Q84WW1 (FB140_ARATH) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
F-box protein At3g12350

Gene names

Ordered Locus Names:	At3g12350
ORF Names:	MQC3.17, T2E22.32

Organism

Arabidopsis thaliana (Mouse-ear cress)

Taxonomic identifier

3702 [NCBI]

Taxonomic lineage

Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › rosids › malvids › Brassicales › Brassicaceae › Camelineae › Arabidopsis

Protein attributes

Sequence length	422 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Sequence similarities	Contains 1 F-box domain.
Sequence caution	The sequence AAG51006.1 differs from that shown. Reason: Erroneous gene model prediction. The sequence BAB03143.1 differs from that shown. Reason: Erroneous gene model prediction. The predicted gene At3g12350 has been split into 2 genes: At3g12350 and At3g12360.

Ontologies

Keywords
Coding sequence diversity	Alternative splicing
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
None. [Check GOA]

Alternative products

This entry describes 1 isoform produced by alternative splicing. [Select]

Note: A number of isoforms are produced. According to EST sequences.

Isoform 1 (identifier: Q84WW1-1)

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 422	422	F-box protein At3g12350		PRO_0000274951
Regions
	Domain	5 – 52	48	F-box
Experimental info
	Sequence conflict	274	1	G → C in AAM63646. Ref.5
	Sequence conflict	284	1	I → M in AAM63646. Ref.5

Sequences

	Sequence		Length	Mass (Da)
	Isoform 1 [UniParc]. Last modified June 1, 2003. Version 1. Checksum: 13C8580242432D0A	FASTA	422	47,756
	10 20 30 40 50 60 MATFALPFCE IPEDLQLRIL SLLTPAEISS FACTSKRFAS LCQEDGKIWH VMCDQRWGKK 70 80 90 100 110 120 TKIQKWANGQ IPYRHLYKTL KGLENLIGFW RLCGRANPAA SSPPLVFFDW GSSFILGSRV 130 140 150 160 170 180 LSTGDDTYEV KKTPFLLMGI SPEGRSENFL DLVGGNLRSV DDDLKELEAS NNLVSVDVNF 190 200 210 220 230 240 MGNGHIMVEE NRCFTNNNRR EDQRSSGDES DDLISSPNFS EMYTQLANKT SPGGDRRRQK 250 260 270 280 290 300 RKEKERQASR TKWEPEHFLK VADCSPTPTR PLQGLWKGFC EGSIELYLVK YDEVGGIICR 310 320 330 340 350 360 KVEDLSLSRY TPPVFWTPKH TFIRSPFSAE EELLLNSRIH ISPFAEVHEN VVSGMLYMKS 370 380 390 400 410 420 SCDLVLPGEP GNGIGFLRGE GRVWLYDNGT FGFGFLRDQF IIDLKRVALE DGCLADEVEA CM

