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Protein

Serine carboxypeptidase-like 43

Gene

SCPL43

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

Probable carboxypeptidase.By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei178PROSITE-ProRule annotation1
Active sitei350PROSITE-ProRule annotation1
Active sitei407PROSITE-ProRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionCarboxypeptidase, Hydrolase, Protease

Enzyme and pathway databases

ReactomeiR-ATH-6798695. Neutrophil degranulation.

Protein family/group databases

ESTHERiarath-AT2G12480. Carboxypeptidase_S10.
MEROPSiS10.A33.

Names & Taxonomyi

Protein namesi
Recommended name:
Serine carboxypeptidase-like 43 (EC:3.4.16.-)
Gene namesi
Name:SCPL43
Ordered Locus Names:At2g12480
ORF Names:T27D6.5
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 2

Organism-specific databases

AraportiAT2G12480.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 23Sequence analysisAdd BLAST23
ChainiPRO_000027465824 – 442Serine carboxypeptidase-like 43Add BLAST419

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi86 ↔ 313By similarity
Glycosylationi137N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi246 ↔ 258Sequence analysis
Glycosylationi253N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi302N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi318N-linked (GlcNAc...) asparagineSequence analysis1

Keywords - PTMi

Disulfide bond, Glycoprotein

Proteomic databases

PaxDbiQ84W27.
PRIDEiQ84W27.

Expressioni

Tissue specificityi

Expression not detected.1 Publication

Gene expression databases

ExpressionAtlasiQ84W27. baseline and differential.
GenevisibleiQ84W27. AT.

Interactioni

Protein-protein interaction databases

STRINGi3702.AT2G12480.2.

Structurei

3D structure databases

ProteinModelPortaliQ84W27.
SMRiQ84W27.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the peptidase S10 family.Curated

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiKOG1282. Eukaryota.
COG2939. LUCA.
HOGENOMiHOG000198295.
InParanoidiQ84W27.
KOiK16297.
PhylomeDBiQ84W27.

Family and domain databases

Gene3Di3.40.50.1820. 1 hit.
InterProiView protein in InterPro
IPR029058. AB_hydrolase.
IPR001563. Peptidase_S10.
IPR018202. Ser_caboxypep_ser_AS.
PANTHERiPTHR11802. PTHR11802. 2 hits.
PfamiView protein in Pfam
PF00450. Peptidase_S10. 1 hit.
PRINTSiPR00724. CRBOXYPTASEC.
SUPFAMiSSF53474. SSF53474. 1 hit.
PROSITEiView protein in PROSITE
PS00131. CARBOXYPEPT_SER_SER. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

This entry describes 1 isoform i produced by alternative splicing. AlignAdd to basket

Note: A number of isoforms are produced. According to EST sequences.
Isoform 1 (identifier: Q84W27-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MVSSRAVVMA IMVLVTVQWL VFAEGYPEED LVARLPGQPN VGFRQFAGYV
60 70 80 90 100
DVDSENGRSL FYYYVEAVKE PDTKPLTLWL NGGPGCSSVG GGAFTELGPF
110 120 130 140 150
YPTGDGRGLR LNSMSWNKAS NLLFVESPAG VGWSYSNRSS DYNTGDKSTV
160 170 180 190 200
NDMLVFLLRW FNKFPELKSR DLFLTGESYA GHYIPQLADV ILSYNSRSSG
210 220 230 240 250
FKFNVKGIAI GNPLLKLDRD FAAAYEYFWS HGMISDEVRL TIMNQCDFAN
260 270 280 290 300
PKNMSNACIY AIVESSVLTE YINSYHILLD VCYPSIVQQE LRLKKMNALH
310 320 330 340 350
ANRTRLPYEW TMCSNRLNYS GIDGYIDMLP SLKRIIQNQT PVWIFSGDQD
360 370 380 390 400
SVIPLQSSRT LVRELAEDLN FKTTIPYGAW FHKEQVGGWV TEYGNLLTFA
410 420 430 440
TVRGAAHMVP YAEPSRALHM FSSFMNGRRL PNKPDLKSST DD
Length:442
Mass (Da):49,774
Last modified:June 1, 2003 - v1
Checksum:i787C9B71A2D50294
GO

Sequence cautioni

Q84W27: The sequence AAD28662 differs from that shown. Reason: Erroneous gene model prediction.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC007268 Genomic DNA. Translation: AAD28662.1. Sequence problems.
CP002685 Genomic DNA. Translation: AEC06202.1.
BT004306 mRNA. Translation: AAO42304.1.
PIRiD84503.
RefSeqiNP_001323740.1. NM_001335380.1.
NP_178937.2. NM_126893.4. [Q84W27-1]
UniGeneiAt.40719.

Genome annotation databases

EnsemblPlantsiAT2G12480.1; AT2G12480.1; AT2G12480. [Q84W27-1]
GeneIDi815721.
GrameneiAT2G12480.1; AT2G12480.1; AT2G12480.
KEGGiath:AT2G12480.

Keywords - Coding sequence diversityi

Alternative splicing

Similar proteinsi

Entry informationi

Entry nameiSCP43_ARATH
AccessioniPrimary (citable) accession number: Q84W27
Secondary accession number(s): Q9SHU3
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 6, 2007
Last sequence update: June 1, 2003
Last modified: October 25, 2017
This is version 87 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. Peptidase families
    Classification of peptidase families and list of entries
  3. SIMILARITY comments
    Index of protein domains and families