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Protein

SWI/SNF complex subunit SWI3B

Gene

SWI3B

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at protein leveli

Functioni

Component of a multiprotein complex equivalent of the SWI/SNF complex, an ATP-dependent chromatin-remodeling complex, which is required for the positive and negative regulation of gene expression of a large number of genes. It changes chromatin structure by altering DNA-histone contacts within a nucleosome, leading eventually to a change in nucleosome position, thus facilitating or repressing binding of gene-specific transcription factors. May play an essential role in the transition from the vegetative to the reproductive phase of development. May be a positive regulator of ABA signaling.4 Publications

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Activator, Chromatin regulator, Developmental protein

Keywords - Biological processi

Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
SWI/SNF complex subunit SWI3B
Short name:
AtSWI3B
Alternative name(s):
Transcription regulatory protein SWI3B
Gene namesi
Name:SWI3B
Synonyms:CHB2
Ordered Locus Names:At2g33610
ORF Names:F4P9.38
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 2

Organism-specific databases

TAIRiAT2G33610.

Subcellular locationi

GO - Cellular componenti

  • nucleus Source: TAIR
  • SWI/SNF complex Source: TAIR
Complete GO annotation...

Keywords - Cellular componenti

Nucleus

Pathology & Biotechi

Disruption phenotypei

Plants have pleiotropic developmental abnormalities including embryo development blocked at the early globular stage.1 Publication

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003445281 – 469SWI/SNF complex subunit SWI3BAdd BLAST469

Proteomic databases

PaxDbiQ84JG2.
PRIDEiQ84JG2.

PTM databases

iPTMnetiQ84JG2.

Expressioni

Tissue specificityi

Expressed in roots, stems, leaves, flowers and siliques.2 Publications

Gene expression databases

GenevisibleiQ84JG2. AT.

Interactioni

Subunit structurei

Homodimers and heterodimers. Interacts with SWI3A, SWI3C, SWI3D, BSH, BRM and FCA (via C-terminus), and (via N-terminus) with HAB1. Interacts with MORC6 and SUVH9 (PubMed:27171427).5 Publications

Binary interactionsi

WithEntry#Exp.IntActNotes
ABI2O047192EBI-1102271,EBI-537680
HAB1Q9CAJ04EBI-1102271,EBI-2309302
SWI3CQ9XI074EBI-1102271,EBI-1102300

Protein-protein interaction databases

BioGridi3274. 70 interactors.
IntActiQ84JG2. 9 interactors.
STRINGi3702.AT2G33610.1.

Structurei

3D structure databases

ProteinModelPortaliQ84JG2.
SMRiQ84JG2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini48 – 145SWIRMPROSITE-ProRule annotationAdd BLAST98
Domaini223 – 274SANTPROSITE-ProRule annotationAdd BLAST52

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili423 – 447Sequence analysisAdd BLAST25

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi29 – 32Poly-Ala4
Compositional biasi40 – 43Poly-Ser4
Compositional biasi175 – 200Cys-richAdd BLAST26
Compositional biasi319 – 375Ala-richAdd BLAST57

Sequence similaritiesi

Contains 1 SANT domain.PROSITE-ProRule annotation
Contains 1 SWIRM domain.PROSITE-ProRule annotation

