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Protein
Submitted name:

SCUBE1 protein

Gene

SCUBE1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Ligandi

CalciumSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
SCUBE1 proteinImported
Gene namesi
Name:SCUBE1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 23Sequence analysisAdd BLAST23
ChainiPRO_500430092424 – 347Sequence analysisAdd BLAST324

Keywords - PTMi

Disulfide bondSAAS annotation

Expressioni

Gene expression databases

GenevisibleiQ86TI6. HS.

Structurei

3D structure databases

ProteinModelPortaliQ86TI6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini33 – 73EGF-likeInterPro annotationAdd BLAST41
Domaini74 – 116EGF-likeInterPro annotationAdd BLAST43
Domaini117 – 153EGF-likeInterPro annotationAdd BLAST37

Keywords - Domaini

EGF-like domainSAAS annotation, RepeatSAAS annotation, SignalSequence analysis

Phylogenomic databases

HOVERGENiHBG067450.

Family and domain databases

InterProiIPR001881. EGF-like_Ca-bd_dom.
IPR013032. EGF-like_CS.
IPR000742. EGF-like_dom.
IPR000152. EGF-type_Asp/Asn_hydroxyl_site.
IPR018097. EGF_Ca-bd_CS.
IPR024731. EGF_dom.
IPR009030. Growth_fac_rcpt_.
[Graphical view]
PfamiPF12947. EGF_3. 1 hit.
[Graphical view]
SMARTiSM00181. EGF. 6 hits.
SM00179. EGF_CA. 4 hits.
[Graphical view]
SUPFAMiSSF57184. SSF57184. 1 hit.
PROSITEiPS00010. ASX_HYDROXYL. 3 hits.
PS01186. EGF_2. 5 hits.
PS50026. EGF_3. 3 hits.
PS01187. EGF_CA. 3 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q86TI6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGAAAVRWHL CVLLALGTRG RLAGGSGLPG SVDVDECSEG TDDCHIDAIC
60 70 80 90 100
QNTPKSYKCL CKPGYKGEGK QCEDIDECEN DYYNGGCVHE CINIPGNYRC
110 120 130 140 150
TCFDGFMLAH DGHNCLDVDE CQDNNGGCQQ ICVNAMGSYE CQCHSGFFLS
160 170 180 190 200
DNQHTCIHRS NEGMNCMNKD HGCAHICRET PKGGVACDCR PGFDLAQNQK
210 220 230 240 250
DCTLTCNYGN GGCQHSCEDT DTGPTCGCHQ KYALHSDGRT CIEKDEAAIE
260 270 280 290 300
RSQFNATSVA DVDKRVKRRL LMETCAVNNG GCDRTCKDTA TGVRCSCPVG
310 320 330 340
FTLQPDGKTC KGQHVELCGC PCLYWPGQEP PCACIAGPRA GLSGGHV
Length:347
Mass (Da):37,279
Last modified:June 1, 2003 - v1
Checksum:iAEA284B29F3EC298
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC047916 mRNA. Translation: AAH47916.1.
RefSeqiNP_766638.2. NM_173050.3.
UniGeneiHs.133995.

Genome annotation databases

GeneIDi80274.
KEGGihsa:80274.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC047916 mRNA. Translation: AAH47916.1.
RefSeqiNP_766638.2. NM_173050.3.
UniGeneiHs.133995.

3D structure databases

ProteinModelPortaliQ86TI6.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

DNASUi80274.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi80274.
KEGGihsa:80274.

Organism-specific databases

CTDi80274.

Phylogenomic databases

HOVERGENiHBG067450.

Miscellaneous databases

GenomeRNAii80274.

Gene expression databases

GenevisibleiQ86TI6. HS.

Family and domain databases

InterProiIPR001881. EGF-like_Ca-bd_dom.
IPR013032. EGF-like_CS.
IPR000742. EGF-like_dom.
IPR000152. EGF-type_Asp/Asn_hydroxyl_site.
IPR018097. EGF_Ca-bd_CS.
IPR024731. EGF_dom.
IPR009030. Growth_fac_rcpt_.
[Graphical view]
PfamiPF12947. EGF_3. 1 hit.
[Graphical view]
SMARTiSM00181. EGF. 6 hits.
SM00179. EGF_CA. 4 hits.
[Graphical view]
SUPFAMiSSF57184. SSF57184. 1 hit.
PROSITEiPS00010. ASX_HYDROXYL. 3 hits.
PS01186. EGF_2. 5 hits.
PS50026. EGF_3. 3 hits.
PS01187. EGF_CA. 3 hits.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ86TI6_HUMAN
AccessioniPrimary (citable) accession number: Q86TI6
Entry historyi
Integrated into UniProtKB/TrEMBL: June 1, 2003
Last sequence update: June 1, 2003
Last modified: November 30, 2016
This is version 101 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.