Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q86J12

- HAT11_DICDI

UniProt

Q86J12 - HAT11_DICDI

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Histone acetyltransferase type B catalytic subunit DDB_G0274269

Gene

DDB_G0274269

Organism
Dictyostelium discoideum (Slime mold)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

Acetyl-CoA + [histone] = CoA + acetyl-[histone].By similarity

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sitei218 – 2181Interaction with histone H4 N-terminusBy similarity
Active sitei299 – 2991Proton donor/acceptorBy similarity

GO - Molecular functioni

  1. histone acetyltransferase activity Source: UniProtKB-EC

GO - Biological processi

  1. chromatin silencing at telomere Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Acyltransferase, Transferase

Names & Taxonomyi

Protein namesi
Recommended name:
Histone acetyltransferase type B catalytic subunit DDB_G0274269 (EC:2.3.1.48By similarity)
Gene namesi
ORF Names:DDB_G0274269
OrganismiDictyostelium discoideum (Slime mold)
Taxonomic identifieri44689 [NCBI]
Taxonomic lineageiEukaryotaAmoebozoaMycetozoaDictyosteliidaDictyostelium
ProteomesiUP000002195: Chromosome 2, UP000002195: Unassembled WGS sequence

Organism-specific databases

dictyBaseiDDB_G0274269.

Subcellular locationi

GO - Cellular componenti

  1. nucleus Source: InterPro
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 486486Histone acetyltransferase type B catalytic subunit DDB_G0274269PRO_0000367831Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi44689.DDBDRAFT_0167844.

Structurei

3D structure databases

ProteinModelPortaliQ86J12.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini189 – 386198N-acetyltransferaseAdd
BLAST

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni260 – 2623Acetyl-CoA bindingBy similarity
Regioni267 – 2737Acetyl-CoA bindingBy similarity

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili27 – 6943Sequence AnalysisAdd
BLAST
Coiled coili392 – 48190Sequence AnalysisAdd
BLAST

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi51 – 566Poly-Glu
Compositional biasi62 – 676Poly-Glu

Sequence similaritiesi

Belongs to the HAT1 family.Curated
Contains 1 N-acetyltransferase domain.Curated

Keywords - Domaini

Coiled coil

Phylogenomic databases

eggNOGiNOG326277.
InParanoidiQ86J12.
KOiK11303.
PhylomeDBiQ86J12.

Family and domain databases

Gene3Di3.40.630.30. 1 hit.
3.90.360.10. 2 hits.
InterProiIPR016181. Acyl_CoA_acyltransferase.
IPR019467. Hat1_N.
IPR017380. Hist_AcTrfase_B-typ_cat-su.
[Graphical view]
PANTHERiPTHR12046. PTHR12046. 1 hit.
PfamiPF10394. Hat1_N. 1 hit.
[Graphical view]
PIRSFiPIRSF038084. HAT-B_cat. 1 hit.
SUPFAMiSSF55729. SSF55729. 2 hits.

Sequencei

Sequence statusi: Complete.

Q86J12-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MTNRIKSSNT LLTFDANEVT NIKLVWDIEE LKNKDNKENK DKENKAHIKD
60 70 80 90 100
EGEEEEQKEK KEEEEKEDDG GPISFHPTYS HQIFNEDKIQ GYEPCKIDIY
110 120 130 140 150
MGAGSLTSYI DTNYTLQSKN LTNVEGEFLK VFSKQDPPIS KQSFYKYIEE
160 170 180 190 200
KEKLFKPIGK KIHEYSIIDK ESGKETEYEI YFGRITDQVV FRYHEKLQIF
210 220 230 240 250
VLWYIDGSSY IWTDDPNWDI FFIFEKRIID GEKRYGITGY STIYNFYHHP
260 270 280 290 300
EQTRARISQY LILPPYQRMG HGKYLFNSIY QYYKTNDGFY GPIYDITIED
310 320 330 340 350
PADEFNLLRN YVDLKNIMDE KLFDNVILDL NANNKSVFEE IRKKLLIPYK
360 370 380 390 400
QSKLCLEIYL FSKFLGTPNS DTKYKEYRIS IKKRLYKQNI GDSEQIEKIK
410 420 430 440 450
QQVAEENQEN LRLEQEELQE LQDIENKKNG TNIKVDIKPK ELTTPPGPEK
460 470 480
NKEEIEKDRL EEILELYKEL EKNYHKTLSS LNLISK
Length:486
Mass (Da):57,832
Last modified:June 1, 2003 - v1
Checksum:iB47394CB3F8294E7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAFI02000012 Genomic DNA. Translation: EAL70027.1.
RefSeqiXP_643973.1. XM_638881.1.

Genome annotation databases

EnsemblProtistsiDDB0237834; DDB0237834; DDB_G0274269.
GeneIDi8619399.
KEGGiddi:DDB_G0274269.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAFI02000012 Genomic DNA. Translation: EAL70027.1 .
RefSeqi XP_643973.1. XM_638881.1.

3D structure databases

ProteinModelPortali Q86J12.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 44689.DDBDRAFT_0167844.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblProtistsi DDB0237834 ; DDB0237834 ; DDB_G0274269 .
GeneIDi 8619399.
KEGGi ddi:DDB_G0274269.

Organism-specific databases

dictyBasei DDB_G0274269.

Phylogenomic databases

eggNOGi NOG326277.
InParanoidi Q86J12.
KOi K11303.
PhylomeDBi Q86J12.

Family and domain databases

Gene3Di 3.40.630.30. 1 hit.
3.90.360.10. 2 hits.
InterProi IPR016181. Acyl_CoA_acyltransferase.
IPR019467. Hat1_N.
IPR017380. Hist_AcTrfase_B-typ_cat-su.
[Graphical view ]
PANTHERi PTHR12046. PTHR12046. 1 hit.
Pfami PF10394. Hat1_N. 1 hit.
[Graphical view ]
PIRSFi PIRSF038084. HAT-B_cat. 1 hit.
SUPFAMi SSF55729. SSF55729. 2 hits.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: AX4.
  2. "The genome of the social amoeba Dictyostelium discoideum."
    Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R., Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B., Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T., Lehmann R., Hamlin N.
    , Davies R., Gaudet P., Fey P., Pilcher K., Chen G., Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N., Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E., Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N., Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D., Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T., Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D., Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A., Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M., Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A., Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y., Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C., Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R., Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.
    Nature 435:43-57(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: AX4.

Entry informationi

Entry nameiHAT11_DICDI
AccessioniPrimary (citable) accession number: Q86J12
Secondary accession number(s): Q555T7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: June 1, 2003
Last modified: October 29, 2014
This is version 59 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Dictyostelium discoideum
    Dictyostelium discoideum: entries, gene names and cross-references to dictyBase
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3