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Q84V36 (POLC3_CHEAL) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 51. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Polcalcin Che a 3
Alternative name(s):
Calcium-binding pollen allergen Che a 3
Allergen=Che a 3
OrganismChenopodium album (Lamb's-quarters)
Taxonomic identifier3559 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaeCaryophyllalesAmaranthaceaeChenopodioideaeAtripliceaeChenopodium

Protein attributes

Sequence length86 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Allergenic properties

Causes an allergic reaction in human. Binds to IgE. Ref.1

Sequence similarities

Contains 2 EF-hand domains.

Ontologies

Keywords
   DiseaseAllergen
   DomainRepeat
   LigandCalcium
Metal-binding
   Technical term3D-structure
Gene Ontology (GO)
   Molecular_functioncalcium ion binding

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 8686Polcalcin Che a 3
PRO_0000073671

Regions

Domain8 – 4336EF-hand 1
Domain43 – 7836EF-hand 2
Calcium binding21 – 32121 Potential
Calcium binding56 – 67122 Potential

Secondary structure

................ 86
Helix Strand Turn

Details...

Sequences

Sequence LengthMass (Da)Tools
Q84V36 [UniParc].

Last modified June 1, 2003. Version 1.
Checksum: D950CE65546181BB

FASTA869,552
        10         20         30         40         50         60 
MAAEDTPQDI ADRERIFKRF DTNGDGKISS SELGDALKTL GSVTPDEVRR MMAEIDTDGD 

        70         80 
GFISFDEFTD FARANRGLVK DVSKIF 

« Hide

References

[1]"Profilin (Che a 2) and polcalcin (Che a 3) are relevant allergens of Chenopodium album pollen: isolation, amino acid sequences, and immunologic properties."
Barderas R., Villalba M., Pascual C.Y., Batanero E., Rodriguez R.
J. Allergy Clin. Immunol. 113:1192-1198(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA], ALLERGEN.
Tissue: Pollen.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AY082338 mRNA. Translation: AAL92871.1.

3D structure databases

PDBe
RCSB-PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
2OPOX-ray1.75A/B/C/D1-86[»]
ProteinModelPortalQ84V36.
SMRQ84V36. Positions 2-86.
ModBaseSearch...
MobiDBSearch...

Protein family/group databases

Allergome1069. Che a 3.
3190. Che a 3.0101.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

Gene3D1.10.238.10. 1 hit.
InterProIPR011992. EF-hand-dom_pair.
IPR018247. EF_Hand_1_Ca_BS.
IPR002048. EF_hand_dom.
[Graphical view]
PfamPF13499. EF-hand_7. 1 hit.
[Graphical view]
SMARTSM00054. EFh. 2 hits.
[Graphical view]
PROSITEPS00018. EF_HAND_1. 2 hits.
PS50222. EF_HAND_2. 2 hits.
[Graphical view]
ProtoNetSearch...

Other

EvolutionaryTraceQ84V36.

Entry information

Entry namePOLC3_CHEAL
AccessionPrimary (citable) accession number: Q84V36
Entry history
Integrated into UniProtKB/Swiss-Prot: May 24, 2004
Last sequence update: June 1, 2003
Last modified: February 19, 2014
This is version 51 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PDB cross-references

Index of Protein Data Bank (PDB) cross-references

Allergens

Nomenclature of allergens and list of entries