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Protein

Serine carboxypeptidase-like 43

Gene

SCPL43

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

Probable carboxypeptidase.By similarity

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei178 – 1781PROSITE-ProRule annotation
Active sitei350 – 3501PROSITE-ProRule annotation
Active sitei407 – 4071PROSITE-ProRule annotation

GO - Molecular functioni

  1. serine-type carboxypeptidase activity Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Carboxypeptidase, Hydrolase, Protease

Enzyme and pathway databases

BioCyciARA:AT2G12480-MONOMER.
ARA:GQT-2236-MONOMER.

Protein family/group databases

MEROPSiS10.A33.

Names & Taxonomyi

Protein namesi
Recommended name:
Serine carboxypeptidase-like 43 (EC:3.4.16.-)
Gene namesi
Name:SCPL43
Ordered Locus Names:At2g12480
ORF Names:T27D6.5
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
ProteomesiUP000006548 Componenti: Chromosome 2

Organism-specific databases

TAIRiAT2G12480.

Subcellular locationi

  1. Secreted Curated

GO - Cellular componenti

  1. extracellular region Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2323Sequence AnalysisAdd
BLAST
Chaini24 – 442419Serine carboxypeptidase-like 43PRO_0000274658Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Disulfide bondi86 ↔ 313By similarity
Glycosylationi137 – 1371N-linked (GlcNAc...)Sequence Analysis
Disulfide bondi246 ↔ 258Sequence Analysis
Glycosylationi253 – 2531N-linked (GlcNAc...)Sequence Analysis
Glycosylationi302 – 3021N-linked (GlcNAc...)Sequence Analysis
Glycosylationi318 – 3181N-linked (GlcNAc...)Sequence Analysis

Keywords - PTMi

Disulfide bond, Glycoprotein

Proteomic databases

PaxDbiQ84W27.
PRIDEiQ84W27.

Expressioni

Tissue specificityi

Expression not detected.1 Publication

Gene expression databases

ExpressionAtlasiQ84W27. baseline.
GenevestigatoriQ84W27.

Structurei

3D structure databases

ProteinModelPortaliQ84W27.
SMRiQ84W27. Positions 27-431.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the peptidase S10 family.Curated

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiCOG2939.
HOGENOMiHOG000198295.
InParanoidiQ84W27.
KOiK16297.
PhylomeDBiQ84W27.

Family and domain databases

Gene3Di3.40.50.1820. 1 hit.
InterProiIPR029058. AB_hydrolase.
IPR001563. Peptidase_S10.
IPR018202. Peptidase_S10_AS.
[Graphical view]
PANTHERiPTHR11802. PTHR11802. 1 hit.
PfamiPF00450. Peptidase_S10. 1 hit.
[Graphical view]
PRINTSiPR00724. CRBOXYPTASEC.
SUPFAMiSSF53474. SSF53474. 1 hit.
PROSITEiPS00131. CARBOXYPEPT_SER_SER. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

This entry describes 1 isoform i produced by alternative splicing. AlignAdd to basket

Note: A number of isoforms are produced. According to EST sequences.

Isoform 1 (identifier: Q84W27-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MVSSRAVVMA IMVLVTVQWL VFAEGYPEED LVARLPGQPN VGFRQFAGYV
60 70 80 90 100
DVDSENGRSL FYYYVEAVKE PDTKPLTLWL NGGPGCSSVG GGAFTELGPF
110 120 130 140 150
YPTGDGRGLR LNSMSWNKAS NLLFVESPAG VGWSYSNRSS DYNTGDKSTV
160 170 180 190 200
NDMLVFLLRW FNKFPELKSR DLFLTGESYA GHYIPQLADV ILSYNSRSSG
210 220 230 240 250
FKFNVKGIAI GNPLLKLDRD FAAAYEYFWS HGMISDEVRL TIMNQCDFAN
260 270 280 290 300
PKNMSNACIY AIVESSVLTE YINSYHILLD VCYPSIVQQE LRLKKMNALH
310 320 330 340 350
ANRTRLPYEW TMCSNRLNYS GIDGYIDMLP SLKRIIQNQT PVWIFSGDQD
360 370 380 390 400
SVIPLQSSRT LVRELAEDLN FKTTIPYGAW FHKEQVGGWV TEYGNLLTFA
410 420 430 440
TVRGAAHMVP YAEPSRALHM FSSFMNGRRL PNKPDLKSST DD
Length:442
Mass (Da):49,774
Last modified:June 1, 2003 - v1
Checksum:i787C9B71A2D50294
GO

