Q86C62 (Q86C62_DROME) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
ETHR, isoform B EMBL AAS65191.1

Submitted name:
Putative ETH receptor splicing variant b EMBL AAO74887.1

Gene names

Name:	ETHR FlyBase FBgn0038874 EMBL AAS65191.1
ORF Names:	CG5911 FlyBase FBgn0038874, Dmel_CG5911 EMBL AAS65191.1

Organism

Drosophila melanogaster (Fruit fly) EMBL AAO74887.1

Taxonomic identifier

7227 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora

Protein attributes

Sequence length	461 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Sequence similarities

Belongs to the G-protein coupled receptor 1 family. RuleBase RU000688

Ontologies

Keywords
Cellular component	Membrane
Domain	Transmembrane RuleBase RU000688
Molecular function	G-protein coupled receptor RuleBase RU000688 Receptor Transducer
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Cellular component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	ecdysis-triggering hormone receptor activity Inferred from direct assay Ref.3. Source: FlyBase
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q86C62 [UniParc]. Last modified June 1, 2003. Version 1. Checksum: BFEF89E4901831E6	FASTA	461	50,672
	10 20 30 40 50 60 MLPQIPSYIR TTAMFFCIVI MLLGVVGNVM VPIVIVKTKD MRNSTNIFLT NLSIADLLVL 70 80 90 100 110 120 LVCTPTVLVE VNTRPETWVL GHEMCKAVPF VELTVAHASV LTILAISFER YYAICEPLKA 130 140 150 160 170 180 GYVCTKGRAI LICVLAWGIA ALFTSPIIAI STYSVEPYGD GTDAPVCTTA ADGFWSIFYF 190 200 210 220 230 240 VGCITVFFFL PFGILVLLYA AIAYKLLRPN NAFHRPTSPQ PQQPSGGATS GSSQVPSTKG 250 260 270 280 290 300 NSHQQSNGMR KHRKQVIFML VAVVSSFFVC LLPFRAFTLW VILASAEDVE GLGIAGYYNL 310 320 330 340 350 360 LYFSRFMLYL NSAMNPILYN LMSSKFRSGF WRLLLTCLGQ RPHHHHRHHY HQRQHPTAGG 370 380 390 400 410 420 SGRNASTRQE QDAEEGAALA GTTSARHPRR TLRREATFLI NSISTSSGTD RTTSSSAWRS 430 440 450 460 NSLSISGLSE RERGILGAAI IGTTAATVTT ACLQERRASK I

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The genome sequence of Drosophila melanogaster." Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D., Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F., George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N., Sutton G.G., Wortman J.R., Yandell M.D. , Zhang Q., Chen L.X., Brandon R.C., Rogers Y.H., Blazej R.G., Champe M., Pfeiffer B.D., Wan K.H., Doyle C., Baxter E.G., Helt G., Nelson C.R., Gabor G.L., Abril J.F., Agbayani A., An H.J., Andrews-Pfannkoch C., Baldwin D., Ballew R.M., Basu A., Baxendale J., Bayraktaroglu L., Beasley E.M., Beeson K.Y., Benos P.V., Berman B.P., Bhandari D., Bolshakov S., Borkova D., Botchan M.R., Bouck J., Brokstein P., Brottier P., Burtis K.C., Busam D.A., Butler H., Cadieu E., Center A., Chandra I., Cherry J.M., Cawley S., Dahlke C., Davenport L.B., Davies P., de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I., Dietz S.M., Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C., Dunn P., Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S., Fleischmann W., Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M., Glasser K., Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M., Harris N.L., Harvey D., Heiman T.J., Hernandez J.R., Houck J., Hostin D., Houston K.A., Howland T.J., Wei M.H., Ibegwam C., Jalali M., Kalush F., Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., Kimmel B.E., Kodira C.D., Kraft C., Kravitz S., Kulp D., Lai Z., Lasko P., Lei Y., Levitsky A.A., Li J., Li Z., Liang Y., Lin X., Liu X., Mattei B., McIntosh T.C., McLeod M.P., McPherson D., Merkulov G., Milshina N.V., Mobarry C., Morris J., Moshrefi A., Mount S.M., Moy M., Murphy B., Murphy L., Muzny D.M., Nelson D.L., Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R., Pacleb J.M., Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V., Reese M.G., Reinert K., Remington K., Saunders R.D., Scheeler F., Shen H., Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T., Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., Svirskas R., Tector C., Turner R., Venter E., Wang A.H., Wang X., Wang Z.Y., Wassarman D.A., Weinstock G.M., Weissenbach J., Williams S.M., WoodageT, Worley K.C., Wu D., Yang S., Yao Q.A., Ye J., Yeh R.F., Zaveri J.S., Zhan M., Zhang G., Zhao Q., Zheng L., Zheng X.H., Zhong F.N., Zhong W., Zhou X., Zhu S., Zhu X., Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M., Venter J.C. Science 287:2185-2195(2000) [PubMed: 10731132] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Berkeley.
[2]	"Annotation of the Drosophila melanogaster euchromatic genome: a systematic review." Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S., Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E., Smith C.D., Tupy J.L., Whitfield E.J., Bayraktaroglu L., Berman B.P., Bettencourt B.R., Celniker S.E., de Grey A.D.N.J. , Drysdale R.A., Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q., Stapleton M., Yamada C., Ashburner M., Gelbart W.M., Rubin G.M., Lewis S.E. Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002) [PubMed: 12537572] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: Berkeley.
[3]	"Two subtypes of ecdysis-triggering hormone receptor in Drosophila melanogaster." Park Y., Kim Y.J., Dupriez V., Adams M.E. J. Biol. Chem. 278:17710-17715(2003) [PubMed: 12586820] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: CantonS EMBL AAO74887.1.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AY220742 mRNA. Translation: AAO74887.1. AE014297 Genomic DNA. Translation: AAS65191.1.
RefSeq	NP_996255.1. NM_206533.1.
UniGene	Dm.16652.
3D structure databases
ProteinModelPortal	Q86C62.
SMR	Q86C62. Positions 7-337.
ModBase	Search...
Protein-protein interaction databases
STRING	Q86C62.
Protein family/group databases
GPCRDB	Search...
Proteomic databases
PRIDE	Q86C62.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblMetazoa	FBtr0084053; FBpp0083455; FBgn0038874.
GeneID	42523.
KEGG	dme:Dmel_CG5911.
NMPDR	fig|7227.3.peg.13882.
UCSC	CG5911-RB. d. melanogaster.
Organism-specific databases
CTD	42523.
FlyBase	FBgn0038874. ETHR.
Phylogenomic databases
eggNOG	inNOG06648.
InParanoid	Q86C62.
OrthoDB	EOG480GC3.
Gene expression databases
ArrayExpress	Q86C62.
Bgee	Q86C62.
Family and domain databases
InterPro	IPR000276. 7TM_GPCR_Rhodpsn. IPR017452. GPCR_Rhodpsn_supfam. [Graphical view]
Pfam	PF00001. 7tm_1. 1 hit. [Graphical view]
PRINTS	PR00237. GPCRRHODOPSN.
PROSITE	PS00237. G_PROTEIN_RECEP_F1_1. 1 hit. PS50262. G_PROTEIN_RECEP_F1_2. 1 hit. [Graphical view]
ProtoNet	Search...
Other
NextBio	829250.

Entry information

Entry name

Q86C62_DROME

Accession

Primary (citable) accession number: Q86C62

Entry history

Integrated into UniProtKB/TrEMBL:	June 1, 2003
Last sequence update:	June 1, 2003
Last modified:	January 25, 2012
This is version 67 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)