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Q84VY5 (DPNP4_ARATH) Reviewed, UniProtKB/Swiss-Prot

Last modified November 16, 2011. Version 70. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Probable SAL4 phosphatase
Alternative name(s):
3'(2'),5'-bisphosphate nucleotidase 4
EC=3.1.3.7
3'(2'),5'-bisphosphonucleoside 3'(2')-phosphohydrolase 4
DPNPase 4
Inositol polyphosphate 1-phosphatase 4
Short name=IPPase 4
Inositol-1,4-bisphosphate 1-phosphatase 4
EC=3.1.3.57
Gene names
Name:SAL4
Ordered Locus Names:At5g09290
ORF Names:T5E8_90
OrganismArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifier3702 [NCBI]
Taxonomic lineageEukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › rosids › malvids › Brassicales › Brassicaceae › Camelineae › Arabidopsis

Protein attributes

Sequence length345 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

Converts adenosine 3'-phosphate 5'-phosphosulfate (PAPS) to adenosine 5'-phosphosulfate (APS) and 3'(2')-phosphoadenosine 5'- phosphate (PAP) to AMP By similarity. Is also able to hydrolyze inositol 1,4-bisphosphate By similarity.

Catalytic activity

Adenosine 3',5'-bisphosphate + H2O = adenosine 5'-phosphate + phosphate.

1D-myo-inositol 1,4-bisphosphate + H2O = 1D-myo-inositol 4-phosphate + phosphate.

Cofactor

Magnesium By similarity.

Pathway

Signal transduction; phosphatidylinositol signaling pathway.

Sequence similarities

Belongs to the inositol monophosphatase family.

Sequence caution

The sequence CAC05455.1 differs from that shown. Reason: Erroneous gene model prediction.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 345345Probable SAL4 phosphatase
PRO_0000142533

Regions

Region136 – 1394Substrate binding By similarity

Sites

Metal binding711Magnesium 1 By similarity
Metal binding1341Magnesium 1 By similarity
Metal binding1341Magnesium 2 By similarity
Metal binding1361Magnesium 1; via carbonyl oxygen By similarity
Metal binding1371Magnesium 2 By similarity
Binding site711Substrate By similarity

Sequences

Sequence LengthMass (Da)Tools
Q84VY5 [UniParc].

Last modified June 1, 2003. Version 1.
Checksum: CD6CBD373A286706

FASTA34537,489
        10         20         30         40         50         60 
MPYEKELAAA KKAVSLAARL SQEVQKSLLQ SDVRSKSDKS PVTAADYGSQ AVISHVLERE 

        70         80         90        100        110        120 
LHPEPLYLVA EENAEDLHKN GAEEFLESIT KLVNNALASD DSYANSSLSM DDVRKAIDHG 

       130        140        150        160        170        180 
RSQGGSSGRH WILDPVDGTR GFVKGEEYAV ALALLVEGKV VLGVMACPKL ENHKSSSSGC 

       190        200        210        220        230        240 
LFFATVGEGA YVQSLEGDSH PPQKVQVSNI ENPEEATFVE SSHKPIPIHS SIANKLGIKA 

       250        260        270        280        290        300 
PPLRIHSQVK YAALARGDAE IYLRFTLKGY REFIWNHAAG AIITTEAGGV VCDADGNPLD 

