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Q86TQ8

- Q86TQ8_HUMAN

UniProt

Q86TQ8 - Q86TQ8_HUMAN

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Protein
Submitted name:

Dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex), isoform CRA_c

Gene

DLST

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. transferase activity, transferring acyl groups Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

TransferaseImported

Names & Taxonomyi

Protein namesi
Submitted name:
Dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex), isoform CRA_cImported
Submitted name:
Full-length cDNA 5-PRIME end of clone CS0DB006YE12 of Neuroblastoma of Homo sapiens (human)Imported
Gene namesi
Name:DLSTImported
ORF Names:hCG_22359Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Interactioni

Protein-protein interaction databases

MINTiMINT-1371207.

Structurei

3D structure databases

ProteinModelPortaliQ86TQ8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the 2-oxoacid dehydrogenase family.UniRule annotation

Phylogenomic databases

HOVERGENiHBG000268.

Family and domain databases

Gene3Di3.30.559.10. 1 hit.
InterProiIPR001078. 2-oxoacid_DH_actylTfrase.
IPR023213. CAT-like_dom.
IPR011053. Single_hybrid_motif.
[Graphical view]
PfamiPF00198. 2-oxoacid_dh. 1 hit.
[Graphical view]
SUPFAMiSSF51230. SSF51230. 1 hit.

Sequencei

Sequence statusi: Fragment.

Q86TQ8-1 [UniParc]FASTAAdd to Basket

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        10         20         30         40         50
MQMTWLQSKP QRLQNLSQRE MSGGRKVPSP ANGVIEALLV PDGGKVEGGT
60 70 80 90 100
PLFTLRKTGA APAKAKPAEA PAAAAPKAEP TAAAVPPPAA PIPTQMPPVP
110 120 130 140 150
SPSQPPSGKP VSAVKPTVAP PLAEPGAGKG LRSEHREKMN RMRQRIAQRL
160 170 180 190 200
KEAQNTCAML TTFNEIDMSN IQEMRARHKE AFLKKHNLKL GFMSAFVKAS
210 220 230 240 250
AFALQEQPVV NAVIDDTTKE VVYRDYIDIS VAVATPRGLV VPVIRNVEAM
260 270 280 290 300
NFADIERTIT ELGEKARKNE LAIEDMDGGT FTISNGGVFG SLFGTPIINP

PQSAILG
Length:307
Mass (Da):32,808
Last modified:June 1, 2003 - v1
Checksum:i29C5CDC4D003BEFA
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei307 – 3071Imported

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BX248764 mRNA. Translation: CAD66571.1.
CH471061 Genomic DNA. Translation: EAW81201.1.
UniGeneiHs.525459.

Genome annotation databases

UCSCiuc001xqu.2. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BX248764 mRNA. Translation: CAD66571.1 .
CH471061 Genomic DNA. Translation: EAW81201.1 .
UniGenei Hs.525459.

3D structure databases

ProteinModelPortali Q86TQ8.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

MINTi MINT-1371207.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

UCSCi uc001xqu.2. human.

Phylogenomic databases

HOVERGENi HBG000268.

Miscellaneous databases

ChiTaRSi DLST. human.

