Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q84YK8

- LOXC2_ORYSJ

UniProt

Q84YK8 - LOXC2_ORYSJ

Protein

Probable lipoxygenase 8, chloroplastic

Gene

CM-LOX2

Organism
Oryza sativa subsp. japonica (Rice)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 75 (01 Oct 2014)
      Sequence version 1 (01 Jun 2003)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Plant lipoxygenase may be involved in a number of diverse aspects of plant physiology including growth and development, pest resistance, and senescence or responses to wounding. It catalyzes the hydroperoxidation of lipids containing a cis,cis-1,4-pentadiene structure By similarity.By similarity

    Catalytic activityi

    Linoleate + O2 = (9Z,11E,13S)-13-hydroperoxyoctadeca-9,11-dienoate.
    Alpha-linolenate + O2 = (9Z,11E,13S,15Z)-13-hydroperoxyoctadeca-9,11,15-trienoate.

    Cofactori

    Binds 1 iron ion per subunit. Iron is tightly bound By similarity.PROSITE-ProRule annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Metal bindingi598 – 5981Iron; catalyticPROSITE-ProRule annotation
    Metal bindingi603 – 6031Iron; catalyticPROSITE-ProRule annotation
    Metal bindingi790 – 7901Iron; catalyticPROSITE-ProRule annotation
    Metal bindingi794 – 7941Iron; catalyticPROSITE-ProRule annotation
    Metal bindingi941 – 9411Iron; via carboxylate; catalyticPROSITE-ProRule annotation

    GO - Molecular functioni

    1. iron ion binding Source: InterPro
    2. linoleate 13S-lipoxygenase activity Source: UniProtKB-EC

    GO - Biological processi

    1. oxylipin biosynthetic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    Dioxygenase, Oxidoreductase

    Keywords - Biological processi

    Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Oxylipin biosynthesis

    Keywords - Ligandi

    Iron, Metal-binding

    Enzyme and pathway databases

    UniPathwayiUPA00382.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Probable lipoxygenase 8, chloroplastic (EC:1.13.11.12)
    Gene namesi
    Name:CM-LOX2
    Ordered Locus Names:Os08g0509100, LOC_Os08g39850
    ORF Names:B1168A08.28-1, B1168A08.28-2, OSJNBa0016N23.103-1, OSJNBa0016N23.103-2
    OrganismiOryza sativa subsp. japonica (Rice)
    Taxonomic identifieri39947 [NCBI]
    Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBEP cladeEhrhartoideaeOryzeaeOryza
    ProteomesiUP000000763: Chromosome 8

    Organism-specific databases

    GrameneiQ84YK8.

    Subcellular locationi

    Plastidchloroplast Curated

    GO - Cellular componenti

    1. chloroplast Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Chloroplast, Plastid

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transit peptidei1 – 6767ChloroplastSequence AnalysisAdd
    BLAST
    Chaini68 – 941874Probable lipoxygenase 8, chloroplasticPRO_0000018328Add
    BLAST

    Proteomic databases

    PRIDEiQ84YK8.

    Structurei

    3D structure databases

    ProteinModelPortaliQ84YK8.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini100 – 236137PLATPROSITE-ProRule annotationAdd
    BLAST
    Domaini242 – 941700LipoxygenasePROSITE-ProRule annotationAdd
    BLAST

    Sequence similaritiesi

    Belongs to the lipoxygenase family.Curated
    Contains 1 lipoxygenase domain.PROSITE-ProRule annotation
    Contains 1 PLAT domain.PROSITE-ProRule annotation

    Keywords - Domaini

    Transit peptide

    Phylogenomic databases

    eggNOGiNOG69653.
    HOGENOMiHOG000230469.
    KOiK00454.
    OMAiTEMFLED.

