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Q869X7

- HAT12_DICDI

UniProt

Q869X7 - HAT12_DICDI

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Protein
Histone acetyltransferase type B catalytic subunit DDB_G0275159
Gene
DDB_G0275159
Organism
Dictyostelium discoideum (Slime mold)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

Acetyl-CoA + [histone] = CoA + acetyl-[histone].

GO - Molecular functioni

  1. histone acetyltransferase activity Source: UniProtKB-EC

GO - Biological processi

  1. chromatin silencing at telomere Source: InterPro
  2. histone acetylation Source: dictyBase
Complete GO annotation...

Keywords - Molecular functioni

Acyltransferase, Transferase

Names & Taxonomyi

Protein namesi
Recommended name:
Histone acetyltransferase type B catalytic subunit DDB_G0275159 (EC:2.3.1.48)
Gene namesi
ORF Names:DDB_G0275159
OrganismiDictyostelium discoideum (Slime mold)
Taxonomic identifieri44689 [NCBI]
Taxonomic lineageiEukaryotaAmoebozoaMycetozoaDictyosteliidaDictyostelium
ProteomesiUP000002195: Chromosome 2, UP000002195: Unassembled WGS sequence

Organism-specific databases

dictyBaseiDDB_G0275159.

Subcellular locationi

GO - Cellular componenti

  1. histone acetyltransferase complex Source: dictyBase
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 466466Histone acetyltransferase type B catalytic subunit DDB_G0275159
PRO_0000367832Add
BLAST

Proteomic databases

PRIDEiQ869X7.

Interactioni

Protein-protein interaction databases

STRINGi44689.DDBDRAFT_0167416.

Structurei

3D structure databases

ProteinModelPortaliQ869X7.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini169 – 366198N-acetyltransferase
Add
BLAST

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili372 – 45988 Reviewed prediction
Add
BLAST

Sequence similaritiesi

Belongs to the HAT1 family.

Keywords - Domaini

Coiled coil

Phylogenomic databases

eggNOGiNOG326277.
KOiK11303.
OMAiGPVYDVT.
PhylomeDBiQ869X7.

Family and domain databases

Gene3Di3.40.630.30. 1 hit.
3.90.360.10. 1 hit.
InterProiIPR016181. Acyl_CoA_acyltransferase.
IPR019467. Hat1_N.
IPR017380. Hist_AcTrfase_B-typ_cat-su.
[Graphical view]
PANTHERiPTHR12046. PTHR12046. 1 hit.
PfamiPF10394. Hat1_N. 1 hit.
[Graphical view]
PIRSFiPIRSF038084. HAT-B_cat. 1 hit.
SUPFAMiSSF55729. SSF55729. 1 hit.

Sequencei

Sequence statusi: Complete.

Q869X7-1 [UniParc]FASTAAdd to Basket

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MTSKIKSSNT LLTFDANEVT NIKLVWDIEE LKNKDKEDKA HIKDEEEDED    50
GPVSFHPSFS HQIFNDEQVQ GYEACKIDIY MGAGSLTSYI DTNYTLQSKN 100
LTNVEGELLK VFSKQDPPIS KQSFYKFIEE KEKSFKPIGK KIHEYTITDK 150
ESGEETEYEV YFGRITDQAV FRYHEKLQIF VLWYIDGSSY IWTDDPNWDI 200
FFIFEKRIID GEKRYGITGY STIYNFYHHP EQTRARISQY LILPPYQRMG 250
HGKYLFNSIH QYYKTNDGFY GPVYDVTIED PADDFNLLRN YVDLKNIIDE 300
KLFDNVILDL NANNKSVFEE IRKKLLVPHK QSKVCLEIYL FSKFLATPNS 350
NPKYKEFRIA IKKRLYKQNI GDSEQIEKMK QQVAQENEDN LRLEQEELQE 400
LQDIENKKNG TNIKVAINTK ELTTPSEPEK SKEEIEKDRL EEIIQLYKDL 450
EENYHKTLSS LNLITK 466
Length:466
Mass (Da):55,013
Last modified:June 1, 2003 - v1
Checksum:i16FDB57EB0E4565B
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AAFI02000013 Genomic DNA. Translation: EAL69860.1.
RefSeqiXP_643818.1. XM_638726.1.

Genome annotation databases

EnsemblProtistsiDDB0237833; DDB0237833; DDB_G0275159.
GeneIDi8619865.
KEGGiddi:DDB_G0275159.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AAFI02000013 Genomic DNA. Translation: EAL69860.1 .
RefSeqi XP_643818.1. XM_638726.1.

3D structure databases

ProteinModelPortali Q869X7.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 44689.DDBDRAFT_0167416.

Proteomic databases

PRIDEi Q869X7.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblProtistsi DDB0237833 ; DDB0237833 ; DDB_G0275159 .
GeneIDi 8619865.
KEGGi ddi:DDB_G0275159.

Organism-specific databases

dictyBasei DDB_G0275159.

Phylogenomic databases

eggNOGi NOG326277.
KOi K11303.
OMAi GPVYDVT.
PhylomeDBi Q869X7.

Family and domain databases

Gene3Di 3.40.630.30. 1 hit.
3.90.360.10. 1 hit.
InterProi IPR016181. Acyl_CoA_acyltransferase.
IPR019467. Hat1_N.
IPR017380. Hist_AcTrfase_B-typ_cat-su.
[Graphical view ]
PANTHERi PTHR12046. PTHR12046. 1 hit.
Pfami PF10394. Hat1_N. 1 hit.
[Graphical view ]
PIRSFi PIRSF038084. HAT-B_cat. 1 hit.
SUPFAMi SSF55729. SSF55729. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: AX4.
  2. "The genome of the social amoeba Dictyostelium discoideum."
    Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R., Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B., Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T., Lehmann R., Hamlin N.
    , Davies R., Gaudet P., Fey P., Pilcher K., Chen G., Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N., Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E., Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N., Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D., Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T., Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D., Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A., Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M., Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A., Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y., Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C., Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R., Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.
    Nature 435:43-57(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: AX4.

Entry informationi

Entry nameiHAT12_DICDI
AccessioniPrimary (citable) accession number: Q869X7
Secondary accession number(s): Q553Z3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: June 1, 2003
Last modified: September 3, 2014
This is version 62 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Dictyostelium discoideum
    Dictyostelium discoideum: entries, gene names and cross-references to dictyBase
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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