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Q85Q96

- COX3_CANGA

UniProt

Q85Q96 - COX3_CANGA

Protein

Cytochrome c oxidase subunit 3

Gene

COX3

Organism
Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65) (Yeast) (Torulopsis glabrata)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 68 (01 Oct 2014)
      Sequence version 1 (01 Jun 2003)
      Previous versions | rss
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    Functioni

    Subunits I, II and III form the functional core of the enzyme complex.

    Catalytic activityi

    4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O.

    GO - Molecular functioni

    1. cytochrome-c oxidase activity Source: UniProtKB-EC

    GO - Biological processi

    1. aerobic electron transport chain Source: InterPro
    2. hydrogen ion transmembrane transport Source: GOC
    3. mitochondrial electron transport, cytochrome c to oxygen Source: CGD

    Keywords - Molecular functioni

    Oxidoreductase

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Cytochrome c oxidase subunit 3 (EC:1.9.3.1)
    Alternative name(s):
    Cytochrome c oxidase polypeptide III
    Cytochrome oxidase subunit 3
    Gene namesi
    Name:COX3
    Encoded oniMitochondrion
    OrganismiCandida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65) (Yeast) (Torulopsis glabrata)
    Taxonomic identifieri284593 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeNakaseomycesmitosporic Nakaseomyces
    ProteomesiUP000002428: Mitochondrion

    Subcellular locationi

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB-KW
    2. mitochondrial respiratory chain complex IV Source: CGD

    Keywords - Cellular componenti

    Membrane, Mitochondrion, Mitochondrion inner membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 269269Cytochrome c oxidase subunit 3PRO_0000183752Add
    BLAST

    Structurei

    3D structure databases

    ProteinModelPortaliQ85Q96.
    ModBaseiSearch...
    MobiDBiSearch...

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei21 – 4121HelicalSequence AnalysisAdd
    BLAST
    Transmembranei45 – 6521HelicalSequence AnalysisAdd
    BLAST
    Transmembranei90 – 11021HelicalSequence AnalysisAdd
    BLAST
    Transmembranei138 – 16023HelicalSequence AnalysisAdd
    BLAST
    Transmembranei167 – 18721HelicalSequence AnalysisAdd
    BLAST
    Transmembranei205 – 22521HelicalSequence AnalysisAdd
    BLAST
    Transmembranei247 – 26721HelicalSequence AnalysisAdd
    BLAST

    Family & Domainsi

    Sequence similaritiesi

    Keywords - Domaini

    Transmembrane, Transmembrane helix

    Phylogenomic databases

    HOGENOMiHOG000264954.
    KOiK02262.
    OrthoDBiEOG7V76HP.

    Family and domain databases

    Gene3Di1.20.120.80. 1 hit.
    InterProiIPR024791. Cyt_c/ubiquinol_Oxase_su3.
    IPR013833. Cyt_c_oxidase_su3_a-hlx.
    IPR000298. Cyt_c_oxidase_su3_dom.
    [Graphical view]
    PANTHERiPTHR11403. PTHR11403. 1 hit.
    PfamiPF00510. COX3. 1 hit.
    [Graphical view]
    SUPFAMiSSF81452. SSF81452. 1 hit.
    PROSITEiPS50253. COX3. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q85Q96-1 [UniParc]FASTAAdd to Basket

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    MTHLERSRHQ QYPYHMVLPS PWPMLLSFAL LSLTLSLGLT MHGYIGNMNL    50
    VYLALLVVTL TSVFWFRDVI AEATYLGDHT IAVRKGINLG FLLFVLSEVL 100
    IFAGLFWAYF HSAMSPDIVL GASWPPVGIQ AVQPTELPLL NTIILLSSGA 150
    TITYSHHALI CRNRNKALSG LFITIWLIII FVTCQYIEYT NAAFTISDGV 200
    YGSVFYAGTG LHFLHMVMLA VMLIICYWRM RTYQFTSTHH VGFETTILYC 250
    HVLDIIWLFL YIVFYWWGV 269
    Length:269
    Mass (Da):30,717
    Last modified:June 1, 2003 - v1
    Checksum:iB9890E82E064080E
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AJ511533 Genomic DNA. Translation: CAD54427.1.
    RefSeqiNP_818786.1. NC_004691.1.

    Genome annotation databases

    GeneIDi807011.
    KEGGicgr:CaglfMp12.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AJ511533 Genomic DNA. Translation: CAD54427.1 .
    RefSeqi NP_818786.1. NC_004691.1.

    3D structure databases

    ProteinModelPortali Q85Q96.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 807011.
    KEGGi cgr:CaglfMp12.

    Phylogenomic databases

    HOGENOMi HOG000264954.
    KOi K02262.
    OrthoDBi EOG7V76HP.

    Family and domain databases

    Gene3Di 1.20.120.80. 1 hit.
    InterProi IPR024791. Cyt_c/ubiquinol_Oxase_su3.
    IPR013833. Cyt_c_oxidase_su3_a-hlx.
    IPR000298. Cyt_c_oxidase_su3_dom.
    [Graphical view ]
    PANTHERi PTHR11403. PTHR11403. 1 hit.
    Pfami PF00510. COX3. 1 hit.
    [Graphical view ]
    SUPFAMi SSF81452. SSF81452. 1 hit.
    PROSITEi PS50253. COX3. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The complete mitochondrial genome sequence of the pathogenic yeast Candida (Torulopsis) glabrata."
      Koszul R., Malpertuy A., Frangeul L., Bouchier C., Wincker P., Thierry A., Duthoy S., Ferris S., Hennequin C., Dujon B.
      FEBS Lett. 534:39-48(2003) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65.

    Entry informationi

    Entry nameiCOX3_CANGA
    AccessioniPrimary (citable) accession number: Q85Q96
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: August 16, 2004
    Last sequence update: June 1, 2003
    Last modified: October 1, 2014
    This is version 68 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programFungal Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3