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Q85FX1

- ODPB_CYAME

UniProt

Q85FX1 - ODPB_CYAME

Protein

Pyruvate dehydrogenase E1 component subunit beta

Gene

pdhB

Organism
Cyanidioschyzon merolae (Red alga)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 59 (01 Oct 2014)
      Sequence version 1 (01 Jun 2003)
      Previous versions | rss
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    Functioni

    The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3) By similarity.By similarity

    Catalytic activityi

    Pyruvate + [dihydrolipoyllysine-residue acetyltransferase] lipoyllysine = [dihydrolipoyllysine-residue acetyltransferase] S-acetyldihydrolipoyllysine + CO2.

    Cofactori

    Thiamine pyrophosphate.By similarity

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei61 – 611Thiamine pyrophosphateBy similarity

    GO - Molecular functioni

    1. pyruvate dehydrogenase (acetyl-transferring) activity Source: UniProtKB-EC
    2. zinc ion binding Source: EnsemblPlants/Gramene

    GO - Biological processi

    1. glycolytic process Source: UniProtKB-KW
    2. pollen tube development Source: EnsemblPlants/Gramene

    Keywords - Molecular functioni

    Oxidoreductase

    Keywords - Biological processi

    Glycolysis

    Keywords - Ligandi

    Pyruvate, Thiamine pyrophosphate

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Pyruvate dehydrogenase E1 component subunit beta (EC:1.2.4.1)
    Gene namesi
    Name:pdhB
    Synonyms:odpB
    Encoded oniPlastid; Chloroplast
    OrganismiCyanidioschyzon merolae (Red alga)
    Taxonomic identifieri45157 [NCBI]
    Taxonomic lineageiEukaryotaRhodophytaBangiophyceaeCyanidialesCyanidiaceaeCyanidioschyzon

    Subcellular locationi

    GO - Cellular componenti

    1. chloroplast envelope Source: EnsemblPlants/Gramene
    2. chloroplast stroma Source: EnsemblPlants/Gramene

    Keywords - Cellular componenti

    Chloroplast, Plastid

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 326326Pyruvate dehydrogenase E1 component subunit betaPRO_0000280106Add
    BLAST

    Interactioni

    Subunit structurei

    Heterodimer of an alpha and a beta chain.By similarity

    Structurei

    3D structure databases

    ProteinModelPortaliQ85FX1.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Phylogenomic databases

    PhylomeDBiQ85FX1.

    Family and domain databases

    Gene3Di3.40.50.920. 1 hit.
    3.40.50.970. 1 hit.
    InterProiIPR029061. THDP-binding.
    IPR009014. Transketo_C/Pyr-ferredox_oxred.
    IPR005475. Transketolase-like_Pyr-bd.
    IPR005476. Transketolase_C.
    [Graphical view]
    PfamiPF02779. Transket_pyr. 1 hit.
    PF02780. Transketolase_C. 1 hit.
    [Graphical view]
    SMARTiSM00861. Transket_pyr. 1 hit.
    [Graphical view]
    SUPFAMiSSF52518. SSF52518. 1 hit.
    SSF52922. SSF52922. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q85FX1-1 [UniParc]FASTAAdd to Basket

    « Hide

    MLHKLFMYEA LREAIDEEMA RDKRVFVLGE DVGHYGGSYK VTKQLHTKYG    50
    DLRVLDTPIA ENSFTGMAIG AAMTGLKPVV EGMNLSFLLL AFNQISNNAG 100
    MLHYTSGGNW SIPLVIRGPG GIGKQLSAEH SQRIEAYFQA VPGLKIVACS 150
    TPYNAKGLLK AAIRDNNPVL FLEHVLLYNL KQEIPKQEYV LPLDKAQVVR 200
    EGSDVTIITY SRMLHHVMQA VKQLVAQGMN PEVIDLISLK PIDLETLVTS 250
    VSKTHKAIIV EECMQTGGIA AEVMAQIYSH AFDELDAPIR RLSSKDVPTP 300
    YNGYLEQACL VQPTQIVEAV KTLMST 326
    Length:326
    Mass (Da):35,983
    Last modified:June 1, 2003 - v1
    Checksum:iFA96561EDDF71DF3
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AB002583 Genomic DNA. Translation: BAC76222.1.
    RefSeqiNP_849060.1. NC_004799.1.

    Genome annotation databases

    GeneIDi844910.
    KEGGicme:CymeCp128.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AB002583 Genomic DNA. Translation: BAC76222.1 .
    RefSeqi NP_849060.1. NC_004799.1.

    3D structure databases

    ProteinModelPortali Q85FX1.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 844910.
    KEGGi cme:CymeCp128.

    Phylogenomic databases

    PhylomeDBi Q85FX1.

    Family and domain databases

    Gene3Di 3.40.50.920. 1 hit.
    3.40.50.970. 1 hit.
    InterProi IPR029061. THDP-binding.
    IPR009014. Transketo_C/Pyr-ferredox_oxred.
    IPR005475. Transketolase-like_Pyr-bd.
    IPR005476. Transketolase_C.
    [Graphical view ]
    Pfami PF02779. Transket_pyr. 1 hit.
    PF02780. Transketolase_C. 1 hit.
    [Graphical view ]
    SMARTi SM00861. Transket_pyr. 1 hit.
    [Graphical view ]
    SUPFAMi SSF52518. SSF52518. 1 hit.
    SSF52922. SSF52922. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Complete sequence and analysis of the plastid genome of the unicellular red alga Cyanidioschyzon merolae."
      Ohta N., Matsuzaki M., Misumi O., Miyagishima S.-Y., Nozaki H., Tanaka K., Shin-i T., Kohara Y., Kuroiwa T.
      DNA Res. 10:67-77(2003) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: 10D.

    Entry informationi

    Entry nameiODPB_CYAME
    AccessioniPrimary (citable) accession number: Q85FX1
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: March 6, 2007
    Last sequence update: June 1, 2003
    Last modified: October 1, 2014
    This is version 59 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)