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Q86B00 (GLNA1_DICDI) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 61. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Type-1 glutamine synthetase 1

Short name=Type-1 GS 1
EC=6.3.1.2
Alternative name(s):
Type-1 glutamate--ammonia ligase 1
Gene names
Name:glnA1
Synonyms:glnA
ORF Names:DDB_G0276835
OrganismDictyostelium discoideum (Slime mold) [Reference proteome]
Taxonomic identifier44689 [NCBI]
Taxonomic lineageEukaryotaAmoebozoaMycetozoaDictyosteliidaDictyostelium

Protein attributes

Sequence length499 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + L-glutamate + NH3 = ADP + phosphate + L-glutamine.

Sequence similarities

Belongs to the glutamine synthetase family.

Ontologies

Keywords
   LigandATP-binding
Nucleotide-binding
   Molecular functionLigase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processnitrogen compound metabolic process

Inferred from electronic annotation. Source: InterPro

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

glutamate-ammonia ligase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 499499Type-1 glutamine synthetase 1
PRO_0000330467

Sequences

Sequence LengthMass (Da)Tools
Q86B00 [UniParc].

Last modified June 1, 2003. Version 1.
Checksum: 42A903AEE0AA6365

FASTA49956,342
        10         20         30         40         50         60 
MIEPQNNKNI NNNIYNNNNN NFKMNQDENQ LILNSKQLLE KIKISKKKNP QLKFIRVCWI 

        70         80         90        100        110        120 
DISNKIRTKA INIDWILNHE PKLIHVSITN VCMSLLCFED SVTIEALKSE NFGEAFLIPI 

       130        140        150        160        170        180 
TTTKLNILPY CPSHIQIFGE FFYLDNESKK LKPWLLCPRN SLQRAIDRLK NKFGISLKGS 

       190        200        210        220        230        240 
FEEEFYLIKK GDNNNSSVAS LLNSIEKLDH GTFANYHSLD CYGDILEKIT NALEEQGLPI 

       250        260        270        280        290        300 
EQLLSESGSG QFEITIDYTD IMEACDRHII VRQTINSIAS YNGYIATFIP KPFDGLVGSG 

       310        320        330        340        350        360 
CHAHLSLWDT NDSNLTPDAN GECGLSLVNQ FFIGGLLKHS KSLTALFNTT PNSYKRLKPF 

       370        380        390        400        410        420 
YWSGCNVSWG LDNKESFIRI PSSPFSATDG CSNFEIKTID HTSNPYLAMA GIIHAGFDGI 

       430        440        450        460        470        480 
ENSIAPPPPT SLFDQSVLNN QLIPSNFEDA IQSLKENHYL CENIGNDISN AFIHVKLAEN 

       490 
KILKELSDDD QILKLLELF 

« Hide

References

[1]"Sequence and analysis of chromosome 2 of Dictyostelium discoideum."
Gloeckner G., Eichinger L., Szafranski K., Pachebat J.A., Bankier A.T., Dear P.H., Lehmann R., Baumgart C., Parra G., Abril J.F., Guigo R., Kumpf K., Tunggal B., Cox E.C., Quail M.A., Platzer M., Rosenthal A., Noegel A.A.
Nature 418:79-85(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: AX4.
[2]"The genome of the social amoeba Dictyostelium discoideum."
Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R., Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B., Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T., Lehmann R., Hamlin N. expand/collapse author list , Davies R., Gaudet P., Fey P., Pilcher K., Chen G., Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N., Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E., Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N., Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D., Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T., Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D., Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A., Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M., Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A., Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y., Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C., Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R., Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.
Nature 435:43-57(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: AX4.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AAFI02000019 Genomic DNA. Translation: EAL68919.1.

3D structure databases

ProteinModelPortalQ86B00.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING44689.DDB_0231552.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblProtistsDDB0231552; DDB0231552; DDB_G0276835.
KEGGddi:DDB_G0276835.

Organism-specific databases

dictyBaseDDB_G0276835. glnA1.

Phylogenomic databases

eggNOGCOG0174.
OMADNQNLFY.
PhylomeDBQ86B00.
ProtClustDBCLSZ2846857.

Family and domain databases

Gene3D3.30.590.10. 1 hit.
InterProIPR014746. Gln_synth/guanido_kin_cat_dom.
IPR008146. Gln_synth_cat_dom.
[Graphical view]
PfamPF00120. Gln-synt_C. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

PROQ86B00.

Entry information

Entry nameGLNA1_DICDI
AccessionPrimary (citable) accession number: Q86B00
Secondary accession number(s): Q550K6
Entry history
Integrated into UniProtKB/Swiss-Prot: April 29, 2008
Last sequence update: June 1, 2003
Last modified: April 16, 2014
This is version 61 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)

Relevant documents

SIMILARITY comments

Index of protein domains and families

Dictyostelium discoideum

Dictyostelium discoideum: entries, gene names and cross-references to dictyBase