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Q85FX1 (ODPB_CYAME) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 58. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
Pyruvate dehydrogenase E1 component subunit beta

EC=1.2.4.1
Gene names
Name:pdhB
Synonyms:odpB
Encoded onPlastid; Chloroplast
OrganismCyanidioschyzon merolae (Red alga)
Taxonomic identifier45157 [NCBI]
Taxonomic lineageEukaryotaRhodophytaBangiophyceaeCyanidialesCyanidiaceaeCyanidioschyzon

Protein attributes

Sequence length326 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3) By similarity.

Catalytic activity

Pyruvate + [dihydrolipoyllysine-residue acetyltransferase] lipoyllysine = [dihydrolipoyllysine-residue acetyltransferase] S-acetyldihydrolipoyllysine + CO2.

Cofactor

Thiamine pyrophosphate By similarity.

Subunit structure

Heterodimer of an alpha and a beta chain By similarity.

Subcellular location

Plastidchloroplast.

Ontologies

Keywords
   Biological processGlycolysis
   Cellular componentChloroplast
Plastid
   LigandPyruvate
Thiamine pyrophosphate
   Molecular functionOxidoreductase
Gene Ontology (GO)
   Biological_processglycolytic process

Inferred from electronic annotation. Source: UniProtKB-KW

pollen tube development

Inferred from electronic annotation. Source: EnsemblPlants/Gramene

   Cellular_componentchloroplast envelope

Inferred from electronic annotation. Source: EnsemblPlants/Gramene

chloroplast stroma

Inferred from electronic annotation. Source: EnsemblPlants/Gramene

   Molecular_functionpyruvate dehydrogenase (acetyl-transferring) activity

Inferred from electronic annotation. Source: UniProtKB-EC

zinc ion binding

Inferred from electronic annotation. Source: EnsemblPlants/Gramene

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 326326Pyruvate dehydrogenase E1 component subunit beta
PRO_0000280106

Sites

Binding site611Thiamine pyrophosphate By similarity

Sequences

Sequence LengthMass (Da)Tools
Q85FX1 [UniParc].

Last modified June 1, 2003. Version 1.
Checksum: FA96561EDDF71DF3

FASTA32635,983
        10         20         30         40         50         60 
MLHKLFMYEA LREAIDEEMA RDKRVFVLGE DVGHYGGSYK VTKQLHTKYG DLRVLDTPIA 

        70         80         90        100        110        120 
ENSFTGMAIG AAMTGLKPVV EGMNLSFLLL AFNQISNNAG MLHYTSGGNW SIPLVIRGPG 

       130        140        150        160        170        180 
GIGKQLSAEH SQRIEAYFQA VPGLKIVACS TPYNAKGLLK AAIRDNNPVL FLEHVLLYNL 

       190        200        210        220        230        240 
KQEIPKQEYV LPLDKAQVVR EGSDVTIITY SRMLHHVMQA VKQLVAQGMN PEVIDLISLK 

       250        260        270        280        290        300 
PIDLETLVTS VSKTHKAIIV EECMQTGGIA AEVMAQIYSH AFDELDAPIR RLSSKDVPTP 

       310        320 
YNGYLEQACL VQPTQIVEAV KTLMST 

« Hide

References

[1]"Complete sequence and analysis of the plastid genome of the unicellular red alga Cyanidioschyzon merolae."
Ohta N., Matsuzaki M., Misumi O., Miyagishima S.-Y., Nozaki H., Tanaka K., Shin-i T., Kohara Y., Kuroiwa T.
DNA Res. 10:67-77(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 10D.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AB002583 Genomic DNA. Translation: BAC76222.1.
RefSeqNP_849060.1. NC_004799.1.

3D structure databases

ProteinModelPortalQ85FX1.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID844910.
KEGGcme:CymeCp128.

Phylogenomic databases

PhylomeDBQ85FX1.

Family and domain databases

Gene3D3.40.50.920. 1 hit.
3.40.50.970. 1 hit.
InterProIPR029061. THDP-binding.
IPR009014. Transketo_C/Pyr-ferredox_oxred.
IPR005475. Transketolase-like_Pyr-bd.
IPR005476. Transketolase_C.
[Graphical view]
PfamPF02779. Transket_pyr. 1 hit.
PF02780. Transketolase_C. 1 hit.
[Graphical view]
SMARTSM00861. Transket_pyr. 1 hit.
[Graphical view]
SUPFAMSSF52518. SSF52518. 1 hit.
SSF52922. SSF52922. 1 hit.
ProtoNetSearch...

Entry information

Entry nameODPB_CYAME
AccessionPrimary (citable) accession number: Q85FX1
Entry history
Integrated into UniProtKB/Swiss-Prot: March 6, 2007
Last sequence update: June 1, 2003
Last modified: June 11, 2014
This is version 58 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)