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Q84M43 (CESA2_ORYSJ) Reviewed, UniProtKB/Swiss-Prot

Last modified December 14, 2011. Version 70. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
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to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable cellulose synthase A catalytic subunit 2 [UDP-forming]
EC=2.4.1.12
Alternative name(s):
OsCesA2
Gene names
Name:CESA2
Ordered Locus Names:Os03g0808100, LOC_Os03g59340
ORF Names:OSJNBa0059E14.5, OSJNBa0060M17.2, OsJ_012480
OrganismOryza sativa subsp. japonica (Rice)
Taxonomic identifier39947 [NCBI]
Taxonomic lineageEukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › Liliopsida › Poales › Poaceae › BEP clade › Ehrhartoideae › Oryzeae › Oryza

Protein attributes

Sequence length1073 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

Probable catalytic subunit of cellulose synthase terminal complexes ('rosettes'), required for beta-1,4-glucan microfibril crystallization, a major mechanism of the cell wall formation By similarity.

Catalytic activity

UDP-glucose + (1,4-beta-D-glucosyl)(n) = UDP + (1,4-beta-D-glucosyl)(n+1).

Cofactor

Binds 2 zinc ions per subunit By similarity.

Pathway

Glycan metabolism; plant cellulose biosynthesis.

Subcellular location

Cell membrane; Multi-pass membrane protein Probable.

Sequence similarities

Belongs to the glycosyltransferase 2 family. Plant cellulose synthase subfamily.

Contains 1 RING-type zinc finger.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 10731073Probable cellulose synthase A catalytic subunit 2 [UDP-forming]
PRO_0000319360

Regions

Topological domain1 – 270270Cytoplasmic Potential
Transmembrane271 – 29121Helical; Potential
Topological domain292 – 2932Extracellular Potential
Transmembrane294 – 31421Helical; Potential
Topological domain315 – 856542Cytoplasmic Potential
Transmembrane857 – 87721Helical; Potential
Topological domain878 – 8825Extracellular Potential
Transmembrane883 – 90321Helical; Potential
Topological domain904 – 91815Cytoplasmic Potential
Transmembrane919 – 93921Helical; Potential
Topological domain940 – 96930Extracellular Potential
Transmembrane970 – 99021Helical; Potential
Topological domain991 – 100111Cytoplasmic Potential
Transmembrane1002 – 102221Helical; Potential
Topological domain1023 – 10319Extracellular Potential
Transmembrane1032 – 105221Helical; Potential
Topological domain1053 – 107321Cytoplasmic Potential
Zinc finger13 – 5947RING-type; degenerate
Coiled coil443 – 47028 Potential

Sites

Active site3891 Potential
Active site7731 Potential
Metal binding131Zinc 1 By similarity
Metal binding161Zinc 1 By similarity
Metal binding321Zinc 2 By similarity
Metal binding351Zinc 2 By similarity
Metal binding401Zinc 1 By similarity
Metal binding431Zinc 1 By similarity
Metal binding551Zinc 2 By similarity
Metal binding581Zinc 2 By similarity
Binding site5551Substrate Potential
Binding site5571Substrate Potential

Experimental info

Sequence conflict2111K → E in AK069196. Ref.5

Sequences

Sequence LengthMass (Da)Tools
Q84M43 [UniParc].

Last modified June 1, 2003. Version 1.
Checksum: 55B677033E77A7BE

FASTA1,073120,682
        10         20         30         40         50         60 
MDGAKSGKQC HVCQICGDGV GTAADGELFT ACDVCGFPVC RPCYEYERKD GSQACPQCKT 

        70         80         90        100        110        120 
KYKRHKGSPP ILGDESDDVD ADDASDVNYP TSGNQDHKHK IAERMLTWRM NSGRNDDIVH 

       130        140        150        160        170        180 
SKYDSGEIGH PKYDSGEIPR IYIPSLTHSQ ISGEIPGASP DHMMSPVGNI GRRGHPFPYV 

       190        200        210        220        230        240 
NHSPNPSREF SGSLGNVAWK ERVDGWKMKD KGAIPMANGT SIAPSEGRGV GDIDASTDYN 

       250        260        270        280        290        300 
MEDALLNDET RQPLSRKVPI SSSRINPYRM VIVLRLIVLC IFLHYRITNP VRNAYPLWLL 

       310        320        330        340        350        360 
SVICEIWFAL SWILDQFPKW SPINRETYLD RLALRYDREG EPSQLAPVDI FVSTVDPMKE 

       370        380        390        400        410        420 
PPLVTANTVL SILAVDYPVD KVSCYVSDDG AAMLTFDALA ETSEFARKWV PFCKKYSIEP 

       430        440        450        460        470        480 
RAPEWYFAQK IDYLKDKVQA SFVKDRRAMK REYEEFKVRV NALVAKAQKV PEEGWIMQDG 

       490        500        510        520        530        540 
TPWPGNNTRD HPGMIQVFLG HSGGLDTEGN ELPRLVYVSR EKRPGFQHHK KAGAMNALVR 

       550        560        570        580        590        600 
VSAVLTNGQY LLNLDCDHYI NNSKALREAM CFLMDPNLGR RVCYVQFPQR FDGIDRNDRY 

       610        620        630        640        650        660 
ANRNTVFFDI NLRGLDGLQG PVYVGTGCVF NRTALYGYEP PIKQKRPGYF SSLCGGRKKT 

       670        680        690        700        710        720 
KKSKEKSTEK KKSHKHVDSS VPVFNLEDIE EGIEGSGFDD EKSLLMSQMS LEKRFGQSSV 

