Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q864U6

- B3GL1_PIG

UniProt

Q864U6 - B3GL1_PIG

Protein

UDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase 1

Gene

B3GALNT1

Organism
Sus scrofa (Pig)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 63 (01 Oct 2014)
      Sequence version 1 (01 Jun 2003)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Transfers N-acetylgalactosamine onto globotriaosylceramide.By similarity

    Catalytic activityi

    UDP-N-acetyl-alpha-D-galactosamine + alpha-D-galactosyl-(1->4)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide = UDP + N-acetyl-beta-D-galactosaminyl-(1->3)-alpha-D-galactosyl-(1->4)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide.

    Cofactori

    Magnesium.By similarity

    Pathwayi

    GO - Molecular functioni

    1. galactosylgalactosylglucosylceramide beta-D-acetylgalactosaminyltransferase activity Source: UniProtKB-EC
    2. UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity Source: Ensembl

    GO - Biological processi

    1. oligosaccharide biosynthetic process Source: Ensembl
    2. protein glycosylation Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    Glycosyltransferase, Transferase

    Keywords - Ligandi

    Magnesium

    Enzyme and pathway databases

    UniPathwayiUPA00378.

    Protein family/group databases

    CAZyiGT31. Glycosyltransferase Family 31.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    UDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase 1 (EC:2.4.1.79)
    Short name:
    Beta-1,3-GalNAc-T1
    Alternative name(s):
    Beta-1,3-galactosyltransferase 3
    Short name:
    Beta-1,3-GalTase 3
    Short name:
    Beta3Gal-T3
    Short name:
    Beta3GalT3
    Short name:
    b3Gal-T3
    Beta-3-Gx-T3
    Galactosylgalactosylglucosylceramide beta-D-acetyl-galactosaminyltransferase
    Globoside synthase
    UDP-N-acetylgalactosamine:globotriaosylceramide beta-1,3-N-acetylgalactosaminyltransferase
    Gene namesi
    Name:B3GALNT1
    Synonyms:B3GALT3
    OrganismiSus scrofa (Pig)
    Taxonomic identifieri9823 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaSuinaSuidaeSus
    ProteomesiUP000008227: Chromosome 13

    Subcellular locationi

    GO - Cellular componenti

    1. Golgi membrane Source: UniProtKB-SubCell
    2. integral component of membrane Source: UniProtKB-KW

    Keywords - Cellular componenti

    Golgi apparatus, Membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 331331UDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase 1PRO_0000219156Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Glycosylationi72 – 721N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi154 – 1541N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi198 – 1981N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi212 – 2121N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi326 – 3261N-linked (GlcNAc...)Sequence Analysis

    Keywords - PTMi

    Glycoprotein

    Structurei

    3D structure databases

    ProteinModelPortaliQ864U6.
    ModBaseiSearch...
    MobiDBiSearch...

    Topological domain

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Topological domaini1 – 2020CytoplasmicSequence AnalysisAdd
    BLAST
    Topological domaini44 – 331288LumenalSequence AnalysisAdd
    BLAST

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei21 – 4323Helical; Signal-anchor for type II membrane proteinSequence AnalysisAdd
    BLAST

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the glycosyltransferase 31 family.Curated

    Keywords - Domaini

    Signal-anchor, Transmembrane, Transmembrane helix

    Phylogenomic databases

    GeneTreeiENSGT00740000114871.
    HOVERGENiHBG101817.
    KOiK00719.
    OMAiCPNAKYI.
    OrthoDBiEOG7M3J0F.
    TreeFamiTF318639.

    Family and domain databases

    InterProiIPR002659. Glyco_trans_31.
    [Graphical view]
    PANTHERiPTHR11214. PTHR11214. 1 hit.
    PfamiPF01762. Galactosyl_T. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q864U6-1 [UniParc]FASTAAdd to Basket

    « Hide

    MAPALPITLP SKMSLRSLKW SLLLLSLLSF LVMWYLSLPH YNVIERVNWM    50
    YFYEYEPIYR QDFHFTLREH SNCSHQNPFL VILVTSHPAD VKARQAIRVT 100
    WGEKKSWWGY EVLTFFLLGQ QAEREDKVLA LSLEDEHLLY GDIIRQDFLD 150
    TYNNLTLKTI MAFRWVTEFC PNARYIMKTD TDVFINTGNL VKYLLNLNHS 200
    EKFFTGYPLI DNYSYRGFYQ KTHISYQEYP FKVFPPYCSG LGYIMSRDLV 250
    PRIYEMMSHV KPIKFEDVYV GICLNLLKVD IHIPEDTNLF FLYRIHLDVC 300
    QLRRVIAAHG FSSKEIITFW QVMLRNTTCH Y 331
    Length:331
    Mass (Da):39,437
    Last modified:June 1, 2003 - v1
    Checksum:i3686FB95DA581CE3
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AY253340 mRNA. Translation: AAO92025.1.
    RefSeqiNP_999516.1. NM_214351.1.
    XP_005652470.1. XM_005652413.1.
    UniGeneiSsc.13482.

    Genome annotation databases

    EnsembliENSSSCT00000026210; ENSSSCP00000023800; ENSSSCG00000021774.
    GeneIDi397634.
    KEGGissc:397634.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AY253340 mRNA. Translation: AAO92025.1 .
    RefSeqi NP_999516.1. NM_214351.1.
    XP_005652470.1. XM_005652413.1.
    UniGenei Ssc.13482.

    3D structure databases

    ProteinModelPortali Q864U6.
    ModBasei Search...
    MobiDBi Search...

    Protein family/group databases

    CAZyi GT31. Glycosyltransferase Family 31.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSSSCT00000026210 ; ENSSSCP00000023800 ; ENSSSCG00000021774 .
    GeneIDi 397634.
    KEGGi ssc:397634.

    Organism-specific databases

    CTDi 8706.

    Phylogenomic databases

    GeneTreei ENSGT00740000114871.
    HOVERGENi HBG101817.
    KOi K00719.
    OMAi CPNAKYI.
    OrthoDBi EOG7M3J0F.
    TreeFami TF318639.

    Enzyme and pathway databases

    UniPathwayi UPA00378 .

    Family and domain databases

    InterProi IPR002659. Glyco_trans_31.
    [Graphical view ]
    PANTHERi PTHR11214. PTHR11214. 1 hit.
    Pfami PF01762. Galactosyl_T. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Python P., Joerg H., Neuenschwander S., Stranzinger G., Voegeli P.
      Submitted (MAR-2003) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [MRNA].
      Tissue: Small intestine.

    Entry informationi

    Entry nameiB3GL1_PIG
    AccessioniPrimary (citable) accession number: Q864U6
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: July 5, 2005
    Last sequence update: June 1, 2003
    Last modified: October 1, 2014
    This is version 63 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3