Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

CEL protein

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolaseSAAS annotation

Protein family/group databases

ESTHERihuman-CEL. Cholesterol_esterase.

Names & Taxonomyi

Protein namesi
Submitted name:
CEL proteinImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 23Sequence analysisAdd BLAST23
ChainiPRO_500732351224 – 722Sequence analysisAdd BLAST699

Proteomic databases

MaxQBiQ86SR3.
PeptideAtlasiQ86SR3.

Structurei

3D structure databases

ProteinModelPortaliQ86SR3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini29 – 544COesteraseInterPro annotationAdd BLAST516
Domaini557 – 639Mucin-likeInterPro annotationAdd BLAST83
Domaini619 – 715Mucin-likeInterPro annotationAdd BLAST97

Sequence similaritiesi

Belongs to the type-B carboxylesterase/lipase family.SAAS annotation

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiKOG1516. Eukaryota.
COG2272. LUCA.
HOVERGENiHBG008839.
KOiK12298.

Family and domain databases

Gene3Di3.40.50.1820. 1 hit.
InterProiView protein in InterPro
IPR029058. AB_hydrolase.
IPR033560. BAL.
IPR002018. CarbesteraseB.
IPR019826. Carboxylesterase_B_AS.
IPR019819. Carboxylesterase_B_CS.
IPR032059. Mucin-like.
PANTHERiPTHR43903:SF1. PTHR43903:SF1. 1 hit.
PfamiView protein in Pfam
PF00135. COesterase. 1 hit.
PF16058. Mucin-like. 2 hits.
SUPFAMiSSF53474. SSF53474. 1 hit.
PROSITEiView protein in PROSITE
PS00122. CARBOXYLESTERASE_B_1. 1 hit.
PS00941. CARBOXYLESTERASE_B_2. 1 hit.

Sequencei

Sequence statusi: Complete.

Q86SR3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLTMGRLQLV VLGLTCCWAV ASAAKLGAVY TEGGFVEGVN KKLGLLGDSV
60 70 80 90 100
DIFKGIPFAA PTKALENPQP HPGWQGTLKA KNFKKRCLQA TITQDSTYGD
110 120 130 140 150
EDCLYLNIWV PQGRKQVSRD LPVMIWIYGG AFLMGSGHGA NFLNNYLYDG
160 170 180 190 200
EEIATRGNVI VVTFNYRVGP LGFLSTGDAN LPGNYGLRDQ HMAIAWVKRN
210 220 230 240 250
IAAFGGDPNN ITLFGESAGG ASVSLQTLSP YNKGLIRRAI SQSGVALSPW
260 270 280 290 300
VIQKNPLFWA KKVAEKVGCP VGDAARMAQC LKVTDPRALT LAYKVPLAGL
310 320 330 340 350
EYPMLHYVGF VPVIDGDFIP ADPINLYANA ADIDYIAGTN NMDGHIFASI
360 370 380 390 400
DMPAINKGNK KVTEDFYKLV SEFTITKGLR GAKTTFDVYT ESWAQDPSQE
410 420 430 440 450
NKKKTVVDFE TDVLFLVPTE IALAQHRANA KSAKTYAYLF SHPSRMPVYP
460 470 480 490 500
KWVGADHADD IQYVFGKPFA TPTGYRPQDR TVSKAMIAYW TNFAKTGDPN
510 520 530 540 550
MGDSAVPTHW EPYTTENSGY LEITKKMGSS SMKRSLRTNF LRYWTLTYLA
560 570 580 590 600
LPTVTDQEAT PVPPTGDSEA TPVPPTGDSE TAPVPPTGDS GAPPVPPTGD
610 620 630 640 650
SGAPPVPPTG DSGAPPVPPT GDSGAPPVPP TGDSGAPPVP PTGDAGPPPV
660 670 680 690 700
PPTGDSGAPP VPPTGDSGAP PVTPTGDSET APVPPTGDSG APPVPPTGDS
710 720
EAAPVPPTDD SKEAQMPAVI RF
Length:722
Mass (Da):76,610
Last modified:June 1, 2003 - v1
Checksum:i8AA686E4CF02928B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC042510 mRNA. Translation: AAH42510.1.
RefSeqiNP_001798.2. NM_001807.4.
UniGeneiHs.533258.

Genome annotation databases

GeneIDi1056.
KEGGihsa:1056.

Similar proteinsi

Entry informationi

Entry nameiQ86SR3_HUMAN
AccessioniPrimary (citable) accession number: Q86SR3
Entry historyiIntegrated into UniProtKB/TrEMBL: June 1, 2003
Last sequence update: June 1, 2003
Last modified: February 28, 2018
This is version 96 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.