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Q86TL2

- TM110_HUMAN

UniProt

Q86TL2 - TM110_HUMAN

Protein

Transmembrane protein 110

Gene

TMEM110

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 1 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 69 (01 Oct 2014)
      Sequence version 1 (01 Jun 2003)
      Previous versions | rss
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    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Transmembrane protein 110
    Gene namesi
    Name:TMEM110
    OrganismiHomo sapiens (Human)
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 3

    Organism-specific databases

    HGNCiHGNC:30526. TMEM110.

    Subcellular locationi

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB-KW

    Keywords - Cellular componenti

    Membrane

    Pathology & Biotechi

    Organism-specific databases

    PharmGKBiPA142670761.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 294294Transmembrane protein 110PRO_0000243915Add
    BLAST

    Proteomic databases

    PaxDbiQ86TL2.
    PRIDEiQ86TL2.

    PTM databases

    PhosphoSiteiQ86TL2.

    Expressioni

    Gene expression databases

    BgeeiQ86TL2.
    CleanExiHS_TMEM110.
    GenevestigatoriQ86TL2.

    Organism-specific databases

    HPAiHPA051855.

    Interactioni

    Protein-protein interaction databases

    BioGridi131975. 1 interaction.

    Structurei

    3D structure databases

    ProteinModelPortaliQ86TL2.
    ModBaseiSearch...
    MobiDBiSearch...

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei29 – 4921HelicalSequence AnalysisAdd
    BLAST
    Transmembranei69 – 8921HelicalSequence AnalysisAdd
    BLAST
    Transmembranei102 – 12221HelicalSequence AnalysisAdd
    BLAST
    Transmembranei156 – 17621HelicalSequence AnalysisAdd
    BLAST
    Transmembranei194 – 21421HelicalSequence AnalysisAdd
    BLAST

    Family & Domainsi

    Keywords - Domaini

    Transmembrane, Transmembrane helix

    Phylogenomic databases

    eggNOGiNOG75442.
    HOGENOMiHOG000038493.
    HOVERGENiHBG059486.
    PhylomeDBiQ86TL2.
    TreeFamiTF324457.

    Family and domain databases

    InterProiIPR022127. DUF3661_TM.
    [Graphical view]
    PfamiPF12400. DUF3661. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q86TL2-1 [UniParc]FASTAAdd to Basket

    « Hide

    MQGPAGNASR GLPGGPPSTV ASGAGRCESG ALMHSFGIFL QGLLGVVAFS    50
    TLMLKRFREP KHERRPWRIW FLDTSKQAIG MLFIHFANVY LADLTEEDPC 100
    SLYLINFLLD ATVGMLLIYV GVRAVSVLVE WQQWESLRFG EYGDPLQCGA 150
    WVGQCALYIV IMIFEKSVVF IVLLILQWKK VALLNPIENP DLKLAIVMLI 200
    VPFFVNALMF WVVDNFLMRK GKTKAKLEER GANQDSRNGS KVRYRRAASH 250
    EESESEILIS ADDEMEESDV EEDLRRLTPL KPVKKKKHRF GLPV 294
    Length:294
    Mass (Da):33,187
    Last modified:June 1, 2003 - v1
    Checksum:i8B112BB1CB3478E0
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BC047015 mRNA. Translation: AAH47015.1.
    CCDSiCCDS2866.1.
    RefSeqiNP_940965.1. NM_198563.2.
    UniGeneiHs.744189.

    Genome annotation databases

    EnsembliENST00000355083; ENSP00000347195; ENSG00000213533.
    GeneIDi375346.
    KEGGihsa:375346.
    UCSCiuc003dgd.3. human.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BC047015 mRNA. Translation: AAH47015.1 .
    CCDSi CCDS2866.1.
    RefSeqi NP_940965.1. NM_198563.2.
    UniGenei Hs.744189.

    3D structure databases

    ProteinModelPortali Q86TL2.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 131975. 1 interaction.

    PTM databases

    PhosphoSitei Q86TL2.

    Proteomic databases

    PaxDbi Q86TL2.
    PRIDEi Q86TL2.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000355083 ; ENSP00000347195 ; ENSG00000213533 .
    GeneIDi 375346.
    KEGGi hsa:375346.
    UCSCi uc003dgd.3. human.

    Organism-specific databases

    CTDi 375346.
    GeneCardsi GC03M052870.
    HGNCi HGNC:30526. TMEM110.
    HPAi HPA051855.
    neXtProti NX_Q86TL2.
    PharmGKBi PA142670761.
    GenAtlasi Search...

    Phylogenomic databases

    eggNOGi NOG75442.
    HOGENOMi HOG000038493.
    HOVERGENi HBG059486.
    PhylomeDBi Q86TL2.
    TreeFami TF324457.

    Miscellaneous databases

    GenomeRNAii 375346.
    NextBioi 100495.
    PROi Q86TL2.

    Gene expression databases

    Bgeei Q86TL2.
    CleanExi HS_TMEM110.
    Genevestigatori Q86TL2.

    Family and domain databases

    InterProi IPR022127. DUF3661_TM.
    [Graphical view ]
    Pfami PF12400. DUF3661. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Tissue: Brain.

    Entry informationi

    Entry nameiTM110_HUMAN
    AccessioniPrimary (citable) accession number: Q86TL2
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: June 27, 2006
    Last sequence update: June 1, 2003
    Last modified: October 1, 2014
    This is version 69 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Human chromosome 3
      Human chromosome 3: entries, gene names and cross-references to MIM

    External Data

    Dasty 3