       310        320        330        340 
FSRGNHLEHK TGIVVSTKNL MPRLLKAIRE SIEEEMLLSE TQLKL

« Hide

References

« Hide 'large scale' references
[1]"Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana."
Tabata S., Kaneko T., Nakamura Y., Kotani H., Kato T., Asamizu E., Miyajima N., Sasamoto S., Kimura T., Hosouchi T., Kawashima K., Kohara M., Matsumoto M., Matsuno A., Muraki A., Nakayama S., Nakazaki N., Naruo K. expand/collapse author list , Okumura S., Shinpo S., Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Sato S., de la Bastide M., Huang E., Spiegel L., Gnoj L., O'Shaughnessy A., Preston R., Habermann K., Murray J., Johnson D., Rohlfing T., Nelson J., Stoneking T., Pepin K., Spieth J., Sekhon M., Armstrong J., Becker M., Belter E., Cordum H., Cordes M., Courtney L., Courtney W., Dante M., Du H., Edwards J., Fryman J., Haakensen B., Lamar E., Latreille P., Leonard S., Meyer R., Mulvaney E., Ozersky P., Riley A., Strowmatt C., Wagner-McPherson C., Wollam A., Yoakum M., Bell M., Dedhia N., Parnell L., Shah R., Rodriguez M., Hoon See L., Vil D., Baker J., Kirchoff K., Toth K., King L., Bahret A., Miller B., Marra M.A., Martienssen R., McCombie W.R., Wilson R.K., Murphy G., Bancroft I., Volckaert G., Wambutt R., Duesterhoeft A., Stiekema W., Pohl T., Entian K.-D., Terryn N., Hartley N., Bent E., Johnson S., Langham S.-A., McCullagh B., Robben J., Grymonprez B., Zimmermann W., Ramsperger U., Wedler H., Balke K., Wedler E., Peters S., van Staveren M., Dirkse W., Mooijman P., Klein Lankhorst R., Weitzenegger T., Bothe G., Rose M., Hauf J., Berneiser S., Hempel S., Feldpausch M., Lamberth S., Villarroel R., Gielen J., Ardiles W., Bents O., Lemcke K., Kolesov G., Mayer K.F.X., Rudd S., Schoof H., Schueller C., Zaccaria P., Mewes H.-W., Bevan M., Fransz P.F.
Nature 408:823-826(2000) [PubMed: 11130714] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Columbia.
[2]The Arabidopsis Information Resource (TAIR)
Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
Cited for: GENOME REANNOTATION.
Strain: cv. Columbia.
[3]"Empirical analysis of transcriptional activity in the Arabidopsis genome."
Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G. expand/collapse author list , Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R.
Science 302:842-846(2003) [PubMed: 14593172] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: cv. Columbia.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AL391712 Genomic DNA. Translation: CAC05455.1. Sequence problems.
CP002688 Genomic DNA. Translation: AED91370.1.
BT004622 mRNA. Translation: AAO42868.1.
IPIIPI00537138.
RefSeqNP_196491.2. NM_120965.5.
UniGeneAt.32534.
At.32535.

3D structure databases

ProteinModelPortalQ84VY5.
SMRQ84VY5. Positions 2-334.
ModBaseSearch...

Proteomic databases

PRIDEQ84VY5.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsAT5G09290.1; AT5G09290.1; AT5G09290.
GeneID830788.
GenomeReviewsGene locus AT5G09290 in contig BA000015_GR.
KEGGath:AT5G09290.
NMPDRfig|3702.1.peg.23048.

Organism-specific databases

TAIRAt5g09290.

Phylogenomic databases

GeneTreeEPGT00070000029602.
HOGENOMHBG599916.
InParanoidQ84VY5.
OMASEEDCEI.
PhylomeDBQ84VY5.
ProtClustDBCLSN2914821.

Gene expression databases

ArrayExpressQ84VY5.
GenevestigatorQ84VY5.
GermOnlineAT5G09290. Arabidopsis thaliana.

Family and domain databases

InterProIPR006239. Bisphos_HAL2.
IPR020583. Inositol_monoP_metal-BS.
IPR000760. Inositol_monophosphatase.
[Graphical view]
KOK15422.
PANTHERPTHR20854. Inositol_P. 1 hit.
PfamPF00459. Inositol_P. 1 hit.
[Graphical view]
TIGRFAMsTIGR01330. Bisphos_HAL2. 1 hit.
PROSITEPS00629. IMP_1. 1 hit.
PS00630. IMP_2. False negative.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameDPNP4_ARATH
AccessionPrimary (citable) accession number: Q84VY5
Secondary accession number(s): Q9FY86
Entry history
Integrated into UniProtKB/Swiss-Prot: August 29, 2003
Last sequence update: June 1, 2003
Last modified: November 16, 2011
This is version 70 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

Arabidopsis thaliana

Arabidopsis thaliana: entries and gene names

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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