SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q84M93

- MPK17_ARATH

UniProt

Q84M93 - MPK17_ARATH

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Mitogen-activated protein kinase 17
Gene
MPK17, At2g01450, F2I9.7
Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed - Annotation score: 4 out of 5 - Experimental evidence at transcript leveli

Functioni

Catalytic activityi

ATP + a protein = ADP + a phosphoprotein.

Enzyme regulationi

Activated by threonine and tyrosine phosphorylation By similarity.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei45 – 451ATP By similarity
Active sitei142 – 1421Proton acceptor By similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi22 – 309ATP By similarity

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. MAP kinase activity Source: TAIR
  3. protein serine/threonine kinase activity Source: TAIR

GO - Biological processi

  1. MAPK cascade Source: GOC
  2. protein autophosphorylation Source: TAIR
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Serine/threonine-protein kinase, Transferase

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciARA:AT2G01450-MONOMER.
ARA:GQT-1826-MONOMER.
ARA:GQT-1827-MONOMER.
ARA:GQT-1828-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Mitogen-activated protein kinase 17 (EC:2.7.11.24)
Short name:
AtMPK17
Short name:
MAP kinase 17
Gene namesi
Name:MPK17
Ordered Locus Names:At2g01450
ORF Names:F2I9.7
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
ProteomesiUP000006548: Chromosome 2

Organism-specific databases

TAIRiAT2G01450.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 486486Mitogen-activated protein kinase 17
PRO_0000245817Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei178 – 1781Phosphothreonine By similarity
Modified residuei180 – 1801Phosphotyrosine By similarity
Modified residuei183 – 1831Phosphothreonine By similarity

Post-translational modificationi

Dually phosphorylated on Thr-178 and Tyr-180, which activates the enzyme By similarity.

Keywords - PTMi

Phosphoprotein

Proteomic databases

PRIDEiQ84M93.

Expressioni

Gene expression databases

ArrayExpressiQ84M93.
GenevestigatoriQ84M93.

Interactioni

Protein-protein interaction databases

IntActiQ84M93. 2 interactions.

Structurei

3D structure databases

ProteinModelPortaliQ84M93.
SMRiQ84M93. Positions 15-353.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini16 – 307292Protein kinase
Add
BLAST

Motif

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Motifi178 – 1803TXY

Domaini

The TXY motif contains the threonine and tyrosine residues whose phosphorylation activates the MAP kinases.

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0515.
HOGENOMiHOG000233024.
InParanoidiQ84M93.
KOiK00924.
OMAiADANKTH.
PhylomeDBiQ84M93.

Family and domain databases

InterProiIPR011009. Kinase-like_dom.
IPR003527. MAP_kinase_CS.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR002290. Ser/Thr_dual-sp_kinase_dom.
[Graphical view]
PfamiPF00069. Pkinase. 1 hit.
[Graphical view]
SMARTiSM00220. S_TKc. 1 hit.
[Graphical view]
SUPFAMiSSF56112. SSF56112. 1 hit.
PROSITEiPS01351. MAPK. 1 hit.
PS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q84M93-1 [UniParc]FASTAAdd to Basket

« Hide

MLEKEFFTEY GEASQYQIQE VVGKGSYGVV ASAECPHTGG KVAIKKMTNV    50
FEHVSDAIRI LREIKLLRLL RHPDIVEIKH IMLPPCRKEF KDIYVVFELM 100
ESDLHHVLKV NDDLTPQHHQ FFLYQLLRGL KFMHSAHVFH RDLKPKNILA 150
NADCKIKICD LGLARVSFTD SPSAVFWTDY VATRWYRAPE LCGSFYSNYT 200
PAIDMWSVGC IFAEMLTGKP LFPGKNVVHQ LELVTDLLGT PSPITLSRIR 250
NEKARKYLGN MRRKDPVPFT HKFPNIDPVA LKLLQRLIAF DPKDRPSAEE 300
ALADPYFQGL ANVDYEPSRQ PISKLEFEFE RRKLTRDDVR ELMYREILEY 350
HPQMLQEYLQ GEENINSHFL YPSGVDQFKQ EFARLEEHND DEEEHNSPPH 400
QRKYTSLPRE RVCSSEDEGS DSVHAQSSSA SVVFTPPQTP NTATGLSSQK 450
ASQVDKAATP VKRSACLMRS DSICASRCVG VSSAVS 486
Length:486
Mass (Da):55,493
Last modified:June 1, 2003 - v1
Checksum:i2741BC52DC3FFCE6
GO

Sequence cautioni

The sequence AAC67338.1 differs from that shown. Reason: Erroneous gene model prediction.

