Unreviewed, UniProtKB/TrEMBL Q868M7 (Q868M7_CUCEC)

Names and origin

Protein names

Submitted name:
    Hemolytic lectin CEL-III EMBL BAC75827.1

Gene names

Name:

cel3 EMBL BAC75827.1

Organism

Cucumaria echinata (Sea cucumber) EMBL BAC75827.1

Taxonomic identifier

40245 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Echinodermata › Eleutherozoa › Echinozoa › Holothuroidea › Dendrochirotacea › Dendrochirotida › Cucumariidae › Cucumaria

Protein attributes

Sequence length	442 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at protein level.

Ontologies

Keywords
Ligand	Lectin
Gene Ontology (GO)
Molecular function	sugar binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q868M7-1 [UniParc]. Last modified June 1, 2003. Version 1. Checksum: 3E47C608446D40EC	FASTA	442	48,456
	10 20 30 40 50 60 MVSLVPCGFA QVLCTNPLDI GELRNYKSKQ CVDIVGNQGS GNIATHDCDG LSDQQIIMCG 70 80 90 100 110 120 DGTIRNEARN YCFTPDGSGN ANVMSSPCTL YPEIPSSQRW RLGRKKAFTD NGGIEQVATE 130 140 150 160 170 180 IINLASGKCL DVEGSDGTGD IGVYDCQNLD DQYFYIRSRG PELFYGRLRN EKSDLCLDVE 190 200 210 220 230 240 GSEGKGNVLM YSCEDNLDQW FRYYENGEIV NAKQGMCLDV EGSDGSGNVG IYRCDDLRDQ 250 260 270 280 290 300 MWSRPNAYCN GDYCSFLNKE SNKCLDVSGD QGTGDVGTWQ CDGLPDQRFK WVFDDWEVPT 310 320 330 340 350 360 ATWNMVGCDQ NGKVSQQISN TISFSSTVTA GVAVEVSSTI EKGVIFAKAS VSVKVTASLS 370 380 390 400 410 420 KAWTNSQSGT TAITYTCDNY DSDEEFTRGC MWQLAIETTE VKSGDLLVWN PQIIKCTRSN 430 440 TAPGCAPFTK CANEDCTFCT DI

References

[1]	"Primary structure of hemolytic lectin CEL-III from marine invertebrate Cucumaria echinata and its cDNA: structural similarity to the B-chain from plant lectin, ricin." Nakano M., Tabata S., Sugihara K., Kouzuma Y., Kimura M., Yamasaki N. Biochim. Biophys. Acta 1435:167-176(1999) [PubMed: 10561549] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.
[2]	Kouzuma Y. Submitted (APR-2003) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
[3]	"Crystal structure of the hemolytic lectin CEL-III isolated from the marine invertebrate Cucumaria echinata: implications of domain structure for its membrane pore-formation mechanism." Uchida T., Yamasaki T., Eto S., Sugawara H., Kurisu G., Nakagawa A., Kusunoki M., Hatakeyama T. J. Biol. Chem. 279:37133-37141(2004) [PubMed: 15194688] [Abstract] Cited for: X-RAY CRYSTALLOGRAPHY (1.7 ANGSTROMS) OF 11-442.
+	Additional computationally mapped references.

Cross-references

Sequence databases

EMBLGenBankDDBJ

AB109017 mRNA. Translation: BAC75827.1.

3D structure databases

PDBPDBe

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
1VCL	X-ray	1.70	A/B	12-442	[»]
2Z48	X-ray	1.70	A/B	12-442	[»]
2Z49	X-ray	1.95	A/B	12-442	[»]

ModBase

Search...

Protein family/group databases

CAZy

CBM13. Carbohydrate-Binding Module Family 13.

Family and domain databases

InterPro

IPR000772. Ricin_B_lectin.
[Graphical view]

Pfam

PF00652. Ricin_B_lectin. 3 hits.
[Graphical view]

SMART

SM00458. RICIN. 2 hits.
[Graphical view]

PROSITE

PS50231. RICIN_B_LECTIN. 3 hits.
[Graphical view]

ProtoNet

Search...

Entry information

Entry name

Q868M7_CUCEC

Accession

Primary (citable) accession number: Q868M7

Entry history

Integrated into UniProtKB/TrEMBL:	June 1, 2003
Last sequence update:	June 1, 2003
Last modified:	June 16, 2009
This is version 23 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)