Reviewed, UniProtKB/Swiss-Prot Q84WW1 (FB140_ARATH)

Names and origin

Protein names

Recommended name:
    F-box protein At3g12350

Gene names

Ordered Locus Names:	At3g12350
ORF Names:	MQC3.17, T2E22.32

Organism

Arabidopsis thaliana (Mouse-ear cress) [Complete proteome]

Taxonomic identifier

3702 [NCBI]

Taxonomic lineage

Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › rosids › eurosids II › Brassicales › Brassicaceae › Arabidopsis

Protein attributes

Sequence length	422 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at protein level.

General annotation (Comments)

Sequence similarities	Contains 1 F-box domain.
Sequence caution	The sequence AAG51006.1 differs from that shown. Reason: Erroneous gene model prediction. The sequence BAB03143.1 differs from that shown. Reason: Erroneous gene model prediction. The predicted gene At3g12350 has been split into 2 genes: At3g12350 and At3g12360.

Ontologies

Keywords
Technical term	Complete proteome
Gene Ontology (GO)
Molecular function	protein binding Inferred from physical interaction. Source: IntAct
Complete GO annotation...

Binary interactions

With	Entry	#Exp.	IntAct	Notes
CAM1	P25854	1	EBI-1238751,EBI-1235664
CAM7	P59220	1	EBI-1238751,EBI-1236031
CML10	P30187	1	EBI-1238751,EBI-1238722

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 422	422	F-box protein At3g12350		PRO_0000274951
Regions
	Domain	5 – 52	48	F-box
Experimental info
	Sequence conflict	274	1	G → C in AAM63646. Ref.4
	Sequence conflict	284	1	I → M in AAM63646. Ref.4

Sequences

	Sequence		Length	Mass (Da)
	Q84WW1-1 [UniParc]. Last modified June 1, 2003. Version 1. Checksum: 13C8580242432D0A	FASTA	422	47,756
	10 20 30 40 50 60 MATFALPFCE IPEDLQLRIL SLLTPAEISS FACTSKRFAS LCQEDGKIWH VMCDQRWGKK 70 80 90 100 110 120 TKIQKWANGQ IPYRHLYKTL KGLENLIGFW RLCGRANPAA SSPPLVFFDW GSSFILGSRV 130 140 150 160 170 180 LSTGDDTYEV KKTPFLLMGI SPEGRSENFL DLVGGNLRSV DDDLKELEAS NNLVSVDVNF 190 200 210 220 230 240 MGNGHIMVEE NRCFTNNNRR EDQRSSGDES DDLISSPNFS EMYTQLANKT SPGGDRRRQK 250 260 270 280 290 300 RKEKERQASR TKWEPEHFLK VADCSPTPTR PLQGLWKGFC EGSIELYLVK YDEVGGIICR 310 320 330 340 350 360 KVEDLSLSRY TPPVFWTPKH TFIRSPFSAE EELLLNSRIH ISPFAEVHEN VVSGMLYMKS 370 380 390 400 410 420 SCDLVLPGEP GNGIGFLRGE GRVWLYDNGT FGFGFLRDQF IIDLKRVALE DGCLADEVEA CM

