Q84SN3 (CDKF3_ORYSJ) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Cyclin-dependent kinase F-3
Short name=CDKF;3
EC=2.7.11.22
EC=2.7.11.23

Alternative name(s):
Serine/threonine-protein kinase MHK-like protein 1

Gene names

Name:	CDKF-3
Ordered Locus Names:	Os03g0847600, LOC_Os03g63020
ORF Names:	OSJNBb0043P23.8

Organism

Oryza sativa subsp. japonica (Rice) [Reference proteome]

Taxonomic identifier

39947 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Viridiplantae › Streptophyta › Streptophytina › Embryophyta › Tracheophyta › Euphyllophyta › Spermatophyta › Magnoliophyta › Liliopsida › commelinids › Poales › Poaceae › BEP clade › Ehrhartoideae › Oryzeae › Oryza › Oryza sativa

Protein attributes

Sequence length	433 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Catalytic activity	ATP + a protein = ADP + a phosphoprotein. ATP + [DNA-directed RNA polymerase] = ADP + [DNA-directed RNA polymerase] phosphate.
Induction	Down-regulated by cytokinin. Ref.5
Sequence similarities	Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily. Contains 1 protein kinase domain.

Ontologies

Keywords
Ligand	ATP-binding Nucleotide-binding
Molecular function	Kinase Serine/threonine-protein kinase Transferase
PTM	Phosphoprotein
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	cell cycle Inferred from electronic annotation. Source: GOC
Molecular_function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW RNA polymerase II carboxy-terminal domain kinase activity Inferred from electronic annotation. Source: EC cyclin-dependent protein serine/threonine kinase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 433	433	Cyclin-dependent kinase F-3		PRO_0000296108
Regions
	Domain	4 – 283	280	Protein kinase
	Nucleotide binding	10 – 18	9	ATP By similarity
Sites
	Active site	125	1	Proton acceptor By similarity
	Binding site	33	1	ATP By similarity
Amino acid modifications
	Modified residue	151	1	Phosphoserine By similarity
	Modified residue	156	1	Phosphothreonine By similarity
Experimental info
	Sequence conflict	120	1	G → S in AK066947. Ref.4

Sequences

	Sequence		Length	Mass (Da)
	Q84SN3 [UniParc]. Last modified June 1, 2003. Version 1. Checksum: 28AC98AE930BDE89	FASTA	433	49,515
	10 20 30 40 50 60 MERYKVIREI GDGTCGNVFR AYNTETNEIV AVKKMKRKFF QWEECISLRE VKALQKLNHP 70 80 90 100 110 120 NIVKLKEVTM ENHELFFIFE NMECNLYDVI RERQAAFSEE EIRNFMVQIL QGLAYMHNNG 130 140 150 160 170 180 YFHRDLKPEN LLVTDGTVKI ADFGLAREVS SSPPYTDYVS TRWYRAPEVL LQSSAYTPAI 190 200 210 220 230 240 DMWAVGAILA ELFTLSPLFP GGSETDQLYK ICAVLGTPDH TVWPEGMNLP RSSSFNFFQI 250 260 270 280 290 300 PPRNLWELIP NATLEAIDLI QQLCSWDPRR RPTAEQSLQH PFFNVGNWVP RPLHASHTKT 310 320 330 340 350 360 IETRPNPRLE LNLWDFGTEP EDNYLDLTLS LKPSFPGTDF SNNVPEHTKE EILLYPGFEN 370 380 390 400 410 420 PPVQSGFWPL VASDRPMGDV PAMSSWPQAY VVDGQATLPA VGFSGSPFGL SPLQPNLFEN 430 RSFATPIRQV NFF

