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Q84YK8

- LOXC2_ORYSJ

UniProt

Q84YK8 - LOXC2_ORYSJ

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Protein

Probable lipoxygenase 8, chloroplastic

Gene

CM-LOX2

Organism
Oryza sativa subsp. japonica (Rice)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli

Functioni

Plant lipoxygenase may be involved in a number of diverse aspects of plant physiology including growth and development, pest resistance, and senescence or responses to wounding. It catalyzes the hydroperoxidation of lipids containing a cis,cis-1,4-pentadiene structure (By similarity).By similarity

Catalytic activityi

Linoleate + O2 = (9Z,11E,13S)-13-hydroperoxyoctadeca-9,11-dienoate.
Alpha-linolenate + O2 = (9Z,11E,13S,15Z)-13-hydroperoxyoctadeca-9,11,15-trienoate.

Cofactori

Binds 1 iron ion per subunit. Iron is tightly bound (By similarity).PROSITE-ProRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi598 – 5981Iron; catalyticPROSITE-ProRule annotation
Metal bindingi603 – 6031Iron; catalyticPROSITE-ProRule annotation
Metal bindingi790 – 7901Iron; catalyticPROSITE-ProRule annotation
Metal bindingi794 – 7941Iron; catalyticPROSITE-ProRule annotation
Metal bindingi941 – 9411Iron; via carboxylate; catalyticPROSITE-ProRule annotation

GO - Molecular functioni

  1. iron ion binding Source: InterPro
  2. linoleate 13S-lipoxygenase activity Source: UniProtKB-EC

GO - Biological processi

  1. oxylipin biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Dioxygenase, Oxidoreductase

Keywords - Biological processi

Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Oxylipin biosynthesis

Keywords - Ligandi

Iron, Metal-binding

Enzyme and pathway databases

UniPathwayiUPA00382.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable lipoxygenase 8, chloroplastic (EC:1.13.11.12)
Gene namesi
Name:CM-LOX2
Ordered Locus Names:Os08g0509100, LOC_Os08g39850
ORF Names:B1168A08.28-1, B1168A08.28-2, OSJNBa0016N23.103-1, OSJNBa0016N23.103-2
OrganismiOryza sativa subsp. japonica (Rice)
Taxonomic identifieri39947 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBEP cladeEhrhartoideaeOryzeaeOryza
ProteomesiUP000000763: Chromosome 8

Organism-specific databases

GrameneiQ84YK8.

Subcellular locationi

Plastidchloroplast Curated

GO - Cellular componenti

  1. chloroplast Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Chloroplast, Plastid

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transit peptidei1 – 6767ChloroplastSequence AnalysisAdd
BLAST
Chaini68 – 941874Probable lipoxygenase 8, chloroplasticPRO_0000018328Add
BLAST

Proteomic databases

PRIDEiQ84YK8.

Expressioni

Gene expression databases

ExpressionAtlasiQ84YK8. baseline.

Structurei

3D structure databases

ProteinModelPortaliQ84YK8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini100 – 236137PLATPROSITE-ProRule annotationAdd
BLAST
Domaini242 – 941700LipoxygenasePROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Belongs to the lipoxygenase family.Curated
Contains 1 lipoxygenase domain.PROSITE-ProRule annotation
Contains 1 PLAT domain.PROSITE-ProRule annotation

Keywords - Domaini

Transit peptide

Phylogenomic databases

eggNOGiNOG69653.
HOGENOMiHOG000230469.
InParanoidiQ84YK8.
KOiK00454.
OMAiTEMFLED.

Family and domain databases

Gene3Di2.60.60.20. 1 hit.
4.10.372.10. 1 hit.
InterProiIPR008976. Lipase_LipOase.
IPR000907. LipOase.
IPR013819. LipOase_C.
IPR020834. LipOase_CS.
IPR020833. LipOase_Fe_BS.
IPR001246. LipOase_pln.
IPR027433. Lipoxygenase_domain_3.
IPR001024. PLAT/LH2_dom.
[Graphical view]
PANTHERiPTHR11771. PTHR11771. 1 hit.
PfamiPF00305. Lipoxygenase. 1 hit.
PF01477. PLAT. 1 hit.
[Graphical view]
PRINTSiPR00087. LIPOXYGENASE.
PR00468. PLTLPOXGNASE.
SMARTiSM00308. LH2. 1 hit.
[Graphical view]
SUPFAMiSSF48484. SSF48484. 1 hit.
SSF49723. SSF49723. 1 hit.
PROSITEiPS00711. LIPOXYGENASE_1. 1 hit.
PS00081. LIPOXYGENASE_2. 1 hit.
PS51393. LIPOXYGENASE_3. 1 hit.
PS50095. PLAT. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q84YK8-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MLRPQLNPSS SHHHTTTTSS SSSTQLYFAS SSCIASLRRP SPPSLIAGAG
60 70 80 90 100
CRTTRRRQQG RQRVVVRCAS SSAASSASEA ARRGTGSSDM APAAVVKVKA
110 120 130 140 150
VATIKVTVEG LLNSLRPSKA IDNIRDLIGR SLFLELVSSE LEAKTGKKKA
160 170 180 190 200
TVHSYAHKVD DDDHGVVTYE ADFDVPTGFG PIGAVVVTNE LGQEMFLEDL
210 220 230 240 250
NLTAGDGAGN STVLPIRCNS WVQPKSSIDE GTPGKRIFFA KAYLPGQTPA
260 270 280 290 300
GLRSYREEDL KQKRGNGAGQ READDRVYDY DVYNDLGNPD SNGDLARPVL
310 320 330 340 350
GGSKQFPYPR RCRTGRPPSK KDPKSETRKG NVYVPRDEEF SEVKNAQFLL
360 370 380 390 400
KTLQSVLHAA VPAAQSALID NLSLNLPFPS FFVIDKLFED GVELPGVEKL
410 420 430 440 450
GFLHSIVPRL LELLRDSPGD KILLFDTPAN VQKDKFAWLR DEEFARETLA
460 470 480 490 500
GINPYAIELV REFPLKSKLD PAVYGPAESA ITADLLEEQM RRVMTVEEAI
510 520 530 540 550
SQKRLFMLDF HDLFLPYVHK IRSLKHTTMY GSRTIFFLTD DGTLRLLAIE
560 570 580 590 600
LTRPASPSQP QWRQVFTPST DTTKSWLWRM AKAHVRAHDA GHHELITHWL
610 620 630 640 650
RTHCAVEPYI IAANRQLSEM HPIYQLLHPH FRYTMRINAL ARSRLISAAG
660 670 680 690 700
IIELSFSPQK YSMELSSVAY DKLWRFDMEA LPADLVRRGM AEEDPTAEHG
710 720 730 740 750
LRLAIEDYPF ANDGLLIWDA IKTWVQAYVA RFYPDADSVA GDEELQAFWT
760 770 780 790 800
EVRTKGHGDK KDAPWWPKLD SPESLAHTLT TIVWVAAAHH AAVNFGQYDF
810 820 830 840 850
GGYFPNRPSI ARTVMPVEEP VDGAAMERFL DNPDQALREC FPSQVQATVV
860 870 880 890 900
MAVLDVLSTH STDEEYLGGE QTRPWNSDAA VQAAYAGFTA RLKEIEGVID
910 920 930 940
GRNKDRKLKN RCGAGILPYQ LMKPFSDAGV TGMGIPNSTS I
Length:941
Mass (Da):104,494
Last modified:June 1, 2003 - v1
Checksum:iBE3C7BA515137C32
GO

Sequence cautioni

The sequence BAD10669.1 differs from that shown. Reason: Erroneous gene model prediction.
The sequence BAD10729.1 differs from that shown. Reason: Erroneous gene model prediction.

