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Protein

Latherin

Gene

LATH

Organism
Equus burchellii antiquorum (Damara zebra) (Chapman zebra)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Major protein in sweat, has surfactant properties.By similarity

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
Latherin
Gene namesi
Name:LATH
OrganismiEquus burchellii antiquorum (Damara zebra) (Chapman zebra)
Taxonomic identifieri200155 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaPerissodactylaEquidaeEquus

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_0000089161‹1 – ›205LatherinAdd BLAST›205

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi133 ↔ 176By similarity

Keywords - PTMi

Disulfide bond

Interactioni

Subunit structurei

Monomer.By similarity

Family & Domainsi

Sequence similaritiesi

Belongs to the BPI/LBP/Plunc superfamily. Plunc family.Curated

Phylogenomic databases

HOVERGENiHBG079669.

Family and domain databases

InterProiIPR017943. Bactericidal_perm-incr_a/b_dom.
IPR032942. BPI/LBP/Plunc.
IPR032953. BPIFA1/Latherin.
IPR017942. Lipid-bd_serum_glycop_N.
[Graphical view]
PANTHERiPTHR10504. PTHR10504. 1 hit.
PTHR10504:SF70. PTHR10504:SF70. 1 hit.
PfamiPF01273. LBP_BPI_CETP. 1 hit.
[Graphical view]
SUPFAMiSSF55394. SSF55394. 1 hit.

Sequencei

Sequence statusi: Fragment.

Q865V1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
QQIPPEVSSQ ITDALTQGLL DGNFLSLLNA INLEGLLNTI LDQVTGLLNI
60 70 80 90 100
LVGPLLGSSN AEIKLQDARL LQLSLEFSPD SKGIDIWIPL ELSVYLKLLI
110 120 130 140 150
LEPLTLYVRT DIRAQLQLES DEDGKYRLAF GHCTLLPRAI ELQTGNPLSL
160 170 180 190 200
TVNAVLGTIE NTLGNFITED LGAGLCPTLN SLVSNLNLQL VNNLINLILD

RANVD
Length:205
Mass (Da):22,290
Last modified:June 1, 2003 - v1
Checksum:i637856CEF8B44D1D
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei11
Non-terminal residuei2051

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY226145 mRNA. Translation: AAO73936.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY226145 mRNA. Translation: AAO73936.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

HOVERGENiHBG079669.

Family and domain databases

InterProiIPR017943. Bactericidal_perm-incr_a/b_dom.
IPR032942. BPI/LBP/Plunc.
IPR032953. BPIFA1/Latherin.
IPR017942. Lipid-bd_serum_glycop_N.
[Graphical view]
PANTHERiPTHR10504. PTHR10504. 1 hit.
PTHR10504:SF70. PTHR10504:SF70. 1 hit.
PfamiPF01273. LBP_BPI_CETP. 1 hit.
[Graphical view]
SUPFAMiSSF55394. SSF55394. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiLATH_EQUBA
AccessioniPrimary (citable) accession number: Q865V1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 7, 2003
Last sequence update: June 1, 2003
Last modified: May 11, 2016
This is version 33 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.