Keywords - Domaini

Coiled coil

Phylogenomic databases

eggNOGiKOG1279. Eukaryota.
COG5259. LUCA.
HOGENOMiHOG000238867.
InParanoidiQ84JG2.
KOiK11649.
OMAiTGCRTVC.
OrthoDBiEOG09360B8J.
PhylomeDBiQ84JG2.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
1.10.10.60. 1 hit.
InterProiIPR009057. Homeodomain-like.
IPR001005. SANT/Myb.
IPR017884. SANT_dom.
IPR032451. SMARCC_C.
IPR007526. SWIRM.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamiPF00249. Myb_DNA-binding. 1 hit.
PF04433. SWIRM. 1 hit.
PF16495. SWIRM-assoc_1. 1 hit.
[Graphical view]
SMARTiSM00717. SANT. 1 hit.
[Graphical view]
SUPFAMiSSF46689. SSF46689. 2 hits.
PROSITEiPS51293. SANT. 1 hit.
PS50934. SWIRM. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q84JG2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAMKAPDPGG SGEILPSTPS LSETTSGGAA AASKSAQLPS SSSDIDNIHV
60 70 80 90 100
PSYSSWFSWT DINDCEVRSL PEFFDSRSSS KNPKFYLYLR NSIIKQYRDD
110 120 130 140 150
HPRKISFTDV RRTLVSDVVS IRRVFDFLDS WGLINYNSSA SAKPLKWEEK
160 170 180 190 200
EAGKSAGDAA SEPATTVKET AKRNCNGCKA ICSIACFACD KYDLTLCARC
210 220 230 240 250
YVRSNYRVGI NSSEFKRVEI SEESKPEWSD KEILLLLEAV MHYGDDWKKV
260 270 280 290 300
ASHVIGRTEK DCVSQFVKLP FGEQFVKESD SEDGLEMFDQ IKDSDIPESE
310 320 330 340 350
GIDKDGSSPN KRIKLTPLAD ASNPIMAQAA FLSALAGTNV AEAAARAAVR
360 370 380 390 400
ALSDVDYEAD KNASRDPNRQ DANAASSGET TRNESERAWA DAKSLIEKEE
410 420 430 440 450
HEVEGAIKET VEVEMKKIRD RIVHFEKLDL EMERSRKQLE EVRNLLFVDQ
460
LNIFFHTRKA RKTEDRIEC
Length:469
Mass (Da):52,411
Last modified:June 1, 2003 - v1
Checksum:iBB4D35067B8520E1
GO

Sequence cautioni

The sequence AAB80676 differs from that shown. Reason: Erroneous gene model prediction.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC002332 Genomic DNA. Translation: AAB80676.1. Sequence problems.
CP002685 Genomic DNA. Translation: AEC08859.1.
BT004085 mRNA. Translation: AAO42112.1.
BT005094 mRNA. Translation: AAO50627.1.
PIRiF84747.
RefSeqiNP_180919.2. NM_128921.6.
UniGeneiAt.43725.

Genome annotation databases

EnsemblPlantsiAT2G33610.1; AT2G33610.1; AT2G33610.
GeneIDi817927.
GrameneiAT2G33610.1; AT2G33610.1; AT2G33610.
KEGGiath:AT2G33610.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC002332 Genomic DNA. Translation: AAB80676.1. Sequence problems.
CP002685 Genomic DNA. Translation: AEC08859.1.
BT004085 mRNA. Translation: AAO42112.1.
BT005094 mRNA. Translation: AAO50627.1.
PIRiF84747.
RefSeqiNP_180919.2. NM_128921.6.
UniGeneiAt.43725.

3D structure databases

ProteinModelPortaliQ84JG2.
SMRiQ84JG2.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi3274. 70 interactors.
IntActiQ84JG2. 9 interactors.
STRINGi3702.AT2G33610.1.

PTM databases

iPTMnetiQ84JG2.

Proteomic databases

PaxDbiQ84JG2.
PRIDEiQ84JG2.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT2G33610.1; AT2G33610.1; AT2G33610.
GeneIDi817927.
GrameneiAT2G33610.1; AT2G33610.1; AT2G33610.
KEGGiath:AT2G33610.

Organism-specific databases

TAIRiAT2G33610.

Phylogenomic databases

eggNOGiKOG1279. Eukaryota.
COG5259. LUCA.
HOGENOMiHOG000238867.
InParanoidiQ84JG2.
KOiK11649.
OMAiTGCRTVC.
OrthoDBiEOG09360B8J.
PhylomeDBiQ84JG2.

Miscellaneous databases

PROiQ84JG2.

Gene expression databases

GenevisibleiQ84JG2. AT.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
1.10.10.60. 1 hit.
InterProiIPR009057. Homeodomain-like.
IPR001005. SANT/Myb.
IPR017884. SANT_dom.
IPR032451. SMARCC_C.
IPR007526. SWIRM.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamiPF00249. Myb_DNA-binding. 1 hit.
PF04433. SWIRM. 1 hit.
PF16495. SWIRM-assoc_1. 1 hit.
[Graphical view]
SMARTiSM00717. SANT. 1 hit.
[Graphical view]
SUPFAMiSSF46689. SSF46689. 2 hits.
PROSITEiPS51293. SANT. 1 hit.
PS50934. SWIRM. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiSWI3B_ARATH
AccessioniPrimary (citable) accession number: Q84JG2
Secondary accession number(s): O22811
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 22, 2008
Last sequence update: June 1, 2003
Last modified: November 30, 2016
This is version 117 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.