Q85UU0 (NDHH_ANTFO) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
NAD(P)H-quinone oxidoreductase subunit H, chloroplastic
EC=1.6.5.-

Alternative name(s):
NAD(P)H dehydrogenase subunit H
NADH-plastoquinone oxidoreductase 49 kDa subunit
NADH-plastoquinone oxidoreductase subunit H

Gene names

Name:

ndhH

Encoded on

Plastid; Chloroplast

Organism

Anthoceros formosae (Hornwort)

Taxonomic identifier

48387 [NCBI]

Taxonomic lineage

Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Anthocerotophyta › Anthocerotopsida › Anthocerotidae › Anthocerotales › Anthocerotaceae › Anthoceros

Protein attributes

Sequence length	393 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Function	NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient By similarity. HAMAP MF_01358
Catalytic activity	NAD(P)H + plastoquinone = NAD(P)+ + plastoquinol. HAMAP MF_01358
Subunit structure	NDH is composed of at least 16 different subunits, 5 of which are encoded in the nucleus By similarity.
Subcellular location	Plastid › chloroplast thylakoid membrane; Peripheral membrane protein; Stromal side By similarity HAMAP MF_01358.
Sequence similarities	Belongs to the complex I 49 kDa subunit family.
RNA editing	Edited at positions 32, 42, 75, 110, 128, 130, 147, 157, 169, 170, 182, 202, 209, 215, 230, 234, 260, 290, 293, 341, 349 and 393. The nonsense codons at positions 128, 202, 230 and 293 are modified to sense codons. Ref.1 Ref.2

Ontologies

Keywords
Biological process	Transport
Cellular component	Chloroplast Membrane Plastid Thylakoid
Coding sequence diversity	RNA editing
Ligand	NAD NADP Plastoquinone
Molecular function	Oxidoreductase
PTM	Quinone
Gene Ontology (GO)
Biological process	transport Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	chloroplast thylakoid membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	NAD binding Inferred from electronic annotation. Source: InterPro oxidoreductase activity, acting on NADH or NADPH Inferred from electronic annotation. Source: InterPro quinone binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 393	393	NAD(P)H-quinone oxidoreductase subunit H, chloroplastic HAMAP MF_01358		PRO_0000118597

Sequences

	Sequence		Length	Mass (Da)
	Q85UU0 [UniParc]. Last modified June 1, 2003. Version 1. Checksum: 9858E72DD68C3941	FASTA	393	45,334
	10 20 30 40 50 60 MTMLAAKADP MTLSMGPHHP SMHGVLRLIV TLDGENVTDC EPILGYLHRG MEKIAENRTI 70 80 90 100 110 120 VQYLPYVTRW DYLATMFTEA ITVNAPEKLT NIQVPKRASY IRIIMLELSR IASHLLWLGP 130 140 150 160 170 180 FMADIGAQTP FFYILREREM IYDLFEAATG MRMMHNFFRI GGVAVDLPYG WVDKCLDFCD 190 200 210 220 230 240 YFSLKVDEYE RLITYNSIFL KRVEGVGTIS REEAINWGLS GLMLRASGVQ WDLRKVDHYE 250 260 270 280 290 300 CYDELDWQVQ SQTEGDSLAR YLVRIGEMRE SVKIIQQALK VIPGGPYENL EARRLNQGKD 310 320 330 340 350 360 SEWNDFEYQF ISKKPSPTFK LPKQEHYIRV EAPKGELGIY LIGDDSVFPW RWKIRPPGFI 370 380 390 NLQILPQLVK GMKLADIMTI LGSIDIIMGE VDR

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The complete nucleotide sequence of the hornwort (Anthoceros formosae) chloroplast genome: insight into the earliest land plants." Kugita M., Kaneko A., Yamamoto Y., Takeya Y., Matsumoto T., Yoshinaga K. Nucleic Acids Res. 31:716-721(2003) [PubMed: 12527781] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], RNA EDITING. Tissue: Thallus.
[2]	"RNA editing in hornwort chloroplasts makes more than half the genes functional." Kugita M., Yamamoto Y., Fujikawa T., Matsumoto T., Yoshinaga K. Nucleic Acids Res. 31:2417-2423(2003) [PubMed: 12711687] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA], RNA EDITING. Tissue: Thallus.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AB087490 mRNA. Translation: BAC55507.1. AB086179 Genomic DNA. Translation: BAC55407.2. Sequence problems.
RefSeq	NP_777470.1. NC_004543.1.
3D structure databases
ProteinModelPortal	Q85UU0.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	2553501.
Phylogenomic databases
ProtClustDB	CHL00017.
Family and domain databases
HAMAP	MF_01358. NDH1_NuoD. [Tree]
InterPro	IPR010219. NADH_DH_1_suD. IPR001135. NADH_Q_OxRdtase_suD. IPR014029. NADH_UbQ_OxRdtase_49kDa_CS. IPR022885. NDH1_su_D/H. [Graphical view]
Pfam	PF00346. Complex1_49kDa. 1 hit. [Graphical view]
TIGRFAMs	TIGR01962. NuoD. 1 hit.
PROSITE	PS00535. COMPLEX1_49K. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

NDHH_ANTFO

Accession

Primary (citable) accession number: Q85UU0
Secondary accession number(s): Q85WB4

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 29, 2004
Last sequence update:	June 1, 2003
Last modified:	September 21, 2011
This is version 49 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Plant Protein Annotation Program