References

[1]	"Structural analysis of Arabidopsis thaliana chromosome 3. II. Sequence features of the 4,251,695 bp regions covered by 90 P1, TAC and BAC clones." Kaneko T., Katoh T., Sato S., Nakamura Y., Asamizu E., Tabata S. DNA Res. 7:217-221(2000) [PubMed: 10907853] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. Columbia.
[2]	"Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana." Salanoubat M., Lemcke K., Rieger M., Ansorge W., Unseld M., Fartmann B., Valle G., Bloecker H., Perez-Alonso M., Obermaier B., Delseny M., Boutry M., Grivell L.A., Mache R., Puigdomenech P., De Simone V., Choisne N., Artiguenave F. , Robert C., Brottier P., Wincker P., Cattolico L., Weissenbach J., Saurin W., Quetier F., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Benes V., Wurmbach E., Drzonek H., Erfle H., Jordan N., Bangert S., Wiedelmann R., Kranz H., Voss H., Holland R., Brandt P., Nyakatura G., Vezzi A., D'Angelo M., Pallavicini A., Toppo S., Simionati B., Conrad A., Hornischer K., Kauer G., Loehnert T.-H., Nordsiek G., Reichelt J., Scharfe M., Schoen O., Bargues M., Terol J., Climent J., Navarro P., Collado C., Perez-Perez A., Ottenwaelder B., Duchemin D., Cooke R., Laudie M., Berger-Llauro C., Purnelle B., Masuy D., de Haan M., Maarse A.C., Alcaraz J.-P., Cottet A., Casacuberta E., Monfort A., Argiriou A., Flores M., Liguori R., Vitale D., Mannhaupt G., Haase D., Schoof H., Rudd S., Zaccaria P., Mewes H.-W., Mayer K.F.X., Kaul S., Town C.D., Koo H.L., Tallon L.J., Jenkins J., Rooney T., Rizzo M., Walts A., Utterback T., Fujii C.Y., Shea T.P., Creasy T.H., Haas B., Maiti R., Wu D., Peterson J., Van Aken S., Pai G., Militscher J., Sellers P., Gill J.E., Feldblyum T.V., Preuss D., Lin X., Nierman W.C., Salzberg S.L., White O., Venter J.C., Fraser C.M., Kaneko T., Nakamura Y., Sato S., Kato T., Asamizu E., Sasamoto S., Kimura T., Idesawa K., Kawashima K., Kishida Y., Kiyokawa C., Kohara M., Matsumoto M., Matsuno A., Muraki A., Nakayama S., Nakazaki N., Shinpo S., Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S. Nature 408:820-822(2000) [PubMed: 11130713] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. Columbia.
[3]	"Empirical analysis of transcriptional activity in the Arabidopsis genome." Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G. , Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R. Science 302:842-846(2003) [PubMed: 14593172] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Strain: cv. Columbia.
[4]	"Full-length cDNA from Arabidopsis thaliana." Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B., Feldmann K.A. Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].

Web resources

PlantsUBQ

A functional genomics database for the ubiquitin/26S proteasome proteolytic pathway in plants

Cross-references

Sequence databases
EMBLGenBankDDBJ	AP002047 Genomic DNA. Translation: BAB03143.1. Sequence problems. AC069474 Genomic DNA. Translation: AAG51006.1. Sequence problems. BT001925 mRNA. Translation: AAN71924.1. AY086584 mRNA. Translation: AAM63646.1.
IPI	IPI00533688.
RefSeq	NP_566421.1.
UniGene	At.27112
3D structure databases
ModBase	Search...
Protein-protein interaction databases
IntAct	Q84WW1. 3 interactions.
Genome annotation databases
GeneID	820413.
GenomeReviews	Gene locus AT3G12350 in contig BA000014_GR.
KEGG	ath:AT3G12350.
NMPDR	fig|3702.1.peg.13308.
Organism-specific databases
TAIR	At3g12350.
Phylogenomic databases
OMA	Q84WW1. PLQGLWK.
Gene expression databases
ArrayExpress	Q84WW1.
Family and domain databases
InterPro	IPR001810. F-box. [Graphical view]
Pfam	PF00646. F-box. 1 hit. [Graphical view]
SMART	SM00256. FBOX. 1 hit. [Graphical view]
PROSITE	PS50181. FBOX. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

FB140_ARATH

Accession

Primary (citable) accession number: Q84WW1
Secondary accession number(s): Q8LCI5, Q9C7A1, Q9LHH2

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 6, 2007
Last sequence update:	June 1, 2003
Last modified:	June 16, 2009
This is version 36 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

PPAP (Plant Proteome Annotation Project)