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Q84YK8 (LOXC2_ORYSJ) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 74. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable lipoxygenase 8, chloroplastic

EC=1.13.11.12
Gene names
Name:CM-LOX2
Ordered Locus Names:Os08g0509100, LOC_Os08g39850
ORF Names:B1168A08.28-1, B1168A08.28-2, OSJNBa0016N23.103-1, OSJNBa0016N23.103-2
OrganismOryza sativa subsp. japonica (Rice) [Reference proteome]
Taxonomic identifier39947 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBEP cladeEhrhartoideaeOryzeaeOryza

Protein attributes

Sequence length941 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

Plant lipoxygenase may be involved in a number of diverse aspects of plant physiology including growth and development, pest resistance, and senescence or responses to wounding. It catalyzes the hydroperoxidation of lipids containing a cis,cis-1,4-pentadiene structure By similarity.

Catalytic activity

Linoleate + O2 = (9Z,11E,13S)-13-hydroperoxyoctadeca-9,11-dienoate.

Alpha-linolenate + O2 = (9Z,11E,13S,15Z)-13-hydroperoxyoctadeca-9,11,15-trienoate.

Cofactor

Binds 1 iron ion per subunit. Iron is tightly bound By similarity.

Pathway

Lipid metabolism; oxylipin biosynthesis.

Subcellular location

Plastidchloroplast Potential.

Sequence similarities

Belongs to the lipoxygenase family.

Contains 1 lipoxygenase domain.

Contains 1 PLAT domain.

Sequence caution

The sequence BAD10669.1 differs from that shown. Reason: Erroneous gene model prediction.

The sequence BAD10729.1 differs from that shown. Reason: Erroneous gene model prediction.

Ontologies

Keywords
   Biological processFatty acid biosynthesis
Fatty acid metabolism
Lipid biosynthesis
Lipid metabolism
Oxylipin biosynthesis
   Cellular componentChloroplast
Plastid
   DomainTransit peptide
   LigandIron
Metal-binding
   Molecular functionDioxygenase
Oxidoreductase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processoxylipin biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-UniPathway

   Cellular_componentchloroplast

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functioniron ion binding

Inferred from electronic annotation. Source: InterPro

linoleate 13S-lipoxygenase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Transit peptide1 – 6767Chloroplast Potential
Chain68 – 941874Probable lipoxygenase 8, chloroplastic
PRO_0000018328

Regions

Domain100 – 236137PLAT
Domain242 – 941700Lipoxygenase

Sites

Metal binding5981Iron; catalytic By similarity
Metal binding6031Iron; catalytic By similarity
Metal binding7901Iron; catalytic By similarity
Metal binding7941Iron; catalytic By similarity
Metal binding9411Iron; via carboxylate; catalytic By similarity

Experimental info

Sequence conflict5901A → T in AAD42043. Ref.2
Sequence conflict6391A → T in AAD42043. Ref.2
Sequence conflict7111A → T in AAD42043. Ref.2

Sequences

Sequence LengthMass (Da)Tools
Q84YK8 [UniParc].

Last modified June 1, 2003. Version 1.
Checksum: BE3C7BA515137C32

FASTA941104,494
        10         20         30         40         50         60 
MLRPQLNPSS SHHHTTTTSS SSSTQLYFAS SSCIASLRRP SPPSLIAGAG CRTTRRRQQG 

        70         80         90        100        110        120 
RQRVVVRCAS SSAASSASEA ARRGTGSSDM APAAVVKVKA VATIKVTVEG LLNSLRPSKA 

       130        140        150        160        170        180 
IDNIRDLIGR SLFLELVSSE LEAKTGKKKA TVHSYAHKVD DDDHGVVTYE ADFDVPTGFG 

       190        200        210        220        230        240 
PIGAVVVTNE LGQEMFLEDL NLTAGDGAGN STVLPIRCNS WVQPKSSIDE GTPGKRIFFA 

       250        260        270        280        290        300 
KAYLPGQTPA GLRSYREEDL KQKRGNGAGQ READDRVYDY DVYNDLGNPD SNGDLARPVL 

       310        320        330        340        350        360 
GGSKQFPYPR RCRTGRPPSK KDPKSETRKG NVYVPRDEEF SEVKNAQFLL KTLQSVLHAA 

       370        380        390        400        410        420 
VPAAQSALID NLSLNLPFPS FFVIDKLFED GVELPGVEKL GFLHSIVPRL LELLRDSPGD 

       430        440        450        460        470        480 
KILLFDTPAN VQKDKFAWLR DEEFARETLA GINPYAIELV REFPLKSKLD PAVYGPAESA 