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC005560 Genomic DNA. Translation: AAC67338.1. Sequence problems.
CP002685 Genomic DNA. Translation: AEC05452.1.
CP002685 Genomic DNA. Translation: AEC05453.1.
CP002685 Genomic DNA. Translation: AEC05454.1.
CP002685 Genomic DNA. Translation: AEC05455.1.
BT006469 mRNA. Translation: AAP21277.1.
PIRiH84424.
RefSeqiNP_001030939.1. NM_001035862.2.
NP_001030940.1. NM_001035863.1.
NP_001030941.1. NM_001035864.1.
NP_178254.2. NM_126206.3.
UniGeneiAt.20212.

Genome annotation databases

EnsemblPlantsiAT2G01450.1; AT2G01450.1; AT2G01450.
AT2G01450.2; AT2G01450.2; AT2G01450.
AT2G01450.3; AT2G01450.3; AT2G01450.
AT2G01450.4; AT2G01450.4; AT2G01450.
GeneIDi814673.
KEGGiath:AT2G01450.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC005560 Genomic DNA. Translation: AAC67338.1 . Sequence problems.
CP002685 Genomic DNA. Translation: AEC05452.1 .
CP002685 Genomic DNA. Translation: AEC05453.1 .
CP002685 Genomic DNA. Translation: AEC05454.1 .
CP002685 Genomic DNA. Translation: AEC05455.1 .
BT006469 mRNA. Translation: AAP21277.1 .
PIRi H84424.
RefSeqi NP_001030939.1. NM_001035862.2.
NP_001030940.1. NM_001035863.1.
NP_001030941.1. NM_001035864.1.
NP_178254.2. NM_126206.3.
UniGenei At.20212.

3D structure databases

ProteinModelPortali Q84M93.
SMRi Q84M93. Positions 15-353.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

IntActi Q84M93. 2 interactions.

Proteomic databases

PRIDEi Q84M93.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblPlantsi AT2G01450.1 ; AT2G01450.1 ; AT2G01450 .
AT2G01450.2 ; AT2G01450.2 ; AT2G01450 .
AT2G01450.3 ; AT2G01450.3 ; AT2G01450 .
AT2G01450.4 ; AT2G01450.4 ; AT2G01450 .
GeneIDi 814673.
KEGGi ath:AT2G01450.

Organism-specific databases

GeneFarmi 870. 89.
TAIRi AT2G01450.

Phylogenomic databases

eggNOGi COG0515.
HOGENOMi HOG000233024.
InParanoidi Q84M93.
KOi K00924.
OMAi ADANKTH.
PhylomeDBi Q84M93.

Enzyme and pathway databases

BioCyci ARA:AT2G01450-MONOMER.
ARA:GQT-1826-MONOMER.
ARA:GQT-1827-MONOMER.
ARA:GQT-1828-MONOMER.

Gene expression databases

ArrayExpressi Q84M93.
Genevestigatori Q84M93.

Family and domain databases

InterProi IPR011009. Kinase-like_dom.
IPR003527. MAP_kinase_CS.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR002290. Ser/Thr_dual-sp_kinase_dom.
[Graphical view ]
Pfami PF00069. Pkinase. 1 hit.
[Graphical view ]
SMARTi SM00220. S_TKc. 1 hit.
[Graphical view ]
SUPFAMi SSF56112. SSF56112. 1 hit.
PROSITEi PS01351. MAPK. 1 hit.
PS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Columbia.
  2. The Arabidopsis Information Resource (TAIR)
    Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
    Cited for: GENOME REANNOTATION.
    Strain: cv. Columbia.
  3. "Empirical analysis of transcriptional activity in the Arabidopsis genome."
    Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G.
    , Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R.
    Science 302:842-846(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: cv. Columbia.
  4. "Mitogen-activated protein kinase cascades in plants: a new nomenclature."
    MAPK group
    Trends Plant Sci. 7:301-308(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: GENE FAMILY, NOMENCLATURE.
  5. Cited for: GENE FAMILY.

Entry informationi

Entry nameiMPK17_ARATH
AccessioniPrimary (citable) accession number: Q84M93
Secondary accession number(s): Q9ZVF9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 11, 2006
Last sequence update: June 1, 2003
Last modified: June 11, 2014
This is version 95 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi