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Q857H2 (VG50_BPMB2) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 58. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Putative adenosylcobalamin-dependent ribonucleoside-triphosphate reductase

EC=1.17.4.2
Alternative name(s):
Gp50
Gene names
Name:50
OrganismMycobacterium phage Bxz2 (Mycobacteriophage Bxz2) [Complete proteome]
Taxonomic identifier205870 [NCBI]
Taxonomic lineageVirusesdsDNA viruses, no RNA stageCaudoviralesSiphoviridae
Virus hostMycobacterium [TaxID: 1763]

Protein attributes

Sequence length672 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

2'-deoxyribonucleoside triphosphate + thioredoxin disulfide + H2O = ribonucleoside triphosphate + thioredoxin.

Cofactor

Adenosylcobalamin By similarity.

Sequence similarities

Belongs to the class II ribonucleoside-triphosphate reductase family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 672672Putative adenosylcobalamin-dependent ribonucleoside-triphosphate reductase
PRO_0000221429

Sites

Active site3561 By similarity
Active site3581 By similarity

Amino acid modifications

Disulfide bond86 ↔ 367Redox-active By similarity

Sequences

Sequence LengthMass (Da)Tools
Q857H2 [UniParc].

Last modified June 1, 2003. Version 1.
Checksum: F1C8F1FFBEA25E12

FASTA67275,158
        10         20         30         40         50         60 
MTNWGPTGEL VYNRTYSRTK PDGSKETWPE TVRRVVDGNL ALVDERYHLP GERADLIRLM 

        70         80         90        100        110        120 
EEFKILPGGR HLWASGVKNA QHLFNCWVSG WTEKPSDHFE FTFMRLMEGG GVGANYSNRF 

       130        140        150        160        170        180 
IDYGPVQQEL YVHIVCDPDH PDYEAMKEAG VLSTEYDPDW AGAFVIEDSR EGWAAALVDL 

       190        200        210        220        230        240 
IDTHYRDEVS HFQRVYDVSR VRQFGAKLKT FGGTASGPLP LARMLIDVCE ILSEIATEGG 

       250        260        270        280        290        300 
QLTGIAAMEI DHAIAQCVVA GGVRRSARMS MMHWKDPQVY EFLRIKQDTG SHWTTNISLE 

       310        320        330        340        350        360 
VDDEFWVAVE EGWAGPNNRI LRELTEGMVA NGEPGFWNSS LSNVGEPNEV VCTNPCGEIT 

       370        380        390        400        410        420 
LEPWEPCNLG HVNLAAFAHG NGSYDITGLY RAHRLVTRFL MRATFSPVAD PKSREVLDRN 

       430        440        450        460        470        480 
RRIGVGHLGV ASFLALCGWK YSEARTNEEF KWLLRSLAEE VDHAATQFAH QLRIPVPVKK 

       490        500        510        520        530        540 
RTVAPTGTIA KMPGVSEGIH PIFSRYFIRR VRLSMSDPDQ TRMLADYGRQ GYEVEDDLYA 

       550        560        570        580        590        600 
KFTGVVSIPT QDTLVAEVIE HYGQDSESLV ESAADLSLNE LLGFQALYQT IWADNAVSFT 

       610        620        630        640        650        660 
ANVDPETYNA DDVRQQLRLF GGLLKGATIF PEASMPQAPY ERITKEQYEQ ATAKAVADGV 

       670 
DEDCANGACP IR 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AY129332 Genomic DNA. Translation: AAN01804.1.
RefSeqNP_817639.1. NC_004682.1.

3D structure databases

ProteinModelPortalQ857H2.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID1259263.

Family and domain databases

InterProIPR000788. RNR_lg_C.
IPR013345. RTP_Rdtase_AdoCbl-dep.
[Graphical view]
PfamPF02867. Ribonuc_red_lgC. 3 hits.
[Graphical view]
TIGRFAMsTIGR02505. RTPR. 1 hit.
ProtoNetSearch...

Entry information

Entry nameVG50_BPMB2
AccessionPrimary (citable) accession number: Q857H2
Entry history
Integrated into UniProtKB/Swiss-Prot: September 19, 2003
Last sequence update: June 1, 2003
Last modified: May 14, 2014
This is version 58 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families