    Family and domain databases

    Gene3Di2.60.60.20. 1 hit.
    4.10.372.10. 1 hit.
    InterProiIPR008976. Lipase_LipOase.
    IPR000907. LipOase.
    IPR013819. LipOase_C.
    IPR020834. LipOase_CS.
    IPR020833. LipOase_Fe_BS.
    IPR001246. LipOase_pln.
    IPR027433. Lipoxygenase_domain_3.
    IPR001024. PLAT/LH2_dom.
    [Graphical view]
    PANTHERiPTHR11771. PTHR11771. 1 hit.
    PfamiPF00305. Lipoxygenase. 1 hit.
    PF01477. PLAT. 1 hit.
    [Graphical view]
    PRINTSiPR00087. LIPOXYGENASE.
    PR00468. PLTLPOXGNASE.
    SMARTiSM00308. LH2. 1 hit.
    [Graphical view]
    SUPFAMiSSF48484. SSF48484. 1 hit.
    SSF49723. SSF49723. 1 hit.
    PROSITEiPS00711. LIPOXYGENASE_1. 1 hit.
    PS00081. LIPOXYGENASE_2. 1 hit.
    PS51393. LIPOXYGENASE_3. 1 hit.
    PS50095. PLAT. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    Q84YK8-1 [UniParc]FASTAAdd to Basket

    « Hide

    MLRPQLNPSS SHHHTTTTSS SSSTQLYFAS SSCIASLRRP SPPSLIAGAG    50
    CRTTRRRQQG RQRVVVRCAS SSAASSASEA ARRGTGSSDM APAAVVKVKA 100
    VATIKVTVEG LLNSLRPSKA IDNIRDLIGR SLFLELVSSE LEAKTGKKKA 150
    TVHSYAHKVD DDDHGVVTYE ADFDVPTGFG PIGAVVVTNE LGQEMFLEDL 200
    NLTAGDGAGN STVLPIRCNS WVQPKSSIDE GTPGKRIFFA KAYLPGQTPA 250
    GLRSYREEDL KQKRGNGAGQ READDRVYDY DVYNDLGNPD SNGDLARPVL 300
    GGSKQFPYPR RCRTGRPPSK KDPKSETRKG NVYVPRDEEF SEVKNAQFLL 350
    KTLQSVLHAA VPAAQSALID NLSLNLPFPS FFVIDKLFED GVELPGVEKL 400
    GFLHSIVPRL LELLRDSPGD KILLFDTPAN VQKDKFAWLR DEEFARETLA 450
    GINPYAIELV REFPLKSKLD PAVYGPAESA ITADLLEEQM RRVMTVEEAI 500
    SQKRLFMLDF HDLFLPYVHK IRSLKHTTMY GSRTIFFLTD DGTLRLLAIE 550
    LTRPASPSQP QWRQVFTPST DTTKSWLWRM AKAHVRAHDA GHHELITHWL 600
    RTHCAVEPYI IAANRQLSEM HPIYQLLHPH FRYTMRINAL ARSRLISAAG 650
    IIELSFSPQK YSMELSSVAY DKLWRFDMEA LPADLVRRGM AEEDPTAEHG 700
    LRLAIEDYPF ANDGLLIWDA IKTWVQAYVA RFYPDADSVA GDEELQAFWT 750
    EVRTKGHGDK KDAPWWPKLD SPESLAHTLT TIVWVAAAHH AAVNFGQYDF 800
    GGYFPNRPSI ARTVMPVEEP VDGAAMERFL DNPDQALREC FPSQVQATVV 850
    MAVLDVLSTH STDEEYLGGE QTRPWNSDAA VQAAYAGFTA RLKEIEGVID 900
    GRNKDRKLKN RCGAGILPYQ LMKPFSDAGV TGMGIPNSTS I 941
    Length:941
    Mass (Da):104,494
    Last modified:June 1, 2003 - v1
    Checksum:iBE3C7BA515137C32
    GO

    Sequence cautioni

    The sequence BAD10669.1 differs from that shown. Reason: Erroneous gene model prediction.
    The sequence BAD10729.1 differs from that shown. Reason: Erroneous gene model prediction.

