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Q84V36

- POLC3_CHEAL

UniProt

Q84V36 - POLC3_CHEAL

Protein

Polcalcin Che a 3

Gene
N/A
Organism
Chenopodium album (Lamb's-quarters)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli
  1. Functioni

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Calcium bindingi21 – 32121PROSITE-ProRule annotationAdd
    BLAST
    Calcium bindingi56 – 67122PROSITE-ProRule annotationAdd
    BLAST

    GO - Molecular functioni

    1. calcium ion binding Source: InterPro

    Keywords - Ligandi

    Calcium, Metal-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Polcalcin Che a 3
    Alternative name(s):
    Calcium-binding pollen allergen Che a 3
    Allergen: Che a 3
    OrganismiChenopodium album (Lamb's-quarters)
    Taxonomic identifieri3559 [NCBI]
    Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaeCaryophyllalesAmaranthaceaeChenopodioideaeAtripliceaeChenopodium

    Pathology & Biotechi

    Allergenic propertiesi

    Causes an allergic reaction in human. Binds to IgE.1 Publication

    Keywords - Diseasei

    Allergen

    Protein family/group databases

    Allergomei1069. Che a 3.
    3190. Che a 3.0101.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 8686Polcalcin Che a 3PRO_0000073671Add
    BLAST

    Structurei

    Secondary structure

    1
    86
    Legend: HelixTurnBeta strand
    Show more details
    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Helixi7 – 2014
    Beta strandi25 – 295
    Helixi30 – 389
    Turni39 – 424
    Helixi45 – 5511
    Beta strandi60 – 634
    Helixi65 – 7410
    Turni76 – 783
    Helixi79 – 857

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    EntryMethodResolution (Å)ChainPositionsPDBsum
    2OPOX-ray1.75A/B/C/D1-86[»]
    ProteinModelPortaliQ84V36.
    SMRiQ84V36. Positions 2-86.
    ModBaseiSearch...
    MobiDBiSearch...

    Miscellaneous databases

    EvolutionaryTraceiQ84V36.

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini8 – 4336EF-hand 1PROSITE-ProRule annotationAdd
    BLAST
    Domaini43 – 7836EF-hand 2PROSITE-ProRule annotationAdd
    BLAST

    Sequence similaritiesi

    Contains 2 EF-hand domains.PROSITE-ProRule annotation

    Keywords - Domaini

    Repeat

    Family and domain databases

    Gene3Di1.10.238.10. 1 hit.
    InterProiIPR011992. EF-hand-dom_pair.
    IPR018247. EF_Hand_1_Ca_BS.
    IPR002048. EF_hand_dom.
    [Graphical view]
    PfamiPF13499. EF-hand_7. 1 hit.
    [Graphical view]
    SMARTiSM00054. EFh. 2 hits.
    [Graphical view]
    PROSITEiPS00018. EF_HAND_1. 2 hits.
    PS50222. EF_HAND_2. 2 hits.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q84V36-1 [UniParc]FASTAAdd to Basket

    « Hide

    MAAEDTPQDI ADRERIFKRF DTNGDGKISS SELGDALKTL GSVTPDEVRR   50
    MMAEIDTDGD GFISFDEFTD FARANRGLVK DVSKIF 86
    Length:86
    Mass (Da):9,552
    Last modified:June 1, 2003 - v1
    Checksum:iD950CE65546181BB
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AY082338 mRNA. Translation: AAL92871.1.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AY082338 mRNA. Translation: AAL92871.1 .

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    Entry Method Resolution (Å) Chain Positions PDBsum
    2OPO X-ray 1.75 A/B/C/D 1-86 [» ]
    ProteinModelPortali Q84V36.
    SMRi Q84V36. Positions 2-86.
    ModBasei Search...
    MobiDBi Search...

    Protein family/group databases

    Allergomei 1069. Che a 3.
    3190. Che a 3.0101.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Miscellaneous databases

    EvolutionaryTracei Q84V36.

    Family and domain databases

    Gene3Di 1.10.238.10. 1 hit.
    InterProi IPR011992. EF-hand-dom_pair.
    IPR018247. EF_Hand_1_Ca_BS.
    IPR002048. EF_hand_dom.
    [Graphical view ]
    Pfami PF13499. EF-hand_7. 1 hit.
    [Graphical view ]
    SMARTi SM00054. EFh. 2 hits.
    [Graphical view ]
    PROSITEi PS00018. EF_HAND_1. 2 hits.
    PS50222. EF_HAND_2. 2 hits.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Profilin (Che a 2) and polcalcin (Che a 3) are relevant allergens of Chenopodium album pollen: isolation, amino acid sequences, and immunologic properties."
      Barderas R., Villalba M., Pascual C.Y., Batanero E., Rodriguez R.
      J. Allergy Clin. Immunol. 113:1192-1198(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA], ALLERGEN.
      Tissue: Pollen.

    Entry informationi

    Entry nameiPOLC3_CHEAL
    AccessioniPrimary (citable) accession number: Q84V36
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: May 24, 2004
    Last sequence update: June 1, 2003
    Last modified: October 1, 2014
    This is version 52 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programPlant Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    3D-structure

    Documents

    1. Allergens
      Nomenclature of allergens and list of entries
    2. PDB cross-references
      Index of Protein Data Bank (PDB) cross-references
    3. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3