Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

Q86J12 (HAT11_DICDI) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 54. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Histone acetyltransferase type B catalytic subunit DDB_G0274269

EC=2.3.1.48
Gene names
ORF Names:DDB_G0274269
OrganismDictyostelium discoideum (Slime mold) [Reference proteome]
Taxonomic identifier44689 [NCBI]
Taxonomic lineageEukaryotaAmoebozoaMycetozoaDictyosteliidaDictyostelium

Protein attributes

Sequence length486 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Acetyl-CoA + [histone] = CoA + acetyl-[histone].

Sequence similarities

Belongs to the HAT1 family.

Contains 1 N-acetyltransferase domain.

Ontologies

Keywords
   DomainCoiled coil
   Molecular functionAcyltransferase
Transferase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processchromatin silencing at telomere

Inferred from electronic annotation. Source: InterPro

   Cellular_componentnucleus

Inferred from electronic annotation. Source: InterPro

   Molecular_functionhistone acetyltransferase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 486486Histone acetyltransferase type B catalytic subunit DDB_G0274269
PRO_0000367831

Regions

Domain189 – 386198N-acetyltransferase
Coiled coil27 – 6943 Potential
Coiled coil392 – 48190 Potential
Compositional bias51 – 566Poly-Glu
Compositional bias62 – 676Poly-Glu

Sequences

Sequence LengthMass (Da)Tools
Q86J12 [UniParc].

Last modified June 1, 2003. Version 1.
Checksum: B47394CB3F8294E7

FASTA48657,832
        10         20         30         40         50         60 
MTNRIKSSNT LLTFDANEVT NIKLVWDIEE LKNKDNKENK DKENKAHIKD EGEEEEQKEK 

        70         80         90        100        110        120 
KEEEEKEDDG GPISFHPTYS HQIFNEDKIQ GYEPCKIDIY MGAGSLTSYI DTNYTLQSKN 

       130        140        150        160        170        180 
LTNVEGEFLK VFSKQDPPIS KQSFYKYIEE KEKLFKPIGK KIHEYSIIDK ESGKETEYEI 

       190        200        210        220        230        240 
YFGRITDQVV FRYHEKLQIF VLWYIDGSSY IWTDDPNWDI FFIFEKRIID GEKRYGITGY 

       250        260        270        280        290        300 
STIYNFYHHP EQTRARISQY LILPPYQRMG HGKYLFNSIY QYYKTNDGFY GPIYDITIED 

       310        320        330        340        350        360 
PADEFNLLRN YVDLKNIMDE KLFDNVILDL NANNKSVFEE IRKKLLIPYK QSKLCLEIYL 

       370        380        390        400        410        420 
FSKFLGTPNS DTKYKEYRIS IKKRLYKQNI GDSEQIEKIK QQVAEENQEN LRLEQEELQE 

       430        440        450        460        470        480 
LQDIENKKNG TNIKVDIKPK ELTTPPGPEK NKEEIEKDRL EEILELYKEL EKNYHKTLSS 


LNLISK 

« Hide

References

[1]"Sequence and analysis of chromosome 2 of Dictyostelium discoideum."
Gloeckner G., Eichinger L., Szafranski K., Pachebat J.A., Bankier A.T., Dear P.H., Lehmann R., Baumgart C., Parra G., Abril J.F., Guigo R., Kumpf K., Tunggal B., Cox E.C., Quail M.A., Platzer M., Rosenthal A., Noegel A.A.
Nature 418:79-85(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: AX4.
[2]"The genome of the social amoeba Dictyostelium discoideum."
Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R., Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B., Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T., Lehmann R., Hamlin N. expand/collapse author list , Davies R., Gaudet P., Fey P., Pilcher K., Chen G., Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N., Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E., Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N., Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D., Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T., Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D., Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A., Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M., Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A., Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y., Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C., Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R., Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.
Nature 435:43-57(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: AX4.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AAFI02000012 Genomic DNA. Translation: EAL70027.1.

3D structure databases

ProteinModelPortalQ86J12.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING44689.DDBDRAFT_0167844.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblProtistsDDB0237834; DDB0237834; DDB_G0274269.
KEGGddi:DDB_G0274269.

Organism-specific databases

dictyBaseDDB_G0274269.

Phylogenomic databases

eggNOGNOG326277.
KOK11303.
PhylomeDBQ86J12.
ProtClustDBCLSZ2430988.

Family and domain databases

Gene3D3.40.630.30. 1 hit.
3.90.360.10. 2 hits.
InterProIPR016181. Acyl_CoA_acyltransferase.
IPR019467. Hat1_N.
IPR017380. Hist_AcTrfase_B-typ_cat-su.
[Graphical view]
PANTHERPTHR12046. PTHR12046. 1 hit.
PfamPF10394. Hat1_N. 1 hit.
[Graphical view]
PIRSFPIRSF038084. HAT-B_cat. 1 hit.
SUPFAMSSF55729. SSF55729. 2 hits.
ProtoNetSearch...

Entry information

Entry nameHAT11_DICDI
AccessionPrimary (citable) accession number: Q86J12
Secondary accession number(s): Q555T7
Entry history
Integrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: June 1, 2003
Last modified: April 16, 2014
This is version 54 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)

Relevant documents

SIMILARITY comments

Index of protein domains and families

Dictyostelium discoideum

Dictyostelium discoideum: entries, gene names and cross-references to dictyBase