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Protein

Probable GH family 25 lysozyme 2

Gene

DDB_G0274181

Organism
Dictyostelium discoideum (Slime mold)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei114By similarity1

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Antimicrobial, Bacteriolytic enzyme, Glycosidase, Hydrolase

Names & Taxonomyi

Protein namesi
Recommended name:
Probable GH family 25 lysozyme 2 (EC:3.2.1.17)
Alternative name(s):
1,4-beta-N-acetylmuramidase 2
Gene namesi
ORF Names:DDB_G0274181
OrganismiDictyostelium discoideum (Slime mold)
Taxonomic identifieri44689 [NCBI]
Taxonomic lineageiEukaryotaAmoebozoaMycetozoaDictyosteliidaDictyostelium
Proteomesi
  • UP000002195 Componentsi: Chromosome 2, Unassembled WGS sequence

Organism-specific databases

dictyBaseiDDB_G0274181.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 19Sequence analysisAdd BLAST19
ChainiPRO_000033064820 – 212Probable GH family 25 lysozyme 2Add BLAST193

Proteomic databases

PaxDbiQ86KC1.

Structurei

3D structure databases

ProteinModelPortaliQ86KC1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the glycosyl hydrolase 25 family.Curated

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiENOG410IZBF. Eukaryota.
ENOG41124VU. LUCA.
InParanoidiQ86KC1.
OMAiHQWHGTE.
PhylomeDBiQ86KC1.

Family and domain databases

Gene3Di3.20.20.80. 1 hit.
InterProiIPR002053. Glyco_hydro_25.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PfamiPF01183. Glyco_hydro_25. 1 hit.
[Graphical view]
SUPFAMiSSF51445. SSF51445. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q86KC1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRFIALLISF FALLKVISAI SGVDISSAST IESFTCLKSA GYDFAIIRAY
60 70 80 90 100
ESLGQVDPNG PHSVYNARDA GIEYVDVYMF PCPTCGNGAG QAETMVNYLK
110 120 130 140 150
GYNANYGMVW LDIEGPQYWM SQSENVAFFE SLVAGLKAEG AHIGVYTSAS
160 170 180 190 200
QWEPIMGGYT GGSEFPLWYA HYDGNPSFSD FSPFNGWSTP SVKQYDDTGD
210
SCGLGFDLNW YP
Length:212
Mass (Da):23,202
Last modified:June 1, 2003 - v1
Checksum:iB6036D806E5E8281
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAFI02000012 Genomic DNA. Translation: EAL69983.1.
RefSeqiXP_644284.1. XM_639192.1.

Genome annotation databases

EnsemblProtistsiEAL69983; EAL69983; DDB_G0274181.
GeneIDi8619712.
KEGGiddi:DDB_G0274181.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAFI02000012 Genomic DNA. Translation: EAL69983.1.
RefSeqiXP_644284.1. XM_639192.1.

3D structure databases

ProteinModelPortaliQ86KC1.
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PaxDbiQ86KC1.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblProtistsiEAL69983; EAL69983; DDB_G0274181.
GeneIDi8619712.
KEGGiddi:DDB_G0274181.

Organism-specific databases

dictyBaseiDDB_G0274181.

Phylogenomic databases

eggNOGiENOG410IZBF. Eukaryota.
ENOG41124VU. LUCA.
InParanoidiQ86KC1.
OMAiHQWHGTE.
PhylomeDBiQ86KC1.

Miscellaneous databases

PROiQ86KC1.

Family and domain databases

Gene3Di3.20.20.80. 1 hit.
InterProiIPR002053. Glyco_hydro_25.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PfamiPF01183. Glyco_hydro_25. 1 hit.
[Graphical view]
SUPFAMiSSF51445. SSF51445. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiLYSG2_DICDI
AccessioniPrimary (citable) accession number: Q86KC1
Secondary accession number(s): Q554N9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 29, 2008
Last sequence update: June 1, 2003
Last modified: November 2, 2016
This is version 68 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Dictyostelium discoideum
    Dictyostelium discoideum: entries, gene names and cross-references to dictyBase
  2. Glycosyl hydrolases
    Classification of glycosyl hydrolase families and list of entries
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.