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Structural analysis of Arabidopsis thaliana chromosome 3. II. Sequence features of the 4,251,695 bp regions covered by 90 P1, TAC and BAC clones." Kaneko T., Katoh T., Sato S., Nakamura Y., Asamizu E., Tabata S. DNA Res. 7:217-221(2000) [PubMed: 10907853] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. Columbia.
[2]	"Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana." Salanoubat M., Lemcke K., Rieger M., Ansorge W., Unseld M., Fartmann B., Valle G., Bloecker H., Perez-Alonso M., Obermaier B., Delseny M., Boutry M., Grivell L.A., Mache R., Puigdomenech P., De Simone V., Choisne N., Artiguenave F. , Robert C., Brottier P., Wincker P., Cattolico L., Weissenbach J., Saurin W., Quetier F., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Benes V., Wurmbach E., Drzonek H., Erfle H., Jordan N., Bangert S., Wiedelmann R., Kranz H., Voss H., Holland R., Brandt P., Nyakatura G., Vezzi A., D'Angelo M., Pallavicini A., Toppo S., Simionati B., Conrad A., Hornischer K., Kauer G., Loehnert T.-H., Nordsiek G., Reichelt J., Scharfe M., Schoen O., Bargues M., Terol J., Climent J., Navarro P., Collado C., Perez-Perez A., Ottenwaelder B., Duchemin D., Cooke R., Laudie M., Berger-Llauro C., Purnelle B., Masuy D., de Haan M., Maarse A.C., Alcaraz J.-P., Cottet A., Casacuberta E., Monfort A., Argiriou A., Flores M., Liguori R., Vitale D., Mannhaupt G., Haase D., Schoof H., Rudd S., Zaccaria P., Mewes H.-W., Mayer K.F.X., Kaul S., Town C.D., Koo H.L., Tallon L.J., Jenkins J., Rooney T., Rizzo M., Walts A., Utterback T., Fujii C.Y., Shea T.P., Creasy T.H., Haas B., Maiti R., Wu D., Peterson J., Van Aken S., Pai G., Militscher J., Sellers P., Gill J.E., Feldblyum T.V., Preuss D., Lin X., Nierman W.C., Salzberg S.L., White O., Venter J.C., Fraser C.M., Kaneko T., Nakamura Y., Sato S., Kato T., Asamizu E., Sasamoto S., Kimura T., Idesawa K., Kawashima K., Kishida Y., Kiyokawa C., Kohara M., Matsumoto M., Matsuno A., Muraki A., Nakayama S., Nakazaki N., Shinpo S., Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S. Nature 408:820-822(2000) [PubMed: 11130713] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. Columbia.
[3]	The Arabidopsis Information Resource (TAIR) Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases Cited for: GENOME REANNOTATION. Strain: cv. Columbia.
[4]	"Empirical analysis of transcriptional activity in the Arabidopsis genome." Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G. , Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R. Science 302:842-846(2003) [PubMed: 14593172] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Strain: cv. Columbia.
[5]	"Full-length cDNA from Arabidopsis thaliana." Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B., Feldmann K.A. Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
+	Additional computationally mapped references.

Web resources

PlantsUBQ

A functional genomics database for the ubiquitin/26S proteasome proteolytic pathway in plants

Cross-references

Sequence databases
EMBL GenBank DDBJ	AP002047 Genomic DNA. Translation: BAB03143.1. Sequence problems. AC069474 Genomic DNA. Translation: AAG51006.1. Sequence problems. CP002686 Genomic DNA. Translation: AEE75186.1. BT001925 mRNA. Translation: AAN71924.1. AY086584 mRNA. Translation: AAM63646.1.
IPI	IPI00533688.
RefSeq	NP_566421.1. NM_112070.3.
UniGene	At.27112.
3D structure databases
ProteinModelPortal	Q84WW1.
SMR	Q84WW1. Positions 7-58.
ModBase	Search...
Protein-protein interaction databases
IntAct	Q84WW1. 3 interactions.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblPlants	AT3G12350.1; AT3G12350.1; AT3G12350.
GeneID	820413.
GenomeReviews	Gene locus AT3G12350 in contig BA000014_GR.
KEGG	ath:AT3G12350.
NMPDR	fig|3702.1.peg.13308.
Organism-specific databases
TAIR	At3g12350.
Phylogenomic databases
GeneTree	EPGT00050000018737.
HOGENOM	HBG589161.
InParanoid	Q84WW1.
OMA	QGLWKGI.
PhylomeDB	Q84WW1.
ProtClustDB	CLSN2688298.
Gene expression databases
ArrayExpress	Q84WW1.
Genevestigator	Q84WW1.
Family and domain databases
InterPro	IPR001810. F-box_dom_cyclin-like. IPR022364. F-box_dom_Skp2-like. [Graphical view]
SMART	SM00256. FBOX. 1 hit. [Graphical view]
SUPFAM	SSF81383. F-box_dom_Skp2-like. 1 hit.
PROSITE	PS50181. FBOX. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

FB140_ARATH

Accession

Primary (citable) accession number: Q84WW1
Secondary accession number(s): Q8LCI5, Q9C7A1, Q9LHH2

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 6, 2007
Last sequence update:	June 1, 2003
Last modified:	December 14, 2011
This is version 52 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Plant Protein Annotation Program