Sequence cautioni

The sequence AAD28662.1 differs from that shown. Reason: Erroneous gene model prediction. Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC007268 Genomic DNA. Translation: AAD28662.1. Sequence problems.
CP002685 Genomic DNA. Translation: AEC06202.1.
BT004306 mRNA. Translation: AAO42304.1.
PIRiD84503.
RefSeqiNP_178937.2. NM_126893.4. [Q84W27-1]
UniGeneiAt.40719.

Genome annotation databases

EnsemblPlantsiAT2G12480.1; AT2G12480.1; AT2G12480. [Q84W27-1]
GeneIDi815721.
KEGGiath:AT2G12480.

Keywords - Coding sequence diversityi

Alternative splicing

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC007268 Genomic DNA. Translation: AAD28662.1. Sequence problems.
CP002685 Genomic DNA. Translation: AEC06202.1.
BT004306 mRNA. Translation: AAO42304.1.
PIRiD84503.
RefSeqiNP_178937.2. NM_126893.4. [Q84W27-1]
UniGeneiAt.40719.

3D structure databases

ProteinModelPortaliQ84W27.
SMRiQ84W27. Positions 27-431.
ModBaseiSearch...
MobiDBiSearch...

Protein family/group databases

MEROPSiS10.A33.

Proteomic databases

PaxDbiQ84W27.
PRIDEiQ84W27.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT2G12480.1; AT2G12480.1; AT2G12480. [Q84W27-1]
GeneIDi815721.
KEGGiath:AT2G12480.

Organism-specific databases

TAIRiAT2G12480.

Phylogenomic databases

eggNOGiCOG2939.
HOGENOMiHOG000198295.
InParanoidiQ84W27.
KOiK16297.
PhylomeDBiQ84W27.

Enzyme and pathway databases

BioCyciARA:AT2G12480-MONOMER.
ARA:GQT-2236-MONOMER.

Miscellaneous databases

PROiQ84W27.

Gene expression databases

ExpressionAtlasiQ84W27. baseline.
GenevestigatoriQ84W27.

Family and domain databases

Gene3Di3.40.50.1820. 1 hit.
InterProiIPR029058. AB_hydrolase.
IPR001563. Peptidase_S10.
IPR018202. Peptidase_S10_AS.
[Graphical view]
PANTHERiPTHR11802. PTHR11802. 1 hit.
PfamiPF00450. Peptidase_S10. 1 hit.
[Graphical view]
PRINTSiPR00724. CRBOXYPTASEC.
SUPFAMiSSF53474. SSF53474. 1 hit.
PROSITEiPS00131. CARBOXYPEPT_SER_SER. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Columbia.
  2. The Arabidopsis Information Resource (TAIR)
    Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
    Cited for: GENOME REANNOTATION.
    Strain: cv. Columbia.
  3. "Empirical analysis of transcriptional activity in the Arabidopsis genome."
    Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G.
    , Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R.
    Science 302:842-846(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: cv. Columbia.
  4. "An expression and bioinformatics analysis of the Arabidopsis serine carboxypeptidase-like gene family."
    Fraser C.M., Rider L.W., Chapple C.
    Plant Physiol. 138:1136-1148(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: GENE FAMILY, TISSUE SPECIFICITY, NOMENCLATURE.

Entry informationi

Entry nameiSCP43_ARATH
AccessioniPrimary (citable) accession number: Q84W27
Secondary accession number(s): Q9SHU3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 6, 2007
Last sequence update: June 1, 2003
Last modified: April 29, 2015
This is version 71 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. Peptidase families
    Classification of peptidase families and list of entries
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.