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Sequence, annotation, and analysis of synteny between rice chromosome 3 and diverged grass species." The rice chromosome 3 sequencing consortium Buell C.R., Yuan Q., Ouyang S., Liu J., Zhu W., Wang A., Maiti R., Haas B., Wortman J., Pertea M., Jones K.M., Kim M., Overton L., Tsitrin T., Fadrosh D., Bera J., Weaver B., Jin S. , Johri S., Reardon M., Webb K., Hill J., Moffat K., Tallon L., Van Aken S., Lewis M., Utterback T., Feldblyum T., Zismann V., Iobst S., Hsiao J., de Vazeille A.R., Salzberg S.L., White O., Fraser C.M., Yu Y., Kim H., Rambo T., Currie J., Collura K., Kernodle-Thompson S., Wei F., Kudrna K., Ammiraju J.S.S., Luo M., Goicoechea J.L., Wing R.A., Henry D., Oates R., Palmer M., Pries G., Saski C., Simmons J., Soderlund C., Nelson W., de la Bastide M., Spiegel L., Nascimento L., Huang E., Preston R., Zutavern T., Palmer L., O'Shaughnessy A., Dike S., McCombie W.R., Minx P., Cordum H., Wilson R., Jin W., Lee H.R., Jiang J., Jackson S. Genome Res. 15:1284-1291(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. Nipponbare.
[2]	"The map-based sequence of the rice genome." International rice genome sequencing project (IRGSP) Nature 436:793-800(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. Nipponbare.
[3]	"The rice annotation project database (RAP-DB): 2008 update." The rice annotation project (RAP) Nucleic Acids Res. 36:D1028-D1033(2008) [PubMed] [Europe PMC] [Abstract] Cited for: GENOME REANNOTATION. Strain: cv. Nipponbare.
[4]	"Collection, mapping, and annotation of over 28,000 cDNA clones from japonica rice." The rice full-length cDNA consortium Science 301:376-379(2003) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Strain: cv. Nipponbare.
[5]	"Genome-wide identification and expression analysis of rice cell cycle genes." Guo J., Song J., Wang F., Zhang X.S. Plant Mol. Biol. 64:349-360(2007) [PubMed] [Europe PMC] [Abstract] Cited for: INDUCTION, GENE FAMILY.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AC099324 Genomic DNA. Translation: AAO73290.1. DP000009 Genomic DNA. Translation: ABF99883.1. AP008209 Genomic DNA. Translation: BAF13800.1. AK066947 mRNA. No translation available.
RefSeq	NP_001051886.1. NM_001058421.1.
UniGene	Os.8119.
3D structure databases
HSSP	HSSP built from PDB template 2BAJ based on UniProtKB Q16539.
ProteinModelPortal	Q84SN3.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblPlants	LOC_Os03g63020.2; LOC_Os03g63020.2; LOC_Os03g63020. LOC_Os03g63020.3; LOC_Os03g63020.3; LOC_Os03g63020. LOC_Os03g63020.5; LOC_Os03g63020.5; LOC_Os03g63020.
GeneID	4334774.
KEGG	osa:4334774.
Organism-specific databases
Gramene	Q84SN3.
Phylogenomic databases
eggNOG	COG0515.
ProtClustDB	CLSN2685794.
Gene expression databases
ArrayExpress	Q84SN3.
Family and domain databases
InterPro	IPR011009. Kinase-like_dom. IPR000719. Prot_kinase_cat_dom. IPR002290. Ser/Thr_dual-sp_kinase_dom. IPR008271. Ser/Thr_kinase_AS. [Graphical view]
Pfam	PF00069. Pkinase. 1 hit. [Graphical view]
SMART	SM00220. S_TKc. 1 hit. [Graphical view]
SUPFAM	SSF56112. Kinase_like. 1 hit.
PROSITE	PS00107. PROTEIN_KINASE_ATP. False negative. PS50011. PROTEIN_KINASE_DOM. 1 hit. PS00108. PROTEIN_KINASE_ST. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

CDKF3_ORYSJ

Accession

Primary (citable) accession number: Q84SN3

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 24, 2007
Last sequence update:	June 1, 2003
Last modified:	May 1, 2013
This is version 78 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Plant Protein Annotation Program