       490        500        510        520        530        540 
ITADLLEEQM RRVMTVEEAI SQKRLFMLDF HDLFLPYVHK IRSLKHTTMY GSRTIFFLTD 

       550        560        570        580        590        600 
DGTLRLLAIE LTRPASPSQP QWRQVFTPST DTTKSWLWRM AKAHVRAHDA GHHELITHWL 

       610        620        630        640        650        660 
RTHCAVEPYI IAANRQLSEM HPIYQLLHPH FRYTMRINAL ARSRLISAAG IIELSFSPQK 

       670        680        690        700        710        720 
YSMELSSVAY DKLWRFDMEA LPADLVRRGM AEEDPTAEHG LRLAIEDYPF ANDGLLIWDA 

       730        740        750        760        770        780 
IKTWVQAYVA RFYPDADSVA GDEELQAFWT EVRTKGHGDK KDAPWWPKLD SPESLAHTLT 

       790        800        810        820        830        840 
TIVWVAAAHH AAVNFGQYDF GGYFPNRPSI ARTVMPVEEP VDGAAMERFL DNPDQALREC 

       850        860        870        880        890        900 
FPSQVQATVV MAVLDVLSTH STDEEYLGGE QTRPWNSDAA VQAAYAGFTA RLKEIEGVID 

       910        920        930        940 
GRNKDRKLKN RCGAGILPYQ LMKPFSDAGV TGMGIPNSTS I 

« Hide

References

« Hide 'large scale' references
[1]"The map-based sequence of the rice genome."
International rice genome sequencing project (IRGSP)
Nature 436:793-800(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Nipponbare.
[2]"Purification and cDNA cloning of two rice lipoxygenases induced by blast fungus."
Peng Y., Hou Z.
Submitted (OCT-1998) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 259-941.
Strain: cv. Aichiasahi.
Tissue: Seedling leaf.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AP005816 Genomic DNA. Translation: BAD10668.1.
AP005816 Genomic DNA. Translation: BAD10669.1. Sequence problems.
AP006049 Genomic DNA. Translation: BAC57390.1.
AP006049 Genomic DNA. Translation: BAD10729.1. Sequence problems.
AF095896 mRNA. Translation: AAD42043.1.
RefSeqNP_001062200.1. NM_001068735.1.
UniGeneOs.13008.

3D structure databases

ProteinModelPortalQ84YK8.
ModBaseSearch...
MobiDBSearch...

Proteomic databases

PRIDEQ84YK8.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsOS08T0509100-01; OS08T0509100-01; OS08G0509100.
GeneID4345994.
KEGGosa:4345994.

Organism-specific databases

GrameneQ84YK8.

Phylogenomic databases

eggNOGNOG69653.
HOGENOMHOG000230469.
KOK00454.
OMATEMFLED.

Enzyme and pathway databases

UniPathwayUPA00382.

Family and domain databases

Gene3D2.60.60.20. 1 hit.
4.10.372.10. 1 hit.
InterProIPR008976. Lipase_LipOase.
IPR000907. LipOase.
IPR013819. LipOase_C.
IPR020834. LipOase_CS.
IPR020833. LipOase_Fe_BS.
IPR001246. LipOase_pln.
IPR027433. Lipoxygenase_domain_3.
IPR001024. PLAT/LH2_dom.
[Graphical view]
PANTHERPTHR11771. PTHR11771. 1 hit.
PfamPF00305. Lipoxygenase. 1 hit.
PF01477. PLAT. 1 hit.
[Graphical view]
PRINTSPR00087. LIPOXYGENASE.
PR00468. PLTLPOXGNASE.
SMARTSM00308. LH2. 1 hit.
[Graphical view]
SUPFAMSSF48484. SSF48484. 1 hit.
SSF49723. SSF49723. 1 hit.
PROSITEPS00711. LIPOXYGENASE_1. 1 hit.
PS00081. LIPOXYGENASE_2. 1 hit.
PS51393. LIPOXYGENASE_3. 1 hit.
PS50095. PLAT. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameLOXC2_ORYSJ
AccessionPrimary (citable) accession number: Q84YK8
Secondary accession number(s): Q7EXZ6, Q9XHM6
Entry history
Integrated into UniProtKB/Swiss-Prot: August 30, 2005
Last sequence update: June 1, 2003
Last modified: May 14, 2014
This is version 74 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Oryza sativa (rice)

Index of Oryza sativa entries and their corresponding gene designations

PATHWAY comments

Index of metabolic and biosynthesis pathways