       730        740        750        760        770        780 
FVASTLMEYG GVPQSATPES LLKEAIHVIS CGYEDKSDWG TEIGWIYGSV TEDILTGFKM 

       790        800        810        820        830        840 
HARGWRSIYC MPKRPAFKGS APINLSDRLN QVLRWALGSV EILFSRHCPI WYGYGGRLKF 

       850        860        870        880        890        900 
LERFAYINTT IYPLTSIPLL LYCILPAICL LTGKFIIPEI SNFASIWFIS LFLSIFATGI 

       910        920        930        940        950        960 
LEMRWSGVGI DEWWRNEQFW VIGGISAHLF AVFQGLLKVL AGIDTSFTVT SKASDEEGDF 

       970        980        990       1000       1010       1020 
AELYMFKWTT LLIPPTTILI INLVGVVAGI SYAINSGYQS WGPLFGKLFF AFWVIVHLYP 

      1030       1040       1050       1060       1070 
FLKGLMGRQN RTPTIVVVWA ILLASIFSLL WVRIDPFTTR VTGPDTQKCG INC

« Hide

References

« Hide 'large scale' references
[1]"Sequence, annotation, and analysis of synteny between rice chromosome 3 and diverged grass species."
The rice chromosome 3 sequencing consortium
Buell C.R., Yuan Q., Ouyang S., Liu J., Zhu W., Wang A., Maiti R., Haas B., Wortman J., Pertea M., Jones K.M., Kim M., Overton L., Tsitrin T., Fadrosh D., Bera J., Weaver B., Jin S. expand/collapse author list , Johri S., Reardon M., Webb K., Hill J., Moffat K., Tallon L., Van Aken S., Lewis M., Utterback T., Feldblyum T., Zismann V., Iobst S., Hsiao J., de Vazeille A.R., Salzberg S.L., White O., Fraser C.M., Yu Y., Kim H., Rambo T., Currie J., Collura K., Kernodle-Thompson S., Wei F., Kudrna K., Ammiraju J.S.S., Luo M., Goicoechea J.L., Wing R.A., Henry D., Oates R., Palmer M., Pries G., Saski C., Simmons J., Soderlund C., Nelson W., de la Bastide M., Spiegel L., Nascimento L., Huang E., Preston R., Zutavern T., Palmer L., O'Shaughnessy A., Dike S., McCombie W.R., Minx P., Cordum H., Wilson R., Jin W., Lee H.R., Jiang J., Jackson S.
Genome Res. 15:1284-1291(2005) [PubMed: 16109971] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Nipponbare.
[2]"The map-based sequence of the rice genome."
International rice genome sequencing project (IRGSP)
Nature 436:793-800(2005) [PubMed: 16100779] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Nipponbare.
[3]"The rice annotation project database (RAP-DB): 2008 update."
The rice annotation project (RAP)
Nucleic Acids Res. 36:D1028-D1033(2008) [PubMed: 18089549] [Abstract]
Cited for: GENOME REANNOTATION.
Strain: cv. Nipponbare.
[4]"The genomes of Oryza sativa: a history of duplications."
Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S., Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L. expand/collapse author list , Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J., Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X., Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y., Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L., Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H., Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z., Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L., Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F., Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q., Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J., Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M., McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.
PLoS Biol. 3:266-281(2005) [PubMed: 15685292] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Nipponbare.
[5]"Collection, mapping, and annotation of over 28,000 cDNA clones from japonica rice."
The rice full-length cDNA consortium
Science 301:376-379(2003) [PubMed: 12869764] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: cv. Nipponbare.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AC135958 Genomic DNA. Translation: AAP21426.1.
AC145384 Genomic DNA. Translation: AAS07381.1.
DP000009 Genomic DNA. Translation: ABF99460.1.
AP008209 Genomic DNA. Translation: BAF13562.1.
CM000140 Genomic DNA. Translation: EAZ28997.1.
AK069196 mRNA. No translation available.
RefSeqNP_001051648.1. NM_001058183.1.
UniGeneOs.59086.

3D structure databases

ProteinModelPortalQ84M43.
SMRQ84M43. Positions 13-71.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ84M43.

Protein family/group databases

CAZyGT2. Glycosyltransferase Family 2.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsLOC_Os03g59340.1; LOC_Os03g59340.1; LOC_Os03g59340.
GeneID4334515.
KEGGosa:4334515.

Organism-specific databases

GrameneQ84M43.

Phylogenomic databases

GeneTreeEPGT00070000027964.
HOGENOMHBG744549.
OMANIGRRGH.
PhylomeDBQ84M43.
ProtClustDBPLN02638.

Family and domain databases

InterProIPR005150. Cellulose_synth.
IPR001841. Znf_RING.
IPR013083. Znf_RING/FYVE/PHD.
[Graphical view]
Gene3DG3DSA:3.30.40.10. Znf_RING/FYVE/PHD. 1 hit.
KOK10999.
PfamPF03552. Cellulose_synt. 1 hit.
[Graphical view]
SMARTSM00184. RING. 1 hit.
[Graphical view]
PROSITEPS00518. ZF_RING_1. False negative.
PS50089. ZF_RING_2. False negative.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameCESA2_ORYSJ
AccessionPrimary (citable) accession number: Q84M43
Entry history
Integrated into UniProtKB/Swiss-Prot: February 26, 2008
Last sequence update: June 1, 2003
Last modified: December 14, 2011
This is version 70 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

Oryza sativa (rice)

Index of Oryza sativa entries and their corresponding gene designations

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents