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1 to 25 of 356  Show
  1. 1
    "Full-length cDNA libraries and normalization."
    Li W.B., Gruber C., Jessee J., Polayes D.
    Submitted (FEB-2003) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Category: Sequences.
    Tissue: Adult brain.
    Source: UniProtKB/TrEMBL (unreviewed).
  2. 2
    Genoscope
    Submitted (FEB-2003) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Category: Sequences.
    Tissue: Adult brain.
    Source: UniProtKB/TrEMBL (unreviewed).
  3. 3
    "A Nucleotide-dependent molecular switch controls ATP binding at the C-terminal domain of Hsp90. N-terminal nucleotide binding unmasks a C-terminal binding pocket."
    Soti C., Racz A., Csermely P.
    J. Biol. Chem. 277:7066-7075(2002) [PubMed] [Europe PMC] [Abstract]
    Annotation: Cisplatin may provide a pharmacological tool to dissect C- and N-terminal nucleotide binding of Hsp90. A model is proposed on the interactions of the two nucleotide-binding domains and the charged region of Hsp90.Imported.
    Source: GeneRIF:3320.

    This publication is mapped to 10 other entries.

  4. 4
    "Regulation of heat shock protein 90 ATPase activity by sequences in the carboxyl terminus."
    Owen B.A., Sullivan W.P., Felts S.J., Toft D.O.
    J. Biol. Chem. 277:7086-7091(2002) [PubMed] [Europe PMC] [Abstract]
    Annotation: These data indicate that sequences within the last one-fourth of hsp90 regulate ATP hydrolysisImported.
    Source: GeneRIF:3320.

    This publication is mapped to 9 other entries.

  5. 5
    "Involvement of Hsp90 in signaling and stability of 3-phosphoinositide-dependent kinase-1."
    Fujita N., Sato S., Ishida A., Tsuruo T.
    J. Biol. Chem. 277:10346-10353(2002) [PubMed] [Europe PMC] [Abstract]
    Annotation: association of PDK1 with Hsp90 regulates its stability solubility and signalingImported.
    Source: GeneRIF:3320.

    This publication is mapped to 14 other entries.

  6. 6
    "Two distinct regions of the immunophilin-like protein XAP2 regulate dioxin receptor function and interaction with hsp90."
    Kazlauskas A., Poellinger L., Pongratz I.
    J. Biol. Chem. 277:11795-11801(2002) [PubMed] [Europe PMC] [Abstract]
    Annotation: Two distinct regions of the immunophilin-like protein XAP2 regulate dioxin receptor function and interaction with hsp90Imported.
    Source: GeneRIF:3320.

    This publication is mapped to 41 other entries.

  7. 7
    "HSP40 binding is the first step in the HSP90 chaperoning pathway for the progesterone receptor."
    Hernandez M.P., Chadli A., Toft D.O.
    J. Biol. Chem. 277:11873-11881(2002) [PubMed] [Europe PMC] [Abstract]
    Annotation: HSP40 binding is the first step in the HSP90 chaperoning pathway for the progesterone receptorImported.
    Source: GeneRIF:3320.

    This publication is mapped to 14 other entries.

  8. 8
    "Molecular chaperones Hsp90 and Hsp70 deliver preproteins to the mitochondrial import receptor Tom70."
    Young J.C., Hoogenraad N.J., Hartl F.U.
    Cell 112:41-50(2003) [PubMed] [Europe PMC] [Abstract]
    Annotation: we show that in mammals the cytosolic chaperones Hsp90 and Hsp70 dock onto a specialized TPR domain in the import receptor Tom70 at the outer mitochondrial membrane.Imported.
    Source: GeneRIF:3320.

    This publication is mapped to 27 other entries.

  9. 9
    "Cofactor Tpr2 combines two TPR domains and a J domain to regulate the Hsp70/Hsp90 chaperone system."
    Brychzy A., Rein T., Winklhofer K.F., Hartl F.U., Young J.C., Obermann W.M.
    EMBO J. 22:3613-3623(2003) [PubMed] [Europe PMC] [Abstract]
    Annotation: TPR2 combines two TPR domains and a J domain to regulate the Hsp70/Hsp90 chaperone system.Imported.
    Source: GeneRIF:3320.

    This publication is cited by 3 and mapped to 11 other entries.

  10. 10
    "Heat shock protein 90 as an endogenous protein enhancer of inducible nitric-oxide synthase."
    Yoshida M., Xia Y.
    J. Biol. Chem. 278:36953-36958(2003) [PubMed] [Europe PMC] [Abstract]
    Annotation: Heat shock protein 90 is an endogenous protein enhancer of inducible nitric-oxide synthaseImported.
    Source: GeneRIF:3320.

    This publication is mapped to 24 other entries.

  11. 11
    "Translocation of N-WASP by nuclear localization and export signals into the nucleus modulates expression of HSP90."
    Suetsugu S., Takenawa T.
    J. Biol. Chem. 278:42515-42523(2003) [PubMed] [Europe PMC] [Abstract]
    Annotation: nuclear localization of N-WASP modulates Src kinase activity by regulating HSP90 expressionImported.
    Source: GeneRIF:3320.

    This publication is mapped to 12 other entries.

  12. 12
    "G protein-coupled receptor kinase interaction with Hsp90 mediates kinase maturation."
    Luo J., Benovic J.L.
    J. Biol. Chem. 278:50908-50914(2003) [PubMed] [Europe PMC] [Abstract]
    Annotation: GRK2 GRK3 GRK5 and GRK6 are stabilized by interaction with Hsp90 revealing that GRK interaction with heat shock proteins plays an important role in regulating GRK maturation.Imported.
    Source: GeneRIF:3320.

    This publication is mapped to 12 other entries.

  13. 13
    "Hsp90 inhibition depletes Chk1 and sensitizes tumor cells to replication stress."
    Arlander S.J., Eapen A.K., Vroman B.T., McDonald R.J., Toft D.O., Karnitz L.M.
    J. Biol. Chem. 278:52572-52577(2003) [PubMed] [Europe PMC] [Abstract]
    Annotation: HSP90 has a role in regulation of levels of Chk1 and sensitization of tumor cells to replication stressImported.
    Source: GeneRIF:3320.

    This publication is mapped to 12 other entries.

  14. 14
    "Regulation of survivin function by Hsp90."
    Fortugno P., Beltrami E., Plescia J., Fontana J., Pradhan D., Marchisio P.C., Sessa W.C., Altieri D.C.
    Proc. Natl. Acad. Sci. U.S.A. 100:13791-13796(2003) [PubMed] [Europe PMC] [Abstract]
    Annotation: Hsp90 a molecular chaperone that is central to the cellular stress response associates with survivin an apoptosis inhibitor and essential regulator of mitosis.Imported.
    Source: GeneRIF:3320.

    This publication is mapped to 18 other entries.

  15. 15
    "Stability of the Peutz-Jeghers syndrome kinase LKB1 requires its binding to the molecular chaperones Hsp90/Cdc37."
    Nony P., Gaude H., Rossel M., Fournier L., Rouault J.P., Billaud M.
    Oncogene 22:9165-9175(2003) [PubMed] [Europe PMC] [Abstract]
    Annotation: heteromeric complex containing the molecular chaperones Hsp90 and Cdc37/p50 interacts with the kinase domain of LKB1Imported.
    Source: GeneRIF:3320.

    This publication is mapped to 21 other entries.

  16. 16
    "Direct activation of HSP90A transcription by c-Myc contributes to c-Myc-induced transformation."
    Teng S.C., Chen Y.Y., Su Y.N., Chou P.C., Chiang Y.C., Tseng S.F., Wu K.J.
    J. Biol. Chem. 279:14649-14655(2004) [PubMed] [Europe PMC] [Abstract]
    Annotation: by induction of HSP90A c-Myc may control the activity of multiple signal pathways involved in cellular transformationImported.
    Source: GeneRIF:3320.

    This publication is mapped to 77 other entries.

  17. 17
    "Hsp90/p50cdc37 is required for mixed-lineage kinase (MLK) 3 signaling."
    Zhang H., Wu W., Du Y., Santos S.J., Conrad S.E., Watson J.T., Grammatikakis N., Gallo K.A.
    J. Biol. Chem. 279:19457-19463(2004) [PubMed] [Europe PMC] [Abstract]
    Annotation: Hsp90/p50cdc37 is required for mixed-lineage kinase (MLK) 3 signalingImported.
    Source: GeneRIF:3320.

    This publication is mapped to 18 other entries.

  18. 18
    "Induction of Hsp90 protein expression in malignant melanomas and melanoma metastases."
    Becker B., Multhoff G., Farkas B., Wild P.J., Landthaler M., Stolz W., Vogt T.
    Exp. Dermatol. 13:27-32(2004) [PubMed] [Europe PMC] [Abstract]
    Annotation: Hsp90 is expressed on the surface of tumor cells and is present in advanced malignant melanomas.Imported.
    Source: GeneRIF:3320.