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti590 – 5901A → T in AAD42043. 1 PublicationCurated
    Sequence conflicti639 – 6391A → T in AAD42043. 1 PublicationCurated
    Sequence conflicti711 – 7111A → T in AAD42043. 1 PublicationCurated

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AP005816 Genomic DNA. Translation: BAD10668.1.
    AP005816 Genomic DNA. Translation: BAD10669.1. Sequence problems.
    AP006049 Genomic DNA. Translation: BAC57390.1.
    AP006049 Genomic DNA. Translation: BAD10729.1. Sequence problems.
    AF095896 mRNA. Translation: AAD42043.1.
    RefSeqiNP_001062200.1. NM_001068735.1.
    UniGeneiOs.13008.

    Genome annotation databases

    EnsemblPlantsiOS08T0509100-01; OS08T0509100-01; OS08G0509100.
    GeneIDi4345994.
    KEGGiosa:4345994.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AP005816 Genomic DNA. Translation: BAD10668.1 .
    AP005816 Genomic DNA. Translation: BAD10669.1 . Sequence problems.
    AP006049 Genomic DNA. Translation: BAC57390.1 .
    AP006049 Genomic DNA. Translation: BAD10729.1 . Sequence problems.
    AF095896 mRNA. Translation: AAD42043.1 .
    RefSeqi NP_001062200.1. NM_001068735.1.
    UniGenei Os.13008.

    3D structure databases

    ProteinModelPortali Q84YK8.
    ModBasei Search...
    MobiDBi Search...

    Proteomic databases

    PRIDEi Q84YK8.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblPlantsi OS08T0509100-01 ; OS08T0509100-01 ; OS08G0509100 .
    GeneIDi 4345994.
    KEGGi osa:4345994.

    Organism-specific databases

    Gramenei Q84YK8.

    Phylogenomic databases

    eggNOGi NOG69653.
    HOGENOMi HOG000230469.
    KOi K00454.
    OMAi TEMFLED.

    Enzyme and pathway databases

    UniPathwayi UPA00382 .

    Family and domain databases

    Gene3Di 2.60.60.20. 1 hit.
    4.10.372.10. 1 hit.
    InterProi IPR008976. Lipase_LipOase.
    IPR000907. LipOase.
    IPR013819. LipOase_C.
    IPR020834. LipOase_CS.
    IPR020833. LipOase_Fe_BS.
    IPR001246. LipOase_pln.
    IPR027433. Lipoxygenase_domain_3.
    IPR001024. PLAT/LH2_dom.
    [Graphical view ]
    PANTHERi PTHR11771. PTHR11771. 1 hit.
    Pfami PF00305. Lipoxygenase. 1 hit.
    PF01477. PLAT. 1 hit.
    [Graphical view ]
    PRINTSi PR00087. LIPOXYGENASE.
    PR00468. PLTLPOXGNASE.
    SMARTi SM00308. LH2. 1 hit.
    [Graphical view ]
    SUPFAMi SSF48484. SSF48484. 1 hit.
    SSF49723. SSF49723. 1 hit.
    PROSITEi PS00711. LIPOXYGENASE_1. 1 hit.
    PS00081. LIPOXYGENASE_2. 1 hit.
    PS51393. LIPOXYGENASE_3. 1 hit.
    PS50095. PLAT. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: cv. Nipponbare.
    2. "Purification and cDNA cloning of two rice lipoxygenases induced by blast fungus."
      Peng Y., Hou Z.
      Submitted (OCT-1998) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 259-941.
      Strain: cv. Aichiasahi.
      Tissue: Seedling leaf.

    Entry informationi

    Entry nameiLOXC2_ORYSJ
    AccessioniPrimary (citable) accession number: Q84YK8
    Secondary accession number(s): Q7EXZ6, Q9XHM6
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: August 30, 2005
    Last sequence update: June 1, 2003
    Last modified: October 1, 2014
    This is version 75 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programPlant Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. Oryza sativa (rice)
      Index of Oryza sativa entries and their corresponding gene designations
    3. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3