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Protein

Putative glutathione S-transferase alpha-4

Gene

gsta4

Organism
Dictyostelium discoideum (Slime mold)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.By similarity

Catalytic activityi

RX + glutathione = HX + R-S-glutathione.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei48GlutathioneBy similarity1

GO - Molecular functioni

Keywordsi

Molecular functionTransferase

Names & Taxonomyi

Protein namesi
Recommended name:
Putative glutathione S-transferase alpha-4 (EC:2.5.1.18)
Alternative name(s):
GST class-alpha 4
Gene namesi
Name:gsta4
ORF Names:DDB_G0274263
OrganismiDictyostelium discoideum (Slime mold)
Taxonomic identifieri44689 [NCBI]
Taxonomic lineageiEukaryotaAmoebozoaMycetozoaDictyostelidsDictyostelialesDictyosteliaceaeDictyostelium
Proteomesi
  • UP000002195 Componentsi: Chromosome 2, Unassembled WGS sequence

Organism-specific databases

dictyBaseiDDB_G0274263

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003507411 – 225Putative glutathione S-transferase alpha-4Add BLAST225

Proteomic databases

PaxDbiQ86AU1

Interactioni

Protein-protein interaction databases

STRINGi44689.DDB0231430

Structurei

3D structure databases

ProteinModelPortaliQ86AU1
SMRiQ86AU1
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini8 – 85GST N-terminalAdd BLAST78
Domaini87 – 207GST C-terminalAdd BLAST121

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni55 – 56Glutathione bindingBy similarity2
Regioni69 – 70Glutathione bindingBy similarity2

Sequence similaritiesi

Belongs to the GST superfamily. Alpha family.Curated

Phylogenomic databases

eggNOGiKOG1695 Eukaryota
ENOG4111VAU LUCA
InParanoidiQ86AU1
KOiK00799
OMAiPFDDEKC
PhylomeDBiQ86AU1

Family and domain databases

InterProiView protein in InterPro
IPR010987 Glutathione-S-Trfase_C-like
IPR036282 Glutathione-S-Trfase_C_sf
IPR004045 Glutathione_S-Trfase_N
IPR004046 GST_C
IPR036249 Thioredoxin-like_sf
PfamiView protein in Pfam
PF14497 GST_C_3, 1 hit
SUPFAMiSSF47616 SSF47616, 1 hit
SSF52833 SSF52833, 1 hit
PROSITEiView protein in PROSITE
PS50405 GST_CTER, 1 hit
PS50404 GST_NTER, 1 hit

Sequencei

Sequence statusi: Complete.

Q86AU1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MMTTPTNSKP QLTSLRYRGY VQFAQVLMAF HGVDYDMCYV DKIDDQLRKE
60 70 80 90 100
LKFDQLPLFR ETDGFKLNQS LAITKWVGDK YDFIGKSSKE RALVVETVAC
110 120 130 140 150
VHTDIVMPAI RSVLTGQGRD RIINVVIPRY FGAFEKVLTE NKYLACGDSL
160 170 180 190 200
TIADLYCYVA YDYLGHLGFA PDHLQGKFPK IDCLKNHFES NKNVQEYLKK
210 220
RPDDNEFFKN LPDWLKKDSC PTMSC
Length:225
Mass (Da):25,955
Last modified:June 1, 2003 - v1
Checksum:i618933A9DF1CC27A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAFI02000012 Genomic DNA Translation: EAL70024.1
RefSeqiXP_644019.1, XM_638927.1

Genome annotation databases

EnsemblProtistsiEAL70024; EAL70024; DDB_G0274263
GeneIDi8619449
KEGGiddi:DDB_G0274263

Entry informationi

Entry nameiGSTA4_DICDI
AccessioniPrimary (citable) accession number: Q86AU1
Secondary accession number(s): Q555P4
Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 23, 2008
Last sequence update: June 1, 2003
Last modified: March 28, 2018
This is version 91 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health