    This publication is mapped to 8 other entries.

  19. 19
    "Retrograde transport of the glucocorticoid receptor in neurites requires dynamic assembly of complexes with the protein chaperone hsp90 and is linked to the CHIP component of the machinery for proteasomal degradation."
    Galigniana M.D., Harrell J.M., Housley P.R., Patterson C., Fisher S.K., Pratt W.B.
    Brain Res. Mol. Brain Res. 123:27-36(2004) [PubMed] [Europe PMC] [Abstract]
    Annotation: In neurites movement by diffusion is not possible and we show that movement of the GFP-Glucocorticoid Receptor from neurites is blocked by geldanamycin suggesting that the hsp90-dependent movement machinery is required for retrograde movement.Imported.
    Source: GeneRIF:3320.

    This publication is mapped to 9 other entries.

  20. 20
    "Regulation of nuclear retention of glucocorticoid receptor by nuclear Hsp90."
    Tago K., Tsukahara F., Naruse M., Yoshioka T., Takano K.
    Mol. Cell. Endocrinol. 213:131-138(2004) [PubMed] [Europe PMC] [Abstract]
    Annotation: the role of Hsp90 in nuclear retention of GR after ligand withdrawalImported.
    Source: GeneRIF:3320.

    This publication is mapped to 20 other entries.

  21. 21
    "The region adjacent to the highly immunogenic site and shielded by the middle domain is responsible for self-oligomerization/client binding of the HSP90 molecular chaperone."
    Nemoto T.K., Fukuma Y., Yamada S., Kobayakawa T., Ono T., Ohara-Nemoto Y.
    Biochemistry 43:7628-7636(2004) [PubMed] [Europe PMC] [Abstract]
    Annotation: the activation mechanism of HSP90 molecular chaperone that heat stress induces the liberation of the oligomerization/client-binding site of residues 311-350 by disrupting the intramolecular interaction between residues 289-389 and 401-546Imported.
    Source: GeneRIF:3320.

    This publication is mapped to 8 other entries.

  22. 22
    "Hsp90 chaperones wild-type p53 tumor suppressor protein."
    Walerych D., Kudla G., Gutkowska M., Wawrzynow B., Muller L., King F.W., Helwak A., Boros J., Zylicz A., Zylicz M.
    J. Biol. Chem. 279:48836-48845(2004) [PubMed] [Europe PMC] [Abstract]
    Annotation: Hsp90 chaperone activity is important for the transcriptional activity of genotypically wild-type p53Imported.
    Source: GeneRIF:3320.

    This publication is mapped to 150 other entries.

  23. 23
    "Hsp90 regulates the activity of wild type p53 under physiological and elevated temperatures."
    Mueller L., Schaupp A., Walerych D., Wegele H., Buchner J.
    J. Biol. Chem. 279:48846-48854(2004) [PubMed] [Europe PMC] [Abstract]
    Annotation: Hsp90 is required to maintain the folded active state of p53 by a reversible interactionImported.
    Source: GeneRIF:3320.

    This publication is mapped to 150 other entries.

  24. 24
    "Up-regulation of the association between heat shock protein 90 and endothelial nitric oxide synthase prevents high glucose-induced apoptosis in human endothelial cells."
    Lin L.Y., Lin C.Y., Ho F.M., Liau C.S.
    J. Cell. Biochem. 94:194-201(2005) [PubMed] [Europe PMC] [Abstract]
    Annotation: upregulation with ecNOS prevents apoptosis in endothelial cells induced by high glucoseImported.
    Source: GeneRIF:3320.

    This publication is mapped to 19 other entries.

  25. 25
    "Inhibition of adjuvant-induced arthritis by DNA vaccination with the 70-kd or the 90-kd human heat-shock protein: immune cross-regulation with the 60-kd heat-shock protein."
    Quintana F.J., Carmi P., Mor F., Cohen I.R.
    Arthritis Rheum. 50:3712-3720(2004) [PubMed] [Europe PMC] [Abstract]
    Annotation: T cell immunity to Hsp70 and Hsp90 like Hsp60-specific immunity can modulate arthritogenic response in adjuvant arthritis. Regulatory mechanisms induced by Hsp60 Hsp70 and Hsp90 are reinforced by an immune network that connects their reactivities.Imported.
    Source: GeneRIF:3320.

    This publication is mapped to 36 other entries.

1 to 25 of 356  Show