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti590 – 5901A → T in AAD42043. 1 PublicationCurated
Sequence conflicti639 – 6391A → T in AAD42043. 1 PublicationCurated
Sequence conflicti711 – 7111A → T in AAD42043. 1 PublicationCurated

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AP005816 Genomic DNA. Translation: BAD10668.1.
AP005816 Genomic DNA. Translation: BAD10669.1. Sequence problems.
AP006049 Genomic DNA. Translation: BAC57390.1.
AP006049 Genomic DNA. Translation: BAD10729.1. Sequence problems.
AF095896 mRNA. Translation: AAD42043.1.
RefSeqiNP_001062200.1. NM_001068735.1.
UniGeneiOs.13008.

Genome annotation databases

EnsemblPlantsiOS08T0509100-01; OS08T0509100-01; OS08G0509100.
GeneIDi4345994.
KEGGiosa:4345994.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AP005816 Genomic DNA. Translation: BAD10668.1 .
AP005816 Genomic DNA. Translation: BAD10669.1 . Sequence problems.
AP006049 Genomic DNA. Translation: BAC57390.1 .
AP006049 Genomic DNA. Translation: BAD10729.1 . Sequence problems.
AF095896 mRNA. Translation: AAD42043.1 .
RefSeqi NP_001062200.1. NM_001068735.1.
UniGenei Os.13008.

3D structure databases

ProteinModelPortali Q84YK8.
ModBasei Search...
MobiDBi Search...

Proteomic databases

PRIDEi Q84YK8.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblPlantsi OS08T0509100-01 ; OS08T0509100-01 ; OS08G0509100 .
GeneIDi 4345994.
KEGGi osa:4345994.

Organism-specific databases

Gramenei Q84YK8.

Phylogenomic databases

eggNOGi NOG69653.
HOGENOMi HOG000230469.
InParanoidi Q84YK8.
KOi K00454.
OMAi TEMFLED.

Enzyme and pathway databases

UniPathwayi UPA00382 .

Gene expression databases

ExpressionAtlasi Q84YK8. baseline.

Family and domain databases

Gene3Di 2.60.60.20. 1 hit.
4.10.372.10. 1 hit.
InterProi IPR008976. Lipase_LipOase.
IPR000907. LipOase.
IPR013819. LipOase_C.
IPR020834. LipOase_CS.
IPR020833. LipOase_Fe_BS.
IPR001246. LipOase_pln.
IPR027433. Lipoxygenase_domain_3.
IPR001024. PLAT/LH2_dom.
[Graphical view ]
PANTHERi PTHR11771. PTHR11771. 1 hit.
Pfami PF00305. Lipoxygenase. 1 hit.
PF01477. PLAT. 1 hit.
[Graphical view ]
PRINTSi PR00087. LIPOXYGENASE.
PR00468. PLTLPOXGNASE.
SMARTi SM00308. LH2. 1 hit.
[Graphical view ]
SUPFAMi SSF48484. SSF48484. 1 hit.
SSF49723. SSF49723. 1 hit.
PROSITEi PS00711. LIPOXYGENASE_1. 1 hit.
PS00081. LIPOXYGENASE_2. 1 hit.
PS51393. LIPOXYGENASE_3. 1 hit.
PS50095. PLAT. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Nipponbare.
  2. "Purification and cDNA cloning of two rice lipoxygenases induced by blast fungus."
    Peng Y., Hou Z.
    Submitted (OCT-1998) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 259-941.
    Strain: cv. Aichiasahi.
    Tissue: Seedling leaf.

Entry informationi

Entry nameiLOXC2_ORYSJ
AccessioniPrimary (citable) accession number: Q84YK8
Secondary accession number(s): Q7EXZ6, Q9XHM6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: August 30, 2005
Last sequence update: June 1, 2003
Last modified: October 29, 2014
This is version 76 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. Oryza sativa (rice)
    Index of Oryza sativa entries and their corresponding gene designations
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3