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Q86TL2 (TM110_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 68. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Transmembrane protein 110
Gene names
Name:TMEM110
OrganismHomo sapiens (Human) [Reference proteome]
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Protein attributes

Sequence length294 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Subcellular location

Membrane; Multi-pass membrane protein Potential.

Ontologies

Keywords
   Cellular componentMembrane
   DomainTransmembrane
Transmembrane helix
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Cellular_componentintegral component of membrane

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 294294Transmembrane protein 110
PRO_0000243915

Regions

Transmembrane29 – 4921Helical; Potential
Transmembrane69 – 8921Helical; Potential
Transmembrane102 – 12221Helical; Potential
Transmembrane156 – 17621Helical; Potential
Transmembrane194 – 21421Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
Q86TL2 [UniParc].

Last modified June 1, 2003. Version 1.
Checksum: 8B112BB1CB3478E0

FASTA29433,187
        10         20         30         40         50         60 
MQGPAGNASR GLPGGPPSTV ASGAGRCESG ALMHSFGIFL QGLLGVVAFS TLMLKRFREP 

        70         80         90        100        110        120 
KHERRPWRIW FLDTSKQAIG MLFIHFANVY LADLTEEDPC SLYLINFLLD ATVGMLLIYV 

       130        140        150        160        170        180 
GVRAVSVLVE WQQWESLRFG EYGDPLQCGA WVGQCALYIV IMIFEKSVVF IVLLILQWKK 

       190        200        210        220        230        240 
VALLNPIENP DLKLAIVMLI VPFFVNALMF WVVDNFLMRK GKTKAKLEER GANQDSRNGS 

       250        260        270        280        290 
KVRYRRAASH EESESEILIS ADDEMEESDV EEDLRRLTPL KPVKKKKHRF GLPV 

« Hide

References

[1]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Tissue: Brain.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BC047015 mRNA. Translation: AAH47015.1.
CCDSCCDS2866.1.
RefSeqNP_940965.1. NM_198563.2.
UniGeneHs.744189.

3D structure databases

ProteinModelPortalQ86TL2.
ModBaseSearch...
MobiDBSearch...

PTM databases

PhosphoSiteQ86TL2.

Proteomic databases

PaxDbQ86TL2.
PRIDEQ86TL2.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENST00000355083; ENSP00000347195; ENSG00000213533.
GeneID375346.
KEGGhsa:375346.
UCSCuc003dgd.3. human.

Organism-specific databases

CTD375346.
GeneCardsGC03M052870.
HGNCHGNC:30526. TMEM110.
HPAHPA051855.
neXtProtNX_Q86TL2.
PharmGKBPA142670761.
GenAtlasSearch...

Phylogenomic databases

eggNOGNOG75442.
HOGENOMHOG000038493.
HOVERGENHBG059486.
PhylomeDBQ86TL2.
TreeFamTF324457.

Gene expression databases

BgeeQ86TL2.
CleanExHS_TMEM110.
GenevestigatorQ86TL2.

Family and domain databases

InterProIPR022127. DUF3661_TM.
[Graphical view]
PfamPF12400. DUF3661. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

GenomeRNAi375346.
NextBio100495.
PROQ86TL2.

Entry information

Entry nameTM110_HUMAN
AccessionPrimary (citable) accession number: Q86TL2
Entry history
Integrated into UniProtKB/Swiss-Prot: June 27, 2006
Last sequence update: June 1, 2003
Last modified: July 9, 2014
This is version 68 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Relevant documents

Human chromosome 3

Human chromosome 3: entries, gene names and cross-references to MIM