InterPro

    Keywords - Molecular functioni

    LyaseUniRule annotationSAAS annotation

    Keywords - Ligandi

    Nucleotide-bindingSAAS annotation

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Full-length cDNA clone CS0DI063YK23 of Placenta of Homo sapiens (human)Imported
    OrganismiHomo sapiens (Human)Imported
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

    Subcellular locationi

    GO - Cellular componenti

    1. dendrite Source: Ensembl
    2. integral component of membrane Source: InterPro
    3. intracellular Source: Ensembl

    PTM / Processingi

    Proteomic databases

    PRIDEiQ86TZ7.

    Expressioni

    Gene expression databases

    ArrayExpressiQ86TZ7.
    BgeeiQ86TZ7.

    Interactioni

    Structurei

    3D structure databases

    ProteinModelPortaliQ86TZ7.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.UniRule annotation

    Phylogenomic databases

    HOGENOMiHOG000006941.
    HOVERGENiHBG050458.
    KOiK08044.

    Family and domain databases

    Gene3Di3.30.70.1230. 2 hits.
    InterProiIPR001054. A/G_cyclase.
    IPR018297. A/G_cyclase_CS.
    IPR009398. Adenylate_cyclase-like.
    [Graphical view]
    PfamiPF06327. DUF1053. 1 hit.
    PF00211. Guanylate_cyc. 2 hits.
    [Graphical view]
    SMARTiSM00044. CYCc. 2 hits.
    [Graphical view]
    SUPFAMiSSF55073. SSF55073. 2 hits.
    PROSITEiPS00452. GUANYLATE_CYCLASE_1. 2 hits.
    PS50125. GUANYLATE_CYCLASE_2. 2 hits.
    [Graphical view]

    Sequencei

    Sequence statusi: Fragment.

    Q86TZ7-1 [UniParc]FASTAAdd to Basket

    « Hide

    SPAPSPDLAH SAAPAPRAPA PGLGAGEIMA RLFSPRPPPS EDLFYETYYS     50
    LSQQYPLLLL LLGIVLCALA ALLAVAWASG RELTSDPSFL TTVLCALGGF 100
    SLLLGLASRE QRLQRWTRPL SGLVWVALLA LGHAFLFTGG VVSAWDQVSY 150
    FLFVIFTAYA MLPLGMRDAA VAGLASSLSH LLVLGLYLGP QPDSRPALLP 200
    QLAANAVLFL CGNVAGVYHK ALMERALRAT FREALSSLHS RRRLDTEKKH 250
    QEHLLLSILP AYLAREMKAE IMARLQAGQG SRPESTNNFH SLYVKRHQGV 300
    SVLYADIVGF TRLASECSPK ELVLMLNELF GKFDQIAKEH ECMRIKILGD 350
    CYYCVSGLPL SLPDHAINCV RMGLDMCRAI RKLRAATGVD INMRVGVHSG 400
    SVLCGVIGLQ KWQYDVWSHD VTLANHMEAG GVPGRVHITG ATLALLAGAY 450
    AVEDAGMEHR DPYLRELGEP TYLVIDPRAE EEDEKGTAGG LLSSLEGLKM 500
    RPSLLMTRYL ESWGAAKPFA HLSHGDSPVS TSTPLPEKTL ASFSTQWSLD 550
    RSRTPRGLDD ELDTGDAKFF QVIEQLNSQK QWKQSKDFNP LTLYFREKEM 600
    EKEYRLSAIP AFKYYEACTF LVFLSNFIIQ MLVTNRPPAL AITYSITFLL 650
    FLLILFVCFS EDLMRCVLKG PKMLHWLPAL SGLVATRPGL RIALGTATIL 700
    LVFAMAITSL FFFPTSSDCP FQAPNVSSMI SNLSWELPGS LPLISVPYSM 750
    HCCTLGFLSC SLFLHMSFEL KLLLLLLWLA ASCSLFLHSH AWLSECLIVR 800
    LYLGPLDSRP GVLKEPKLMG AISFFIFFFT LLVLARQNEY YCRLDFLWKK 850
    KLRQEREETE TMENLTRLLL ENVLPAHVAP QFIGQNRRNE DLYHQSYECV 900
    CVLFASVPDF KEFYSESNIN HEGLECLRLL NEIIADFDEL LSKPKFSGVE 950
    KIKTIGSTYM AATGLNATSG QDAQQDAERS CSHLGTMVEF AVALGSKLDV 1000
    INKHSFNNFR LRVGLNHGPV VAGVIGAQKP QYDIWGNTVN VASRMESTGV 1050
    LGKIQVTEET AWALQSLGYT CYSRGVIKVK GKGQLCTYFL NTDLTRTGPP 1100
    SATLG 1105
    Length:1,105
    Mass (Da):122,352
    Last modified:June 1, 2003 - v1
    Checksum:i238E4973341EBCBB
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei1 – 11Imported

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BX248285 mRNA. Translation: CAD62613.1.
    RefSeqiNP_001185521.1. NM_001198592.1.
    UniGeneiHs.443428.

    Genome annotation databases

    GeneIDi196883.
    KEGGihsa:196883.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BX248285 mRNA. Translation: CAD62613.1 .
    RefSeqi NP_001185521.1. NM_001198592.1.
    UniGenei Hs.443428.

    3D structure databases

    ProteinModelPortali Q86TZ7.
    ModBasei Search...
    MobiDBi Search...

    Chemistry

    BindingDBi Q86TZ7.

    Proteomic databases

    PRIDEi Q86TZ7.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 196883.
    KEGGi hsa:196883.

    Organism-specific databases

    CTDi 196883.

    Phylogenomic databases

    HOGENOMi HOG000006941.
    HOVERGENi HBG050458.
    KOi K08044.

    Miscellaneous databases

    GenomeRNAii 196883.
    NextBioi 89574.

    Gene expression databases

    ArrayExpressi Q86TZ7.
    Bgeei Q86TZ7.

    Family and domain databases

    Gene3Di 3.30.70.1230. 2 hits.
    InterProi IPR001054. A/G_cyclase.
    IPR018297. A/G_cyclase_CS.
    IPR009398. Adenylate_cyclase-like.
    [Graphical view ]
    Pfami PF06327. DUF1053. 1 hit.
    PF00211. Guanylate_cyc. 2 hits.
    [Graphical view ]
    SMARTi SM00044. CYCc. 2 hits.
    [Graphical view ]
    SUPFAMi SSF55073. SSF55073. 2 hits.
    PROSITEi PS00452. GUANYLATE_CYCLASE_1. 2 hits.
    PS50125. GUANYLATE_CYCLASE_2. 2 hits.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Full-length cDNA libraries and normalization."
      Li W.B., Gruber C., Jessee J., Polayes D.
      Submitted (FEB-2003) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
      Tissue: PlacentaImported.
    2. Genoscope
      Submitted (FEB-2003) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
      Tissue: PlacentaImported.

    Entry informationi

    Entry nameiQ86TZ7_HUMAN
    AccessioniPrimary (citable) accession number: Q86TZ7
    Entry historyi
    Integrated into UniProtKB/TrEMBL: June 1, 2003
    Last sequence update: June 1, 2003
    Last modified: October 1, 2014
    This is version 73 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.