Reviewed, UniProtKB/Swiss-Prot Q84VY5 (DPNP4_ARATH)

Names and origin

Protein names

Recommended name:
    Probable SAL4 phosphatase
Alternative name(s):
    3'(2'),5'-bisphosphate nucleotidase 4
    EC=3.1.3.7
    3'(2'),5'-bisphosphonucleoside 3'(2')-phosphohydrolase 4
    DPNPase 4
    Inositol-1,4-bisphosphate 1-phosphatase 4
    EC=3.1.3.57
    Inositol polyphosphate 1-phosphatase 4
      Short name=IPPase 4

Gene names

Name:	SAL4
Ordered Locus Names:	At5g09290
ORF Names:	T5E8_90

Organism

Arabidopsis thaliana (Mouse-ear cress) [Complete proteome]

Taxonomic identifier

3702 [NCBI]

Taxonomic lineage

Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › rosids › eurosids II › Brassicales › Brassicaceae › Arabidopsis

Protein attributes

Sequence length	345 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Function	Converts adenosine 3'-phosphate 5'-phosphosulfate (PAPS) to adenosine 5'-phosphosulfate (APS) and 3'(2')-phosphoadenosine 5'- phosphate (PAP) to AMP By similarity. Is also able to hydrolyze inositol 1,4-bisphosphate By similarity.
Catalytic activity	Adenosine 3',5'-bisphosphate + H2O = adenosine 5'-phosphate + phosphate. 1D-myo-inositol 1,4-bisphosphate + H2O = 1D-myo-inositol 4-phosphate + phosphate.
Cofactor	Magnesium By similarity.
Pathway	Signal transduction; phosphatidylinositol signaling pathway.
Sequence similarities	Belongs to the inositol monophosphatase family.
Sequence caution	The sequence CAC05455.1 differs from that shown. Reason: Erroneous gene model prediction.

Ontologies

Keywords
Ligand	Magnesium Metal-binding
Molecular function	Hydrolase
Technical term	Complete proteome Multifunctional enzyme
Gene Ontology (GO)
Biological process	sulfur metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	3'(2'),5'-bisphosphate nucleotidase activity Inferred from electronic annotation. Source: EC inositol-1,4-bisphosphate 1-phosphatase activity Inferred from electronic annotation. Source: EC magnesium ion binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 345	345	Probable SAL4 phosphatase		PRO_0000142533
Sites
	Metal binding	71	1	Magnesium 1 By similarity
	Metal binding	134	1	Magnesium 1 By similarity
	Metal binding	134	1	Magnesium 2 By similarity
	Metal binding	136	1	Magnesium 1; via carbonyl oxygen By similarity
	Metal binding	137	1	Magnesium 2 By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q84VY5-1 [UniParc]. Last modified June 1, 2003. Version 1. Checksum: CD6CBD373A286706	FASTA	345	37,489
	10 20 30 40 50 60 MPYEKELAAA KKAVSLAARL SQEVQKSLLQ SDVRSKSDKS PVTAADYGSQ AVISHVLERE 70 80 90 100 110 120 LHPEPLYLVA EENAEDLHKN GAEEFLESIT KLVNNALASD DSYANSSLSM DDVRKAIDHG 130 140 150 160 170 180 RSQGGSSGRH WILDPVDGTR GFVKGEEYAV ALALLVEGKV VLGVMACPKL ENHKSSSSGC 190 200 210 220 230 240 LFFATVGEGA YVQSLEGDSH PPQKVQVSNI ENPEEATFVE SSHKPIPIHS SIANKLGIKA 250 260 270 280 290 300 PPLRIHSQVK YAALARGDAE IYLRFTLKGY REFIWNHAAG AIITTEAGGV VCDADGNPLD 310 320 330 340 FSRGNHLEHK TGIVVSTKNL MPRLLKAIRE SIEEEMLLSE TQLKL

References

[1]

"Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana." Tabata S., Kaneko T., Nakamura Y., Kotani H., Kato T., Asamizu E., Miyajima N., Sasamoto S., Kimura T., Hosouchi T., Kawashima K., Kohara M., Matsumoto M., Matsuno A., Muraki A., Nakayama S., Nakazaki N., Naruo K. , Okumura S., Shinpo S., Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Sato S., de la Bastide M., Huang E., Spiegel L., Gnoj L., O'Shaughnessy A., Preston R., Habermann K., Murray J., Johnson D., Rohlfing T., Nelson J., Stoneking T., Pepin K., Spieth J., Sekhon M., Armstrong J., Becker M., Belter E., Cordum H., Cordes M., Courtney L., Courtney W., Dante M., Du H., Edwards J., Fryman J., Haakensen B., Lamar E., Latreille P., Leonard S., Meyer R., Mulvaney E., Ozersky P., Riley A., Strowmatt C., Wagner-McPherson C., Wollam A., Yoakum M., Bell M., Dedhia N., Parnell L., Shah R., Rodriguez M., Hoon See L., Vil D., Baker J., Kirchoff K., Toth K., King L., Bahret A., Miller B., Marra M.A., Martienssen R., McCombie W.R., Wilson R.K., Murphy G., Bancroft I., Volckaert G., Wambutt R., Duesterhoeft A., Stiekema W., Pohl T., Entian K.-D., Terryn N., Hartley N., Bent E., Johnson S., Langham S.-A., McCullagh B., Robben J., Grymonprez B., Zimmermann W., Ramsperger U., Wedler H., Balke K., Wedler E., Peters S., van Staveren M., Dirkse W., Mooijman P., Klein Lankhorst R., Weitzenegger T., Bothe G., Rose M., Hauf J., Berneiser S., Hempel S., Feldpausch M., Lamberth S., Villarroel R., Gielen J., Ardiles W., Bents O., Lemcke K., Kolesov G., Mayer K.F.X., Rudd S., Schoof H., Schueller C., Zaccaria P., Mewes H.-W., Bevan M., Fransz P.F. Nature 408:823-826(2000) [PubMed: 11130714] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. Columbia.

[2]

"Empirical analysis of transcriptional activity in the Arabidopsis genome." Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G. , Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R. Science 302:842-846(2003) [PubMed: 14593172] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Strain: cv. Columbia.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AL391712 Genomic DNA. Translation: CAC05455.1. Sequence problems. BT004622 mRNA. Translation: AAO42868.1.
IPI	IPI00537138.
RefSeq	NP_196491.2.
UniGene	At.32535
3D structure databases
HSSP	HSSP built from PDB template 1KA1 based on UniProtKB P32179.
ModBase	Search...
Genome annotation databases
GeneID	830788.
GenomeReviews	Gene locus AT5G09290 in contig BA000015_GR.
KEGG	ath:AT5G09290.
NMPDR	fig|3702.1.peg.23048.
Organism-specific databases
TAIR	At5g09290.
Enzyme and pathway databases
BRENDA	3.1.3.57. 302. 3.1.3.7. 302.
Gene expression databases
ArrayExpress	Q84VY5.
GermOnline	AT5G09290. Arabidopsis thaliana.
Family and domain databases
InterPro	IPR006239. Bisphos_HAL2. IPR000760. Inositol_P. [Graphical view]
PANTHER	PTHR20854. Inositol_P. 1 hit.
Pfam	PF00459. Inositol_P. 1 hit. [Graphical view]
PRINTS	PR00378. INOSPHPHTASE.
TIGRFAMs	TIGR01330. bisphos_HAL2. 1 hit.
PROSITE	PS00629. IMP_1. 1 hit. PS00630. IMP_2. False negative. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

DPNP4_ARATH

Accession

Primary (citable) accession number: Q84VY5
Secondary accession number(s): Q9FY86

Entry history

Integrated into UniProtKB/Swiss-Prot:	August 29, 2003
Last sequence update:	June 1, 2003
Last modified:	June 16, 2009
This is version 49 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

PPAP (Plant Proteome Annotation Project)