Family and domain databases

Gene3Di 3.30.559.10. 1 hit.
InterProi IPR001078. 2-oxoacid_DH_actylTfrase.
IPR023213. CAT-like_dom.
IPR011053. Single_hybrid_motif.
[Graphical view ]
Pfami PF00198. 2-oxoacid_dh. 1 hit.
[Graphical view ]
SUPFAMi SSF51230. SSF51230. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "The sequence of the human genome."
    Venter J.C., Adams M.D., Myers E.W., Li P.W., Mural R.J., Sutton G.G., Smith H.O., Yandell M., Evans C.A., Holt R.A., Gocayne J.D., Amanatides P., Ballew R.M., Huson D.H., Wortman J.R., Zhang Q., Kodira C.D., Zheng X.H.
    , Chen L., Skupski M., Subramanian G., Thomas P.D., Zhang J., Gabor Miklos G.L., Nelson C., Broder S., Clark A.G., Nadeau J., McKusick V.A., Zinder N., Levine A.J., Roberts R.J., Simon M., Slayman C., Hunkapiller M., Bolanos R., Delcher A., Dew I., Fasulo D., Flanigan M., Florea L., Halpern A., Hannenhalli S., Kravitz S., Levy S., Mobarry C., Reinert K., Remington K., Abu-Threideh J., Beasley E., Biddick K., Bonazzi V., Brandon R., Cargill M., Chandramouliswaran I., Charlab R., Chaturvedi K., Deng Z., Di Francesco V., Dunn P., Eilbeck K., Evangelista C., Gabrielian A.E., Gan W., Ge W., Gong F., Gu Z., Guan P., Heiman T.J., Higgins M.E., Ji R.R., Ke Z., Ketchum K.A., Lai Z., Lei Y., Li Z., Li J., Liang Y., Lin X., Lu F., Merkulov G.V., Milshina N., Moore H.M., Naik A.K., Narayan V.A., Neelam B., Nusskern D., Rusch D.B., Salzberg S., Shao W., Shue B., Sun J., Wang Z., Wang A., Wang X., Wang J., Wei M., Wides R., Xiao C., Yan C., Yao A., Ye J., Zhan M., Zhang W., Zhang H., Zhao Q., Zheng L., Zhong F., Zhong W., Zhu S., Zhao S., Gilbert D., Baumhueter S., Spier G., Carter C., Cravchik A., Woodage T., Ali F., An H., Awe A., Baldwin D., Baden H., Barnstead M., Barrow I., Beeson K., Busam D., Carver A., Center A., Cheng M.L., Curry L., Danaher S., Davenport L., Desilets R., Dietz S., Dodson K., Doup L., Ferriera S., Garg N., Gluecksmann A., Hart B., Haynes J., Haynes C., Heiner C., Hladun S., Hostin D., Houck J., Howland T., Ibegwam C., Johnson J., Kalush F., Kline L., Koduru S., Love A., Mann F., May D., McCawley S., McIntosh T., McMullen I., Moy M., Moy L., Murphy B., Nelson K., Pfannkoch C., Pratts E., Puri V., Qureshi H., Reardon M., Rodriguez R., Rogers Y.H., Romblad D., Ruhfel B., Scott R., Sitter C., Smallwood M., Stewart E., Strong R., Suh E., Thomas R., Tint N.N., Tse S., Vech C., Wang G., Wetter J., Williams S., Williams M., Windsor S., Winn-Deen E., Wolfe K., Zaveri J., Zaveri K., Abril J.F., Guigo R., Campbell M.J., Sjolander K.V., Karlak B., Kejariwal A., Mi H., Lazareva B., Hatton T., Narechania A., Diemer K., Muruganujan A., Guo N., Sato S., Bafna V., Istrail S., Lippert R., Schwartz R., Walenz B., Yooseph S., Allen D., Basu A., Baxendale J., Blick L., Caminha M., Carnes-Stine J., Caulk P., Chiang Y.H., Coyne M., Dahlke C., Mays A., Dombroski M., Donnelly M., Ely D., Esparham S., Fosler C., Gire H., Glanowski S., Glasser K., Glodek A., Gorokhov M., Graham K., Gropman B., Harris M., Heil J., Henderson S., Hoover J., Jennings D., Jordan C., Jordan J., Kasha J., Kagan L., Kraft C., Levitsky A., Lewis M., Liu X., Lopez J., Ma D., Majoros W., McDaniel J., Murphy S., Newman M., Nguyen T., Nguyen N., Nodell M., Pan S., Peck J., Peterson M., Rowe W., Sanders R., Scott J., Simpson M., Smith T., Sprague A., Stockwell T., Turner R., Venter E., Wang M., Wen M., Wu D., Wu M., Xia A., Zandieh A., Zhu X.
    Science 291:1304-1351(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
  2. "Full-length cDNA libraries and normalization."
    Li W.B., Gruber C., Jessee J., Polayes D.
    Submitted (FEB-2003) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: NeuroblastomaImported.
  3. Genoscope
    Submitted (FEB-2003) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: NeuroblastomaImported.
  4. Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiQ86TQ8_HUMAN
AccessioniPrimary (citable) accession number: Q86TQ8
Entry historyi
Integrated into UniProtKB/TrEMBL: June 1, 2003
Last sequence update: June 1, 2003
Last modified: October 29, 2014
This is version 76 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.